Patents by Inventor Chih-Min Liu

Chih-Min Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12217810
    Abstract: A circuit includes a plurality of anti-fuse cells coupled to a first selection circuit, a plurality of magnetic random-access memory (MRAM) cells coupled to a second selection circuit, an amplifier including a first input terminal coupled to each of the first and second selection circuits, an analog-to-digital converter (ADC) including input terminals coupled to output terminals of the amplifier, and a comparator including a first input port coupled to an output port of the ADC. The amplifier, ADC, and comparator are configured to output data bits from the comparator responsive to current levels received from the first selection circuit at the first input terminal of the amplifier and first voltage levels received from the second selection circuit at the first input terminal of the amplifier.
    Type: Grant
    Filed: March 11, 2024
    Date of Patent: February 4, 2025
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD.
    Inventor: Chih-Min Liu
  • Patent number: 12129242
    Abstract: The present invention provides novel substituted benzimidazole derivatives used as DAAO inhibitors and for treatment and/or prevention of neurological disorders.
    Type: Grant
    Filed: March 30, 2022
    Date of Patent: October 29, 2024
    Assignees: NATIONAL TAIWAN UNIVERSITY, NATIONAL YANG MING CHIAO TUNG UNIVERSITY, NATIONAL HEALTH RESEARCH INSTITUTES
    Inventors: Yufeng Jane Tseng, Yu-Li Liu, Chung-Ming Sun, Wen-Sung Lai, Chih-Min Liu, Hai-Gwo Hwu
  • Publication number: 20240242839
    Abstract: A prediction model training method includes the following steps. A first model is trained according to first electrocardiograms, wherein the first model includes a feature extraction layer, and the feature extraction layer is configured to extract features corresponding to an electrocardiogram. First feature information corresponding to second electrocardiograms is extracted according to the second electrocardiograms and the feature extraction layer of the first model. A second model is trained according to the first feature information, gender information corresponding to the second electrocardiograms, and age information corresponding to the second electrocardiograms.
    Type: Application
    Filed: April 27, 2023
    Publication date: July 18, 2024
    Inventors: Shin-Mu TSENG, Yu-Feng HU, Chih-Min LIU
  • Publication number: 20240212771
    Abstract: A circuit includes a plurality of anti-fuse cells coupled to a first selection circuit, a plurality of magnetic random-access memory (MRAM) cells coupled to a second selection circuit, an amplifier including a first input terminal coupled to each of the first and second selection circuits, an analog-to-digital converter (ADC) including input terminals coupled to output terminals of the amplifier, and a comparator including a first input port coupled to an output port of the ADC. The amplifier, ADC, and comparator are configured to output data bits from the comparator responsive to current levels received from the first selection circuit at the first input terminal of the amplifier and first voltage levels received from the second selection circuit at the first input terminal of the amplifier.
    Type: Application
    Filed: March 11, 2024
    Publication date: June 27, 2024
    Inventor: Chih-Min LIU
  • Patent number: 11929128
    Abstract: A circuit includes an operational amplifier including an inverting input terminal capacitively coupled to each of an OTP cell array and an NVM cell array and first and second output terminals, an ADC coupled to the first and second output terminals, thereby configured to receive a differential output voltage from the operational amplifier, and a comparator coupled to the ADC and configured to output a data bit responsive to a digital output signal received from the ADC. The circuit is configured to cause the operational amplifier to generate the differential output voltage based on each of a current received from an OTP cell of the OTP cell array and a voltage received from an NVM cell of the NVM cell array.
    Type: Grant
    Filed: March 27, 2023
    Date of Patent: March 12, 2024
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD.
    Inventor: Chih-Min Liu
  • Patent number: 11917316
    Abstract: A circuit is provided and includes first to second switching units, a sensing unit, and first to second capacitive units. The first switching unit and the second switching unit are alternately turned on in response to, respectively, a first control signal and a second control signal that have different voltage levels. First terminals of the first and second switching units are coupled to each other. A sensing unit generates a sensing voltage, in response to light, at the first terminals of the first and second switching units. The first capacitive unit generates a first voltage, in response to the sensing voltage, at a second terminal of the first switching unit. The second capacitive unit generates a second voltage, in response to the generating the sensing voltage, at a second terminal of the second switching unit.
    Type: Grant
    Filed: July 1, 2022
    Date of Patent: February 27, 2024
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventor: Chih-Min Liu
  • Patent number: 11869208
    Abstract: The present disclosure relates to methods, apparatuses, and computer programs for processing computed tomography images. Precise segmentation of the left atrium (LA) in computed tomography (CT) images constitutes a crucial preparatory step for catheter ablation in atrial fibrillation (AF). We aim to apply deep convolutional neural networks (DCNNs) to automate the LA detection/segmentation procedure and create a three-dimensional (3D) geometries. The deep learning provides an efficient and accurate way for automatic contouring and LA volume calculation based on the construction of the 3D LA geometry. Non-pulmonary vein (NPV) trigger has been reported as an important predictor of recurrence post atrial fibrillation (AF) ablation. Elimination of NPV triggers can reduce the post-ablation AF recurrence. The deep learning was applied in pre-ablation pulmonary vein computed tomography (PVCT) geometric slices to create a prediction model for NPV triggers in patients with paroxysmal atrial fibrillation (PAF).
