Patents by Inventor Darin J. Messina

Darin J. Messina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6852532
    Abstract: A method for isolating human neuroepithelial precursor cells from human fetal tissue by culturing the human fetal cells in fibroblast growth factor and chick embryo extract and immunodepleting from the cultured human fetal cells any cells expressing A2B5, NG2 and eNCAM is provided. In addition, methods for transplanting these cells into an animal are provided. Animals models transplanted with these human neuroepithelial precursor cells and methods for monitoring survival, proliferation, differentiation and migration of the cells in the animal model via detection of human specific markers are also provided.
    Type: Grant
    Filed: March 21, 2001
    Date of Patent: February 8, 2005
    Assignee: University of Utah Research Foundation
    Inventors: Margot Mayer-Proschel, Mahendra S. Rao, Patrick A. Tresco, Darin J. Messina
  • Publication number: 20020168767
    Abstract: A method for isolating human neuroepithelial precursor cells from human fetal tissue by culturing the human fetal cells in fibroblast growth factor and chick embryo extract and immunodepleting from the cultured human fetal cells any cells expressing A2B5, NG2 and eNCAM is provided. In addition, methods for transplanting these cells into an animal are provided. Animals models transplanted with these human neuroepithelial precursor cells and methods for monitoring survival, proliferation, differentiation and migration of the cells in the animal model via detection of human specific markers are also provided.
    Type: Application
    Filed: March 21, 2001
    Publication date: November 14, 2002
    Inventors: Margot Mayer-Proschel, Mahendra S. Rao, Patrick A. Tresco, Darin J. Messina