Patents by Inventor Darin J. Messina

Darin J. Messina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
    Patent number: 11844878
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: December 19, 2023
    Assignee: Allergan, Inc.
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • CROSSLINKED HA-COLLAGEN HYDROGELS AS DERMAL FILLERS
    Publication number: 20230040919
    Abstract: The present disclosure relates to a crosslinked macromolecular matrix comprising lysine; hyaluronic acid; and collagen; wherein the hyaluronic acid is crosslinked to the collagen by at least one endogenous amine group on the collagen and/or by at least one amine group present on the lysine.
    Type: Application
    Filed: December 28, 2019
    Publication date: February 9, 2023
    Inventors: Christopher A. TRAINA, Artem B. KUTIKOV, Xiaojie YU, Christopher K. HEE, Darin J. MESSINA, Julie MORELL, Florent DURIEUX, Olivier GUETTA, Jean-Xavier ROCA MARTINEZ
  • PHYSICAL MIX HA-COLLAGEN DERMAL FILLERS
    Publication number: 20230042665
    Abstract: The disclosure relates to compositions comprising crosslinked hyaluronic acid physically mixed with collagen. Also contemplated are methods of improving an aesthetic quality of an anatomic feature of a human being.
    Type: Application
    Filed: December 28, 2020
    Publication date: February 9, 2023
    Inventors: Iossif STREHIN, Xiaojie YU, Darin J. MESSINA, Julie MORELL, Florent DURIEUX, Jean-Xavier ROCA MARTINEZ
  • Cartilage and bone repair and regeneration using postpartum-derived cells
    Patent number: 11191789
    Abstract: Cells derived from postpartum tissue and methods for their isolation and induction to differentiate to cells of a chondrogenic or osteogenic phenotype are provided by the invention. The invention further provides cultures and compositions of the postpartum-derived cells and products related thereto. The postpartum-derived cells of the invention and products related thereto have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications, for example, in the treatment of bone and cartilage conditions.
    Type: Grant
    Filed: June 25, 2004
    Date of Patent: December 7, 2021
    Assignee: Depuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Agnieszka Seyda, Sridevi Dhanaraj, Ziwei Wang, Alexander M. Harmon, Ian Ross Harris, Darin J. Messina, Sanjay Mistry, Anna Gosiewska, Chin-Feng Yi
  • Postpartum cells derived from placental tissue, and methods of making and using the same
    Patent number: 11000554
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: May 11, 2021
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian R. Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • CO-CROSSLINKED HYALURONIC ACID-SILK FIBROIN HYDROGELS FOR IMPROVING TISSUE GRAFT VIABILITY AND FOR SOFT TISSUE AUGMENTATION
    Publication number: 20200376159
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Application
    Filed: August 14, 2020
    Publication date: December 3, 2020
    Inventors: Xiaojie YU, Darin J. MESSINA, Elizabeta PAVLOVIC, Cunqi CUI, Kate M. SMITHER
  • Repair and regeneration of ocular tissue using postpartum-derived cells
    Patent number: 10744164
    Abstract: Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of ocular tissue using the postpartum-derived cells are also disclosed.
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: August 18, 2020
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Sanjay Mistry, Darin J. Messina
  • Co-crosslinked hyaluronic acid-silk fibroin hydrogels for improving tissue graft viability and for soft tissue augmentation
    Patent number: 10744227
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: August 18, 2020
    Assignee: ALLERGAN, INC.
    Inventors: Xiaojie Yu, Darin J. Messina, Elizabeta Pavlovic, Cunqi Cui, Kate M. Smither
  • CROSSLINKED HYALURONIC ACID-COLLAGEN GELS FOR IMPROVING TISSUE GRAFT VIABILITY AND SOFT TISSUE AUGMENTATION
    Publication number: 20200000968
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Application
    Filed: July 31, 2019
    Publication date: January 2, 2020
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • Postpartum cells derived from umbilical cord tissue, and methods of making and using the same
    Patent number: 10500234
    Abstract: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: December 10, 2019
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Sanjay Mistry, Anthony J. Kihm, Ian R. Harris, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • CO-CROSSLINKED HYALURONIC ACID-SILK FIBROIN HYDROGELS FOR IMPROVING TISSUE GRAFT VIABILITY AND FOR SOFT TISSUE AUGMENTATION
    Publication number: 20190255215
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Application
    Filed: May 1, 2019
    Publication date: August 22, 2019
    Inventors: Xiaojie YU, Darin J. MESSINA, Elizabeta PAVLOVIC, Cunqi CUI, Kate M. SMITHER
  • Postpartum cells derived from placental tissue, and methods of making and using the same
    Patent number: 10383898
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: August 20, 2019
    Assignee: Depuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian Ross Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • POSTPARTUM CELLS DERIVED FROM PLACENTAL TISSUE, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20190192577
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Application
    Filed: March 4, 2019
    Publication date: June 27, 2019
    Applicant: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian R. Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Co-crosslinked hyaluronic acid-silk fibroin hydrogels for improving tissue graft viability and for soft tissue augmentation
    Patent number: 10300169
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: May 28, 2019
    Assignee: Allergan, Inc.
    Inventors: Xiaojie Yu, Darin J. Messina, Elizabeta Pavlovic, Cunqi Cui, Kate M. Smither
  • Postpartum cells derived from placental tissue, and methods of making and using the same
    Patent number: 10220059
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: March 5, 2019
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventors: Anthony J. Kihm, Ian Ross Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Postpartum cells derived from placental tissue, and methods of making and using the same
    Patent number: 10195233
    Abstract: Cells derived from postpartum placenta and methods for their isolation are provided by the invention. The invention further provides cultures and compositions of the placenta-derived cells. The placenta-derived cells of the invention have a plethora of uses, including but not limited to research, diagnostic, and therapeutic applications.
    Type: Grant
    Filed: February 27, 2017
    Date of Patent: February 5, 2019
    Assignee: DePuy Synthes Products, Inc.
    Inventors: Anthony J. Kihm, Ian Ross Harris, Sanjay Mistry, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • CO-CROSSLINKED HYALURONIC ACID-SILK FIBROIN HYDROGELS FOR IMPROVING TISSUE GRAFT VIABILITY AND FOR SOFT TISSUE AUGMENTATION
    Publication number: 20180055971
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Application
    Filed: August 24, 2017
    Publication date: March 1, 2018
    Inventors: Xiaojie YU, Darin J. MESSINA, Elizabeta PAVLOVIC, Cunqi CUI, Kate M. SMITHER
  • CROSSLINKED HYALURONIC ACID-COLLAGEN GELS FOR IMPROVING TISSUE GRAFT VIABILITY AND SOFT TISSUE AUGMENTATION
    Publication number: 20170348463
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Application
    Filed: August 25, 2017
    Publication date: December 7, 2017
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • POSTPARTUM CELLS DERIVED FROM UMBILICAL CORD TISSUE, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20170326183
    Abstract: Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to their cell surface markers, gene expression, and their secretion of trophic factors are described.
    Type: Application
    Filed: July 27, 2017
    Publication date: November 16, 2017
    Applicant: DePuy Synthes Products, Inc.
    Inventors: Sanjay Mistry, Anthony J. Kihm, Ian R. Harris, Alexander M. Harmon, Darin J. Messina, Agnieszka Seyda, Chin-Feng Yi, Anna Gosiewska
  • Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
    Patent number: 9782517
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: October 10, 2017
    Assignee: Allergan, Inc.
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina