Abstract: This invention generally relates to pyrazolo pyrimidine derivatives useful as, inter alia, inhibitors of short chain dehydrogenase/reductase (SDR) family of NAD(P)(H) dependent oxido-reductases. More specifically, the invention relates to pyrazolo pyrimidine derivatives, including derivatives and analogs of SDR inhibitors, pharmaceutical compositions containing derivatives and analogs of SDR inhibitors, methods of making derivatives and analogs of SDR inhibitors and methods of use thereof.

Abstract: Compounds active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.

Abstract: In an approach to determining an air quality based on image, a computer performs a method, the method comprising: determining an image to be measured; determining an air quality model of at least one key area, the at least one key area including a key area associated with the image to be measured; acquiring a reference clear image corresponding to the image to be measured; and determining an air quality index to be measured based on an air quality related feature extracted from the image to be measured, the corresponding reference clear image, and the determined air quality model of the key area associated with the image to be measured.

Abstract: A method for recognizing a primitive in an image includes recognizing at least one primitive in the image to obtain at least one candidate shape of the at least one primitive, which at least one candidate shape has a respective confidence; determining whether the recognizing of the at least one primitive has a potential error based on the confidence; obtaining auxiliary information about the at least one primitive from a user in response to determining that the recognizing has the potential error; and re-recognizing the at least one primitive at least in part based on the auxiliary information.

Abstract: A method for recognizing a primitive in an image includes recognizing at least one primitive in the image to obtain at least one candidate shape of the at least one primitive, which at least one candidate shape has a respective confidence; determining whether the recognizing of the at least one primitive has a potential error based on the confidence; obtaining auxiliary information about the at least one primitive from a user in response to determining that the recognizing has the potential error; and re-recognizing the at least one primitive at least in part based on the auxiliary information.

Abstract: The present invention discloses a progress adjustment method and an electronic device, the progress adjustment method is applied to an electronic device including a display unit on which data contents corresponding to first data are output in a chronological order, the method comprising displaying a progress bar corresponding to the first data on the display unit, and unit progress of the progress bar being a first unit progress; when obtaining a first input operation, controlling switching of the data contents of the first data with the first unit progress according to the first input operation; obtaining a second sliding operation; and generating a first sub progress bar based on a current progress unit that includes a progress identifier on the progress bar according to the second sliding operation; unit progress of the first sub progress bar being a second unit progress.

Abstract: An epitaxial growth method for preventing auto-doping effect is presented. This method starts with the removal of impurities from the semiconductor substrate and the reaction chamber to be used. Then the semiconductor substrate is loaded in the cleaned reaction chamber to be pre-baked under vacuum conditions before the extraction of the dopant atoms desorbed from the surface of the semiconductor substrate. Next, under high temperature and low gas flow conditions, a first intrinsic epitaxial layer is formed on the surface of said semiconductor substrate. Following this, under low temperature and high gas flow conditions, a second epitaxial layer of required thickness is formed on the structural surface of the grown intrinsic epitaxial layer. Last, silicon wafer is unloaded after cooling. This method can prevent auto-doping effect during the epitaxial growth on semiconductor substrate and thus ensure the performance and enhance the reliability of the devices in peripheral circuit region.

Abstract: Biased users detection. The present invention includes a computer implemented method for detecting biased users and a corresponding apparatus, the computer implemented method including: obtaining comments on a given topic by standard users and users to be detected; calculating respectively scores in attribute dimensions for the given topic by the standard users and the users to be detected according to the comments on the given topic by the standard users and the users to be detected, so as to map respectively the standard users and the users to be detected into a multi-dimensional space formed by a plurality of attribute dimensions, wherein the attribute dimensions reflect aspects of the given topic; and determining whether the users to be detected are biased users according to the similarity of distribution of the users to be detected and that of the standard users in the multi-dimensional space.

Abstract: An electronic device may include a first controller associated with some channels of a digitizer having channels configured to receive a signal from a stylus, and with each channel having a direction. A second controller may be associated with channels of the digitizer not associated with the first controller. The first controller may scan for the signal at each channel associated with the first controller, and based on acquisition of the signal at a given channel associated with the first controller, calculate a property of the signal. The first controller may send the calculated property and the direction of the given channel to the second controller. The first controller and the second controller may scan for the signal at each channel having the direction of the given channel, at acquisition intervals based upon the calculated property.

Abstract: The present invention discloses a method and apparatus of determining air quality. The method comprising: determining at least one key area; acquiring a reference clear image, a training image under poor air quality and corresponding actual air quality index in at least one location of the key area; and training an air quality model of the key area based on feature extracted from the reference clear image and the training image and based on the actual air quality index. With the method and apparatus of the invention, air quality can be determined based on image.

Abstract: The present disclosure provides an electronic device, which includes a display module and a speaker, the speaker is placed on the back surface of the display module, and the device includes a mainboard component and a power panel component placed on the back surface of the display module; the speaker is placed below the mainboard component and the power panel component, the speaker includes a speaker body, an inverter tube, a first loudspeaker for producing mediant or bass, a second loudspeaker for producing mediant or treble, a sound producing surface of the first loudspeaker is placed on the surface of the speaker body back to the display module, and a sound producing surface of the second loudspeaker is placed on the lower surface of the speaker body.

