Abstract: Among others, the present invention provides micro-devices for detecting or treating a disease, each comprising a first sorting unit capable of detecting a property of the biological subject at the microscopic level and sorting the biological subject by the detected property; a first detection unit capable of detecting the same or different property of the sorted biological subject at the microscopic level; and a first layer of material having an exterior surface and an interior surface, wherein the interior surface defines a first channel in which the biological subject flows from the first sorting unit to the first detection unit.

Abstract: Among others, the present invention provides devices each including a micro-filter, a shutter, a cell counter, a selector, a micro-surgical kit, a timer, and a data processing circuitry, wherein the micro-filter is capable of detecting or filtering circulating tumor cells.

Abstract: Among others, the present invention provides devices each including a micro-filter, a shutter, a cell counter, a selector, a micro-surgical kit, a timer, and a data processing circuitry, wherein the micro-filter is capable of detecting or filtering circulating tumor cells.

Abstract: Methods and apparatuses for compressive sensing that enable efficient recovery of features in an input signal based on acquiring a few measurements corresponding to the input signal. One method of compressive sensing includes folding an image to generate first and second folds, and recovering a feature of the image based on the first and second folds without reconstructing the image. One example of a compressive sensing apparatus includes a lens, a focal plane array coupled to the lens and configured to generate first and second folds based on the image, and a decoder configured to receive the first and second folds and to recover a feature of the image without reconstructing the image. The feature may be a local geometric feature or a corner. Compressive sensing methods and apparatuses for determining translation and rotation between two images are also disclosed.

Abstract: Among others, the present invention provides devices each including a micro-filter, a shutter, a cell counter, a selector, a micro-surgical kit, a timer, and a data processing circuitry, wherein the micro-filter is capable of detecting or filtering circulating tumor cells.

Abstract: Among others, the present invention provides apparatus for interacting with a biological subject to detect circulating tumor cells therein, comprising one device for sending a signal to the biological subject and optionally receiving a response to the signal from the biological entity.

Abstract: An example method includes receiving a data set containing combinations of drilling parameter values and operating condition values for a drilling system corresponding to each combination of drilling parameter values. At least one of a frequency and a duration of use may be determined for each of the combinations of drilling parameter values in the data set. For at least some of the combinations of drilling parameter values, a contour map identifying the combinations of drilling parameter values, the operating condition values corresponding to the combinations of drilling parameter values, and at least one of the frequency and the duration of use may be displayed for at least some of the combinations of drilling parameter values.

Abstract: The present invention discloses a random access memory and the memory access method thereof capable of avoiding read disturbance and increasing reading speed. An embodiment of the said random access memory comprises: a word line; a word line driving unit, coupled to the word line, operable to receive an access control signal to generate a word line enablement voltage; a voltage adjusting unit including a switch and a capacitor in which the switch is coupled to the word line and operable to receive a control signal to determine a conduction state of the switch itself and the capacitor is coupled to the switch and operable to adjust a voltage level of the word line enablement voltage according to the conduction state; and a memory unit, coupled to the word line, operable to be enabled according to the word line enablement voltage.

Abstract: A learning health system and associated methods are provided. Biochemical assays are conducted at scheduled intervals on blood samples taken from an individual to provide, for each of a plurality of biochemical parameters, a time series of values representing the individual. Clinical parameters associated with the individual are extracted from a knowledge base. Genomic parameters are determined for the individual. An expected time series is calculated for each of a plural subset of the plurality of biochemical parameters from at least the clinical parameters and the genomic parameters. For each of the plural subset of biochemical parameters, the time series of values representing the individual is compared to the calculated expected time series to determine a likelihood of each of a plurality of conditions for the individual. The likelihood of at least one of the plurality of conditions is communicated to a user.

Abstract: Tight spots in movements of a drill string in an oil well are identified by comparing a large interval hookload moving average to a short interval hookload moving average, comparing a large interval bit depth moving average to a short interval bit depth moving average, and DBSCANing the tight spots to identify a fully-stuck event.

Abstract: The present invention provides methods and apparatus for enhanced detection of a disease by among others enhancing the difference in a microscopic property of diseased cells and normal cells, thereby enhancing the detection sensitivity and specificity.

Abstract: A method may include identifying a repeating frame structure for communication between a MIMO base station and one or more wireless devices, the frame structure including a plurality of slots, with each slot including an uplink portion and a downlink portion, and each uplink portion and downlink portion comprising a plurality of sub-slots, receiving, at the wireless base station, an identification of a first wireless device of the one or more wireless devices, assigning to the first wireless device, a sub-slot in an uplink portion of a static slot in the frame structure, communicating, to the first wireless device, information from which the first wireless device can identify the sub-slot, and communicating with the one or more wireless devices by associating data in the first sub-slot with the first wireless device.