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: January 9, 2024
    Assignees: TAIPEI VETERANS GENERAL HOSPITAL, National Yang Ming Chiao Tung University
    Inventors: Horng-Shing Lu, Chih-Min Liu, Shih-Lin Chang, Shih-Ann Chen, Yenn-Jiang Lin, Hung-Hsun Chen, Wei-Shiang Chen
  • Publication number: 20230238071
    Abstract: A circuit includes an operational amplifier including an inverting input terminal capacitively coupled to each of an OTP cell array and an NVM cell array and first and second output terminals, an ADC coupled to the first and second output terminals, thereby configured to receive a differential output voltage from the operational amplifier, and a comparator coupled to the ADC and configured to output a data bit responsive to a digital output signal received from the ADC. The circuit is configured to cause the operational amplifier to generate the differential output voltage based on each of a current received from an OTP cell of the OTP cell array and a voltage received from an NVM cell of the NVM cell array.
    Type: Application
    Filed: March 27, 2023
    Publication date: July 27, 2023
    Inventor: Chih-Min LIU
  • Patent number: 11615860
    Abstract: A circuit includes an array of OTP cells, an array of NVM cells, an amplifier coupled to each of the array of OTP cells and the array of NVM cells, and a control circuit configured to generate one or more control signals. Responsive to the one or more control signals, the amplifier is configured to generate an output voltage based on a current received from the array of OTP cells in a first configuration, and generate the output voltage based on a voltage received from the array of NVM cells in a second configuration.
    Type: Grant
    Filed: February 14, 2022
    Date of Patent: March 28, 2023
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD.
    Inventor: Chih-Min Liu
  • Publication number: 20220360732
    Abstract: A circuit is provided and includes first to second switching units, a sensing unit, and first to second capacitive units. The first switching unit and the second switching unit are alternately turned on in response to, respectively, a first control signal and a second control signal that have different voltage levels. First terminals of the first and second switching units are coupled to each other. A sensing unit generates a sensing voltage, in response to light, at the first terminals of the first and second switching units. The first capacitive unit generates a first voltage, in response to the sensing voltage, at a second terminal of the first switching unit. The second capacitive unit generates a second voltage, in response to the generating the sensing voltage, at a second terminal of the second switching unit.
    Type: Application
    Filed: July 1, 2022
    Publication date: November 10, 2022
    Applicant: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventor: Chih-Min LIU
  • Patent number: 11483468
    Abstract: Methods and systems for capturing a three dimensional image are described. An image capture process is performed while moving a lens to capture image data across a range of focal depths, and a three dimensional image reconstruction process generates a three dimensional image based on the image data. A two-dimensional image is also rendered including focused image data from across the range of focal depths. The two dimensional image and the three dimensional image are fused to generate a focused three dimensional model.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: October 25, 2022
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventor: Chih-Min Liu
  • Publication number: 20220306605
    Abstract: The present invention provides novel substituted benzimidazole derivatives used as DAAO inhibitors and for treatment and/or prevention of neurological disorders.
    Type: Application
    Filed: March 30, 2022
    Publication date: September 29, 2022
    Inventors: Yufeng Jane TSENG, Yu-Li LIU, Chung-Ming SUN, Wen-Sung LAI, Chih-Min LIU, Hai-Gwo HWU
  • Publication number: 20220267301
    Abstract: The present invention provides novel substituted benzimidazole derivatives used as DAAO inhibitors and for treatment and/or prevention of neurological disorders.
