Abstract: An enhanced haptic feedback system for medical diagnostics includes a laparoscope configured to be inserted into a body cavity to view tissue and obtain an image of the viewed tissue. An imaging device is configured to acquire physiological data about tissue, process the acquired physiological data, and output the processed data to a graphical user haptic interface (GUHI) capable of generating tangible sensations utilizing one or more haptic interfaces. The GUHI is configured to combine the image received from the laparoscope and the processed physiological data received from the imaging device to provide tangible sensations on both a front screen of the GUHI and a rear screen of the GUHI allowing a surgeon the sensation of feeling for abnormal tissue conditions between the surgeon's hands.

Abstract: A surgical instrument includes a housing, a shaft extending distally from the housing, an end effector assembly disposed at a distal end of the shaft, a knife slidably disposed within the shaft, a movable handle operably coupled to the housing, a trigger operably coupled to the housing, a drive assembly operably coupled between the movable handle and the end effector assembly such that movement of the movable handle manipulates the end effector assembly, and a linkage operably coupled between the trigger and the knife such that movement of the trigger deploys the knife. In an initial position of the movable handle, a portion of a drive housing of the drive assembly intersects a path of movement of the linkage to inhibit movement of the linkage, thereby inhibiting actuation of the trigger.

Abstract: Oligonucleotide primers and methods of use in producing sequencing libraries are provided according to aspects of the present disclosure which include, from 5? to 3?, a homopolymer-hybridizing region, and an anchor region comprising 5?-(?)nNm-3?, wherein the homopolymer-hybridizing region is a contiguous sequence of 5 to 20 elements, wherein the elements are nucleotides or Tm increasing nucleotide analogs, wherein at least 4 of the elements are Tm increasing nucleotide analogs, wherein the homopolymer-hybridizing region hybridizes to a complementary homopolymer tract of a target nucleic acid, wherein the complementary homopolymer tract comprises a contiguous sequence of complementary elements, wherein ? is any nucleotide or nucleotide analog with the proviso that ? is not a nucleotide or nucleotide analog complementary to a complementary element of the complementary homopolymer tract, and wherein N is any nucleotide or nucleotide analog.

Abstract: A surgical instrument includes a housing, a shaft extending distally from the housing, an end effector disposed at a distal end of the shaft, an actuator operably coupled to the housing, an actuation assembly, and a sensor module. The actuation assembly extends through the housing and the shaft and includes a distal end operably coupled to the end effector or a component associated therewith, a proximal end operably coupled to the actuator, and a spring. Actuation of the actuator manipulates the end effector or deploys the component relative thereto. The sensor module is disposed within the housing and configured to sense a property of the spring indicative of an amount the spring has been compressed. The sensor module is further configured, based upon the sensed property, to determine a condition of the end effector or the relative position of the component.

Abstract: A colpotomy system includes a colpotomy cup that extends to a distal surface and defines a longitudinal axis. The colpotomy system further includes a cutter operably coupled to the colpotomy cup and configured to travel along an arcuate path defined about the distal surface of the colpotomy cup. The cutter actuatable to separate a uterus from a vagina as the cutter rotates about the longitudinal axis of the colpotomy cup.

Abstract: A forceps includes a shaft defining first opposed distal recesses, a drive bar slidably disposed within the shaft and defining second opposed distal recesses, and an end effector assembly including first and second jaw members. Each jaw member defines a proximal flange and a distal jaw body. The proximal flanges each define an aperture and a cam slot. A pivot pin extends through the apertures with ends of the pivot pin extending outwardly from the jaw members to be at least partially disposed within the first recesses and fixedly engaged therewith. A drive pin extends through the cam slots with ends of the drive pin extending outwardly from the jaw members to be at least partially disposed within the second recesses and fixedly engaged therewith such that translation of the drive bar relative to the end effector assembly pivots the jaw members between spaced-apart and approximated positions.

Abstract: The present invention encompasses polymer compositions comprising aliphatic polycarbonate chains containing functional groups that increase the polymer's ability to wet or adhere to inorganic materials. In certain embodiments, chain ends of the aliphatic polycarbonates are modified to introduce silicon-containing functional groups, boron-containing functional groups, phosphorous-containing functional groups, sulfonic acid groups or carboxylic acid groups.

Abstract: A thermal cutting element for a surgical instrument includes a substrate, a Plasma Electrolytic Oxidation (PEO) coating disposed on the substrate, and a heating element disposed on the PEO coating and including first and second end portions adapted to connect to different potentials of electrical energy to heat the heating element. A jaw member of a surgical instrument includes a structural frame including a proximal flange portion and a distal body portion, a jaw housing surrounding the distal body portion of the structural frame, a tissue-treating plate disposed atop the jaw housing and defining a longitudinal slot therethrough along at least a portion of a length thereof, and the thermal cutting element disposed within the longitudinal slot.

Abstract: A system and method for automatically generating a narrative story receives data and information pertaining to a domain event. The received data and information and/or one or more derived features are then used to identify a plurality of angles for the narrative story. The plurality of angles is then filtered, for example through use of parameters that specify a focus for the narrative story, length of the narrative story, etc. Points associated with the filtered plurality of angles are then assembled and the narrative story is rendered using the filtered plurality of angles and the assembled points.