Abstract: A bis (2-dialkylaminoethyl) ether synthesizing method is disclosed, which includes steps of: 1) synthesizing: wherein N,N-dialkylethanolamine, N,N-dialkylamine and ethyne are mixed at a mole ratio of 4:3:1-2:1:1 as a raw material; and the raw material, catalyst and solvent are added in a high-pressure clave for reaction in a sealed condition; a weight of catalyst accounts for 2.0%-10.5% of the total weight of the raw material; a reaction temperature is 50-120° C. and the reaction time is 3-7 hours; the clave is then opened after reaction and a filtrate is collected by filtering the reaction mixture; and 2) separating: wherein the filtrate obtained in the step 1) is rectified to obtain the bis (2-dialkylaminoethyl) ether as a product. The synthetic method of the bis (2-dialkylaminoethyl) ether in the present invention has many characteristics, such as simple process, high atomic economy, etc.

Abstract: A control unit is selected from a plurality of narrowband mobile stations also forming an ad-hoc network. The control unit is configured to control and manage a narrowband trunking operation via the ad-hoc network. The control unit receives a call request over a narrowband control channel from a first mobile station, assigns a pair of narrowband traffic channels for a call associated with the call request, chooses two mobile stations from the plurality of mobile stations to act as a narrowband repeater for the call, the pair including a respective receiver mobile station and a respective transmitter mobile station, informs the repeater mobile stations of the assignment and of the assigned traffic channels for the call, and grants the call request over the narrowband control channel. The grant includes an indication of the assigned traffic channels on which the repeater mobile stations can be located for the call.

Abstract: A method for adjusting a display effect and an electronic apparatus that includes a frame body, a fixing device, and a functional main body section. The functional main body section includes a display device disposed in the frame body. When a user views a first display content in the first display region in a first interactive mode, a light beam emitted by the display device is incident upon the user's eyes so that the user perceives a first perception picture. The display parameter of the display device is adjusted by obtaining the adjustment parameter for instructing to adjust the display effect of the first perception picture, and thereby generating the corresponding control signal, so that a current display effect of the first perception picture is different from a display effect of the first perception picture before the adjustment.

Abstract: A method and an apparatus for determining a location of a mobile device. The location of a mobile device is determined accurately according to information which includes call data records of the mobile device. By employing a partial ellipse integral model, two physical world factors are taken into consideration in reducing the location uncertainty in call data records. The factors include: spatiotemporal constraints of the device's movement in the physical world and the telecommunication cell area's geometry information, which increase the accuracy of determining the location of a mobile device.

Abstract: A method and an apparatus for generating data in a missing segment of a target time data sequence are disclosed. The method includes: determining whether there is a breakpoint in the missing segment; determining candidate values of the data in the missing segment; and generating values of the data in the missing segment by selectively using the candidate values of the data in the missing segment, according to whether there is the breakpoint in the missing segment. With the method and the apparatus, the data in the missing segment of the target time data sequence can be generated more accurately.

Abstract: A multilayer structure including (a) a fabric, (b) a polyurethane foam containing a plurality of cells defined therein, wherein the foam contains at least one surfactant, and (c) a skin layer, wherein the skin layer comprises a wetting agent and an acrylic polymer having a glass transition temperature of ?20 degree Celsius or less, and the foam resides between the fabric and the skin layer; and the process of preparing the multilayer structure.

Abstract: Methods and devices associated with a phase change memory include Schottky diodes operating as selectors having a low turn-on voltage, low sneak current and high switching speed. A method of forming a semiconductor device includes providing a semiconductor substrate having a diode array region and a peripheral device region, forming an N+ buried layer in the diode array region, forming a semiconductor epitaxial layer on the N+ buried layer, and forming deep trench isolations through the epitaxial layer and the N+ buried layer along a first direction. The method also includes forming shallow trench isolations in the diode array region and in the peripheral region along a second line direction. The method also includes forming an N? doped region between the deep and shallow trench isolations and forming a metal silicide on a surface of the N? doped region.

Abstract: Systems and techniques for providing a three-dimensional touch screen are described. Example systems include a touch screen manager that is configured to display a screen via a display device, such as by projecting on a wall or other surface a screen generated by a computing device, such as a desktop, laptop, or tablet computer. The manager is further configured to receive position information from a sensor that determines the positions of objects, such as the finger or hand of a user, within a three-dimensional space in front of the display surface. The manager then converts the received position information into user interface events, including gestures (e.g., pinch, swipe), mouse-type events (e.g., click, drag), or the like. The user interface events are provided to an application or other module executing on the computing device.

Abstract: Embodiments of the present invention provide a method and an apparatus for configuring a transmission mode, where the method includes: obtaining channel matrix information, where the channel matrix information is any one of the following: a precoding matrix indicator which most matches a current uplink channel matrix of a terminal, a current downlink precoding matrix indicator of the terminal, an uplink channel matrix of the terminal and the precoding matrix indicator which most matches the current uplink channel matrix of the terminal, and the uplink channel matrix of the terminal and the current downlink precoding matrix indicator of the terminal; determining performance of data transmission performed by adopting a closed-loop mode and an open-loop mode according to the channel matrix information, and selecting the data transmission mode according to the determined performance of data transmission, where the data transmission mode includes the open-loop mode, the closed-loop mode.