Abstract: The present invention relates to an improved asymmetric synthesis of alpha-(diarylmethyl) alkyl amines (hereafter referred to as the compound (1)) or its pharmaceutically acceptable salt and derivatives. The process comprises an unusual substrate specific regioselective lithiation of alpha-diarylmethanes. followed by its highly diastereoselective addition to N-tert-butanesulfinylimines resulting in the selective formation of chiral alpha-(diarylmethyl) alkyl amines 4 and chiral amine 5; which on subsequently removing the sulfinyl group provides corresponding alpha-(diarylmethyl) alkyl amines (1) or relative chiral amines (1?).

Abstract: Methods, systems, and devices for wireless communication are described. The payload size for uplink transmissions of unscheduled control information may vary and, in some cases, may be dynamically determined. A user equipment (UE) may determine a payload size or may select a payload size from a set of predetermined sizes. A base station may independently determine the same payload size or it may blindly detect the payload size upon receiving the uplink (UL) transmission. Or the base station may indicate the payload size to the UE. Additionally, UL grants issued to the UE may take one of several forms (e.g., different downlink control indicator formats), and characteristics of the grant may indicate information about resources assigned by the grant, including a location of the resources among various transmission opportunities or whether the grant is for multiple subframes.

Abstract: The present invention relates to an improved process for diastereoselective synthesis of vicinal diamines (1). The process involves highly regio- and diastereoselective addition of 2-azaallyl anions (4) to N-tert-butanesulfinylimines (5) to produce vicinal diamines (1).

Abstract: Exercise class systems and methods may include a plurality of pieces of exercise equipment and/or a plurality of sensing systems adapted to be worn on people in the class, each piece of equipment or sensing system outputting plural exercise signals relating to exercise performance on the piece of equipment or of the person with the sensing system. A computer system may also be provided. The computer system may include at least one electronic storage device which stores the plural signals from the pieces of equipment or sensing system and at least one processor which generates an output signal containing an animation corresponding to at least two of the exercise signals from each of the pieces of equipment or sensing systems. At least one display device, visible from each of the pieces of equipment or people in the class, may receive the output signal and display the animation.

Abstract: Existing currency validation (CVAL) devices, systems, and methods are too slow, costly, intrusive, and/or bulky to be routinely used in common transaction locations (e.g., at checkout, at an automatic teller machine, etc.). Presented herein are devices, systems, and methods to facilitate optical validation of documents, merchandise, or currency at common transaction locations and to do so in an obtrusive and convenient way. More specifically, the present invention embraces a validation device that may be used alone or integrated within a larger system (e.g., point of sale system, kiosk, etc.). The present invention also embraces methods for currency validation using the validation device, as well as methods for improving the quality and consistency of data captured by the validation device for validation.

Abstract: The present invention relates to an improved asymmetric synthesis of azaspiro or diazaspiro compound (hereafter referred to as the compound 5, (5A) or (5N)) or their pharmaceutically acceptable salts and derivatives; through the formation of intermediate compounds 4, (4A) or (4N) respectively. The process comprises an unusual substrate specific highly diastereoselective as well as enantio-enriched 1-substituted 2-azaspiro[3.3]heptane or 1-substituted 2-diazaspiro[3.3]heptane compounds with high diastereoselectivity by addition of a cyclobutane carboxylate anion to a Davis-Ellman's imine, followed by reduction and cyclisation resulting in the selective formation of azaspiro or diazaspiro intermediate compound 4, (4A) or (4N); which on subsequently removing the sulfinyl group provides corresponding azaspiro or diazaspiro compound 5, (5A) or (5N) respectively.

Abstract: Exercise class systems and methods may include a plurality of pieces of exercise equipment and/or a plurality of sensing systems adapted to be worn on people in the class, each piece of equipment or sensing system outputting plural exercise signals relating to exercise performance on the piece of equipment or of the person with the sensing system. A computer system may also be provided. The computer system may include at least one electronic storage device which stores the plural signals from the pieces of equipment or sensing system and at least one processor which generates an output signal containing an animation corresponding to at least two of the exercise signals from each of the pieces of equipment or sensing systems. At least one display device, visible from each of the pieces of equipment or people in the class, may receive the output signal and display the animation.

