Abstract: Compounds having the formula ##STR1## wherein R.sub.1 is hydrogen, halogen, alkyl alkoxy or nitro; R.sub.2 is hydrogen, halogen or alkoxy; R.sub.3 is an imidazol-4-yl or indol-3-yl; and n is 1,2,3 or 4, have antiinflammatory activity.

Abstract: 2,3-Dihydro-1,2,4-triazolo[4,3-b][1,2]benzisothiazol-3-amine, 5,5-dioxides having the formula ##STR1## and salts thereof are new compounds which are useful as anti-inflammatory agents.

Abstract: Benzimidazolecarbamate derivatives are provided having the structure ##STR1## wherein R is lower alkyl, R.sub.1, R.sub.2 and R.sub.3 may be the same or different and may be lower alkyl or lower alkoxy, m is 0, 1 or 2 and n is 1 to 5. These compounds are useful as anthelmintic agents.

Abstract: A common-drain high frequency power oscillator is configured by electrically reversing the channel of a GaAsFET transistor. Such an oscillator can be flip-chip mounted for reduced thermal resistance and has superior oscillation characteristics as compared with conventional common-source oscillators. Specifically, its gain is nearly constant with frequency, oscillation is less critically dependent on terminal impedance, and it can be operated with a single polarity voltage supply.

Abstract: An environmentally conditioned enclosure adapted for human habitation and construction methods relating to same. A foundation comprised of thermally insulative material provides support for a shelter erected thereon, and dividably defines a separate geothermal heat exchange region isolated from surrounding ground. The foundation is located within a trench which must be excavated around the separate geothermal region. A geothermal heat exchanger buried within this separate region receives fluids circulated between it and the shelter. By locating the geothermal heat exchanger apparatus in an underground region separate from surrounding ground, an enhanced time lag between variations in outside surface temperature and variations in underground temperatures is achieved. The shelter is preferably secured to the foundation by a liquid anchor received within a channel provided in the foundation.

Abstract: Triazoloisoindoles are provided having the structure ##STR1## wherein X, Y and R are as defined hereinafter. These compounds have antiinflammatory activity and anthelmintic activity. Pharmaceutical compositions containing such compounds and methods for using such compounds are also provided.

Abstract: Compounds of the following formula ##STR1## wherein R.sup.1 and R.sup.2 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, and trifluoromethyl, and R is selected from a triacetyl substituted pentose, pentose, a tetraacetyl substituted hexose, hexose, a hydroxy substituted cycloalkyl of 5 to 7 carbons, ##STR2## wherein n is 1 or 2 ad R.sup.3 is hydrogen, an alkali metal or alkaline earth metal ion; are disclosed. These compounds possess useful anti-inflammatory activity.

Abstract: 2-Substituted benzisothiazol-3-ones are provided having the structure ##STR1## wherein R is hydrogen, halogen, lower alkyl, lower alkoxy, or nitro; R.sup.1 is hydrogen, lower alkoxy or halogen, with the proviso that R.sup.1 can be lower alkoxy or halogen only when R is lower alkoxy or halogen, respectively; X is hydrogen, halogen, lower alkyl, lower alkoxy, or trifluoromethyl; Y is C or N, where Y is C, --------represents a single or double bond, and when Y is N, --------represents a single bond, p is 0 or 2, A is an alkylene group containing 2 to 5 carbons in the normal chain; and B is a single bond or an alkylene group containing from 1 to 3 carbons in the normal chain, and physiologically acceptable acid-addition salts thereof.These compounds have antiinflammatory activity, sedative and muscle relaxant activity. Pharmaceutical compositions containing such compounds and methods for using such compounds are also provided.

Abstract: New triazolobenzisothiazole-1,1-dioxides which have the formula ##STR1## wherein R is hydrogen, lower alkyl, phenyl or substituted phenyl;X is hydrogen, halogen, lower alkyl, lower alkoxy or nitro; andY is hydrogen, halogen or lower alkoxy,Are useful as anti-inflammatory agents.

Abstract: 3-Substituted benzisothiazole, 1,1-dioxides are provided having the structure ##STR1## wherein R is hydrogen, halogen, lower alkyl, lower alkoxy, or nitro; R.sup.1 is hydrogen, lower alkoxy or halogen with the proviso that R.sup.1 can be lower alkoxy or halogen only when R is lower alkoxy or halogen, respectively; Y is C or N, where Y is C, may represent a double bond, and when Y is N, represents a single bond, A is a single bond or an alkylene group containing from 1 to 4 carbons, and B is hydrogen, hydroxyl, phenyl or phenyl substituted with halogen, lower alkyl, lower alkoxy, or trifluoromethyl, with the proviso that when Y is C, B is phenyl or substituted phenyl, and when Y is N and B is hydrogen, A has at least 1 carbon and when B is hydroxyl, A has at least 2 carbons; and physiologically acceptable acid-addition salts thereof where Y is N. These compounds are useful as antiinflammatory agents.

