Abstract: The invention relates to novel 3,5-dichloro,4-(3,4-(cyclo-) alkoxyphenyl)-2-carbonyloxy)ethyl)pyridine compounds which are both inhibitors of the phosphodiesterase 4 (PDE4) enzyme and muscarinic M3 receptor antagonists, methods of preparing such compounds, compositions containing them and therapeutic use thereof.

Abstract: Compounds of formula (I) are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for the prevention and/or treatment of diseases of the respiratory tract characterized by airway obstruction.

Abstract: Compounds of formula (I), defined herein, are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for the prevention and/or treatment of a disease of the respiratory tract.

Abstract: Compounds of formula (I) are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for the prevention and/or treatment of diseases of the respiratory tract characterized by airway obstruction.

Abstract: Compounds of formula (I), defined herein, are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for the prevention and/or treatment of a disease of the respiratory tract.

Abstract: The invention relates to novel 3,5-dichloro,4-(3,4-(cyclo-) alkoxyphenyl)-2-carbonyloxy)ethyl)pyridine compounds which are inhibitors of the phosphodiesterase 4 (PDE4) enzyme and muscarinic M3 receptor antagonists, methods of preparing such compounds, compositions containing them and therapeutic use thereof.

Abstract: Embodiments of the invention provide an apparatus for mounting an interactive/flat panel display device to a wall. According to at least one embodiment, the apparatus includes a first vertical member including a first portion and a second portion. The first portion is at least partially inserted into the second portion. One distal end of the first portion is attached to a first plate and one distal end of the second portion is attached to a second plate. The apparatus further includes a second vertical member including a third portion and a fourth portion. The third portion is at least partially inserted into the fourth portion. One distal end of the third portion is attached to a third plate and one distal end of the fourth portion is attached to a fourth plate. The apparatus further includes a first set of brackets configured to attach the first plate and the third plate to one of a ceiling or a wall, and a second set of brackets configured to attach the second plate and the fourth plate to a flooring.

Abstract: The invention relates to novel 3,5-dichloro,4-(3,4-(cyclo-) alkoxyphenyl)-2-carbonyloxy)ethyl)pyridine compounds which are both inhibitors of the phosphodiesterase 4 (PDE4) enzyme and muscarinic M3 receptor antagonists, methods of preparing such compounds, compositions containing them and therapeutic use thereof.

Abstract: Compounds of formula (I) defined herein are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for treating diseases of the respiratory tract.

Abstract: Embodiments of the invention provide an apparatus for mounting an interactive/flat panel display device to a wall. According to at least one embodiment, the apparatus includes a first vertical member including a first portion and a second portion. The first portion is at least partially inserted into the second portion. One distal end of the first portion is attached to a first plate and one distal end of the second portion is attached to a second plate. The apparatus further includes a second vertical member including a third portion and a fourth portion. The third portion is at least partially inserted into the fourth portion. One distal end of the third portion is attached to a third plate and One distal end of the fourth portion is attached to a fourth plate. The apparatus further includes a first set of brackets configured to attach the first plate and the third plate to one of a ceiling or a wall, and a second set of brackets configured to attach the second plate and the fourth plate to a flooring.

Abstract: Compounds of formula (I) defined herein are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for treating diseases of the respiratory tract.

Abstract: Compounds of formula (I) defined herein are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for treating diseases of the respiratrory tract.

Abstract: Compounds of formula (I) defined herein are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for treating diseases of the respiratory tract.

Abstract: Compounds of formula (I) are both phosphodiesterase 4 (PDE4) enzyme inhibitors and muscarinic M3 receptor antagonists and are useful for the prevention and/or treatment of diseases of the respiratory tract characterized by airway obstruction.

Abstract: This document relates to methods and materials for detecting mutations that can be linked to dementia. For example, methods and materials for detecting one or more mutations within PGRN nucleic acid are provided. This document also provides methods and materials for detecting the level of progranulin expression. In addition, this document relates to methods and materials for treating mammals having a neurodegenerative disorder (e.g., dementia). For example, methods and materials for increasing PGRN polypeptide levels in mammals are provided, as are methods and materials for identifying agents that can be used to increase PGRN polypeptide levels in mammals.

Abstract: What is presented is an ultrasonic waveguide for the transmission of ultrasonic vibrations that establishes a plurality of node and anti-node positions that are each along the ultrasonic waveguide's central axis. The ultrasonic waveguide comprises a waveguide tube, which has both a proximal end and a distal end; a waveguide fitting, which has both a threaded end and a impact surface; and a spring, shock-pulsing mass, and stop. Both the spring and shock-pulsing mass are each positioned on the waveguide tube. Whereas, the stop is positioned on the waveguide tube and it is adapted to non-fixedly engage the spring and shock-pulsing mass. The impact surface of the waveguide fitting is located at an anti-node position, which is along the central axis of the ultra-sonic waveguide when its installed within ultrasonic transducer while in operation.