Abstract: The invention relates to a belt tightener (1) with a mass body drive for a seat belt of a motor vehicle with a force-limiting device with—a belt shaft (3) mounted rotatably in at least one opening (15) of a housing (14) that can be fastened fixedly to the vehicle, it being possible to wind up the seat belt on said shaft, —a tightener drive wheel (24) connected non-rotatably to the belt shaft (3) and having recesses (14) distributed at regular intervals over the circumference, —a chain forming the mass body drive made of loose mass bodies (19), which are guided in a tightener tube (10) and can be driven by pressure application of the tightener tube (10), wherein—the belt shaft (3) can be driven in the winding direction of the seat belt by engagement of the driven mass bodies (19) in the recesses (14) of the tightener drive wheel (24), wherein—the mounting of the belt shaft (3) in the opening (15) of the housing (14) is designed to be flexible in the radial direction.

Abstract: Described herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof. The compounds of Formula (I) act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.

Abstract: The present invention relates to compounds of formula (A), wherein Z is NR10 or O. These compounds represent novel acridinium and xanthylium salts having an unprecedented substituted heterocyclic core. They are useful as fluorescent dyes or precursors thereof in different applications including various imaging and sensing techniques, and, in particular, as photosensitizers and hereby preferably as photocatalysts. The present invention further relates to processes for preparing the inventive compounds via 1,5-organodimetallic reagents from double directed ortho-metalation reactions or combined halogen-metal exchange/directed ortho-metalation reactions.

Abstract: A pyrotechnic tightening device of a safety belt unit having a force-limiting unit, comprising—a gas generator, and—a piston, which is guided in a pipe and which closes a pressure chamber inside the pipe, wherein—a pressure can be applied to the pressure chamber by the gas generator, and—the piston can be driven by the pressure present in the pressure chamber to perform a tightening movement which can be transmitted by means of a force-transmitting unit to the safety belt, wherein—the piston is formed in two parts consisting of a main body and a contact part arranged on the side of the main body facing the force-transmitting unit, wherein—the contact part has a greater strength than the main body, wherein—the main body surrounds the contact part form-fittingly at the end face facing the force-transmitting device.

Abstract: An information encoder for encoding an information signal includes: a converter for converting the linear prediction coefficients of the predictive polynomial A(z) to frequency values f1 . . . fn of a spectral frequency representation of the predictive polynomial A(z), wherein the converter is configured to determine the frequency values f1 . . . fn by analyzing a pair of polynomials P(z) and Q(z) being defined as P ? ( z ) = A ? ( z ) + z - m - l ? A ? ( z - 1 ) ? ? and Q ? ( z ) = A ? ( z ) - z - m - l ? A ? ( z - 1 ) , wherein m is an order of the predictive polynomial A(z) and I is greater or equal to zero, wherein the converter is configured to obtain the frequency values by establishing a strictly real spectrum derived from P(z) and a strictly imaginary spectrum from Q(z) and by identifying zeros of the strictly real spectrum derived from P(z) and the strictly imaginary spectrum derived from Q(z).

Abstract: A system, method and computer program product for detecting indicators for structural changes of NMR active test molecules in a test sample, or indicators for structural changes of the environment of said test molecules in relation to a reference molecule. Initial local similarity values are obtained, using a similarity function and representing a local similarity between a reference spectrum and a test spectrum within corresponding similarity regions (SRR, SRT). The initial local similarity values represent a similarity map (SM1) in which contours of a first shape type are indicators (I1) for structural changes of the test molecule, and in which contours of a second shape type are indicators (I2) for structural changes of the environment of said test molecule in relation to the reference molecule.

Abstract: An information encoder for encoding an information signal includes: a converter for converting the linear prediction coefficients of the predictive polynomial A(z) to frequency values f1 . . . fn of a spectral frequency representation of the predictive polynomial A(z), wherein the converter is configured to determine the frequency values f1 . . . fn by analyzing a pair of polynomials P(z) and Q(z) being defined as P(z)=A(z)+z?m?lA(z?1) and Q(z)=A(z)?z?m?lA(z?1), wherein m is an order of the predictive polynomial A(z) and l is greater or equal to zero, wherein the converter is configured to obtain the frequency values by establishing a strictly real spectrum derived from P(z) and a strictly imaginary spectrum from Q(z) and by identifying zeros of the strictly real spectrum derived from P(z) and the strictly imaginary spectrum derived from Q(z).