Abstract: In embodiments of the present invention, features of an improved user authentication system features include receiving, by a processor of a computer system receiving a request for authorizing a first user, transmitting a prompt to a second user, receiving a first code from the second user, and transmitting the first code to a network location, and enabling access for the second user to the network location. Methods and systems include transmitting the first code to a network location accessible by authorized users.

Abstract: Methods, systems, and devices for wireless communication are described. Various autonomous uplink control channel configurations may be used for unscheduled uplink transmissions. For example, a user equipment (UE) may initiate an unscheduled uplink transmission and may identify an autonomous uplink control channel configuration for the uplink transmission. The UE may transmit control information and data during an initial transmission time interval of a transmission opportunity according to the control channel configuration, where the control channel configuration control may include a number of different waveforms and payload configurations. For example, an autonomous uplink control channel configuration may include control information frequency division multiplexed or time division multiplexed with data and transmitted in one or more frequency interlaces.

Abstract: Methods, systems, and devices for wireless communication are described. A base station may identify a semi-static resource allocation for a device (e.g., a user equipment (UE)). The resource allocation may be associated with autonomous transmissions from the device in an unlicensed radio frequency spectrum band. The base station may generate and provide a message for transmission to the device. The message may convey an indication of the resource allocation. The device may receive the message and use the resource allocation to identify a transmission schedule for the autonomous transmissions.

Abstract: The present invention relates to an improved asymmetric synthesis of alpha-branched amines (hereafter referred to as the compound) and relative chiral amines (1?) or its pharmaceutically acceptable salt and derivatives. The process comprises an unusual substrate specific regioselective ortho lithiation of substituted arene compounds, followed by its highly diastereoselective addition to N-tert-butanesulfinylimines resulting in the selective formation of alpha-branched sulfinyl amine and chiral amine; which on subsequently removing the sulfinyl group provides corresponding alpha-branched amines or relative chiral amines (1?).

Abstract: The present invention relates to an improved asymmetric synthesis of alpha-(diarylmethyl) alkyl amines (hereafter referred to as the compound (1)) or its pharmaceutically acceptable salt and derivatives. The process comprises an unusual substrate specific regioselective lithiation of alpha-diarylmethanes, followed by its highly diastereoselective addition to N-tert-butanesulfinylimines resulting in the selective formation of chiral alpha-(diarylmethyl) alkyl amines 4 and chiral amine 5; which on subsequently removing the sulfinyl group provides corresponding alpha-(diarylmethyl) alkyl amines (1) or relative chiral amines (1?).

Abstract: A method and apparatus for wireless communication in the unlicensed spectrum between an eNB and UEs having different bandwidths, e.g., between a narrowband UE and a wideband eNB. A base station apparatus may perform a dual CCA procedure for a frame, wherein the dual CCA procedure comprises a first type of CCA procedure followed by a second type of CCA procedure when the first type of CCA procedure is unsuccessful. The apparatus may transmit during the frame when at least one CCA procedure of the dual CCA procedure is successful and may refrain from transmitting during the frame when both CCA procedures of the dual CCA procedure are unsuccessful. In performing the dual CCA procedure, the apparatus may perform CCA for a first period of time then perform eCCA for a second period of time following the CCA, when the CCA is unsuccessful.

Abstract: Certain aspects of the present disclosure relate to a methods and apparatus for wireless communication. In one aspect, a method of wireless communication comprises assigning, by an access point, an interval of time for transmission on an unlicensed communication spectrum to a LTE-U device, and broadcasting an anchor signal during the interval of time on the unlicensed communication spectrum, the anchor signal comprising a paging indication for the LTE-U device. In another aspect, a method of wireless communication comprises determining, by a LTE-U device, an interval of time for reception of a paging indication on an unlicensed communication spectrum and receiving an anchor signal during the interval of time on the unlicensed communication spectrum, the anchor signal comprising the paging indication.

