Abstract: An apparatus for detecting a disease in a biological subject comprises a delivery system and at least two sub-equipment units which are combined or integrated in the apparatus, wherein the delivery system is capable of delivering the biological subject to at least one of the sub-equipment units and each sub-equipment unit is capable of detecting at least one property of the biological subject. Methods for detecting a disease with the apparatus are also provided.

Abstract: A method for providing personalized healthcare for a patient is provided. The method may include receiving information indicative of a patient, retrieving a record associated with the patient, receiving a query identifying a healthcare related issue associated with the patient, performing analytics via a statistical discovery component and a natural language processing component configured to interface with respective portions of heterogeneous data sources to selectively identify correlations between genomic profile information of the patient and selected data of the data sources, applying a selected risk model based on the query; and providing a response to the query including information associated with clinical decision support tailored to an identity of the user, the user being a selected one of a patient, a researcher and a clinician.

Abstract: A current detection circuit for detecting a current in a SMPS which has a first switch and a second switch; a current sensing circuit sensing a second switch current flowing through the second switch and providing a current sensing signal; and a current emulation circuit which generates a first current according to the current sensing signal and generate a second current according to the first current source, and the current emulation circuit further providing a current emulation signal based on the first current source and the second current source; wherein a current detection signal during a first period is proportional to the current emulation signal, and the current detection signal during a second period is proportional to the current sensing signal.

Abstract: A current detection circuit for detecting a current in a SMPS which has a first switch and a second switch; a current sensing circuit sensing a second switch current flowing through the second switch and providing a current sensing signal; and a current emulation circuit which generates a first current according to the current sensing signal and generate a second current according to the first current source, and the current emulation circuit further providing a current emulation signal based on the first current source and the second current source; wherein a current detection signal during a first period is proportional to the current emulation signal, and the current detection signal during a second period is proportional to the current sensing signal.

Abstract: User-authored notes on shared documents may be provided. A shared document may be stored and at least one note may be associated with the document. When a user displays the document, the associated not may be retrieved and a user interface element may be provided to allow the user to view the note.

Abstract: Compositions and methods for the rapid and sensitive detection of a carbapenemase in a sample are provided. The compositions include novel primer and probe compositions for use in detecting the presence of this enzyme in a sample, particularly using PCR methods. These primers and probe sets can be used in amplification methods (such as PCR, particularly quantitative PCR) and packaged into kits for use in amplification methods for the purpose of detecting carbapenemase in a test sample, particularly a patient sample, particularly a direct sample. Thus, in one embodiment, the present invention provides for novel oligonucleotide primers set forth in SEQ ID NOs:1, 2, 4, 5, 7, 8, 14, 15, 17, 18, and 20, and the novel oligonucleotide probe sequences set forth in SEQ ID NOs:3, 6, 9, 16, and 19. These sequences can be used in a method of detecting carbapenemase in a sample.

Abstract: A method and apparatus for estimating and compensating for a broad class of non-Gaussian sensor and process noise. In one example, a coded filter combines a dynamic state estimator (for example, a Kalman filter) and a non-linear estimator to provide approximations of the non-Gaussian process and sensor noise associated with a dynamic system. These approximations are used by the dynamic state estimator to correct sensor measurements or to alter the dynamic model governing evolution of the system state. Examples of coded filters leverage compressive sensing techniques in combination with error models based on concepts of compressibility and the application of efficient convex optimization processes.

Abstract: A pixel array including circuitry for combining charges accumulated by individual pixels in the array enables addition and/or subtraction of individual pixel values, prior to their digitization, in the pixel array.

Abstract: In general, the subject matter described in this specification can be embodied in methods, systems, and program products for adaptive data unit transmission. A sliding window is filled with data units and designates a sliding window start position and a sliding window end position. A value for each of the data units in the sliding window is stored, the value representing a maximum number of times that each data unit is to be transmitted. The stored value is different among at least two of the data units. Data units are selected from the sliding window to be assembled into a packet. An assembled packet is transmitted to a receiving computerized device. A determination that the data unit positioned at the sliding window start position has been transmitted a maximum number of time is performed, and in response a different data unit is positioned at the sliding window start position.

Abstract: The present invention provides, among others, apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.

