Patents by Inventor Christian Fischer

Christian Fischer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10442819
    Abstract: The present invention is directed to tricyclic compounds of formula (I) which are inhibitors of one or more mutant IDH enzymes: (I). The present invention is also directed to uses of the tricyclic compounds described herein in the potential treatment or prevention of cancers in which one or more mutant IDH enzymes are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such cancers.
    Type: Grant
    Filed: December 1, 2015
    Date of Patent: October 15, 2019
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Christian Fischer, Stephane L. Bogen, Matthew L. Childers, Francesc Xavier Fradera Llinas, J. Michael Ellis, Sara Esposite, Qingmei Hong, Chunhui Huang, Alexander J. Kim, John W. Lampe, Michelle R. Machacek, Daniel R. McMasters, Ryan D. Otte, Dann L. Parker, Jr., Michael Reutershan, Nunzio Sciammetta, Pengcheng P. Shao, David L. Sloman, Feroze Ujjainwalla, Catherine White, Zhicai Wu, Yang Yu, Kake Zhao, Craig Gibeau, Tesfaye Biftu, Purakkattle Biju, Lei Chen, Joshua Close, Peter H. Fuller, Xianhai Huang, Min K. Park, Valdimir Simov, David J. Witter, Hongjun Zhang
  • Publication number: 20190308273
    Abstract: A flow control device for an additive manufacturing system is provided. The flow control device includes a gas supply configured to discharge a gas, a first flow modifier configured to modify at least one flow characteristic of a first portion of the gas, and a second flow modifier configured to cooperate with the first flow modifier to modify the at least on flow characteristic of the first portion of the gas. The second flow modifier is further configured to modify at least one flow characteristic of a second portion of the gas, and the first flow modifier and the second flow modifier are configured to cooperate to direct at least a portion of the first portion and the second portion of the gas towards a melt pool in a plurality of particles.
    Type: Application
    Filed: April 9, 2018
    Publication date: October 10, 2019
    Inventors: Christian Wakelam, Rene du Cauze de Nazelle, Daniel Fischer, Hannes Haderlein, Viktor Engel, Florian Hoefler, Rachel Wyn Levine
  • Patent number: 10434184
    Abstract: The invention provides anti-TPBG antibodies and methods of using the same.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: October 8, 2019
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Stefan Dengl, Sebastian Fenn, Jens Fischer, Thomas Friess, Sabine Imhof-Jung, Ben-Fillippo Krippendorff, Christian Schantz, Tilman Schlothauer, Claudio Sustmann, Barbara Weiser, Adrian Zwick
  • Patent number: 10434180
    Abstract: The present application relates to methods for the enzymatic functionalization of immunoglobulins, in particular with drugs. Also disclosed herein are linking reagents, functionalized antibodies, pharmaceutical compositions, and method of treating disease and/or conditions.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: October 8, 2019
    Assignees: INNATE PHARMA, PAUL SCHERRER INSTITUT
    Inventors: Delphine Bregeon, Patrick Dennler, Christian Belmant, Laurent Gauthier, François Romagne, Eliane Fischer, Roger Schibli
  • Patent number: 10427589
    Abstract: The present invention relates to a work lighting (100) for a machine (200) for generating an adaptive working illumination, comprising a plurality of lighting means (10) arranged in the form of a light-emitting matrix (20) to generate the working illumination, and at least one central adjusting unit (60, 70, 80) for separately adjusting the working illumination of the individual lighting means (10) in the light-emitting matrix. The invention further relates to a machine (200) having a work lighting (100) according to the invention.