Abstract: Methods, systems, and devices for wireless communication are described. The payload size for uplink transmissions of unscheduled control information may vary and, in some cases, may be dynamically determined. A user equipment (UE) may determine a payload size or may select a payload size from a set of predetermined sizes. A base station may independently determine the same payload size or it may blindly detect the payload size upon receiving the uplink (UL) transmission. Or the base station may indicate the payload size to the UE. Additionally, UL grants issued to the UE may take one of several forms (e.g., different downlink control indicator formats), and characteristics of the grant may indicate information about resources assigned by the grant, including a location of the resources among various transmission opportunities or whether the grant is for multiple subframes.

Abstract: In an aspect of the disclosure, a method, a computer-readable medium, and an apparatus for wireless communication are provided. The apparatus may be a base station. The apparatus may transmit an uplink grant to a UE during a first transmit opportunity. The apparatus may signal, during a second transmit opportunity, a grant trigger to the UE to trigger operations associated with the uplink grant that are uncompleted after the first transmit opportunity. The grant trigger may be associated with a set of UEs that includes the UE. The set of UEs may be a subset of the UEs having pending transmissions. The apparatus may instruct the UE regarding whether to keep or discard resources granted by the uplink grant when the UE switches to a different beam during or prior to the second transmit opportunity.

Abstract: Provided herein are engineered TSC2 polypeptides, and nucleic acid sequences encoding them, in which the ability of a serine residue to be phosphorylated is altered. In some aspects, the TSC2 serine residue cannot be phosphorylated (e.g., by substituting the serine residue with an alanine residue). In some aspects, the TSC2 serine acts as if it is constitutively phosphorylated (e.g., by substituting the serine residue with a glutamic acid residue). Also provided herein are engineered immune cells comprising altered TSC2 polypeptides or nucleic acid sequences encoding them, and methods of making and using such engineered immune cells.

Abstract: Techniques for operator identification on a shared communication medium are disclosed. An access point may determine an operator identifier for an operator associated with an access point and configure a set of resource elements to carry an operator identifier reference signal embedded with the operator identifier. The access point may then transmit the operator identifier reference signal using the configured set of resource elements. An access terminal may receive signaling from an access point on a set of resource elements and monitor the signaling for an operator identifier reference signal. The access terminal may then determine an operator identifier for an operator associated with the access point based on the operator identifier reference signal.

Abstract: Methods are provided for authenticating a value article that includes a luminescent material. An exciting light source, an optical filter, a photodetector, a signal manipulation circuit, and an amplifier are provided. The luminescent material is exposed to light produced by the exciting light source. Radiation including light from the exciting light source and emitted radiation from the luminescent material is filtered using the optical filter to produce filtered radiation. The filtered radiation is detected using the photodetector to produce a detected radiation signal. The detected radiation signal is electronically manipulated using the signal manipulation circuit to reduce an effect of light from the exciting light source on an authentication determination based upon the detected radiation signal. The detected radiation signal is amplified with the amplifier after electronic manipulation to produce an amplified electronic signal.

Abstract: A method and apparatus for wireless communication in the unlicensed spectrum between an eNB and UEs having different bandwidths, e.g., between a narrowband UE and a wideband eNB. A UE apparatus transmits uplink transmissions in a plurality of transmission units and hops frequency bands in a first pattern across frames based on a base station hopping pattern. The apparatus may transmit uplink transmissions based on dual hopping patterns, and may hop in a second pattern across transmission units within the base station's channel occupancy within a frame. A base station apparatus may hop frequency bands in a first pattern across frames based on a base station hopping pattern, and may receive uplink transmissions in a narrowband from a UE in a plurality of transmission units within the frequency bands based on the base station hopping pattern.