Abstract: The current application is directed to cosmetic methods for changing the appearance of eyes by causing a retraction of the eyelids so that the eyes appear to be more open and have a wider appearance. Various methods involve application of one or more prostaglandins, synthetic prostaglandins, including synthetic prostaglandin F, and synthetic prostaglandin analogues, to eyelids, which results in contraction of eyelid muscles and a wider, more open appearance of the eyes.

Abstract: Surgical constructs and methods are provided for securing soft tissue to bone. One exemplary embodiment of a construct is formed from a suture filament and includes two terminal ends of filament and an intermediate portion disposed along at least a portion of a length extending between the terminal ends. The construct can have a first terminal end that is the first terminal end of the filament, and a second terminal end that includes a loop. The loop can be formed by disposing the second terminal end of the filament within a volume of a portion of the intermediate portion of the filament. In some disclosed methods, both terminal ends of the filament can be passed through tissue when performing soft tissue repairs. Various other embodiments of constructs and methods are provided, including constructs having two or more filaments associated with an anchor and methods of using such constructs.

Abstract: An apparatus for controlling a target device including a first input device configured to provide a first input to the target device, a second input device configured to provide a second input to the target device, and a control mixer configured to generate an output using a policy, the first input and the second input, wherein the output comprises a feedback and a target device output, wherein the feedback comprises some function of the state of the target device, the policy, and the state of each input device connected to the control mixer.

Abstract: Various embodiments provide an interactive, shared, story-reading experience in which stories can be experienced from remote locations. Various embodiments enable augmentation or modification of audio and/or video associated with the story-reading experience. This can include augmentation and modification of a reader's voice, face, and/or other content associated with the story as the story is read.

Abstract: Various embodiments provide an interactive, shared, story-reading experience in which stories can be experienced from remote locations. Various embodiments enable augmentation or modification of audio and/or video associated with the story-reading experience. This can include augmentation and modification of a reader's voice, face, and/or other content associated with the story as the story is read.

Abstract: Various embodiments provide an interactive, shared, story-reading experience in which stories can be experienced from remote locations. Various embodiments enable augmentation or modification of audio and/or video associated with the story-reading experience. This can include augmentation and modification of a reader's voice, face, and/or other content associated with the story as the story is read.

Abstract: A method includes generating a first table having a set of attributes for each file in a first set of files associated with a first computer user. The set of attributes for each file in the first set of files have a plurality of attribute types. The method further includes generating a second table having a set of attributes for each file in a second set of files associated with a second computer user. The set of attributes for each file in the second set of files have the plurality of attribute types. The method further includes generating a similarity table by comparing each set of attributes in the first table with each set of attributes in the second table, utilizing a predetermined similarity metric, and determining whether the first and second computer users have at least one file with common attributes, based on data in the similarity table.

Abstract: The present invention shows that intranasal administration of E1/E3-defective adenovirus particles may confer rapid and broad protection against viral and bacterial pathogens in a variety of disease settings. Protective responses lasted for many weeks in a single-dose regimen in animal models. When a pathogen-derived antigen gene was inserted into the E1/E3-defective adenovirus genome, the antigen-induced protective immunity against the specific pathogen was elicited before the adenovirus-mediated protective response declined away, thus conferring rapid, prolonged, and seamless protection against pathogens. In addition to E1/E3-defective adenovirus, other bioengineered non-replicating vectors encoding pathogen-derived antigens may also be developed into a new generation of rapid and prolonged immunologic-therapeutic (RAPIT).

Abstract: Disclosed and claimed is a method of non-invasive immunization in an animal and/or a method of inducing a systemic immune response or systemic therapeutic response to a gene product. The skin of the animal is contacted with a non-replicative vector chosen from the group of bacterium, virus, and fungus, wherein the vector comprises and expresses a nucleic acid molecule encoding the gene product, in an amount effective to induce the response.

Abstract: The present invention relates generally to the fields of immunology and vaccine technology. More specifically, the invention relates to recombinant human adenovirus vectors for delivery of avian immunogens and antigens, such as avian influenza into avians. The invention also provides methods of introducing and expressing an avian immunogen in avian subjects, including avian embryos, as well as methods of eliciting an immunogenic response in avian subjects to avian immunogens.

Abstract: A device for identifying infection by the malaria parasite includes a microfluidic device having an inlet and an outlet and a diagnostic channel interposed between the inlet and the outlet. The diagnostic channel includes a contact surface and a sample pump configured to pump a RBC-containing sample into the inlet. The contact surface may be at least one of hydrophilic and roughened. Malaria infected RBCs (miRBCs) interact with the contact surface and become immobilized thereon whereas non-infected RBCs continue to flow downstream in the diagnostic channel.

