Patents by Inventor Colin Mitchinson

Colin Mitchinson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR REDUCING VISCOSITY IN SACCHARIFICATION PROCESS
    Publication number: 20190249160
    Abstract: The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity, methods for hydrolyzing biomass material, and methods for reducing viscosity of biomass mixture using a composition comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity.
    Type: Application
    Filed: December 10, 2018
    Publication date: August 15, 2019
    Inventors: COLIN MITCHINSON, MIAN LI, BRADLEY R. KELEMEN, SUZANNE E. LANTZ, KEITH D. WING, WILLIAM D. HITZ
  • NOVEL GLYCOSYL HYDROLASE ENZYMES AND USES THEREOF
    Publication number: 20190169585
    Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.
    Type: Application
    Filed: February 14, 2019
    Publication date: June 6, 2019
    Inventors: Benjamin Bower, Mark Emptage, William D. Hitz, Megan Yee Hsi, Thijs Kaper, Bradley R. Kelemen, Steven Kim, Suzanne E. Lantz, Edmund A. Larenas, Colin Mitchinson, Keith Dumont Wing
  • METHODS FOR IMPROVING THE EFFICIENCY OF SIMULTANEOUS SACCHARIFICATION AND FERMENTATION REACTIONS
    Publication number: 20190161772
    Abstract: The present disclosure is directed, in a first aspect, to the use of inverting beta-xylosidase enzymes to reduce byproduct formation and increase the yield of fermentation products, as well as, in a second aspect, to the use of retaining beta-xylosidase enzymes to improve production of alkyl-beta-xylopyranoside compounds, in a simultaneous saccharification and fermentation reactions.
    Type: Application
    Filed: September 18, 2018
    Publication date: May 30, 2019
    Inventors: CHRISTINA GUTIERREZ, Colin Mitchinson, Tom T. Huang, Bruce A. Diner, Paul Joseph Fagan, William D. Hitz
  • METHOD FOR IMPROVING YIELD OF CELLULOSE CONVERSION PROCESSES
    Publication number: 20190153493
    Abstract: The present teachings provide methods of converting cellulosic materials to soluble sugars. Methods for increasing the yield of glucose from the enzymatic saccharification of cellulosic materials is also provided. The present teachings further provide methods of increasing the yield of cellobiose from the enzymatic saccharification of cellulosic materials.
    Type: Application
    Filed: January 28, 2019
    Publication date: May 23, 2019
    Inventors: Bradley R. Kelemen, Colin MITCHINSON, Edmund A. LARENAS
  • Glycosyl hydrolase enzymes and uses thereof
    Patent number: 10273465
    Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.
    Type: Grant
    Filed: July 27, 2015
    Date of Patent: April 30, 2019
    Assignee: DANISCO US INC.
    Inventors: Benjamin Bower, Megan Yee Hsi, Thijs Kaper, Bradley R. Kelemen, Suzanne E. Lantz, Edmund A. Larenas, Colin Mitchinson, Steven Kim, William D. Hitz, Mark Emptage, Keith Dumont Wing
  • Method for reducing viscosity in saccharification process
    Patent number: 10190108
    Abstract: The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity, methods for hydrolyzing biomass material, and methods for reducing viscosity of biomass mixture using a composition comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity.
    Type: Grant
    Filed: August 6, 2015
    Date of Patent: January 29, 2019
    Assignee: DANISCO US INC.
    Inventors: Colin Mitchinson, Mian Li, Bradley R. Kelemen, Suzanne E. Lantz, Keith D. Wing, William D. Hitz
  • Methods for improving the efficiency of simultaneous saccharification and fermentation reactions
    Patent number: 10138499
    Abstract: The present disclosure is directed, in a first aspect, to the use of inverting beta-xylosidase enzymes to reduce byproduct formation and increase the yield of fermentation products, as well as, in a second aspect, to the use of retaining beta-xylosidase enzymes to improve production of alkyl-beta-xylopyranoside compounds, in a simultaneous saccharification and fermentation reactions.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: November 27, 2018
    Assignee: DANISCO US INC.
    Inventors: Christina Gutierrez, Colin Mitchinson, Tom T. Huang, Bruce A. Diner, Paul Joseph Fagan, William D. Hitz
  • GLYCOSYL HYDROLASE ENZYMES AND USES THEREOF FOR BIOMASS HYDROLYSIS
    Publication number: 20180163242
    Abstract: The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having glycosyl hydrolase (GH) family 61/endoglucanase activity and/or a ?-glucosidase polypeptide, methods for hydrolyzing biomass material, and methods for using such compositions.
    Type: Application
    Filed: July 12, 2017
    Publication date: June 14, 2018
    Inventors: COLIN MITCHINSON, MEREDITH K. FUJDALA, WILLIAM D. HITZ, MEGAN Y. HSI, STEVEN S. KIM, KEITH D. WING
  • INDUCTION OF GENE EXPRESSION USING A HIGH CONCENTRATION SUGAR MIXTURE
    Publication number: 20180148683
    Abstract: Described herein is a composition useful for inducing expression of genes whose expression is under control of an inducible promoter sequence and methods for the compositions preparation and use.
    Type: Application
    Filed: July 7, 2016
    Publication date: May 31, 2018
    Applicant: DANISCO US INC.