    Type: Grant
    Filed: November 5, 2018
    Date of Patent: October 1, 2019
    Assignee: HELLA GmbH & Co. KGaA
    Inventors: Michael Aichinger-Rosenberger, Dominik Fischer, Andreas Hingel, Christoph Jandrisits, Gerhard Berger, Bernhard Zettl, Christian Derkits, Karlheinz Kellner, Thomas Posnicek
  • Patent number: 10414087
    Abstract: A structure stamp has a flexible stamp which has a microstructured or nanostructured stamp surface for embossing of an embossing structure which corresponds to the stamp surface on an embossing surface, and a frame for clamping the stamp. Moreover, the invention relates to a device for embossing an embossing pattern on an embossing surface with the following features: a stamp receiver for accommodating and moving a structure stamp, an embossing material receiver for accommodating and placing an embossing material opposite the structure stamp, and an embossing element drive for moving an embossing element along the structure stamp.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: September 17, 2019
    Assignee: EV GROUP E. THALLNER GMBH
    Inventors: Peter Fischer, Gerald Kreindl, Jakob Harming, Christine Thanner, Christian Schon
  • Patent number: 10418637
    Abstract: The invention relates to a grid arrangement for a plate-shaped battery electrode of an electrochemical accumulator comprising a frame and a grid arranged thereon, wherein the frame comprises at least one upper frame element having a connecting lug of the battery electrode disposed on its side facing away from the grid, wherein the grid comprises grid bars respectively surrounding cutouts of the grid, wherein the majority of the grid bars surrounding the cutouts are respectively disposed in a hexagonal arrangement such that the cutout situated in between forms a hexagon, characterized by one, some or all of the following a), b), c), d), e) features): a) the grid arrangement is coated with a pasty active mass on which liquid-absorbing material designed to absorb liquid electrolyte of the accumulator is disposed, b) the size of the hexagonal cutouts increases toward the upper frame element, c) the grid bars of all the hexagonal cutouts have the same width or the same cross-sectional area, d) none of the grid ba
    Type: Grant
    Filed: October 21, 2014
    Date of Patent: September 17, 2019
    Assignee: Johnson Controls Autobatterie GmbH & Co. KGaA
    Inventors: Ingo Koch, Bernd Ide, Frank-Thomas Johns, Armin Staffeldt, Andreas Dudenbostel, Dirk Goebbels, Christian Fischer, Juergen Bauer
  • Publication number: 20190275167
    Abstract: The disclosure features pharmaceutical compositions formed from prodrug dimers for the extended delivery of a drug and for the treatment of a disease or condition.
    Type: Application
    Filed: April 26, 2019
    Publication date: September 12, 2019
    Inventors: Ian Charles PARRAG, Matthew Alexander John STATHAM, Kyle BATTISTON, Dimitra LOUKA, Hans Christian FISCHER, J. Paul SANTERRE, Wendy Alison NAIMARK
  • Patent number: 10403298
    Abstract: An information encoder for encoding an information signal includes: a converter for converting the linear prediction coefficients of the predictive polynomial A(z) to frequency values f1 . . . fn of a spectral frequency representation of the predictive polynomial A(z), wherein the converter is configured to determine the frequency values f1 . . . fn by analyzing a pair of polynomials P(z) and Q(z) being defined as P(z)=A(z)+z?m?lA(z?1) and Q(z)=A(z)?z?m?lA(z?1), wherein m is an order of the predictive polynomial A(z) and l is greater or equal to zero, wherein the converter is configured to obtain the frequency values by establishing a strictly real spectrum derived from P(z) and a strictly imaginary spectrum from Q(z) and by identifying zeros of the strictly real spectrum derived from P(z) and the strictly imaginary spectrum derived from Q(z).
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: September 3, 2019
    Assignee: Fraunhofer-Gesellschaft zur Foerderung der angewandten Forschung e.V.
    Inventors: Tom Baeckstroem, Christian Fischer Pedersen, Johannes Fischer, Matthias Huettenberger, Alfonso Pino
  • Publication number: 20190247311
    Abstract: The disclosure features dexamethasone prodrug dimers of dexamethasone and pharmaceutical compositions thereof useful for, e.g., the extended release of a drug and for the treatment of a disease or condition.