Abstract: An active guidelines capability or component is linked to a computerized patient record system to integrate the use of clinical guidelines in the workflow of clinicians treating patients. Many healthcare entities maintain sets of clinical guidelines describing recommended treatment or analysis options for patients displaying sets of symptoms or for whom certain diagnoses have been made. The active guidelines feature adds an active guidelines tag to such clinical guidelines so that when the clinician accesses the clinical guidelines and wishes to follow the recommendation, the clinician merely has to click on a hypertext created from the tag which then transmits action orders, also contained in the tag, to be transmitted to the computerized patient record system for implementation. Patient data associated with the recommendations, such as relevant test or lab results, interaction or allergy information, or other current treatments, is also identified and displayed.

Abstract: A communication system is described herein which provides an indicator that helps hub participants of a meeting (or other environmental setting) determine a direction of attention of a satellite participant (who is not physically present at the meeting). The indicator can be implemented as a mechanical pointer, a solid-state display mechanism, a rotating display mechanism, a display mechanism which presents visual information that reflects directionality, and so on. The communication system can assess the directionality of the satellite participant based on any combination of control inputs from explicit input mechanism(s) and/or implicit input mechanism(s). The communication system can also choose between explicit and/or implicit control of the indicator based on at least one selection criterion.

Abstract: A communication system is described herein which provides an indicator that helps hub participants of a meeting (or other environmental setting) determine a direction of attention of a satellite participant (who is not physically present at the meeting). The indicator can be implemented as a mechanical pointer, a solid-state display mechanism, a rotating display mechanism, a display mechanism which presents visual information that reflects directionality, and so on. The communication system can assess the directionality of the satellite participant based on any combination of control inputs from explicit input mechanism(s) and/or implicit input mechanism(s). The communication system can also choose between explicit and/or implicit control of the indicator based on at least one selection criterion.

Abstract: Embodiments described herein relate to enabling a lightweight way of recording and sharing video messages intended to provide input to a future meeting that cannot be personally attended. A person who cannot attend the meeting pre-records their thoughts and remarks for the meeting as video clips for presentation at the meeting. A physical device with at least a display is presented at the meeting. The physically present participants can play the pre-recorded clips on the device. Video of participants' responses to the clips is recorded and made available so that the represented attendee can view the participants' responses.

Abstract: A neural probe device includes a housing configured to receive a nerve fiber of a subject and an anchor disposed within the housing and configured to fix the nerve fiber relative to the housing. The device further includes a plurality of actuatable, moveable electrodes disposed in the housing along a length of the nerve fiber, each moveable electrode comprising a plurality of projections containing one or more electrodes thereon, wherein actuation of the moveable electrode causes the moveable electrode to move generally transverse to a long axis of the nerve fiber and penetrate the nerve fiber with the plurality of projections. The device is also optionally configured to inject a growth factor into the nerve fiber to maintain the viability of the nerve fiber.

Abstract: A method for assisting an administrator to identify files suspected of causing instability on a personal computer comprises periodically creating file content sharing logs concurrently with archiving files of a plurality of personal computers by de-duplicating, when a notification is received regarding instability of a personal computer, then analyzing archive file content sharing log of the personal computer made immediately after receiving the notification for unique system and program files, missing files and newly installed files to generate an instability report. A missing or corrupted file can be restored back on the unstable personal computer by performing a backup restore operation on the unstable personal computer.

Abstract: The current application is directed to a moisture-and-UV barrier that can be applied to a corner of a deck cap during deck construction or subsequently retrofit to the corner of the deck cap in order to prevent deterioration of the deck cap and of the deck structure below the deck cap. The moisture-and-UV barrier includes a waterproof, UV-resistant, and crack-and-tear resistant top surface that conforms to the top surface of the deck-cap corner as well as vertical sides that together enclose a portion of the deck cap at the deck corner to prevent exposure of the miter joint between deck-cap members at the deck-cap corner to UV radiation, water, and other harmful substances and agents.

Abstract: A neural probe device includes a housing configured to receive a nerve fiber of a subject and an anchor disposed within the housing and configured to fix the nerve fiber relative to the housing. The device further includes a plurality of actuatable, moveable electrodes disposed in the housing along a length of the nerve fiber, each moveable electrode comprising a plurality of projections containing one or more electrodes thereon, wherein actuation of the moveable electrode causes the moveable electrode to move generally transverse to a long axis of the nerve fiber and penetrate the nerve fiber with the plurality of projections. The device is also optionally configured to inject a growth factor into the nerve fiber to maintain the viability of the nerve fiber.