Abstract: A system and method to verify that the driver or operator of a vehicle or piece of equipment has completed a 360-degree walk-around inspection of the vehicle/equipment. The vehicle/equipment will be equipped with an electronic beacon that detects the direction of the driver/operator via a mobile electronic device that the driver/operator carries. As the operator walks around the vehicle/equipment, the electronic beacon installed on the vehicle/equipment recognizes the location of the mobile electronic device as the driver/operator walks around the vehicle/equipment performing their inspection. In certain embodiments, the electronic beacon and mobile electronic device determine the operator's inspection are Angle of Arrival and Angle of Departure relative to each electronic beacon. The determination may require different combinations of transmitters and receivers.

Abstract: A vehicle damage detection system comprising: a booth having a booth entrance for a vehicle to enter the booth and a booth exit for the vehicle to exit the booth; a plurality of damage assessment cameras orientated to capture damage assessment images of the vehicle when the vehicle is located at a damage assessment zone within the booth; a data processor configured to: receive the damage assessment images; execute a program to identify and assess damage to the vehicle using the damage assessment images; and generate a damage report quantifying the damage to the vehicle.

Abstract: A computing device is described that receives an electronic message encoded with first rendering instructions and second rendering instructions. The first rendering instructions are accelerated mobile pages instructions and the second rendering instructions are at least one of plain text or hypertext markup language instructions. The computing device generates a rendering of the electronic message by at least: rendering the second rendering instructions, while refraining from rendering the first rendering instructions, in response to determining that the first rendering instructions are not valid accelerated mobile pages instructions. The computing device outputs, using a display, the rendering of the electronic message.

Abstract: The invention relates to a method of determining the presence or absence of a target analyte in a sample. The method comprises immobilising any target analyte present in the sample on a surface; contacting the surface with: (i) a first detection agent that binds specifically to the target analyte; and (ii) a reporter polynucleotide, wherein the reporter polynucleotide is bound to, or binds to, the first detection agent; and contacting a transmembrane pore with any reporter polynucleotide that has been immobilised on the surface, wherein the reporter polynucleotide is immobilised on the surface by binding of the first agent to the target analyte, and using the transmembrane pore to detect the reporter polynucleotide, thereby determining the presence or absence of the target analyte in the sample.

Abstract: The present disclosure provides prochelators as targeted prodrugs for cancer, such as prostate cancer, and methods of making and using the same.

Abstract: A computing device is described that receives, at a first particular time, first notification data. Responsive to receiving the first notification data, the computing device outputs, at a first intensity level, a first alert associated with the first notification data. The computing device receives, at a second particular time after the first particular time, second notification data. Responsive to the computing device receiving an indication of user interaction with the computing device between the first particular time and the second particular time, the computing device outputs, at the first intensity level, a second alert associated with the second notification data. Conversely, responsive to the computing device not receiving the indication of user interaction with the computing device, the computing device either outputs, at a second intensity level that is less than the first intensity level, the second alert, or refrains from outputting the second alert entirely.

Abstract: The present disclosure provides biomarkers for the identification of prostate cancer and methods of use. The present disclosure also provide biomarkers that can be used for determining risk of developing prostate cancer, aggressiveness of prostate cancer and survival rate for subpopulations of African American males or non-Hispanic white males.

Abstract: Example devices and methods for compensating for monitoring a surge protection device are provided. In some embodiments, a device is configured to couple to a surge protection device. The device comprises a processor that is capable of sending a DC current signal. A serial data interface is electrically connected to the processor and includes at least one shift register. The device also comprises a multiplexer coupled to the serial data interface. The serial data interface is operable to direct the DC current through the multiplexer. The device also comprises an analog to digital converter (optionally embedded within the processor) that is operable to output a digital signal corresponding to a voltage induced by the DC current signal. Returned DC signals represent surge protection device's health and a multitude of other surge module information.

Abstract: The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR expression and methods of using these splice-switching oligonucleotides to treat cancer, specifically castrate resistant prostate cancer.

Abstract: A mobile gateway device that includes a receiver configured to electronically receiving wirelessly-transmitted data from a beacon connected to a vehicle or piece of equipment being tracked or monitored, where the wirelessly-transmitted data relates to a status or location of the vehicle or piece of equipment. A transmitter is configured to wirelessly transmit the data received from the beacon to a smart device or to a cloud-based computer server. The mobile gateway device includes a processor and electronic memory. The processor is configured to control operation of the receiver and the transmitter. The electronic memory is configured to store the wirelessly-transmitted data. A housing houses the receiver, transmitter, processor and electronic memory.

Abstract: The invention relates to a new method of determining in a sample the presence or absence of one or more analyte members of a group of two or more analytes. The invention therefore relates to a multiplex assay for determining the presence or absence of each analyte in a group of multiple analytes. The assay uses aptamers and transmembrane pores.

Abstract: Automatic house vent is a house vent system that automatically closes all house vents when electrical power is shut off to the house. Automatic house vent is a fire prevention mechanism that closes all house vents in order to prevent burning ambers from entering the house through a house vent and starting a fire from the inside of the house. It is standard procedure during forest fires for the authorities to shut off electrical power to communities in the path of the fire. Each house vent is mechanically opened and closed by an electric solenoid actuator that is connected by electrical wiring to a special circuit breaker located in the house electrical panel or breaker box.

Abstract: A screen assembly, such as a downhole/sand screen assembly, comprising first and second screen portions or screens longitudinally coupled together, wherein there is provided a fluid flow path between the first and second screen portions or screen. Optionally, the first and second sleeves are coupled or connected by a centralizer or further sleeve or screen, and/or optionally by or via first and second support ring.

Abstract: A screen assembly, such as a downhole/sand screen assembly, comprising first and second screen portions or screens longitudinally coupled together, wherein there is provided a fluid flow path between the first and second screen portions or screen. Optionally, the first and second sleeves are coupled or connected by a centralizer or further sleeve or screen, and/or optionally by or via first and second support ring.

Abstract: Example devices and methods for compensating for monitoring a surge protection device are provided. In some embodiments, a device is configured to couple to a surge protection device. The device comprises a processor that is capable of sending a DC current signal. A serial data interface is electrically connected to the processor and includes at least one shift register. The device also comprises a multiplexer coupled to the serial data interface. The serial data interface is operable to direct the DC current through the multiplexer. The device also comprises an analog to digital converter (optionally embedded within the processor) that is operable to output a digital signal corresponding to a voltage induced by the DC current signal. Returned DC signals represent surge protection device's health and a multitude of other surge module information.

Abstract: A system to optically measure an ear includes a controller with logic that when executed by the controller causes the system to perform operations. Operations may include capturing the one or more images of the ear using the one or more image sensors, and generating image data from the one or more images. 3D keypoints of the ear are calculated from the image data, and a 3D model of the ear is generated using the 3D keypoints.

Abstract: Apparatus and methods for manufacturing compostable, biodegradable drink straws from polyhydroxyalkanoate (PHA) material are disclosed herein. Such apparatus may include a hopper that contains raw PHA material, an extruder that receives the raw PHA material from the hopper and produces extruded PHA material, one or more waters baths that cool the extruded PHA material, a puller that pulls a tubular stream of PHA material through the system, and a cutter that is configured to cut the stream of PHA material into finished straws. The finished straws may be soil- and marine-biodegradable, as well as home- and industrial-compostable.