Abstract: The current disclosure describes a new vertical tunnel field-effect transistor (TFET). The TFET includes a source layer over a substrate. A first channel layer is formed over the source layer. A drain layer is stacked over the first channel layer with a second channel layer stacked therebetween. The drain layer and the second channel layer overlap a first surface portion of the first channel layer. A gate structure is positioned over the channel layer by a second surface portion of the channel layer and contacts a sidewall of the second channel layer.

Abstract: A lithography-free, mold-free method of fabricating high quality optical material by curing polydimethylsiloxane (PDMS) droplets in or on pre-heated substrates allows lenses with different focal lengths to be made by varying the volume and surface temperature, as well as the substrate.

Abstract: A disposable patient isolation hood is provided and includes a frame and an isolation element, wherein the frame includes a base and a support bridge, and two ends of the support bridge are respectively connected to the first end portion and the second end portion of the base. The isolation element is flexible, and at least a part thereof is made of a transparent material. The isolation element is arranged to cover the support bridge to form a space that can encompass at least a part of the subject in need. The disposable patient isolation hood is easy to carry and has high mobility, so that medical practitioners can be isolated and protected during medical treatment of patients even in the absence of medical resources or in emergency situations.

Abstract: Compounds of Formula (I) shown below and a pharmaceutical composition containing one of the compounds: Each of the variables is defined herein. Also disclosed is a method of treating a condition associated with uncontrolled cell growth with a compound of Formula (I).

Abstract: The present disclosure relates to the fabrication and characterization of an optical fiber capable of firing light virtually from any point along its circumferential surface. The optical fiber is preferably prepared by laser micromachining. In preferred embodiments, laser radiation is focused onto a multimode optical fiber axis, forming a conical-shaped cavity (side window) in the fiber core. Because of the total internal reflection when the laser beam reaches the side window-outside medium interface, the beam is reflected to the side of the optical fiber.

Abstract: An isolated antibody, comprising a light-chain CDR1 (L-CDR1) having the sequence of SEQ ID NO: 1, SEQ ID NO: 7, or SEQ ID NO: 14; a light-chain CDR2 (L-CDR2) having the sequence of SEQ ID NO: 2 or SEQ ID NO: 15; a light-chain CDR3 (L-CDR3) having the sequence of SEQ ID NO: 3, SEQ ID NO: 8, SEQ ID NO: 21, or SEQ ID NO: 24; a heavy-chain CDR1 (H-CDR1) having the sequence of SEQ ID NO: 4, SEQ ID NO: 9, SEQ ID NO: 11, SEQ ID NO: 16, or SEQ ID NO: 25; a heavy-chain CDR2 (H-CDR2) having the sequence of SEQ ID NO: 5, SEQ ID NO: 12, SEQ ID NO: 17, SEQ ID NO: 19, SEQ ID NO: 22, or SEQ ID NO: 26; and a heavy-chain CDR3 (H-CDR3) having the sequence of SEQ ID NO: 6, SEQ ID NO: 10, SEQ ID NO: 13, SEQ ID NO: 18, SEQ ID NO: 20, SEQ ID NO: 23, or SEQ ID NO: 27, wherein the antibody specifically binds to A?1-42 or an N-terminal modified form thereof.

Abstract: An isolated antibody, comprising: heavy chain complementary determining regions CDR1, CDR2, and CDR3 of a heavy chain variable region sequence selected from SEQ ID NOs: 2, 6, 10, and 14; and light chain complementary determining regions CDR1, CDR2, and CDR3 of a light chain variable region sequence selected from SEQ ID NOs: 4, 8, 12, and 16; wherein the antibody binds specifically to a RSPO3 protein.

Abstract: Embodiments provide data in-flight (DIF) services to software applications such as virtual machines (VMs) at an application level without requiring modification to established storage protocols. In exemplary embodiments, a storage controller transmits an advertisement of one or more data in-flight (DIF) services supported by a storage container of the storage controller. One or more DIF services communication path is created with attributes corresponding to the DIF services supported by the storage container. The storage controller receives, over the DIF services communication path, tagged data that can include data transmitted by a virtual machine (VM) for storage in the storage container.

Abstract: An operating circuit including a system circuit and a power control circuit is provided. The system circuit operates according to the voltage of the node. The power control circuit includes a first connection port, a second connection port, a first always-on switch, a second always-on switch, a first current limiter, and a second current limiter. The first connection port is configured to receive first power provided by a first external device. The second connection port is configured to receive second power provided by a second external device. The first always-on switch is coupled to the first connection port to transmit the first power. The second always-on switch is coupled to the second connection port to transmit the second power. The first current limiter is coupled between the first always-on switch and the node. The second current limiter is coupled between the second always-on switch and the node.

