Abstract: Provided is a tetanus toxin protein variant, the tetanus toxin protein variant comprising a C fragment of the tetanus toxin protein and a partial fragment of a translocation region of the tetanus toxin protein. Further provided is a proteoglycan conjugate, the proteoglycan conjugate comprising a polysaccharide from Streptococcus pneumoniae and a truncated tetanus toxin protein. Also provided is a method for improving immunogenicity, the method comprising the following steps: providing a proteoglycan conjugate comprising a polysaccharide from Streptococcus pneumoniae and a truncated tetanus toxin protein.

Abstract: The invention provides a power distribution and drive system for a remotely underwater operated vehicle ROV, comprises: a high-voltage DC power supply device, located above the water surface to provide high-voltage DC voltage to the ROV; a DC buck conversion device, connected to the high-voltage DC power supply device through a cable for converting the high-voltage DC voltage to a low-voltage DC voltage to supply power to the ROV, wherein the DC buck conversion device comprises multiple parallel DC conversion modules, each DC conversion module bearing an average load current to supply power to the ROV; and at least one thruster, which comprises a propeller, a synchronous motor, and a driver.

Abstract: A method for processing a fluid sample containing a first target analyte includes introducing a first batch of magnetic particles into a fluid conduit, the fluid conduit having a first open end, a second open end, and a first electromagnetic trap between the first open end and the second open end. The magnetic particles include a first receptor to bind the first target analyte in the fluid sample. The method further includes activating the first electromagnetic trap to trap and mix the magnetic particles within the first electromagnetic trap. A flow of the fluid sample is introduced through the fluid conduit from the first open end to the second open end. Deactivating first electromagnetic trap releases the magnetic particles from the first electromagnetic trap.

Abstract: Provided are a data processing method and apparatus, a device, and a storage medium, which relate to the technical field of cloud computing and cloud platform. The specific implementation scheme includes: determining, according to logic information of first data acquired from an ordering tool, first physical addresses, where the first physical addresses are physical addresses of data shards in a physical data group associated with the first data; and sending the first physical addresses to the ordering tool to cause the ordering tool to order the first data according to the first physical addresses.

Abstract: The embodiments of the present application provide an instruction retirement unit, an instruction execution unit, and a related apparatus and method. The instruction retirement unit includes: a reception subunit, configured to receive a completion request signal; an arbitration subunit, configured to send a completion permission signal to an instruction execution unit after determining that instructions to be completed can be completed, and store instruction completion information of the instructions to be completed into instruction buffer table entries in a buffer; and a retirement subunit, configured to perform, based on the instruction completion information stored in each of the instruction buffer table entries, retirement processing on instructions that have already been completed and have not been retired, and delete the instruction completion information of retired instructions from the instruction buffer table entries.

Abstract: A computing system is provided, including a processor configured to, during a training phase, provide a training data set including a pre-transformation molecular graph and post-transformation energy parameter value representing an energy change in a molecular system following an energy transformation. The pre-transformation molecular graph includes a plurality of normal nodes fully connected by edges. The processor is configured to encode structural information including a three-dimensional Euclidean distance along an edge connecting a pair of the normal nodes in each molecular graph as learnable embeddings. The processor is configured to input the training data set to a transformer-based graph neural network to train the network to perform an inference at inference time.

Abstract: A camera invocation method includes preview interfaces corresponding to a plurality of applications in an electronic device that simultaneously display an image captured in real time by a camera of the electronic device, where the applications share the camera.

Abstract: The embodiments of the present application provide a processing unit. The processing unit comprises: an instruction fetching unit configured for fusing instruction of vector configuration instruction and vector operation instruction that are adjacent in order to obtain fusion instruction; an instruction decoding unit configured to decode the fusion instruction to obtain first execution information and second execution information; a vector configuration unit configured to execute the vector configuration instruction according to the first execution information, modify vector control register, and bypass the value of the modified vector control register to the vector operation unit; the vector operation unit configured to execute the vector operation instruction according to the second execution information and the value of the modified vector control register.

Abstract: A system and method for accelerated anomaly detection and replacement of an anomaly-experiencing machine learning-based ensemble includes identifying a machine learning-based digital threat scoring ensemble having an anomalous drift behavior in digital threat score inferences computed by the machine learning-based digital threat scoring ensemble for a target period; executing a tiered anomaly evaluation for the machine learning-based digital threat scoring ensemble that includes identifying at least one errant machine learning-based model of the machine learning-based digital threat scoring ensemble contributing to the anomalous drift behavior, and identifying at least one errant feature variable of the at least one machine learning-based model contributing to the anomalous drift behavior; generating a successor machine learning-based digital threat scoring ensemble to the machine learning-based digital threat scoring ensemble based on the tiered anomaly evaluation; and replacing the machine learning-based di

Abstract: A terminal device includes a display unit, and an outer case, a first light sensing unit, and a second light sensing unit. The display unit has a display screen. The display unit displays images on the display screen. The outer case receives the display unit. The first light sensing unit is located below the display unit and configured to sense incident light transmitted through the display screen. The second light sensing unit is placed inside the outer case when deactivated, and extends outside the outer case when activated. Also, a dual front-facing camera operating method is provided.

