Abstract: Techniques, systems and apparatus are described for magnetic resonance imaging by modifying the shape/thickness of an excitation/inversion slab. For instance, the inversion slab can be shaped as a wedge to improve temporal signal-to-noise ratio (tSNR) of arterial spin labeling (ASL) experiments by matching the temporal bolus width with the inter-pulse spacing in different feeding arteries. The shape/thickness of the excitation/inversion slab across the X-Y plane can be modified by modulating the movement of the “on-resonance” plane in space by the combination of conventional slice-selective (SS) adiabatic fast passage (AFP) and additional in-plane gradient pulses. Using this method, a computer can generate different shapes of the excitation/inversion slab.

Abstract: A method for registering an imaging detector to a surface projects and records a sequence having a first sparse pattern of lines followed by a second sparse pattern of lines. A first subset of positions receives lines from both first and second sparse patterns corresponding to a first label. A second subset of positions receives only lines from the first sparse pattern corresponding to a second label. A third subset of positions receives only lines from the second sparse pattern corresponding to a third label. The first, second, and third labels are decoded and each member element of the first, second, and third subsets of positions registered to the imaging detector according to the decoded labels. One or more dense patterns of lines positionally correlated with registered member elements of the decoded labels are projected and recorded. An image of the surface contour is formed according to the recorded pattern.

Abstract: According to one configuration, a shared wireless access node supports wireless access for multiple wireless network service providers. A mobile communication device receives notification of multiple wireless network service providers, each of which provides access to a remote network through the shared wireless access node. The notification includes connection information such as priority information assigned to the wireless network service providers. The priority information indicates an order in which to select amongst the multiple available wireless network service providers to access the remote network. Based at least in part on the priority information, the mobile communication device selects a wireless network service provider amongst the multiple wireless network service providers.

Abstract: An apparatus for oral imaging has a light source energizable to generate a light frequency signal ranging from a minimum to a maximum frequency. An image acquisition apparatus scans the generated light frequency signal to successive positions on a sample surface and to combine a returned signal from each successive position with the generated light frequency signal. The image acquisition apparatus has a detector that obtains a beat frequency signal from the combined returned signal and the generated light frequency signal. A processor that is in signal communication with the detector generates a processed beat signal from the combined signals, wherein the processed beat signal is indicative of the distance from the tunable laser source to the sample surface at the corresponding position. A display is in signal communication with the processor and is energizable to display distance data according to the processed beat signal for each scanned position.

Abstract: An integrated circuit is described. The integrated circuit comprises a first portion having programmable resources; a second portion having hardened circuits including an analog-to-digital converter circuit configured to receive an input signal and generate an output signal; and a monitor circuit configured to receive an output signal generated by the analog-to-digital converter circuit; wherein the monitor circuit is configurable to control a calibration of the analog-to-digital converter circuit based upon signal characteristics of the output signal generated by the analog-to-digital converter circuit. A method of receiving data in an integrated circuit is also described.

Abstract: An apparatus for intraoral imaging has an intraoral camera that defines a field of view with a first dimension and a second dimension orthogonal to the first dimension. A projector has a laser diode energizable to emit a light beam; a collimator in the path of the emitted light beam; first beam-shaping optics disposed to shape the collimated light beam in the second dimension to form a linear light pattern; focusing optics disposed to focus the shaped collimated beam at a focal plane; and a scanner that is disposed substantially at the focal plane and that is energizable to scan the formed linear light pattern along the second dimension to successive positions of the field of view. A control logic processor coordinates energizing the laser diode and scanner with image capture by the intraoral camera.

Abstract: The invention provides methods of treating neoplasia, for example bladder cancer, by administering an IL-2 fusion protein and one or more therapeutic agents, where the IL-2 fusion protein does not necessarily have to target the neoplasia.

Abstract: Method and/or apparatus embodiments for 3-D cephalometric analysis of a patient according to the application can display reconstructed volume image data from a computed tomographic scan of a patient's head including segmented dentition elements having an initial arrangement from one or more 2D/3D views; can compute and display a plurality of cephalometric parameters for the patient according to the reconstructed volume image data; then use the patient specific cephalometric parameters and population biometry data, to identify one or more maxillofacial/dental abnormalities; and compose patient specific treatment plans to correct selected dentition abnormalities using maxillofacial/dental structure, which can be composed in a final tooth arrangement in a final virtual CT volume. One or more aligners can be generated to incrementally move dentition from the initial arrangement to the final tooth arrangement.

