Abstract: An antenna component may include a first circuit comprising a first selector coupled in series to a first memory cell, a second circuit comprising a second selector coupled in series to a second memory cell, a first antenna element coupled to the first circuit, a second antenna element coupled to the second circuit, and control circuitry coupled to the first circuit and the second circuit, wherein the control circuitry is configured to use the first circuit to select the first antenna element and use the second circuit to select the second antenna element.

Abstract: A device may include a fluid region. A device may also include a magnetochemical sensor for detecting magnetic particles in the fluid region, wherein the magnetochemical sensor comprises: a first ferromagnetic layer, a second ferromagnetic layer, and a spacer layer situated between and coupled to the first ferromagnetic layer and the second ferromagnetic layer. A device may further include a current-carrying structure for drawing the magnetic particles in the fluid region toward the magnetochemical sensor, wherein: the current-carrying structure consists of a single, undivided structure, and the current-carrying structure is configured to carry a current in at least one direction that is substantially parallel to an in-plane axis or a longitudinal axis of the magnetochemical sensor. The magnetochemical sensor may be one of a plurality of magnetochemical sensors in a sensor array.

Abstract: A microelectronic circuit package may include one or more operative channels, each of the one or more operative channels containing a reactive material, and a seal covering at least a portion of the one or more operative channels. At least one of the one or more operative channels has a maximum width of less than about 100 microns. The seal is non-reactive with the reactive material. Also disclosed are methods of manufacturing a microelectronic circuit package comprising at least one operative channel containing a reactive material.

Abstract: Embodiments described herein generally relate to new apparatus and processes for magnetically detecting an analyte. In an embodiment is provided an apparatus for magnetically detecting the presence of a target analyte in a sample. The apparatus includes: a plurality of magnetic nanoparticles; and a plurality of magnetic sensors disposed within a fluidic channel, each magnetic sensor of the plurality of magnetic sensors coupled, by a binding link, to at least one magnetic nanoparticle of the plurality of magnetic nanoparticles, the binding link adapted to be disrupted in the presence of a target analyte that breaks a covalent bond of the binding link to release the at least one magnetic nanoparticle from the magnetic sensor and indicate the presence of the target analyte.

Abstract: A memory structure is located on a substrate. The memory structure includes electrically conductive lines connected to memory cells with electrically insulating material between the electrically conductive lines. The memory structure further includes an energy-release material in at least one of the electrically conductive lines, the memory cells, the electrically insulating material or the substrate.

Abstract: Disclosed are termination line termination circuits and methods of terminating transmission lines. A transmission line termination circuit for terminating a transmission line may include a termination impedance and a threshold switching device. The threshold switching device may include a first terminal coupled to a first conductor of the transmission line, a second terminal coupled to a second conductor of the transmission line, and an active layer situated between the first terminal and the second terminal. The active layer comprises a switching material configured to be in a substantially conductive state in response to a voltage on the transmission line being in a range above a threshold voltage and in a substantially non-conductive state in response to the voltage on the transmission line being in a range below the threshold voltage.

Abstract: An electronic device includes an enclosure that is formed using a first material and a second material. The first material has a first physical property and the second material has a second physical property that is different from the first physical property. When the first material and the second material are combined, the difference between the physical properties of each material causes a unique pattern to be formed on and/or in the enclosure. The unique pattern is usable to verify the authenticity of the electronic device.

Abstract: A method of performing nucleic acid sequencing may comprise using a disintegrator situated in a fluidic channel of a sequencing device to cleave off a portion of a nucleic acid molecule in the fluidic channel; applying an electrostatic force to divert the portion of the nucleic acid molecule through a nanopore; detecting an ionic current through the nanopore; and determining an identity of at least one nucleotide of the portion of the nucleic acid molecule based at least in part on the ionic current. A system for sequencing nucleic acids may comprise an array comprising a plurality of sequencing devices, each comprising a fluidic channel, a disintegrator embedded in the fluidic channel, and a nanopore coupled to an exit end of the fluidic channel; and detection circuitry coupled to the array and configured to detect ionic currents through the nanopores.

Abstract: Disclosed herein are devices, systems, and methods for controlling the movement of at least one molecule in a first fluid having a first viscosity. The system includes a fluid region defined by at least one fluid-retaining surface, a field-responsive fluid situated in the fluid region, and a field generator for generating a magnetic or electric field across the fluid region. The fluid region is traversable by the at least one molecule. In response to a magnitude of the magnetic or electric field across the fluid region exceeding a threshold magnitude, a viscosity of the field-responsive fluid is greater than the first viscosity.

Abstract: A system for controlling a translocation speed of a molecule through a nanopore may include a fluid chamber containing a solution with a magnetic susceptibility that is different from the magnetic susceptibility of the molecule, a nanopore situated in the fluid chamber, and at least one magnetic component configured to create a magnetic field gradient within the solution to control the translocation speed of a molecule through the nanopore. A system for controlling a translocation speed of a molecule through a nanopore may include a nanopore at least one magnetic component situated to create a magnetic field that causes the molecule to experience a rotational torque as it passes through the nanopore.

Abstract: Disclosed herein are devices, systems, and methods for sequencing nucleic acids using a nanopore. A nucleic acid molecule is fragmented into smaller portions (e.g., individual nucleotides), which are then routed through a nanopore for detection. A device for single-nucleotide sequencing may include a fluidic channel, a disintegrator configured to cleave off portions of a nucleic acid in the fluidic channel, a nanopore coupled to the fluidic channel, and first and second electrodes situated to apply an electrostatic force on the portions of the nucleic acid to divert them out of the fluidic channel and through the nanopore.

