Patents by Inventor C. Wong

C. Wong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190067100
    Abstract: Embodiments are directed to a semiconductor device. The semiconductor device includes a first semiconductor fin formed opposite a surface of a first active region of a substrate. The semiconductor device further includes a second semiconductor fin formed opposite a surface of a second active region of the substrate. The semiconductor device further includes a self-aligned buried contact formed over portions of the first active region and the second active region and between the first semiconductor fin and the second semiconductor fin.
    Type: Application
    Filed: August 25, 2017
    Publication date: February 28, 2019
    Inventors: Su Chen Fan, Jeffrey C. Shearer, Robert C. Wong, Ruilong Xie
  • Patent number: 10212256
    Abstract: The disclosure is directed to pushing data updates to client computing devices (“clients”) in real-time. Clients can obtain data from a data storage layer by sending queries to the data storage layer that will return data compatible with the client's local data model. These queries are stored in a database and the identifier for the query (“query ID”) is used instead of the query itself. In the query stored in the database, a marker is used as a proxy for a content ID of the content to be retrieved. When querying, both the query ID and the content ID are passed to the data storage layer. The query stored with the query id is loaded, the marker is substituted with the content ID, and then executed.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: February 19, 2019
    Assignee: Facebook, Inc.
    Inventors: Sean Bradley Quinlan, Harrison C. Wong, Jeremy David Fein
  • Publication number: 20190048055
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Application
    Filed: March 27, 2018
    Publication date: February 14, 2019
    Inventors: Niraj Shrestha, Bai Liu, Peter Rhode, Hing C. Wong
  • Publication number: 20190046623
    Abstract: The invention features multi-specific fusion protein complexes with one domain comprising IL-15 or a functional variant and a binding domain specific to IL-12 or IL-18.
    Type: Application
    Filed: March 6, 2018
    Publication date: February 14, 2019
    Inventors: Warren D. Marcus, Robert Newman, Bai Liu, Lijing You, Lin Kong, Peter Rhode, Hing C. Wong
  • Publication number: 20190023766
    Abstract: The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor ?/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus).
    Type: Application
    Filed: April 11, 2018
    Publication date: January 24, 2019
    Inventors: Hing C. Wong, Peter Rhode, Bai Liu, Xiaoyun Zhu, Kai-Ping Han
  • Publication number: 20190022187
    Abstract: The invention features combination therapies using an IL-15-based superagonist complex and an antibody to effectively treat subjects with cancer and infectious diseases.
    Type: Application
    Filed: March 14, 2018
    Publication date: January 24, 2019
    Inventors: Bai Liu, Peter Rhode, Wenxin Xu, Hing C. Wong
  • Publication number: 20180372756
    Abstract: Chimeric proteins comprising an N-terminal domain derived from an N-terminal nucleotide binding domain of TDP-43 and a C-terminal domain derived from a splicing repressor are described. These proteins may be administered to a subject to treat or prevent disease manifesting TDP-43 proteinopathy such as inclusion body myocytosis, amyotrophic lateral sclerosis (ALS), or frontotemporal dementia (FTD).
    Type: Application
    Filed: June 17, 2016
    Publication date: December 27, 2018
    Inventors: Philip C. Wong, Jonathan P. Ling
  • Publication number: 20180368774
    Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.
    Type: Application
    Filed: June 22, 2018
    Publication date: December 27, 2018
    Inventors: John Michael Gray, Jennifer Blackwell, Paul V. Neale, Justen Deering England, Andrew Joncich, Cameron Brock, Peter C. Simpson, Thomas Metzmaker, Neel Narayan Shah, Mark Douglas Kempkey, Patrick John Castagna, Warren Terry, Jason Halac, Christian Michael Andre George, Daniel E. Apacible, John Charles Barry, Maria Noel Brown Wells, Kenneth Pirondini, Andrew Michael Reinhardt, Jason C. Wong, Remy E. Gagnon, David DeRenzy, Randall Scott Koplin, Alan Baldwin, Young Woo Lee, David A. Keller, Louise Emma van den Heuvel, Carol Wood Sutherland
  • Publication number: 20180368773
    Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.
    Type: Application
    Filed: June 22, 2018
    Publication date: December 27, 2018
    Inventors: John Michael Gray, Jennifer Blackwell, Paul V. Neale, Justen Deering England, Andrew Joncich, Cameron Brock, Peter C. Simpson, Thomas Metzmaker, Neel Narayan Shah, Mark Douglas Kempkey, Patrick John Castagna, Warren Terry, Jason Halac, Christian Michael Andre George, Daniel E. Apacible, John Charles Barry, Maria Noel Brown Wells, Kenneth Pirondini, Andrew Michael Reinhardt, Jason C. Wong, Remy E. Gagnon, David DeRenzy, Randall Scott Koplin, Alan Baldwin, Young Woo Lee, David A. Keller, Louise Emma van den Heuvel, Carol Wood Sutherland
  • Publication number: 20180368772
    Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.