Abstract: Contemplated compositions and methods comprise chimeric molecule complexes that advantageously provide activating signaling to immune competent cells when bound to ALL cells. Furthermore, chimeric molecule complexes include an Fc portion to extend serum half live time and facilitate purification.

Abstract: Systems and techniques that provide context-aware badge display in online communities are disclosed. Badges are identified for display based on the contexts of the online interfaces in which the badges will be displayed. When the badges awarded to a user are to be displayed in a particular online interface, the online community of that online interface is identified and used to display appropriate badges. Badges awarded to the user in the particular online community of the online interface and one or more related online communities are displayed. The related communities are identified based on a hierarchy of communities that identifies relationships between the online communities. Badges can be displayed using different display rules that can be changed over time and vary for different online communities.

Abstract: The instant invention provides soluble fusion protein complexes and IL-15 variants that have therapeutic and diagnostic use, and methods for making the such proteins. The instant invention additionally provides methods of stimulating or suppressing immune responses in a mammal using the fusion protein complexes and IL-15 variants of the invention.

Abstract: A communication management resource receives first input registering user equipment to use wireless network services of a first wireless network and a second wireless network. The communication management resource receives second input from the user equipment registering the user equipment to use voice services. In response to receiving a phone communication indicating a corresponding phone call, the communication management resource selects a transport protocol from multiple possible transport protocols to establish a communication session between the communication management resource and the user equipment. The communication management resource initially establishes a communication link or communication session for the corresponding phone call over the first wireless network between the user equipment and the communication management resource using the selected transport protocol.

Abstract: A waveguide includes a core and an electrically-conductive transmission line. The core includes an electrically-insulating material that is transmissive at millimeter-wave frequencies. The core is configured to receive a millimeter-wave signal at a first end of the waveguide, and to guide the millimeter-wave signal to a second end of the waveguide. The electrically-conductive transmission line is coupled in propinquity to the core and is configured to conduct an electrical signal between the first end of the waveguide and the second end of the waveguide, in parallel with the millimeter-wave signal guided in the core.

Abstract: Embodiments of the disclosure include methods of prenatal testing using non-invasive means that identify single gene disorders. In specific embodiments the methods are non-invasive and employ tagging circulating cell-free fetal DNA from the biological mother with particular adaptors that employ unique barcodes, followed by steps to enrich targets and steps for thorough sequencing.

Abstract: User equipment receives first connection priority information. In accordance with the first connection priority information, the mobile communication device establishes a first wireless communication link between the user equipment and a first wireless network to communicate first communications. A controller/management resource provides notification of second connection priority information to be used instead of the first connection priority information. In response to detecting a trigger event in which the user equipment is operated to communicate second communications, the user equipment uses the second connection priority information as a replacement to the first connection priority information to establish a second wireless communication link connecting the user equipment to the second network instead of the first network.

Abstract: An SRAM cell with dynamic split ground (GND) and split wordline (WL) for extreme scaling is disclosed. The memory cell includes a first access transistor enabled by a first wordline to control access to cross coupled inverters by a first bitline. The memory cell further includes a second access transistor enabled by a second wordline to control access to the cross coupled inverters by a second bitline. The memory cell further includes a split ground line comprising a first ground line (GNDL) separated from a second ground line (GNDR). The GNDL is connected to a transistor of a first inverter of the cross coupled inverters and the GNDR is connected to a first transistor of a second inverter of the cross coupled inverters.

Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-7 or IL-21.

Abstract: The present invention provides thiazole compounds of Formula I wherein W, Y, R0, R2, R4, R5, R6, R7, X1, X2, X3 and X4 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.

Abstract: A master/slave configuration of a frequency locked Loop (FLL) decouples the process, target voltage, temperature (PVT) tracking goals of locking the loop from adapting the clock frequency in response to voltage droops in the supply. A master oscillator circuit receives a regulated supply voltage and supplies a master oscillator signal. A control circuit supplies a master frequency control signal to control a frequency of the master oscillator signal to a target frequency. A slave oscillator circuit is coupled to a regulated supply voltage and a droopy supply voltage and supplies a slave oscillator signal having a frequency responsive to a slave frequency control signal that is based on the master frequency control signal. The frequency of the second oscillator signal is further responsive to a voltage change of the droopy supply voltage.

Abstract: Disclosed are compositions and methods for detecting cells or tissue comprising a peptide antigen presented in the context of an MHC or HLA complex. The invention has a wide range of applications including providing a highly sensitive method for detecting cancer cells.