    Inventors: Timothy C. DODGE, Ilkka Ilari KRUUS, Colin MITCHINSON, Timo Tapio VILJAVA
  • Variant CBH1 cellulases
    Patent number: 9896674
    Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: February 20, 2018
    Assignee: DANISCO US INC
    Inventors: Anthony Day, Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Paulien Neefe, Mats Sandgren, Andrew Shaw, Jerry Stahlberg
  • Variant CBH1.1
    Patent number: 9644192
    Abstract: Disclosed are variants of Humicola grisea CeI7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: May 9, 2017
    Assignee: Danisco US Inc., Genencor Division
    Inventors: Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Edmund Larenas
  • METHOD FOR IMPROVING YIELD OF CELLULOSE CONVERSION PROCESSES
    Publication number: 20170107548
    Abstract: The present teachings provide methods of converting cellulosic materials to soluble sugars. Methods for increasing the yield of glucose from the enzymatic saccharification of cellulosic materials is also provided. The present teachings further provide methods of increasing the yield of cellobiose from the enzymatic saccharification of cellulosic materials.
    Type: Application
    Filed: September 9, 2016
    Publication date: April 20, 2017
    Applicant: DANISCO US INC.
    Inventors: Bradley R. KELEMEN, Edmund A. LARENAS, Colin MITCHINSON
  • METHOD FOR REDUCING VISCOSITY IN SACCHARIFICATION PROCESS
    Publication number: 20170096651
    Abstract: The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity, methods for hydrolyzing biomass material, and methods for reducing viscosity of biomass mixture using a composition comprising a polypeptide having glycosyl hydrolase family 61/endoglucanase activity.
    Type: Application
    Filed: August 6, 2015
    Publication date: April 6, 2017
    Applicant: DANISCO US INC.
    Inventors: Colin MITCHINSON, Mian LI, Bradley R. KELEMEN, Suzanne E. LANTZ, Keith D. WING, William D. HITZ
  • NOVEL VARIANT HYPROCREA JECORINA CBH1 CELLULASES
    Publication number: 20160312202
    Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
    Type: Application
    Filed: January 21, 2016
    Publication date: October 27, 2016
    Inventors: Anthony DAY, Frits GOEDEGEBUUR, Peter GUALFETTI, Colin MITCHINSON, Paulien NEEFE, Mats SANDGREN, Andrew SHAW, Jerry STAHLBERG
  • NOVEL GLYCOSYL HYDROLASE ENZYMES AND USES THEREOF
    Publication number: 20160177279
    Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.
    Type: Application
    Filed: July 27, 2015
    Publication date: June 23, 2016
    Applicant: DANISCO US INC.
    Inventors: Benjamin BOWER, Megan Yee HSI, Thijs KAPER, Bradley R. KELEMEN, Suzanne E. LANTZ, Edmund A. LARENAS, Colin MITCHINSON, Steven KIM, William D. HITZ, Mark EMPTAGE, Keith Dumont WING
  • Induction of gene expression using a high concentration sugar mixture
    Patent number: 9034628
    Abstract: Described herein is a composition useful for inducing expression of genes whose expression is under control of an inducible promoter sequence and methods for the compositions preparation and use.
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: May 19, 2015
    Assignee: Danisco US Inc.
    Inventors: George R. England, Aaron Kelley, Colin Mitchinson
  • VARIANT HUMICOLA GRISEA CBH1.1
    Publication number: 20150079638
    Abstract: Disclosed are variants of Humicola grisea CeI7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
    Type: Application
    Filed: August 20, 2014
    Publication date: March 19, 2015
    Applicant: Danisco US Inc.
    Inventors: Frits GOEDEGEBUUR, Peter Gualfetti, Colin Mitchinson, Edmund Larenas
  • NOVEL VARIANT HYPOCREA JECORINA CBH1 CELLULASE
    Publication number: 20140302584
    Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
    Type: Application
    Filed: February 25, 2014
    Publication date: October 9, 2014
    Applicant: DANISCO US INC.
    Inventors: Anthony DAY, Frits GOEDEGEBUUR, Peter GUALFETTI, Colin MITCHINSON, Paulien NEEFE, Mats SANDGREN, Andrew SHAW, Jerry STAHLBERG
  • METHODS AND COMPOSITIONS FOR ENHANCED PRODUCTION OF ORGANIC SUBSTANCES FROM FERMENTING MICROORGANISMS
    Publication number: 20140287473
    Abstract: The present invention relates methods and compositions for producing an organic substance from fermenting microorganism using simultaneous saccharification and fermentation. One aspect of the invention provides producing alcohol by simultaneous saccharification and fermentation by combining a cellulosic substrate, and whole fermentation broth, and an ethanologenic microorganism under conditions conducive both to hydrolysis of cellulose to glucose and to conversion of glucose to alcohol.
    Type: Application
    Filed: March 22, 2013
    Publication date: September 25, 2014
    Applicant: DANISCO US INC.
    Inventors: Mian Li, Colin Mitchinson, Landon M. Steele
  • Variant humicola grisea CBH1.1
    Patent number: 8828702
    Abstract: Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: September 9, 2014
    Assignee: Danisco US Inc.
    Inventors: Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Edmund Larenas