Abstract: Forming an integrated circuit, for example by first, concurrently forming a first front end of line (FEOL) layer having a first thickness and a surface contacting or facing a semiconductor substrate frontside and a second FEOL layer, having a second thickness and including a same material as the first FEOL layer and having a surface contacting or facing a semiconductor substrate backside, and second, processing the second FEOL layer to reduce the second thickness.

Abstract: An inserter for treating glaucoma can comprise a housing, a needle, a plunger, a slider component, and a drive component. The drive component is disposed within a cavity of the housing and rotatable within the cavity to result in movement along a longitudinal axis of the inserter to the needle and the plunger upon rotation of the drive component. The slider component is coupled to the housing and slidable along an elongate groove of the drive component such that movement of the slider component along the axis rotates the drive component within the housing.

Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.

Abstract: Various embodiments of the present disclosure are generally directed to processing conversions of digital assets to fiat currency. An example method includes obtaining a conversion rate for a digital asset via an API, providing the conversion rate via a client device, receiving a digital asset conversion request and executing a digital asset conversion within a configurable time period. Executing the digital asset conversion includes causing digital asset units to be debited from the digital asset user account and causing fiat currency units to be credited to a fiat currency user account. The method further includes dynamically providing a notification of execution of the digital asset conversion via the client device, updating account balance data objects associated with the digital asset user account and the fiat currency user account, and subsequent to executing the digital asset conversion, executing a fiat currency transaction (e.g., a settlement) with a digital asset exchange system.

Abstract: A mask system for delivery of respiratory therapy to a patient includes a nares portion and a mouth portion and an inlet conduit connected to at least one of the nares portion and the mouth portion to deliver the pressurized, breathable gas. The mask system is adapted to selectively utilize the nares portion and/or the mouth portion in a first mode utilizing both the nares portion and the mouth portion, and in a second mode utilizing the nares portion and not utilizing the mouth portion.

Abstract: A system for wireless power transmission, preferably including one or more power transmitters, detectors, and/or processing modules, and optionally including one or more power receivers and/or auxiliary sensors. A method for field detection, preferably including transmitting power, receiving latent scattering signals, analyzing the scattering signals, and/or acting based on the analysis.

Abstract: Compounds and compositions are disclosed in which a NAMPT Drug Unit is conjugated to a targeting Ligand Unit through quaternization by a Linker Unit from which a NAMPT inhibitor compound or derivative thereof is released at the targeted site of action. Methods for treating diseases characterized by the targeted abnormal cells, such as those of cancer or an autoimmune disease, using the compounds and compositions of the invention are also disclosed.

Abstract: Systems for off-axis a vertebral body. A steerable assembly includes a steering instrument, a steering handle, and a trigger. A deflectable portion of the steering instrument and a distal portion of a deformable conduit are configured to be directed through and beyond the access cannula. A control surface of the trigger is configured to receive a pull or squeeze input to pivot the trigger to move the steering instrument to an operating mode in which increased tension on the steering instrument curves the deflectable portion of the steering instrument and the distal portion of the deformable conduit. A mounting block may be fixed within the steering handle, and a proximal end of the shaft may be fixed to the mounting block. The steering handle includes a guide movably supported within a void and coupled to the control element. A rear surface of the trigger engages the guide.

Abstract: Systems and methods for augmenting a vertebral body. An introducer device includes a shaft having a flexible distal portion with a pre-set curve in an unconstrained state. An input provided to an actuator to tension a pulling element to move the pre-set curve to a constrained state in which the distal portion and a flexible sheath conforming to the shaft at least partially straighten. The introducer device is removable from the sheath remaining offset from a longitudinal axis. A spacer hub facilitates proximal movement of the sheath relative to an access cannula expose a balloon through a syringe-style input. A hub of the access cannula may be adjustable to selectively adjust an interference surface relative to a datum. At least two radiopaque markers may be disposed on the sheath with relative positions between the markers viewable on lateral and A-P radiography to determine the location and/or curvature of the sheath.

Abstract: Apparatus for generating a supply of air at positive pressure for the amelioration or treatment of a respiratory disorder includes a first chamber, a second chamber, at least one inlet tube structured and configured to allow ambient air to enter the first chamber, at least one flow tube structured and configured to allow air to pass from the first chamber to the second chamber, and a blower structured and configured to produce a flow of air at positive pressure. The blower is positioned in the first chamber and structured and configured to receive air from the second chamber. The blower includes a housing structured and configured to sealingly separate air flow through an interior of the housing from the first chamber. The at least one inlet tube is axially spaced from the at least one flow tube.