Abstract: The present disclosure provides a semiconductor structure including a first electrode via, a first electrode on the first electrode via, a magnetic tunneling junction (MTJ) over the first electrode, a second electrode over the MTJ, a first dielectric layer on the first electrode via, a second dielectric layer on the first dielectric layer. The first dielectric layer is a planar layer. A sidewall of the MTJ is in contact with the second dielectric layer, and a bottom surface of the second dielectric layer is higher than a bottom surface of the first electrode.

Abstract: A virtual simulation method for a conveying mechanism includes obtaining a data model of the conveying mechanism, creating a virtual conveying line according to the data model so that the data model is movable along the virtual conveying line during a simulation process, creating a target logic block used to determine an actual distance for which the data model moves each time during the simulation process, and sending the actual distance to a PLC, so that when it is determined that the actual distance is the same as a target distance for which the conveying mechanism should move each time, the PLC controls the data model to stop moving.

Abstract: Disclosed herein are related to a device for performing neuromorphic computing. In one aspect, a device includes a back end of line layer including a three-dimensional memory array. The three-dimensional memory array may include a plurality of memory cells to store a plurality sets of weight values of a neural network model. In one aspect, the device includes a front end of line layer including a controller. The controller may apply one or more input voltages corresponding to an input to the neural network model to the three-dimensional memory array, and receive one or more output voltages from the three-dimensional memory array to perform computations of the neural network model.

Abstract: Methods and apparatus for processing fluids are described. In various aspects, a fluid processing system may include a magnetic assembly that includes a plurality of magnetic structures configured to generate a magnetic field gradient within a fluid container. The magnetic structures may be formed as a plurality of electromagnets configured to be individually actuated by a controller. Each of the electromagnets may generate a magnetic field within the fluid container. The electromagnets may be differentially actuated to create a magnetic field gradient within the fluid container to agitate, mix, or otherwise influence magnetic particles disposed within the fluid container. Activation of the electromagnets of an electromagnetic structure may generate a magnetic field gradient that influences magnetic particles in an x-y direction.

Abstract: Systems and methods for personalizing messages in a conversational chatbot are disclosed. An example method may include receiving clickstream event data corresponding to click events by users of an application, generating featurized clickstream data based at least in part on the received clickstream event data, determining one or more predicted intentions for a first user based at least in part on the featurized clickstream data, and generating one or more personalized messages for the first user based at least in part on the one or more predicted user intentions.

Abstract: The present disclosure belongs to the field of pharmaceutical preparations and relates to the design of a series of lipophilic derivatives by using wild-type penetrating peptide penetratin. These penetratin derivatives have a strong ability to penetrate the ocular tissues and do not cause ocular tissue toxicity. As ocular absorption enhancers, non-invasive routes could be used to achieve intraocular drug delivery and increase the ocular bioavailability of drugs. These penetratin derivatives and the ophthalmic drug delivery system constructed by them are used for eye drop administration, which could replace the intraocular injection with poor patients compliance, which greatly enhances the convenience and safety of the treatment of intraocular and fundus diseases.

Abstract: A framework that includes one or more feature extractors (models) and a cluster component for clustering is described herein. The framework supports (1) offline image-based unsupervised clustering that replaces time-consuming manual gating; (2) online image-based single cell sorting. During training, one or multiple cell image datasets with or without ground truth are used to train one or more feature extractors, which are based on a neural network including several convolutional layers. Once trained, the feature extractors are used to extract features of cell images for unsupervised cell clustering and sorting. In addition, additional datasets may be used to further refine the feature extractors after they have been trained.

Abstract: Depositing a side slab structure on a cladding layer before etching a supporting dielectric prevents tapering of a silicon waveguide during etching of the supporting dielectric and a substrate. For example, the side slab structure may be deposited over the silicon waveguide and the cladding layer after etching the cladding layer. As a result, when an electronic device is integrated ex situ on the substrate, wave intensity and/or total internal reflection is improved, which improves an efficiency of the electronic device.

Abstract: A memory device includes a first metal structure, a magnetic tunnel junction (MTJ) structure, a second metal structure, a first spacer, and a second spacer. The MTJ structure is over the first metal structure. The second metal structure is over the MTJ structure. The first spacer is over a first sidewall of the second metal structure. The second spacer is over a second sidewall of the second metal structure. The second spacer has a top surface higher than a top surface of the first spacer.