Abstract: 3-(Arylcycloiminoalkyl)benzisothiazole 1,1-dioxides are provided having the structure ##STR1## wherein R is hydrogen, halogen, lower alkyl, lower alkoxy or nitro; R.sup.1 is hydrogen, lower alkoxy or halogen with the proviso that R.sup.1 can be lower alkoxy or halogen only when R is lower alkoxy or halogen, respectively; A is O or NH; X is hydrogen, halogen lower alkyl, lower alkoxy, or trifluoromethyl; Y is C or N, where Y is C, is a double bond, and when Y is N, represents a single bond, B is an alkylene group containing 2 to 5 carbons in the normal chain; Q is a single bond or an alkylene group containing 1 to 3 carbons in the normal chain; and physiologically acceptable acid-addition salts thereof. These compounds are useful as antiinflammatory agents.

Abstract: Triazoloisoindoles are provided having the structure ##STR1## wherein X, Y and R are as defined hereinafter. These compounds have antiinflammatory activity and anthelmintic activity. Pharmaceutical compositions containing such compounds and methods for using such compounds are also provided.

Abstract: Compounds of the following formula ##STR1## wherein R.sup.1 and R.sup.2 are selected from hydrogen, lower alkyl, lower alkoxy, lower alkylthio, halogen, trifluoromethyl, nitro, amino and cyano; Z is selected from ##STR2## R.sup.3 is selected from phenyl, phenyl-lower alkyl, substituted phenyl, and substituted phenyl-lower alkyl; R.sup.4 is selected from R.sup.3 and a 6-membered unsaturated substituted or unsubstituted heterocyclic ring selected from pyridine, diazine and triazine; and A is a straight or branched chain alkylene of 2 to 8 carbons are disclosed. These compounds exhibit antidepressant activity.

Abstract: Triazolo-2,4-benzodiazepines are provided having the structure ##STR1## wherein X, Y and R are as defined hereinafter. These compounds have antiinflammatory activity, and sedative, anxiolytic, and muscle relaxant activity. Pharmaceutical compositions containing such compounds and method for using such compounds are also provided.

Abstract: Compounds of the following formula and their acid addition salts ##STR1## Z is ##STR2## A is straight or branched chain alkylene of 2 to 6 carbons; B is straight chain alkylene of 2 to 4 carbons; X is straight or branched chain alkyl of 1 to 8 carbons, phenyl, benzyl, phenethyl, substituted phenyl, substituted benzyl, or substituted phenethyl, R.sub.1 and R.sub.2 are located at the 7 or 8 and 5 or 6 position respectively and are independently selected from the group consisting of hydrogen, straight or branched chain alkyl of 1 to 4 carbons, straight or branched chain alkoxy of 1 to 4 carbons, Cl, Br, F, amino, nitro, CF.sub.3, and cyano; are disclosed. These compounds possess antiprotozoal activity.

Abstract: Compounds of the following formula and their acid addition salts ##STR1## A is straight or branched chain alkylene of 2 to 6 carbons; R.sub.1 and R.sub.2 are located at the 7 or 8 and 5 or 6 position respectively and are independently selected from the group consisting of hydrogen, straight or branched chain alkyl of 1 to 4 carbons, straight or branched chain alkoxy of 1 to 4 carbons, Cl, Br, F, amino, nitro, cyano, and CF.sub.3 ; R.sub.3 and R.sub.4 are independently selected from the group consisting of hydrogen and straight or branched chain alkyl of 1 to 4 carbons; and n is 1, 2, or 3; m is 1 or 2; are disclosed. These compounds possess anti-protozoal activity.

Abstract: Compounds of the following formula ##STR1## wherein R.sup.1 and R.sup.2 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, and trifluoromethyl, and R is selected from a triacetyl substituted pentose, pentose, a tetraacetyl substituted hexose, hexose, a hydroxy substituted cycloalkyl of 5 to 7 carbons, ##STR2## wherein n is 1 or 2 and R.sup.3 is hydrogen, an alkali metal or alkaline earth metal ion; are disclosed. These compounds possess useful anti-inflammatory activity.

Abstract: This invention provides a method and apparatus for expanding spiralweld pipe. The expander head is cantilevered at a fixed location and the spiralweld pipe is advanced in stages around the expander head, moving in the direction of the pipe axis. At each stage, the pipe is stopped, and the expander head is expanded to cause expansion in the pipe. The expander head has on its surface a helically arranged recess matching the main weld of the pipe. As the pipe is moved between adjacent expansion locations, it undergoes axial and rotational motion so that the main weld tracks in registry with the recess.

Abstract: Compounds having the formula ##STR1## wherein A is a straight or branched chain alkylene group; R is hydrogen, halogen, alkyl, alkoxy, alkylthio, trifluoromethyl, nitro, amino, or cyano; and m is 2, 3 or 4; are useful in the treatment of allergic conditions in mammals.

Abstract: Compounds having the structure ##STR1## wherein R.sub.1 is hydrogen, alkyl, phenyl, or benzyl; R.sub.2 is hydrogen or alkyl; R.sub.3 is hydrogen, alkyl, haloalkyl, cyanoalkyl, trifluoromethyl, phenyl, benzyl, ##STR2## OR --(CH.sub.2).sub.n --NR.sub.5 R.sub.6 ; R.sub.4 is hydrogen, halogen, nitro, cyano, trifluoromethyl, alkyl, alkoxy, or alkylthio; R.sub.5 and R.sub.6 are the same or different and are hydrogen or alkyl or R.sub.5 and R.sub.6 together with the nitrogen atom to which they are attached form a five or six membered heterocyclic ring; and n is 1, 2, 3 or 4; are useful as anti-inflammatory agents.