Abstract: A video game includes a single player mode where completion of storyline objectives advances the single player storyline. The video game also includes a multiplayer mode where a plurality of players can play on an instance of a multiplayer map. Storyline objectives from the single player mode are selected and made available for completion to players in the multiplayer mode, and the single player storylines can be advanced by players completing respective storyline objectives while playing in the multiplayer mode. Combinations of storyline objectives are selected from pending storyline objectives for players connecting to a multiplayer game for compatibility with multiplayer maps. Constraints can be used to determine compatibility.

Abstract: A funnel-less filtration device that attaches directly to a storage container such as a cell culture media bottle. The device includes a filter collar containing one or more membranes, an inlet with a coupling device for attaching the filter device to a supply of liquid to be filtered, an outlet at a lower portion of the collar, a vacuum port in the collar below the membrane(s) and a filtered vent in the collar above the membrane(s). Optionally, the device may include a filtrate reservoir attached to the outlet, preferably by a threaded connection. Optionally, the upper opening to the filter collar is selectively and removably sealed with a lid until used. The lid is then removed the filter device inverted over a storage container such as cell culture media bottle and the two are attached via the upper opening of the filter collar. The assembly is then inverted so the supply container is above the filter device.

Abstract: A display system comprising a steerable display having a monocular field of view of at least 1 degree, positioned within a scannable field of view of at least 20 degrees, the steerable display positioned for a user. In one embodiment, the steerable display is positioned for the user's fovea.

Abstract: Computing architectures, platforms, and systems are provided herein. In one example, system is provided. The system includes a management processor configured to initiate a communication arrangement between a first endpoint device coupled to a communication fabric and a second endpoint device coupled to the communication fabric. The communication arrangement is configured to redirect a transfer from the first endpoint device based on an address corresponding to an address range of the second endpoint device without passing the transfer through a host processor coupled to the communication fabric that executes an application initiating the transfer.

Abstract: Systems and methods for providing an electronics module including a raceway for mounting submodules and establishing electrical communication with said submodules. The raceway comprises a base structure and a conductive trace formed by a conductive plating process. Connection pads on the raceway are configured to receive connection nodes of the submodules for providing a continuous electrical connection between the raceway and the submodules for electrical communication and power transmission.

Abstract: Communication fabric-coupled computing architectures, platforms, and systems are provided herein. In one example, an apparatus includes a management entity configured to establish a compute unit comprising components from among a plurality of physical computing components by at least instructing a communication fabric communicatively coupling the plurality of physical computing components to establish logical isolation within the communication fabric to form the compute unit. Responsive to an indication of a change in workload associated with at least a software component deployed to a processing element of the compute unit, the management entity is configured to adjust the logical isolation to alter a quantity of the plurality of physical computing components in the compute unit in accordance with the change in the workload.

Abstract: A pre-pack assembly for use with an air gun and for use with a magazine that is removably insertable into the air gun, the pre-pack assembly includes a pre-pack that contains a gas canister, wherein inserting the pre-pack into the chamber of the magazine fluidly connects the gas canister with the magazine.

Abstract: Disclosed are example embodiments of systems, method, and devices for generating audio assets. The example method includes receiving an input including at least one of audio, text, video, Java Script Object Notation (JSON), Extensible Markup Language (XML), Really Simple Syndication (RSS). The example method includes receiving configuration inputs including at least one of configure language, gender, and persona. The example method includes preparing for processing based on the at least one of configure language, gender, and persona. The example method includes processing the input based on the configuration inputs, the processing including at least one of transcribing, translating, brand safety, enrichment, generating custom Speech Synthesis Markup Language (SSML), and including generating an audio clip. The example method includes delivering the audio clip.

Abstract: A fluid end for use with a power end. The fluid end comprises a plurality of fluid end sections positioned adjacent one another. Each section includes a single horizontally positioned bore. A plunger is installed within the bore and includes a fluid passageway. Low-pressure fluid enters the bore through the plunger and high-pressure fluid exits the fluid end through an outlet valve installed within the bore. The intake of low-pressure fluid within the fluid end section is regulated by an inlet valve installed within the plunger. Low-pressure fluid enters the plunger through an inlet component attached to both the plunger and an inlet manifold.

Abstract: Apparatuses, methods, and systems are disclosed for accelerated ergonomic collection of capillary blood. An apparatus and system include a blood collection module with a proximal portion including a vacuum generation chamber, a distal portion including a blood collection chamber, a concave mid portion including a pressure equalization channel configured to equalize reduced air pressure. The apparatus further includes a sealing surface to stably seal the blood collection module to the skin around a collection site and a slide latch actuated by a lengthwise sliding motion. Also included is a lancet carrier with linearly-arranged lancet strips to puncture rows of blood extraction slits in the collection site. The apparatus also includes an angled transfer port with a low-resistance non-microfluidic blood flow channel to a transfer module, then to a plasma separation module with a multilayer laminate and plasma separation membrane. Methods for accelerated ergonomic collection of capillary blood are disclosed.