Abstract: A vessel sealing instrument includes a housing having a shaft extending from a distal end thereof having an end effector assembly including a pair of opposing first and second jaw members operably coupled thereto. A drive assembly is disposed within the housing and is configured to move the jaw members upon actuation thereof between an open position and a closed position for clamping tissue with a closure pressure within the range of about 3 kg/cm2 to about 16 kg/cm2. An anti-backdrive assembly is operably disposed within the housing and includes a drive wedge. A solenoid controller is operably coupled to the drive wedge and is configured to selectively move the drive wedge into the drive assembly upon activation thereof to increase the closure pressure between the jaw members in response to tissue expansion during sealing.

Abstract: A vessel sealing instrument includes a housing having a shaft extending from a distal end thereof including an end effector assembly having opposing first and second jaw members operably coupled thereto. One of the jaw members moveable between open and closed positions for clamping tissue with a closure pressure within the range of about 3 kg/cm2 to about 16 kg/cm2. The jaw members are adapted to connect to a generator for providing energy thereto in accordance with a sealing algorithm. An anti-backdrive mechanism is associated with the end effector assembly and includes: a drive shaft coupled to a controller and a screw on opposite ends, the screw configured to engage one of the jaw members upon extension thereof to provide additional closure pressure therebetween. The drive shaft is rotatable by the controller to extend the screw in response to tissue expansion during sealing based on the sealing algorithm.

Abstract: A vessel sealing instrument includes a housing having a shaft extending from a distal end thereof, the distal end including an end effector assembly having a pair of opposing jaw members operably coupled thereto. One or both of the jaw members is moveable between open and closed positions for clamping tissue with a closure pressure. One or both of the jaw members connects to a generator that provides energy thereto in accordance with a sealing algorithm upon activation thereof. An anti-backdrive mechanism is coupled to the end effector assembly and includes a drive shaft coupled at one end to a solenoid and another end that engages one of the jaw members upon extension thereof to provide additional closure pressure between the jaw members. The drive shaft is extendible by the solenoid to extend the drive shaft in response to tissue expansion during sealing based on the sealing algorithm.

Abstract: In one aspect, the present disclosure encompasses polymerization systems for the copolymerization of CO2 and epoxides comprising 1) a catalyst including a metal coordination compound having a permanent ligand set and at least one ligand that is a polymerization initiator, and 2) a chain transfer agent having two or more sites that can initiate polymerization. In a second aspect, the present disclosure encompasses methods for the synthesis of polycarbonate polyols using the inventive polymerization systems. In a third aspect, the present disclosure encompasses polycarbonate polyol compositions characterized in that the polymer chains have a high percentage of —OH end groups and a high percentage of carbonate linkages. The compositions are further characterized in that they contain polymer chains having an embedded polyfunctional moiety linked to a plurality of individual polycarbonate chains.

Abstract: A surgical system includes at least one audio sensor configured to sense audio during a surgical procedure and to output audio data based on the sensed audio. The surgical system further includes a computing device operably coupled to the at least one audio sensor and configured to receive the output audio data from the at least one audio sensor. The computing device includes a processor and memory storing instructions that, when executed by the processor, cause the processor to determine at least one of a cause or a location of a sound based at least on the output audio data and to output an indication of the at least one of the cause or location of the sound.

Abstract: A forceps includes an end effector assembly having first and second jaw members movable between a spaced-apart position and an approximated position for grasping tissue therebetween. A knife assembly having a cutting blade disposed at a distal end thereof is also provided. The knife assembly is translatable relative to the end effector assembly between a retracted position and an extended position, wherein the cutting blade extends between the jaw members to cut tissue grasped therebetween. The knife assembly includes a proximal component and a first distal component that includes the cutting blade. The proximal and first distal components are removably coupled to one another to facilitate replacement of the first distal component. Methods of preparing such forceps for reuse are also provided.

Abstract: An electrosurgical device includes jaw members, a thermal cutting element coupled to one of the jaw members. When the jaw members are in an approximated position, power is delivered to the thermal cutting element to maintain the temperature of the thermal cutting element at an operating temperature for cutting sealed tissue grasped between the jaw members. When the jaw members are in the spaced apart position, power is delivered to the thermal cutting element to maintain the temperature of the thermal cutting element at a standby setpoint temperature. In response to a determination of contact between tissue and the thermal cutting element when the jaw members are in the spaced apart position, power is delivered to the thermal cutting element to increase the temperature of the thermal cutting element from the standby setpoint temperature to a cutting setpoint temperature for dissecting tissue.

Abstract: An electrosurgical system includes jaw members having a cutting element extending therebetween and a generator configured to: provide minimal power to the cutting element to maintain a pre-dissection temperature thereof; sense a change in resistance of the cutting element and ramp up power to a dissection temperature; regulate the temperature of the cutting element by regulating power; and terminate power to the cutting element to allow the cutting element to cool to the pre-dissection temperature before providing power back to the cutting element.

Abstract: A surgical instrument includes a housing having an elongated shaft extending distally therefrom and configured to support an end effector assembly at a distal end thereof. The end effector assembly includes first and second jaw members each having a tissue sealing plate disposed thereon and adapted to connect to an electrosurgical energy source for delivery thereto upon activation thereof. A sensor is disposed on one (or both) of the tissue sealing plates and is configured to communicate data relating to tissue disposed between the first and second jaw members to the electrosurgical energy source for correlation to a resonance frequency of the tissue. The resonance frequency of the tissue, in turn, is used to adjust one or more parameters associated with the delivery of electrosurgical energy to the tissue upon activation thereof.