    Type: Application
    Filed: April 26, 2019
    Publication date: August 15, 2019
    Inventors: Ian Charles PARRAG, Matthew Alexander John STATHAM, Kyle BATTISTON, Dimitra LOUKA, Hans Christian FISCHER, J. Paul SANTERRE, Wendy Alison NAIMARK
  • Patent number: 10370753
    Abstract: The invention relates to a method for applying a protective coating (10) to a flat steel product (100), wherein the protective coating (10) is produced by guiding the flat steel product (100) having a strip entry temperature of 400-490 degrees Celsius through a molten zinc alloy bath. The molten zinc alloy bath (11) has a bath temperature of 400-480 degrees Celsius and contains an aluminum fraction and a magnesium fraction. In particular, the molten zinc alloy bath (11) has the following composition: the aluminum fraction is in the range between 1.8 and 3.0 weight percent; the magnesium fraction is in the range between 1.3 and 2.7 weight percent; the aluminum fraction in weight percent is greater than the magnesium fraction in weight percent; the ratio of the magnesium fraction in weight percent to the sum of the aluminum fraction in weight percent and the magnesium fraction in weight percent is in the range between 0.31 and 0.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: August 6, 2019
    Assignee: VOESTALPINE STAHL GMBH
    Inventors: Christian K. Riener, Gerhard Angeli, Klaus Hofer, Wilhelm Fischer
  • Publication number: 20190217815
    Abstract: A seatbelt tensioner for a seat belt retractor, having a pipe (1) with a tensioner drive wheel. A pyrotechnical gas generator (10), a piston (3), and at least one mass body (4) in the pipe (1), wherein the at least one mass body (4) is drivable by the pressure generable by the gas generator (10) and acting on the piston (3) between the gas generator (10) and a mass body (4), and which can be made to mesh in a force-transmitting manner with the tensioner drive wheel, thus driving a belt shaft of the seat belt retractor in a belt tensioning direction. The pipe (1) has a receiving section (5) with a first inner diameter (2), in which the piston (3) in its initial state is arranged with an initial-state outer diameter (8) prior to the ignition of the gas generator (10). The pipe (1) has a guide section (6) which adjoins the receiving section (5) and which has a second inner diameter (7).
    Type: Application
    Filed: January 3, 2019
    Publication date: July 18, 2019
    Applicant: AUTOLIV DEVELOPMENT AB
    Inventors: CHRISTIAN FISCHER, MARKUS FURCHERT
  • Patent number: 10350742
    Abstract: Percussion unit, especially for a rotary hammer and/or percussion hammer, comprising a control unit which is designed for controlling a pneumatic percussion mechanism. According to the disclosure, the control unit comprises at least one load estimation device.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: July 16, 2019
    Assignee: Robert Bosch GmbH
    Inventors: Rainer Nitsche, Antoine Vandamme, Thomas Winkler, Helge Sprenger, Haris Hamedovic, Wolfgang Fischer, Christian Bertsch, Mario Eduardo Vega Zavala, Ulli Hoffmann, Thilo Henke, Achim Duesselberg
  • Publication number: 20190211422
    Abstract: The present invention relates to novel composite materials enriched with silicon dispersed in matrices comprising Ni, Ti and Si and/or Sn, optionally passivated, the method for producing said materials and to the use of same as electrodes. The invention further relates to the aforementioned matrices and the synthesis thereof.
    Type: Application
    Filed: May 18, 2017
    Publication date: July 11, 2019
    Applicants: Centre National D'Etudes Spatiales, SAFT, Centre National de la recherche scientifique, Université de Montpellier
    Inventors: Christian JORDY, Florent FISCHER, Fermin CUEVAS, Alix LADAM, Laurent ALDON, Pierre-Emmanuel LIPPENS, Nicolas BIBENT, Josette OLIVER-FOURCADE, Jean-Claude JUMAS
  • Patent number: 10346570
    Abstract: A method for determining system reliability of a logic circuit, wherein a functional component model for design/simulation of a circuit model of the logic circuit is created, where functional components model are expanded by adding an associated power model, a temperature model, and a reliability, where the logic circuit is constructed with expanded model components and, based on simulation of the logic circuit aided by the constructed circuit model, a functional, a power-dependent, and a temperature-dependent behavior and a temperature-dependent failure rate are derived for each component in a component specific manner for a specified application case, and where in addition to the functional behavior, a power and temperature behavior and a total failure rate can be determined simply and dynamically, based on the derived data and dependent on temperature and simulation time for the logic circuit for the specified application case.