Abstract: An apparatus and associated methods of use for a controlled combination of reagents is disclosed. The apparatus includes a vessel 400, a vessel insert 220, and a cap element 200. The vessel 400 has a body portion 410 for receiving a biological sample. The vessel insert 220 receives at least one reagent therein. Preferably, the vessel insert 220 is received in a portion 420 of the vessel 400. The cap element 200 is attached to the vessel 400 to secure the vessel insert 220 in the vessel 400. During use, the vessel insert 220 is adapted to release its contents when the biological sample is introduced into the body portion 410 of the vessel 400 upon application of an intermixing force to the vessel insert 220. A variety of intermixing forces may be applied, depending upon the embodiment of the present invention and its associated methods of use.

Abstract: A SRAM module and a writing control method of the SRAM module are disclosed. The writing control method of the SRAM module is applied to a SRAM module that includes a plurality of memory cells and a bit line. The method includes: providing a first voltage as a supply voltage of the plurality of memory cells during a data retention time; decreasing a first voltage level corresponding to the data retention time of the memory cells to a second voltage level by discharging the memory cells; and performing a write process to the memory cells through the bit line. The discharge time from the first voltage level to the second voltage level is related to the number of the memory cells.

Abstract: The present invention discloses a random access memory and the memory access method thereof capable of avoiding read disturbance and increasing reading speed. An embodiment of the said random access memory comprises: a word line; a word line driving unit, coupled to the word line, operable to receive an access control signal to generate a word line enablement voltage; a voltage adjusting unit including a switch and a capacitor in which the switch is coupled to the word line and operable to receive a control signal to determine a conduction state of the switch itself and the capacitor is coupled to the switch and operable to adjust a voltage level of the word line enablement voltage according to the conduction state; and a memory unit, coupled to the word line, operable to be enabled according to the word line enablement voltage.

Abstract: Among others, the present invention provides apparatus for detecting circulating tumor cells, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electrical, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, electro-mechanical, electro-chemical, electro-optical, electro-thermal, electro-chemical-mechanical, bio-chemical, bio-mechanical, bio-optical, bio-thermal, bio-physical, bio-electro-mechanical, bio-electro-chemical, bio-electro-optical, bio-electro-thermal, bio-mechanical-optical, bio-mechanical thermal, bio-thermal-optical, bio-electro-chemical-optical, bio-electro-mechanical-optical, bio-electro-thermal-optical, bio-electro-chemical-mechanical, physical or mechanical property, or a combination th

Abstract: Methods and apparatuses for compressive sensing that enable efficient recovery of features in an input signal based on acquiring a few measurements corresponding to the input signal. One method of compressive sensing includes folding an image to generate first and second folds, and recovering a feature of the image based on the first and second folds without reconstructing the image. One example of a compressive sensing apparatus includes a lens, a focal plane array coupled to the lens and configured to generate first and second folds based on the image, and a decoder configured to receive the first and second folds and to recover a feature of the image without reconstructing the image. The feature may be a local geometric feature or a corner. Compressive sensing methods and apparatuses for determining translation and rotation between two images are also disclosed.

Abstract: A server device includes a processor; and a memory communicatively coupled to the processor. The memory includes executable code that causes the processor, upon execution of the executable code, to: maintain a database comprising a virtual object; maintain a database of users that subscribe to the virtual object; and in response to receiving a request from a non-subscriber user to perform a first action on the virtual object, send a message to at least one of the users that subscribe to the virtual object.

Abstract: In general, the subject matter described in this specification can be embodied in methods, systems, and program products for adaptive data unit transmission. A sliding window is filled with data units and designates a sliding window start position and a sliding window end position. A value for each of the data units in the sliding window is stored, the value representing a maximum number of times that each data unit is to be transmitted. The stored value is different among at least two of the data units. Data units are selected from the sliding window to be assembled into a packet. An assembled packet is transmitted to a receiving computerized device. A determination that the data unit positioned at the sliding window start position has been transmitted a maximum number of time is performed, and in response a different data unit is positioned at the sliding window start position.

Abstract: Systems and methods for generating a low-rank approximation of a matrix are provided. The various systems and methods may identify at least a first set of right singular vectors and a first set of singular values of a subset of the matrix, reduce the subset by an amount of energy of a selected data entry of the subset based on the first set of right singular vectors and the first set of singular values, incorporate a new data entry from the matrix into the subset, update the first set of right singular vectors and the first set of singular values of the subset based on the new data entry by a singular value decomposition (SVD) update, and generate the low-rank approximation of the matrix based on the updated first set of right singular vectors and the updated first set of singular values.