Abstract: A forceps includes a drive assembly and an end effector assembly having first and second jaw members movable between a spaced-apart position, a first approximated position, and a second approximated position. The drive assembly includes a drive housing and a drive bar. The proximal end of the drive bar is coupled to the drive housing, while the distal end of the drive bar is coupled to at least one of the jaw members. The drive housing and the drive bar are selectively movable in conjunction with one another between a first position and a second position to move the jaw members between the spaced-apart position and the first approximated position. The drive assembly is selectively activatable to move the drive bar independent of the drive housing from the second position to a third position to move the jaw members from the first approximated position to the second approximated position.

Abstract: A forceps includes an end effector assembly having a stop and a plurality of overmold teeth within at least one jaw member. One (or both) of the jaw members is moveable relative to the other between a spaced-apart position and an approximated position for grasping tissue therebetween. One (or both) of the jaw members includes a stop molded within an insulative housing, and an insulator plate with the overmold teeth formed from plastic. The overmold teeth extend through openings within a sealing plate and protrude past the tissue sealing surface of the sealing plate. The stop primarily controls the gap distance between opposing jaw members by bearing most of an applied load and the overmold teeth assist in controlling the gap distance by bearing the remaining applied load.

Abstract: An example method of managing a plurality of hardware accelerators in a computing system includes executing workload management software in the computing system configured to allocate a plurality of jobs in a job queue among a pool of resources in the computer system; monitoring the job queue to determine required hardware functionalities for the plurality of jobs; provisioning at least one hardware accelerator of the plurality of hardware accelerators to provide the required hardware functionalities; configuring a programmable device of each provisioned hardware accelerator to implement at least one of the required hardware functionalities; and notifying the workload management software that each provisioned hardware accelerator is an available resource in the pool of resources.

Abstract: A forceps is provided and includes a housing having a shaft. An end effector assembly operatively connects to a distal end of the shaft and includes a pair of first and second jaw members. One or both of the first and second jaw members is movable relative to the other jaw member from a clamping position to an open position. A resilient member operably couples to at least one of the first and second jaw members. The resilient member is configured to bias the first and second jaw members in the clamping position and provide a closure force on tissue disposed therebetween.

Abstract: A jaw member of an electrosurgical instrument includes an insulative spacer including a face and defining first and second elongated recesses on either side of the face, first and second cleats disposed at least partially within the first and second elongated recesses, respectively, a structural frame, and a tissue treating plate. The structural frame is configured to receive at least a portion of the insulative spacer therein such that first and second elongated sides of the structural frame at least partially overlap the first and second cleats, respectively. The first and second elongated sides are engaged with the first and second cleats, respectively, to thereby secure the insulative spacer relative to the structural frame with the face exposed. The tissue treating plate is disposed on the face of the insulative spacer and is adapted to connect to a source of energy to treat tissue therewith.

Abstract: Embodiments of an invention a processor architecture are disclosed. In an embodiment, a processor includes a decoder, an execution unit, a coherent cache, and an interconnect. The decoder is to decode an instruction to zero a cache line. The execution unit is to issue a write command to initiate a cache line sized write of zeros. The coherent cache is to receive the write command, to determine whether there is a hit in the coherent cache and whether a cache coherency protocol state of the hit cache line is a modified state or an exclusive state, to configure a cache line to indicate all zeros, and to issue the write command toward the interconnect. The interconnect is to, responsive to receipt of the write command, issue a snoop to each of a plurality of other coherent caches for which it must be determined if there is a hit.

Abstract: Described herein are compositions and methods for the production and quantification of barcoded or unique molecular identifier (UMI)-labeled substrates. In one aspect, the substrate is a bead comprising a template oligonucleotide that is elongated by successive extension reactions to provide a bead with an oligonucleotide comprising a plurality of barcodes and conserved anchor regions. Methods are also described for quantifying the amount of template oligonucleotide loaded onto the substrate and the products of the extension reaction after each round and after the final extension.

Abstract: A processor is described. The processor includes model specific register space that is visible to software above a BIOS level. The model specific register space is to specify a granularity of a processing entity of a lock-step group. The processor also includes logic circuitry to support dynamic entry/exit of the lock-step group's processing entities to/from lock-step mode including: i) termination of lock-step execution by the processing entities before the program code to be executed in lock-step is fully executed; and, ii) as part of the exit from the lock-step mode, restoration of a state of a shadow processing entity of the processing entities as the state existed before the shadow processing entity entered the lock-step mode and began lock-step execution of the program code.

Abstract: An energy generator includes a connector port configured to couple to an electrosurgical instrument including an electrode having a polymeric dielectric coating; a power converter configured to generate energy; and a sensor coupled to the power converter and configured to sense a parameter of the energy. The energy generator also includes a controller coupled to the sensor and the power converter. The controller is configured to: control the power converter to output energy to modify an electrical property of the polymeric dielectric coating; and determine whether the electrical property of the polymeric dielectric coating has been sufficiently modified by the energy.

Abstract: A hardfacing metal composition and method of restoring worn work string tubing by application of a hardfacing metal to the worn regions of the work string tubing.

Abstract: A rotating drum screen method for separating solids from thin stillage obtained from ethanol fermentation, the thin stillage comprising one or more of solids and suspended solids. Thin stillage is chemically treated with an anionic polymer to form stable particles of one or more of solids and suspended solids. Introducing the treated thin stillage into a rotating drum screen system. The drum screen includes a filter screen that retains at least a portion of the solids within a hollow portion of the drum screen and which produces a liquid effluent that is discharged from an outer surface of the drum screen. The retained solids are removable from the drum screen via a solid discharge end. A head box is disposed within the hollow portion of the drum screen and has a plurality of fluid flow channel dividers dividing and directing an influent stream outwardly against the drum screen.