Abstract: The disclosure features dexamethasone prodrug dimers of dexamethasone and pharmaceutical compositions thereof useful for, e.g., the extended release of a drug and for the treatment of a disease or condition.

Abstract: An improved photosensitizer for a photocathode comprises an oligomeric or polymeric chromphore absorbing, as an ensemble, light at (a) wavelengths at or greater than 420 nm that includes at least 3 identical or different suitable monomeric chromophore units carrying at least two substituents each comprising at least one alkylene, alkenylene and/or alkynylene chain having a chain length of at least 3 carbon atoms, those substituents being terminated by thiol groups, wherein the oligomeric or polymeric chromphore has a disulfide bond between each of the chromophores. A photocathode comprising the photosensitzer is useful for the reduction of water-soluble chemicals in oxidized forms, including protons, with the aid of visible light in a system comprising the photocathode and a photoanode or any other anode or source of electrons. A method for reducing chemicals soluble in aqueous media in oxidized forms, including protons, in aqueous solutions by means of the photocathode is also disclosed.

Abstract: Described herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof. The compounds of Formula (I) act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.

Abstract: The disclosure features pharmaceutical compositions formed from prodrug dimers for the extended delivery of a drug and for the treatment of a disease or condition.

Abstract: A secondary lithium battery includes (a) a housing enclosing an interior space, and (b) a composite body arranged in the interior space and including at least one positive electrode, at least one negative electrode and at least one separator, wherein (c) the housing includes a metal housing part having an inner side pointing into the interior space and an outer side pointing away from the interior space, and (d) the metal housing part includes: a first layer consisting of aluminium or an aluminium alloy that forms the inner side of the metal housing part, and in direct contact with the first layer, a second layer consisting of nickel or a nickel alloy that forms the outer side of the metal housing part.

Abstract: The present invention provides a compound of Formula (I) (represented as tautomers Ia and Ib) or the pharmaceutically acceptable salts thereof, which are KDM5 inhibitors.

Abstract: The disclosure features dexamethasone prodrug dimers of dexamethasone and pharmaceutical compositions thereof useful for, e.g., the extended release of a drug and for the treatment of a disease or condition.

Abstract: The disclosure features dexamethasone prodrug dimers of dexamethasone and pharmaceutical compositions thereof useful for, e.g., the extended release of a drug and for the treatment of a disease or condition.

Abstract: An electrochemical cell includes an annular electrode composite body; and an annular liquid-tight housing formed as a hollow cylinder and including an annular interior space, wherein the housing is arranged around a central aperture or recess, the housing has a height of 5 mm to 40 mm and an external diameter of 6 mm to 20 mm, and the annular electrode composite body is arranged in the annular interior space.

Abstract: Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as arginase inhibitors and can be useful in preventing, treating or acting as a remedial agent for arginase-related diseases.

Abstract: The disclosure relates to compounds and compositions for sustained release of ocular therapeutics.

Abstract: A seatbelt tensioner for a seat belt retractor, having a pipe (1) with a tensioner drive wheel, a gas generator (10), a piston (3), and at least one mass body (4). The mass body (4) is drivable by gas from the gas generator (10) acting on the piston (3) between the gas generator (10) and a mass body (4). The mass body drives the tensioner drive wheel. The pipe (1) has a receiving section (5) with a first inner diameter (2), in which the piston (3) in its initial state is arranged with an initial-state outer diameter (8). The pipe (1) has a guide section (6) which adjoins the receiving section (5) and which has a second inner diameter (7). The second inner diameter (7) is smaller than the first inner diameter (2) and smaller than the initial-state outer diameter (8) of the piston (3).

Abstract: The invention relates to a belt tightener (1) with a mass body drive for a seat belt of a motor vehicle with a force-limiting device with —a belt shaft (3) mounted rotatably in at least one opening (15) of a housing (14) that can be fastened fixedly to the vehicle, it being possible to wind up the seat belt on said shaft, —a tightener drive wheel (24) connected non-rotatably to the belt shaft (3) and having recesses (14) distributed at regular intervals over the circumference, —a chain forming the mass body drive made of loose mass bodies (19), which are guided in a tightener tube (10) and can be driven by pressure application of the tightener tube (10), wherein —the belt shaft (3) can be driven in the winding direction of the seat belt by engagement of the driven mass bodies (19) in the recesses (14) of the tightener drive wheel (24), wherein —the mounting of the belt shaft (3) in the opening (15) of the housing (14) is designed to be flexible in the radial direction.