    Type: Application
    Filed: June 22, 2018
    Publication date: December 27, 2018
    Inventors: John Michael Gray, Jennifer Blackwell, Paul V. Neale, Justen Deering England, Andrew Joncich, Cameron Brock, Peter C. Simpson, Thomas Metzmaker, Neel Narayan Shah, Mark Douglas Kempkey, Patrick John Castagna, Warren Terry, Jason Halac, Christian Michael Andre George, Daniel E. Apacible, John Charles Barry, Maria Noel Brown Wells, Kenneth Pirondini, Andrew Michael Reinhardt, Jason C. Wong, Remy E. Gagnon, David DeRenzy, Randall Scott Koplin, Alan Baldwin, Young Woo Lee, David A. Keller, Louise Emma van den Heuvel, Carol Wood Sutherland
  • Publication number: 20180368771
    Abstract: The present embodiments relate generally to applicators of on-skin sensor assemblies for measuring an analyte in a host, as well as their method of use and manufacture. In some aspects, an applicator for applying an on-skin sensor assembly to a skin of a host is provided. The applicator includes an applicator housing, a needle carrier assembly comprising an insertion element configured to insert a sensor of the on-skin sensor assembly into the skin of the host, a holder releasably coupled to the needle carrier assembly and configured to guide the on-skin sensor assembly while coupled to the needle carrier assembly, and a drive assembly configured to drive the insertion element from a proximal starting position to a distal insertion position, and from the distal insertion position to a proximal retraction position.
    Type: Application
    Filed: June 22, 2018
    Publication date: December 27, 2018
    Inventors: John Michael Gray, Jennifer Blackwell, Paul V. Neale, Justen Deering England, Andrew Joncich, Cameron Brock, Peter C. Simpson, Thomas Metzmaker, Neel Narayan Shah, Mark Douglas Kempkey, Patrick John Castagna, Warren Terry, Jason Halac, Christian Michael Andre George, Daniel E. Apacible, John Charles Barry, Maria Noel Brown Wells, Kenneth Pirondini, Andrew Michael Reinhardt, Jason C. Wong, Remy E. Gagnon, David DeRenzy, Randall Scott Koplin, Alan Baldwin, Young Woo Lee, David A. Keller, Louise Emma van den Heuvel, Carol Wood Sutherland
  • Publication number: 20180363126
    Abstract: Various examples related to fabrication of thermally stable ultra-high density particle-in-cavity (PIC) nanostructures. In one example, a method includes disposing an anodized aluminum oxide (AAO) template onto a surface of a substrate; removing, from the AAO template, a support layer disposed on a side of the AAO template opposite the surface of the substrate; etching nanocavities into the surface of the substrate using the AAO template as an etch mask; and removing the AAO template from the surface of the substrate. The method can include fabricating the AAO template on an aluminum substrate by anodization of an aluminum film and removing the AAO template from the aluminum substrate after formation of the support layer on the AAO template.
    Type: Application
    Filed: December 2, 2016
    Publication date: December 20, 2018
    Inventors: Cheng Xu, Luping Li, Yang Zhao, Kirk Jeremy Ziegler, Justin C. Wong
  • Patent number: 10150805
    Abstract: The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor ?/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus).
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: December 11, 2018
    Assignee: Altor Bioscience, LLC
    Inventors: Hing C. Wong, Peter Rhode, Bai Liu, Xiaoyun Zhu, Kai-Ping Han
  • Patent number: 10135779
    Abstract: Techniques and systems are described to determine levels of competency of users as part of an online community and control generation of subsequent digital content to be used interaction of the online community with the users based on this determination. In one example, determination of the level of competency is based on relevance to topics of the online community. In another example, a determination is made as to whether the topic of the online community is stable before using user competency scores to control generation of subsequent digital content. In a further example, users of the online community are identified as exhibiting dormant or non-dormant behavior and used as a basis to control generation of subsequent digital content. In yet another example, user competency scores are adjusted based on a decay factor to address dormancy of users over a period of time.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: November 20, 2018
    Assignee: Adobe Systems Incorporated
    Inventors: Niyati Chhaya, Laurie M. Byrum, Harsh Jhamtani, Calvin K. C. Wong
  • Patent number: 10120924
    Abstract: A data storage system with quorum-based commits sometimes experiences replica failure, due to unavailability of a replica-hosting node, for example. Described herein are methods and systems for improving data persistence and availability in a distributed data store where data is stored in a plurality of shards and a given shard is replicated across a plurality of nodes so as to create a plurality of replicas, and a quorum of replicas is needed for access to the given shard. Among other things, the methods and systems generally involve determining whether to quarantine or delete unavailable replicas in a given shard, and how to handle purge requests related to the shard when there are quarantined replicas.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: November 6, 2018
    Assignee: AKAMAI TECHNOLOGIES, INC.