Abstract: A method of performing nucleic acid sequencing may comprise using a disintegrator situated in a fluidic channel of a sequencing device to cleave off a portion of a nucleic acid molecule in the fluidic channel; applying an electrostatic force to divert the portion of the nucleic acid molecule through a nanopore; detecting an ionic current through the nanopore; and determining an identity of at least one nucleotide of the portion of the nucleic acid molecule based at least in part on the ionic current. A system for sequencing nucleic acids may comprise an array comprising a plurality of sequencing devices, each comprising a fluidic channel, a disintegrator embedded in the fluidic channel, and a nanopore coupled to an exit end of the fluidic channel; and detection circuitry coupled to the array and configured to detect ionic currents through the nanopores.

Abstract: Disclosed herein are devices, systems, and methods can improve the signal-to-noise ratio of measurements made in biological applications. In some embodiments, an amplifier circuit that comprises a three-terminal device is situated in a configuration (e.g., a common-base or similar configuration) that allows the circuit to detect current through a nanopore while providing feedback to the sense electrode to reduce parasitic capacitance between the sense electrode and the counter electrode. The amplifier circuit may include, for example, a bi-polar junction transistor (BJT), a diamond transistor, a CMOS transistor, an operational transconductance amplifier, a voltage-controlled current source, a transconductor, a macro transistor, and/or a second-generation current conveyor (CCII+).

Abstract: A method of sensing molecules using a detection device, the detection device comprising a plurality of magnetoresistive (MR) sensors and at least one fluidic channel, comprising adding a plurality of molecules to be detected to the at least one fluidic channel, wherein at least some of the plurality of molecules to be detected are coupled to respective magnetic nanoparticles (MNPs), detecting a characteristic of a magnetic noise of a first MR sensor of the plurality of MR sensors, wherein the characteristic of the magnetic noise is influenced by a presence of one or more MNPs in a vicinity of the first MR sensor, and determining, based on the detected characteristic, whether the first MR sensor detected the presence of one or more MNPs in the vicinity of the first MR sensor.

Abstract: A device includes arrays of Non-Volatile Memory (NVM) cells. Reference sequences representing portions of a genome are stored in respective groups of NVM cells. Exact matching phase substring sequences representing portions of at least one sample read are loaded into groups of NVM cells. One or more groups of NVM cells are identified where the stored reference sequence matches the loaded exact matching phase substring sequence using the arrays at Content Addressable Memories (CAMs). Approximate matching phase substring sequences are loaded into groups of NVM cells. One or more groups of NVM cells are identified where the stored reference sequence approximately matches the loaded approximate matching phase substring sequence using the arrays as Ternary CAMs (TCAMs). At least one of the reference sequence and the approximate matching phase substring sequence for each group of NVM cells includes at least one wildcard value when the arrays are used as TCAMs.

Abstract: A method is provided that includes reading a plurality of resistance-switching memory cells comprising a block of data, decoding the block of data using an error correction code decoder, and based on results of the decoding, selectively performing an overwrite-read process to read the block of data. The overwrite read process determines a change in resistance of the resistance-switching memory cells in response to a write pulse.

Abstract: A system for controlling a translocation speed of a molecule through a nanopore may include a fluid chamber containing a solution with a magnetic susceptibility that is different from the magnetic susceptibility of the molecule, a nanopore situated in the fluid chamber, and at least one magnetic component configured to create a magnetic field gradient within the solution to control the translocation speed of a molecule through the nanopore. A system for controlling a translocation speed of a molecule through a nanopore may include a nanopore at least one magnetic component situated to create a magnetic field that causes the molecule to experience a rotational torque as it passes through the nanopore.

Abstract: Disclosed herein are detection methods that use magnetic nanoparticles (MNPs) to allow molecules to be identified. Embodiments of this disclosure include methods of using magnetic sensors (e.g., magnetoresistive sensors) to detect temperature-dependent magnetic fields (or changes in magnetic fields) emitted by MNPs, and, specifically to distinguish between the presence and absence of magnetic fields emitted, or not emitted, by MNPs at different temperatures selected to take advantage of knowledge of how the MNPs' magnetic properties change with temperature. Embodiments disclosed herein may be used for nucleic acid sequencing, such as deoxyribonucleic acid (DNA) sequencing.

Abstract: Disclosed herein are molecular storage systems and methods of reading molecules that include integrity markers. A molecular storage system may comprise read hardware configured to read molecules storing data, and at least one processor coupled to the read hardware. The processor is configured to determine whether a molecule being read by the read hardware includes an expected integrity marker, and, in response to a determination that the molecule being read by the read hardware does not include the expected integrity marker, instruct the read hardware to abandon a read operation associated with the molecule being read by the read hardware. The partial readback can be placed in a buffer and used in an assembly process only if an intact molecule is not available.

Abstract: Disclosed herein are devices, systems, and methods that can improve the SNR of nanopore measurements by mitigating the effect of parasitic capacitance between the sense electrode and the counter electrode. In some embodiments, a feedback circuit is used to inject a charge into the sense electrode to at least partially cancel the parasitic capacitance between the sense electrode and the counter electrode. In some embodiments, bootstrapping of a signal from the amplifier output or from the sense electrode is used to inject a charge on the counter electrode to substantially cancel the parasitic capacitance.