Abstract: A methodology for assays and diagnostics utilizes a nanoporous or corrugated metal-containing surface, fiber or particle which enhances or suppresses the optical detectability of a label. The resulting optical, electromagnetic, or imaging signal signals the presence of a pathogen or analyte of interest. Preferred embodiments pertain to label-free, in situ monitoring of individual DNA hybridization in microfluidics using molecular sentinel probes immobilized on nanoporous gold disks. By immobilizing molecular sentinel probes on nanoporous gold disks, single-molecule sensitivity is demonstrated via surface-enhanced Raman scattering which provides robust signals. The described methodology is generally applicable to most amplification independent assays and molecular diagnostics.

Abstract: A virtualization platform can discover capabilities of data devices connected in a virtual infrastructure. The virtualization platform allows a user (e.g., system administrator) to specify a policy profile for a virtual machine in terms of performance and data handling parameters. The virtualization platform can provision a virtual machine comprising data devices having a combined capability that matches the policy profile. Enforcement of a policy profile can be made when I/O is performed by a virtual machine.

Abstract: Heterocyclic compounds of Formula (I) shown herein. Also disclosed is a pharmaceutical composition containing one of the heterocyclic compounds. Further disclosed are methods of using one of the heterocyclic compounds for mobilizing hematopoietic stem cells and endothelial progenitor cells into the peripheral circulation, and for treating tissue injury, cancer, inflammatory disease, and autoimmune disease.

Abstract: Embodiments perform capability discovery, policy management, and policy enforcement to provide data in-flight (DIF) services to virtual machines (VMs) without requiring modification to established storage protocols. In exemplary embodiments, a management device receives advertisements of DIF services supported by network nodes. The management device groups the advertised DIF services into a DIF services policy. The management device associates a host and a communication path. The management device enforces the DIF services policy by storing a unique number that causes transmission of data along the communication path.

Abstract: A nanoporous metal can be formed by projecting laser patterns using a spatial light modulator (SLM) onto a gold/silver alloy film immersed in diluted nitric acid solutions. Heat accumulation induced by the photothermal effect enables localized dealloying in dilute nitric acid. NPG micropatterns can be formed at the irradiated spots while the surrounding alloy remains intact.

Abstract: An optrode may provide a cylindrical substrate with two or more electrodes deposited on said cylindrical substrate. The cylindrical substrate and electrodes may be coated by an insulating layer with openings or vias over certain portions of the electrodes that may provide a contact for the neural probe or may be utilized to connect lead lines. Manufacturing of an optrode may utilize a jig that secures a cylindrical substrate coated by a conductive material and a resist. A first mask may be positioned in an opening provided by the jig, and the cylindrical substrate may expose ions or neutral particles to define one or more electrode patterns. After regions of the resist and conductive material are removed to form the electrodes, a second mask may be utilized to define via regions in which portions of the electrodes are exposed and uncoated by an insulating layer.

Abstract: A nanoporous gold disk (NPGD) as a novel surface-enhanced Raman spectroscopy (SERS) substrate. NPGD has SERS enhancement factor similar to that of gold nanoshells, but allows, for example, at least three times more benzenethiol molecules to be attached to its surface due to large surface-to-volume ratio. The high capacity enables the rapid detection of attomole-level benzenethiol molecules with relatively high detector temperatures. Additionally, a fabrication process to make NPGD with controlled size and highly reproducible SERS activities.

Abstract: A lithography-free, mold-free method of fabricating high quality optical material by curing polydimethylsiloxane (PDMS) droplets in or on pre-heated substrates allows lenses with different focal lengths to be made by varying the volume and surface temperature, as well as the substrate.

Abstract: A lithography-free, mold-free method of fabricating high quality optical material by curing polydimethylsiloxane (PDMS) droplets in or on pre-heated substrates allows lenses with different focal lengths to be made by varying the volume and surface temperature, as well as the substrate.

Abstract: The present disclosure relates to the fabrication and characterization of an optical fiber capable of firing light virtually from any point along its circumferential surface. The optical fiber is preferably prepared by laser micromachining. In preferred embodiments, laser radiation is focused onto a multimode optical fiber axis, forming a conical-shaped cavity (side window) in the fiber core. Because of the total internal reflection when the laser beam reaches the side window-outside medium interface, the beam is reflected to the side of the optical fiber.

Abstract: The current disclosure describes a new vertical tunnel field-effect transistor (TFET). The TFET includes a source layer over a substrate. A first channel layer is formed over the source layer. A drain layer is stacked over the first channel layer with a second channel layer stacked therebetween. The drain layer and the second channel layer overlap a first surface portion of the first channel layer. A gate structure is positioned over the channel layer by a second surface portion of the channel layer and contacts a sidewall of the second channel layer.