    Type: Application
    Filed: May 4, 2022
    Publication date: August 25, 2022
    Inventors: Yufeng Jane TSENG, Yu-Li LIU, Chung-Ming SUN, Wen-Sung LAI, Chih-Min LIU, Hai-Gwo HWU
  • Patent number: 11412167
    Abstract: A circuit is disclosed, including a sensing unit and first to fifth switching units. The sensing unit generates a sensing voltage to a sensing node. The first switching unit is coupled between the sensing node and a first node. The second switching unit is coupled between the sensing node and a second node and generates a first auxiliary voltage to the second node. The first capacitive unit is coupled to the second node. The third switching unit is coupled between the first and second nodes, and adjusts a first transfer voltage at the first node. The fourth switching unit is coupled between the sensing node and a third node, and generates a second transfer voltage to the third node. The fifth switching unit is coupled between the sensing node and a fourth node and generates a second auxiliary voltage to the fourth node.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: August 9, 2022
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventor: Chih-Min Liu
  • Patent number: 11370775
    Abstract: The present invention provides novel substituted benzimidazole derivatives of formula (I) used as DAAO inhibitors and for treatment and/or prevention of neurological disorders.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: June 28, 2022
    Assignees: NATIONAL TAIWAN UNIVERSITY, NATIONAL YANG MING CHIAO TUNG UNIVERSITY, NATIONAL HEALTH RESEARCH INSTITUTES
    Inventors: Yufeng Jane Tseng, Yu-Li Liu, Chung-Ming Sun, Wen-Sung Lai, Chih-Min Liu, Hai-Gwo Hwu
  • Publication number: 20220165344
    Abstract: A circuit includes an array of OTP cells, an array of NVM cells, an amplifier coupled to each of the array of OTP cells and the array of NVM cells, and a control circuit configured to generate one or more control signals. Responsive to the one or more control signals, the amplifier is configured to generate an output voltage based on a current received from the array of OTP cells in a first configuration, and generate the output voltage based on a voltage received from the array of NVM cells in a second configuration.
    Type: Application
    Filed: February 14, 2022
    Publication date: May 26, 2022
    Inventor: Chih-Min LIU
  • Patent number: 11270780
    Abstract: A circuit includes an OTP cell, an NVM cell, and a bit line coupled to the OTP cell, the NVM cell, and a first input terminal of an amplifier. The amplifier is configured to generate an output voltage based on a signal on the bit line, an ADC is configured to generate a digital output signal based on the output voltage, and a comparator includes a first input port coupled to an output port of the ADC and is configured to output a data bit responsive to a comparison of the digital output signal to a threshold level received at a second input port.
    Type: Grant
    Filed: September 22, 2020
    Date of Patent: March 8, 2022
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD.
    Inventor: Chih-Min Liu
  • Publication number: 20210304832
    Abstract: A circuit includes an OTP cell, an NVM cell, and a bit line coupled to the OTP cell, the NVM cell, and a first input terminal of an amplifier. The amplifier is configured to generate an output voltage based on a signal on the bit line, an ADC is configured to generate a digital output signal based on the output voltage, and a comparator includes a first input port coupled to an output port of the ADC and is configured to output a data bit responsive to a comparison of the digital output signal to a threshold level received at a second input port.
    Type: Application
    Filed: September 22, 2020
    Publication date: September 30, 2021
    Inventor: Chih-Min LIU
  • Publication number: 20210287365
    Abstract: The present disclosure relates to methods, apparatuses, and computer programs for processing computed tomography images. Precise segmentation of the left atrium (LA) in computed tomography (CT) images constitutes a crucial preparatory step for catheter ablation in atrial fibrillation (AF). We aim to apply deep convolutional neural networks (DCNNs) to automate the LA detection/segmentation procedure and create a three-dimensional (3D) geometries. The deep learning provides an efficient and accurate way for automatic contouring and LA volume calculation based on the construction of the 3D LA geometry. Non-pulmonary vein (NPV) trigger has been reported as an important predictor of recurrence post atrial fibrillation (AF) ablation. Elimination of NPV triggers can reduce the post-ablation AF recurrence. The deep learning was applied in pre-ablation pulmonary vein computed tomography (PVCT) geometric slices to create a prediction model for NPV triggers in patients with paroxysmal atrial fibrillation (PAF).
    Type: Application
    Filed: March 15, 2021
    Publication date: September 16, 2021
    Applicants: TAIPEI VETERANS GENERAL HOSPITAL, National Yang Ming Chiao Tung University
    Inventors: Horng-Shing Lu, Chih-Min Liu, Shih-Lin Chang, Shih-Ann Chen, Yenn-Jiang Lin, Hung-Hsun Chen, Wei-Shiang Chen
  • Patent number: RE49340
    Abstract: The invention utilizes virtual screening strategy to seek for current market drugs as anti-schizophrenia therapy drug repurposing. Drug repurposing strategy finds new uses other than the original medical indications of existing drugs. Finding new indications for such drugs will benefit patients who are in needs for a potential new therapy sooner since known drugs are usually with acceptable safety and pharmacokinetic profiles. In this study, repurposing marketed drugs for DAAO inhibitor as new schizophrenia therapy was performed with virtual screening on marketed drugs and its metabolites. The identified and available drugs and compounds were further confirmed with in vitro DAAO enzymatic inhibitory assay.
    Type: Grant
    Filed: May 2, 2019
    Date of Patent: December 20, 2022
    Assignees: National Taiwan University, National Yang Ming Chiao Tung University, National Health Research Institutes
    Inventors: Yufeng Jane Tseng, Yu-Li Liu, Chung-Ming Sun, Hai-Gwo Hwu, Chih-Min Liu, Wen-Sung Lai