Abstract: A tool assembly that includes a suction cup that is configured to be removably coupled to a vertical wall and a device for temporarily mounting an article to the suction cup at a desired mounting position and for indicating a position of a hanger on the vertical wall. The hanger is configured to be secured to the vertical wall to mount the article to the vertical wall.

Abstract: A tool for moving an abrasive media can include a tool body and a drive system housed in the tool body. The drive system can include an output member. A retaining member can be disposed on the tool body. A first platen having a first attachment hub can be selectively coupled with the retaining member in an installed position. The first platen can have a first rotatable member that selectively attaches to the output member in a first mode of operation. A second platen having a second attachment hub can selectively couple with the retaining member in an installed position. The second platen can have a second rotatable member that selectively attaches to the output member in a second mode of operation.

Abstract: The present invention provides peptides and supported peptides for treating proliferative diseases. In particularly preferred embodiments, the present invention provides peptides and supported peptides for treating diseases of the skin, such as rosacea. In some particularly preferred embodiments, the supported peptides of the present invention are anti-VEGF peptides. In alternative particularly preferred embodiments, the anti-VEGF peptides are expressed on a scaffold protein. In some most preferred embodiments, the scaffold protein is BBI.

Abstract: The invention is drawn to a novel method useful for screening. In particular, the present invention provides methods for competitive differential screening. In some preferred embodiments, the present invention provides methods for competitive differential screening that facilitate the identification of tight binders. In some preferred embodiments, the agents used in the methods of the present invention comprise tight and weak binders. In other embodiments, the present invention provides methods that utilize competitive binders that recognize and bind targets, but with binding that is less strong than that of binders of interest.

Abstract: A selective targeting method is disclosed comprising contacting a library of ligands, particularly a peptide library, with an anti-target to allow the ligands to bind to the anti-target; separating the non-binding ligands from the anti-target bound ligands, contacting the non-binding anti-target ligands with a target allowing the unbound ligands to bind with the target to form a target-bound ligand complex; separating the target-bound ligand complex from ligands which do not bind to the target, and identifying the target-bound ligands on the target-bound ligand complex wherein the target-bound ligands have a KD in the range of about 10?7 to 10?10 M. Additionally claimed are the ligands identified according to the method.

Abstract: A tool assembly that includes a tool, which has a frame and a pair of suction cups. Each suction cup has a cup housing and a cup structure. The cup housing is coupled to the frame. The cup structure is at least partly received in the cup housing. At least one of the cup structures is rotatable relative to the frame. A method for releasably securing a tool assembly to a wall is also provided.

Abstract: The present application relates to peptides which bind to tannin, polyphenolic or anthocyanin compounds, and particularly to tea and wine stains on a fabric or other surface. The invention also concerns binding peptide conjugates which includes a binding peptide coupled to an agent and the use of the binding peptide conjugate for delivering an agent to a desired target.

Abstract: A tool assembly that includes a tool, which has a frame and a pair of suction cups. Each suction cup has a cup housing and a cup structure. The cup housing is coupled to the frame. The cup structure is at least partly received in the cup housing. At least one of the cup structures is rotatable relative to the frame. A method for releasably securing a tool assembly to a wall is also provided.

Abstract: A tool assembly that includes a tool, which has a frame and a pair of suction cups. Each suction cup has a cup housing and a cup structure. The cup housing is coupled to the frame. The cup structure is at least partly received in the cup housing. At least one of the cup structures is rotatable relative to the frame. A method for releasably securing a tool assembly to a wall is also provided.

Abstract: A tool assembly having: a) a tool, which has a frame, and a pair of suction cups, wherein the suction cups having a cup structure, and wherein at least one of the cup structures is rotatable relative to the frame; and/or b) a rail, a hidden object detector slidably coupled to the rail and a display unit with a display member and a marking unit, wherein the marking unit is configured to form a mark on the display member in response to detection of a hidden object by the hidden object detector; and/or c) a suction cup and a device for mounting an article to the suction cup at a desired position and for indicating a position of a hanger for permanently mounting the article at the desired position.

Abstract: A tool assembly that includes a suction cup that is configured to be removably coupled to a vertical wall and a device for temporarily mounting an article to the suction cup at a desired mounting position and for indicating a position of a hanger on the vertical wall. The hanger is configured to be secured to the vertical wall to mount the article to the vertical wall.

Abstract: A tool for moving an abrasive media can include a tool body and a drive system housed in the tool body. The drive system can include an output member. A retaining member can be disposed on the tool body. A first platen having a first attachment hub can be selectively coupled with the retaining member in an installed position. The first platen can have a first rotatable member that selectively attaches to the output member in a first mode of operation. A second platen having a second attachment hub can selectively couple with the retaining member in an installed position. The second platen can have a second rotatable member that selectively attaches to the output member in a second mode of operation.

Abstract: A tool assembly that includes a tool, which has a frame and a pair of suction cups. Each suction cup has a cup housing and a cup structure. The cup housing is coupled to the frame. The cup structure is at least partly received in the cup housing. At least one of the cup structures is rotatable relative to the frame. A method for releasably securing a tool assembly to a wall is also provided.

Abstract: A tool for moving an abrasive media can include a tool body and a drive system housed in the tool body. The drive system can include an output member. A retaining member can be disposed on the tool body. A first platen having a first attachment hub can be selectively coupled with the retaining member in an installed position. The first platen can have a first rotatable member that selectively attaches to the output member in a first mode of operation. A second platen having a second attachment hub can selectively couple with the retaining member in an installed position. The second platen can have a second rotatable member that selectively attaches to the output member in a second mode of operation.

Abstract: A power tool constructed in accordance to one example of the present teachings can include a housing having a handle and body portion. A motor can be disposed in the body portion and a drive spindle drivingly connected to the motor. A chuck can comprise a chuck spindle that supports a plurality of chuck jaws. A first sleeve can rotationally communicate with the chuck jaws to move the chuck jaws between a clamping position and a non-clamping position. An indicator mechanism can be disposed on the chuck having a first and second visual indicator. The indicator mechanism can move from a first position to a second position upon rotation of the first sleeve to a location that corresponds to a predetermined clamping force attained by the chuck jaws.

Abstract: A tool system with a mount configured to be removably coupled to a surface.

Abstract: The present invention provides peptides and supported peptides for treating various diseases and conditions. In particularly preferred embodiments, the present invention provides compositions and methods for personal care. In some embodiments, the present invention provides compositions for use in skin and/or hair care, as well as cosmetic compositions. In alternative particularly preferred embodiments, the present invention provides peptides and supported peptides for treating diseases of the skin, such as rosacea. In some particularly preferred embodiments, the supported peptides of the present invention are anti-VEGF peptides. In alternative particularly preferred embodiments, the anti-VEGF peptides are expressed on a scaffold protein. In some most preferred embodiments, the scaffold protein comprises BBI.

Abstract: A vacuum can include a housing having an inlet adapted to receive debris being vacuumed. A mounting bar can be fixedly coupled to the housing. A floor collector assembly can be rotatably disposed about a first axis defined by the mounting bar. The floor collector assembly can include a first debris-passing member coupled to the mounting bar, a second debris-passing member rotatably coupled to the first debris-passing member and a third debris-passing member removably coupled to the second debris-passing member. The first debris-passing member can define an opening. The floor collector assembly can be operable in a plurality of modes. In a first mode, the opening can be substantially perpendicular relative to a vacuumed surface. In a second mode, the second debris-passing member can be rotated relative to the first debris-passing member about a second axis such that the opening is at an acute angle relative to the vacuumed surface.