Abstract: A method of manufacturing a thermal cutting element for a surgical instrument includes manufacturing a substrate, coating at least a portion of the substrate via Plasma Electrolytic Oxidation (PEO), and disposing a heating element on at least a portion of the PEO-coated substrate. The method may further include attaching the thermal cutting element to a jaw member of a surgical instrument.

Abstract: An energy generator includes a connector port configured to couple to an electrosurgical instrument including an electrode having a polymeric dielectric coating; a power converter configured to generate energy; and a sensor coupled to the power converter and configured to sense a parameter of the energy. The energy generator also includes a controller coupled to the sensor and the power converter. The controller is configured to: control the power converter to output energy to modify an electrical property of the polymeric dielectric coating; and determine whether the electrical property of the polymeric dielectric coating has been sufficiently modified by the energy.

Abstract: A surgical instrument is provided and includes a housing having a shaft. An end effector assembly is operatively connected to a distal end of the shaft and has a pair of first and second jaw members that are movable relative to one another. A drive assembly operably couples to a handle assembly associated with the housing and is configured to impart movement of a respective jaw member when the handle assembly is actuated. A spring component operably associated with each of the jaw members is configured to provide a sealing force at the jaw members.

Abstract: In one aspect, the present disclosure encompasses polymerization systems for the copolymerization of CO2 and epoxides comprising 1) a catalyst including a metal coordination compound having a permanent ligand set and at least one ligand that is a polymerization initiator, and 2) a chain transfer agent having two or more sites that can initiate polymerization. In a second aspect, the present disclosure encompasses methods for the synthesis of polycarbonate polyols using the inventive polymerization systems. In a third aspect, the present disclosure encompasses polycarbonate polyol compositions characterized in that the polymer chains have a high percentage of —OH end groups and a high percentage of carbonate linkages. The compositions are further characterized in that they contain polymer chains having an embedded polyfunctional moiety linked to a plurality of individual polycarbonate chains.

Abstract: The present invention provides nanofiltration membranes with reduced chemical reactivity that can be utilized in manufacturing processes where reactive feedstocks and/or products are utilized or produced. Methods of making and using the membranes are also provided.

Abstract: A dynamically reconfigurable insurance product, system, and computer-implemented method may, with customer permission or consent, collect customer data; analyze the customer data to determine life events, and customer location and activities; and dynamically adjust the insurance product in real-time or substantially real-time. The dynamically reconfigurable insurance product may include several types of insurance, such as auto, home, life, personal articles, etc. From the data collected, risk levels associated with the insured, their family, and/or personal belongings may be adjusted. Based upon the risk levels determined, different types of the insurance within the insurance product may be updated, or new types of insurance may be added to the insurance product. For instance, based upon a marriage or birth of a child, life insurance coverage may be added or increased. The customer may then be notified of the changes, or proposed changes, and approve or reject the changes to the insurance product.

Abstract: Disclosed are high strength polyurethane foam compositions and methods of making them. In one aspect, the inventive polyurethane foams include strength enhancing additives comprising one or more polycarbonate polyols derived from the copolymerization of CO2 and one or more epoxides. In one aspect, the inventive methods include the step of substituting a portion of the polyether polyol in the B-side of a foam formulation with one or more polycarbonate polyols derived from the copolymerization of CO2 and one or more epoxides.

Abstract: A surgical instrument includes a housing, a shaft extending distally from the housing, an end effector assembly disposed at a distal end of the shaft, a knife slidably disposed within the shaft, a movable handle operably coupled to the housing, a trigger operably coupled to the housing, a drive assembly operably coupled between the movable handle and the end effector assembly such that movement of the movable handle manipulates the end effector assembly, and a linkage operably coupled between the trigger and the knife such that movement of the trigger deploys the knife. In an initial position of the movable handle, a portion of a drive housing of the drive assembly intersects a path of movement of the linkage to inhibit movement of the linkage, thereby inhibiting actuation of the trigger.

Abstract: The present invention encompasses polyurethane compositions comprising aliphatic polycarbonate chains. In one aspect, the present invention encompasses polyurethane foams, thermoplastics and elastomers derived from aliphatic polycarbonate polyols and polyisocyanates wherein the polyol chains contain a primary repeating unit having a structure: In another aspect, the invention provides articles comprising the inventive foam and elastomer compositions as well as methods of making such compositions.

Abstract: A method for managing focus in a graphical user interface using a directional controller that allows a directional or selection input. The method comprising: determining whether the input is directional or selection; determining whether there is a sibling object of a currently focused object in a given direction of the input if the input is directional; transferring the focus to the sibling object if there is a sibling object in the given direction; transferring the focus to an ancestor object of the currently focused object if there is no sibling object in the given direction; determining whether the currently focused object is a group; transferring the focus to a descendant object of the currently focused object if the currently focused object is a group and the input is selection; and selecting the currently focused object if the currently focused object is not a group and the input is selection.

Abstract: Methods, system, and kits are provided for sample identification, and, more specifically, for designing, and/or making, and/or using sample discriminating codes or barcodes for identifying sample nucleic acids or other biomolecules or polymers. For example, a plurality of flowspace codewords may be generated, the codewords comprising a string of characters. A location for at least one padding character within the flowspace codewords may be determined. The padding character may be inserted into the flowspace codewords at the determined location. After the inserting, a plurality of the flowspace codewords may be selected based on satisfying a predetermined minimum distance criteria, wherein the selected codewords correspond to valid base space sequences according to a predetermined flow order. And the barcode sequences corresponding to the selected codewords may be manufactured.