    Type: Grant
    Filed: July 22, 2015
    Date of Patent: July 9, 2019
    Assignee: Siemens AG Österreich
    Inventors: Christian Cech, Bernhard Fischer, Thomas Hinterstoisser, Martin Matschnig
  • Patent number: 10330613
    Abstract: A spectroscopic method for calculating a limit of quantification and a relative error includes: 1. selecting an error function F(C); 2. providing a blank spectrum; 3. recording a reference spectrum with a signal content of the substance being investigated; 4. determining start concentrations; 5.a. multiplying the reference spectrum with the signal content of the substance by a factor; 5.b. adding the resulting spectrum to the blank spectrum and determining the corresponding concentration of the substance and calculating the corresponding relative error; 6. iteratively adapting parameters of the selected error function F(C): recording a measurement spectrum of the test sample and determining the concentration of the substance being investigated using 5.b. and comparing with the calculated limit of quantification and calculating the relative error by applying the error function from step 6.
    Type: Grant
    Filed: October 19, 2016
    Date of Patent: June 25, 2019
    Assignee: BRUKER BIOSPIN GMBH
    Inventors: Christian Fischer, Carsten Kuhl, Kimberly Colson
  • Publication number: 20190176500
    Abstract: An apparatus and a method for embossing micro- and/or nanostructures in an embossing material.
    Type: Application
    Filed: September 5, 2016
    Publication date: June 13, 2019
    Applicant: EV Group E. Thallner GmbH
    Inventors: Friedrich Paul Lindner, Harald Zaglmayr, Christian Schon, Thomas Glinsner, Evelyn Reisinger, Peter Fischer, Othmar Luksch
  • Publication number: 20190169941
    Abstract: The invention relates to a working machine and a method for working the ground with the working machine, having a mast, along which, by means of a positioning means, a rotary head is moved vertically, by which a telescopic Kelly rod having at least two Kelly bars is displaced and guided. According to the invention the Kelly bars are locked or unlocked automatically by means of a control, wherein by means of a first detection means a rotation angle of at least one Kelly bar is detected and/or by means of a second detection means a force, torque or pressure change is detected in a hydraulic system. By the control a locking and/or unlocking of the Kelly bars is determined depending on the detected rotation angle and/or the detected change.
    Type: Application
    Filed: July 12, 2017
    Publication date: June 6, 2019
    Applicant: BAUER Maschinen GmbH
    Inventors: Sebastian BAUER, Christian FISCHER, Andreas SCHOBER
  • Publication number: 20190165335
    Abstract: An electrochemical cell includes an annular electrode composite body; and an annular liquid-tight housing formed as a hollow cylinder and including an annular interior space, wherein the housing is arranged around a central aperture or recess, the housing has a height of 5 mm to 40 mm and an external diameter of 6 mm to 20 mm, and the annular electrode composite body is arranged in the annular interior space.
    Type: Application
    Filed: July 18, 2017
    Publication date: May 30, 2019
    Inventors: Bernd Kreidler, Goran Kilibarda, Rainer Hald, Winfried Gaugler, Claus-Christian Fischer, Jürgen Ernsperger, Rolf Brenner
  • Publication number: 20190143882
    Abstract: The present invention relates to a work lighting (100) for a machine (200) for generating an adaptive working illumination, comprising a plurality of lighting means (10) arranged in the form of a light-emitting matrix (20) to generate the working illumination, and at least one central adjusting unit (60, 70, 80) for separately adjusting the working illumination of the individual lighting means (10) in the light-emitting matrix. The invention further relates to a machine (200) having a work lighting (100) according to the invention.
    Type: Application
    Filed: November 5, 2018
    Publication date: May 16, 2019
    Inventors: Michael Aichinger-Rosenberger, Dominik Fischer, Andreas Hingel, Christoph Jandrisits, Gerhard Berger, Bernhard Zettl, Christian Derkits, Karlheinz Kellner, Thomas Posnicek