    Inventors: Kai C Wong, Philip A Lisiecki, Sung Chiu
  • Publication number: 20180305376
    Abstract: The present invention provides thiazole compounds of Formula I wherein W, Y, R0, R2, R4, R5, R6, R7, X1, X2, X3 and X4 are as defined herein, or a stereoisomer, tautomer, pharmaceutically acceptable salt, prodrug ester or solvate form thereof, wherein all of the variables are as defined herein. These compounds are inhibitors of platelet aggregation and thus can be used as medicaments for treating or preventing thromboembolic disorders.
    Type: Application
    Filed: June 27, 2018
    Publication date: October 25, 2018
    Inventors: Jacques Banville, Roger Remillard, Edward H. Ruediger, Daniel H. Deon, Marc Gagnon, Laurence Dube, Julia Guy, Eldon Scott Priestley, Shoshana L. Posy, Brad D. Maxwell, Pancras C. Wong, R. Michael Lawrence, Michael M. Miller
  • Publication number: 20180298839
    Abstract: A method to detect and mitigate sensor or actuator degradation in an automobile system includes: collecting a signal data output from at least one device which is outputting the signal data in response to monitored operational parameters of a motor vehicle system; analyzing patterns of the signal data compared to a signal data output from a nominal operating one of the at least one device using an artificial intelligence program; and identifying when the patterns of the signal data exceed a threshold level indicating the at least one sensor or actuator is operating in a degraded condition.
    Type: Application
    Filed: April 12, 2017
    Publication date: October 18, 2018
    Inventors: Kevin C. Wong, Jeffrey M. Hutmacher, Marcus S. Gilbert
  • Publication number: 20180291832
    Abstract: A method to detect and mitigate sensor degradation in an automobile system includes: collecting output signal data from at least one of a sensor and an actuator which is outputting the signal data related to operational parameters of a vehicle system; placing the sensor or the actuator in communication with a fault box used to purposely corrupt the output signal data; analyzing patterns of the output signal data compared to signal data from a nominal operating sensor or actuator using an artificial intelligence program; identifying when a statistical range of the patterns exceeds a first threshold level; and modifying a control signal to change the operational parameters of the vehicle system.
    Type: Application
    Filed: April 5, 2017
    Publication date: October 11, 2018
    Inventors: Christopher E. Whitney, Kevin C. Wong, Marcus S. Gilbert, Jeffrey M. Hutmacher
  • Publication number: 20180293814
    Abstract: A method to determine a status of a motor vehicle includes collecting a first output signal data from at least one device which is outputting the signal data related to a first plurality of operational parameters and a first plurality of environmental parameters of the motor vehicle. The method further includes identifying patterns within the first output signal data, analyzing the patterns within the first output signal data; and generating a second output signal data defining a second plurality of operational parameters distinct from the first operational parameters.
    Type: Application
    Filed: April 5, 2017
    Publication date: October 11, 2018
    Inventors: Marcus S. Gilbert, Kevin C. Wong
  • Patent number: 10096521
    Abstract: A double sidewall image transfer process for forming FinFET structures having a fin pitch of less than 40 nm generates paired fins with a spacing determined by the width of a sidewall spacer that forms a second mandrel. Here, the fin pairs are created at two different spacings without requiring the minimum space for the standard sidewall structure. An enlarged space between paired fins is created by placing two first mandrel shapes close enough so as to overlap or merge two sidewall spacer shapes so as to form a wider second mandrel upon further processing. The fin pair created from the wider second mandrel is spaced at about 2 times the fin pair created from the narrower second mandrel. For some circuits, such as an SRAM bitcell, the wider second mandrel can be utilized to form an inactive fin not utilized in the circuit structure, which can be removed. In some embodiments, all dummy inactive fins are eliminated for a simpler process.
    Type: Grant
    Filed: January 3, 2017
    Date of Patent: October 9, 2018
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Mary E. Weybright, Robert C. Wong