Abstract: The present invention relates to isocyanate functional prepolymers, aqueous polyurethane dispersions produced from the prepolymers and various uses of such dispersions. The prepolymers are prepared by reacting a diisocyanate, a dihydroxy compound having a number average molecular weight of from about 700 to about 16,000, and a trihydroxy component of the formula: R—(OH)3 where R is a saturated straight chain or branched chain aliphatic group of from 2 to 8 carbon atoms. The invention also relates to polyurethane dispersions prepared from the prepolymers and to various uses of the resultant dispersions.

Abstract: A learning health system and associated methods are provided. Biochemical assays are conducted at scheduled intervals on blood samples taken from an individual to provide, for each of a plurality of biochemical parameters, a time series of values representing the individual. Clinical parameters associated with the individual are extracted from a knowledge base. Genomic parameters are determined for the individual. An expected time series is calculated for each of a plural subset of the plurality of biochemical parameters from at least the clinical parameters and the genomic parameters. For each of the plural subset of biochemical parameters, the time series of values representing the individual is compared to the calculated expected time series to determine a likelihood of each of a plurality of conditions for the individual. The likelihood of at least one of the plurality of conditions is communicated to a user.

Abstract: Embodiments of the invention improve the quality of search results returned for a given set of search terms based on metadata associated with the user performing the search. A search query may specify metadata elements to consider in ranking the search results. The metadata used may include bookmarks set by the user (either locally or at a social bookmaking site), group bookmarks, etc. In such a case, search results may be reordered to improve the ranking of websites that are both in the search results and in the bookmarks.

Abstract: A system and a method for handling a system failure are disclosed. The method is adapted for an information handling system having a basic input and output system and a micro-controller. The method includes the following steps: sending, via the micro-controller, a signal; checking, via the micro-controller, whether an acknowledgement is received from the basic input and output system responsive to the signal; and scanning, via the micro-controller, a type of a system failure in response to the acknowledgement being not received.

Abstract: A method may include identifying a repeating frame structure for communication between a MIMO base station and one or more wireless devices, the frame structure including a plurality of slots, with each slot including an uplink portion and a downlink portion, and each uplink portion and downlink portion comprising a plurality of sub-slots, receiving, at the wireless base station, an identification of a first wireless device of the one or more wireless devices, assigning to the first wireless device, a sub-slot in an uplink portion of a static slot in the frame structure, communicating, to the first wireless device, information from which the first wireless device can identify the sub-slot, and communicating with the one or more wireless devices by associating data in the first sub-slot with the first wireless device.

Abstract: A system and a method for handling a system failure are disclosed. The method is adapted for an information handling system having a basic input and output system and a micro-controller. The method includes the following steps: sending, via the micro-controller, a signal; checking, via the micro-controller, whether an acknowledgement is received from the basic input and output system responsive to the signal; and scanning, via the micro-controller, a type of a system failure in response to the acknowledgement being not received.

Abstract: Among others, the present invention provides apparatus for detecting circulating tumor cells, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electrical, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, electro-mechanical, electro-chemical, electro-optical, electro-thermal, electro-chemical-mechanical, bio-chemical, bio-mechanical, bio-optical, bio-thermal, bio-physical, bio-electro-mechanical, bio-electro chemical, bio-electro-optical, bio-electro-thermal, bio-mechanical-optical, bio-mechanical thermal, bio-thermal-optical, bio-electro-chemical-optical, bio-electro-mechanical-optical, bio electro-thermal-optical, bio-electro-chemical-mechanical, physical or mechanical property, or a combination th

Abstract: Among others, the present invention provides devices each including a micro-filter, a shutter, a cell counter, a selector, a micro-surgical kit, a timer, and a data processing circuitry, wherein the micro-filter is capable of detecting or filtering circulating tumor cells.

Abstract: Among others, the present invention provides apparatus for detecting circulating tumor cells, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electrical, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, electro-mechanical, electro-chemical, electro-optical, electro-thermal, electro-chemical-mechanical, bio-chemical, bio-mechanical, bio-optical, bio-thermal, bio-physical, bio-electro-mechanical, bio-electro-chemical, bio-electro-optical, bio-electro-thermal, bio-mechanical-optical, bio-mechanical thermal, bio-thermal-optical, bio-electro-chemical-optical, bio-electro-mechanical-optical, bio-electro-thermal-optical, bio-electro-chemical-mechanical, physical or mechanical property, or a combination th

Abstract: The present invention provides compositions and methods related to the production of fatty acids, such as triglycerides with genetically engineered cells, such as algae.