Abstract: An input-output circuit is coupled to a plurality of serial communication paths and to a physical point-to-point interface. The input-output circuit is configured to transmit data received on the plurality of serial communication paths over the physical point-to-point interface. An application circuit is coupled to the input-output circuit and is configured to communicate via a first one of the paths in performing application functions. A bridge circuit is coupled to the input-output circuit and is configured to communicate via a second one of the paths. A debug circuit is coupled to the application circuit and to the bridge circuit. The debug circuit is configured to capture debug data of the application circuit and provide the debug data to the bridge circuit for communication via the second one of the paths.

Abstract: An apparatus and associated methods of use for a controlled combination of reagents is disclosed. The apparatus includes a vessel 400, a vessel insert 220, and a cap element 200. The vessel 400 has a body portion 410 for receiving a biological sample. The vessel insert 220 receives at least one reagent therein. Preferably, the vessel insert 220 is received in a portion 420 of the vessel 400. The cap element 200 is attached to the vessel 400 to secure the vessel insert 220 in the vessel 400. During use, the vessel insert 220 is adapted to release its contents when the biological sample is introduced into the body portion 410 of the vessel 400 upon application of an intermixing force to the vessel insert 220. A variety of intermixing forces may be applied, depending upon the embodiment of the present invention and its associated methods of use.

Abstract: An apparatus for detecting a disease in a biological subject comprises a delivery system and at least two sub-equipment units which are combined or integrated in the apparatus, wherein the delivery system is capable of delivering the biological subject to at least one of the sub-equipment units and each sub-equipment unit is capable of detecting at least one property of the biological subject. Methods for detecting a disease with the apparatus are also provided.

Abstract: Managing a virtual object in a server device includes storing the virtual object in a database accessible to the server device and, in response to a non-subscriber user performing a first action on the virtual object, sending a message from the server device to at least one user that subscribes to the virtual object.

Abstract: An apparatus and associated methods of use for a controlled combination of reagents is disclosed. The apparatus includes a vessel 400, a vessel insert 220, and a cap element 200. The vessel 400 has a body portion 410 for receiving a biological sample. The vessel insert 220 receives at least one reagent therein. Preferably, the vessel insert 220 is received in a portion 420 of the vessel 400. The cap element 200 is attached to the vessel 400 to secure the vessel insert 220 in the vessel 400. During use, the vessel insert 220 is adapted to release its contents when the biological sample is introduced into the body portion 410 of the vessel 400 upon application of an intermixing force to the vessel insert 220. A variety of intermixing forces may be applied, depending upon the embodiment of the present invention and its associated methods of use.

Abstract: The invention relates to apparatus and methods for apparatus for detecting presence or monitoring profession of a disease in a biological subject, comprising a chamber in which the biological subject passes through, and at least one detection transducer placed partially or completely in the chamber; wherein information related to properties of cells in the biological subject and of cell-surrounding media is detected by the detection transducer and collected for analysis to determine whether the disease is likely to be present with the biological subject or to determine the status of the disease, thereby providing the ability to continuously determine or monitor progression of the disease.

Abstract: The invention provides decomposing apparatus which comprises a first sub-component and a first micro device comprising a decomposable material, wherein the sub-component comprises a drug, a medical kit, a micro-disease detection system, or an auto-navigation system. Also within the invention are methods for fabricating such apparatus.

Abstract: The present invention provides moldable, fully scalable cellulose silica-based hydrogels for use as low-cost and safe carriers and aqueous viscosity modifiers in various industrial and medical applications.

Abstract: The present invention provides moldable, fully scalable cellulose silica-based hydrogels for use as low-cost and safe carriers and aqueous viscosity modifiers in various industrial and medical applications.

Abstract: Among others, the present invention provides apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.

Abstract: Local terrain feature location data is obtained from a local sensor device at a user location without a prior-known global position. The local terrain feature location data characterizes relative distances and directions to a plurality of local terrain features nearest to the user location. Global terrain feature location data stored in at least one hardware memory device is accessed. The global terrain feature location data characterizes relative distances and directions between a plurality of distinctive terrain features located in a defined terrain region in terms of absolute global location coordinates. The local terrain feature location data is compared to the global terrain feature location data to develop multiple pattern matching hypotheses, wherein each pattern matching hypothesis characterizes a likelihood of a subset of the local terrain features matching a subset the global terrain features. Global location coordinates for the user location is then determined from the pattern matching hypotheses.

Abstract: Tight spots in movements of a drill string in an oil well are identified by comparing a large interval hookload moving average to a short interval hookload moving average, comparing a large interval bit depth moving average to a short interval bit depth moving average, and DBSCANing the tight spots to identify a fully-stuck event.

Abstract: Among others, the present invention provides apparatus comprising two micro-devices each fabricated by the method comprising: the first step of depositing a first material onto a substrate; the second step of depositing a second material onto the first material and then patterning the second material with a microelectronic technology or process; and repeating the second step at least once with a material that can be the same as or different from the first or second material. The micro-devices can pierce through the membrane of a circulating tumor cell and can move in different direction.

Abstract: Among others, the present invention provides devices each including a micro-filter, a shutter, a cell counter, a selector, a micro-surgical kit, a timer, and a data processing circuitry, wherein the micro-filter is capable of detecting or filtering circulating tumor cells.

Abstract: Systems and methods may identify at least a first set of right singular vectors and a first set of singular values of a subset of the matrix, reduce the subset by an amount of energy of a selected data entry of the subset based on the first set of right singular vectors and the first set of singular values, incorporate a new data entry from the matrix into the subset, update the first set of right singular vectors and the first set of singular values of the subset based on the new data entry by a singular value decomposition (SVD) update, and generate the low-rank approximation of the matrix based on the updated first set of right singular vectors and the updated first set of singular values.

Abstract: Among others, the present invention provides devices each including a micro-filter, a shutter, a cell counter, a selector, a micro-surgical kit, a timer, and a data processing circuitry, wherein the micro-filter is capable of detecting or filtering circulating tumor cells.

Abstract: An apparatus for optimizing network traffic which includes a host computer having virtual machines (VMs); a monitoring module to collect network traffic data from the VMs; an analysis engine to receive the network traffic data from the monitoring module and to calculate metric values pertaining to the network traffic data; a pattern module to store network traffic patterns having metric values and to provide the network traffic patterns to the analysis engine, the analysis engine compares the calculated metric values to the network traffic pattern metric values and provides an output of a result of the compare of the calculated metric values to the network pattern metric values; and responsive to receipt of the output from the analysis engine, an optimization module processes the output and provides an optimization action to the VMs to improve the flow of the network traffic between the VMs.

Abstract: Among others, the present invention provides apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.

Abstract: Among others, the present invention provides apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.

Abstract: Among others, the present invention provides apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.