Abstract: A method and system for classifying a target nucleic acid includes exposing, in a test system, one or more capture probes to the target nucleic acid. The one or more capture probes is attached to a surface. A first hybridization condition is established in the test system. A first degree of hybridization of the one or more capture probes with the target nucleic acid under the first hybridization condition is determined. A second hybridization condition in the test system is established. A second degree of hybridization of the one or more capture probes with the target nucleic acid under the second hybridization condition is determined and the target nucleic acid is classified by comparing the first and the second degrees of hybridization.

Abstract: Component based dynamic guest instantiation is disclosed. For example, a memory stores a content store, and a virtualization engine executes on one or more processors to receive a request to launch an application that is configured to execute in a guest. A file system of the guest is constructed based on metadata associated with the application. A plurality of components of the application, including a first component defined in the metadata, are loaded to the file system from the content store. The first application is launched in the guest.

Abstract: The present invention provides, in part, compounds of Formula I: and pharmaceutically acceptable salts thereof; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds or salts, and their uses for treating D1-mediated (or D1-associated) disorders including, e.g., schizophrenia (e.g., its cognitive and negative symptoms), cognitive impairment (e.g., cognitive impairment associated with schizophrenia, AD, PD, or pharmacotherapy therapy), and Parkinson's disease.

Abstract: Multicast transmissions are efficient but do not allow for individual acknowledgement that the data was received by each receiver. This is not acceptable for isochronous systems that require specific levels of QoS for each device. A multimedia communications protocol is provided that uses a novel multi-destination burst transmission protocol in multimedia isochronous systems. The transmitter establishes a bi-directional burst mode for multicasting data to multiple devices and receiving Reverse Start of Frame (RSOF) delimiters from each multicast-destination receiver in response to multiple SOF delimiters, thus providing protocol-efficient multi-destination acknowledgements.

Abstract: Techniques for setting a boost target for a turbocharged engine comprise (i) operating the engine in a scavenging mode such that opening of intake and exhaust valves of cylinders of the engine overlap and (ii) while transitioning the engine in/out of the scavenging mode: determining an engine torque request, creating a torque reserve by setting independent targets for throttle inlet pressure (TIP) and intake manifold absolute pressure (MAP), determining a target TIP based on a target total air charge, engine speed, and a previously-determined target engine volumetric efficiency (VE), controlling a wastegate valve based on the target TIP, determining a target MAP based on the engine torque request, and controlling a throttle valve based on the target MAP. During steady-state scavenging operation, the controller calculates a conventional target TIP based on the engine torque request and controls the wastegate valve based on the conventionally calculated target TIP.

Abstract: The invention relates to compositions and methods for utilizing lysophosphatidylcholine scaffolds. The compositions and methods can be used for LPC-mediated delivery of fatty acids and other molecules; to screen and identify fatty acid formulations for parenteral nutrition; and for live animal organ imaging, among other uses. The invention also provides compositions and methods for utilizing mutations and polymorphisms in human Mfsd2a as markers for neurological deficits.

Abstract: A wellhead assembly includes an outer wellhead member having a bore and an inner wellhead member located in the bore, defining an annular pocket between the outer and inner wellhead members. A sealing assembly is located within the annular pocket, the sealing assembly having an annular seal and an energizing ring. The energizing ring engages inner and outer legs of the annular seal to push the inner and outer legs into sealing engagement with the inner and outer wellhead members. A retainer nut is threadingly attached to the free end of the outer leg of the sealing assembly. Mating grooves are located on one of an inner diameter of the retainer nut and an outer diameter of the energizing ring and mating protrusions located on the other. The mating protrusions mate with the mating grooves to prevent relative axial movement between the energizing ring and the annular seal.

Abstract: Systems and methods for a turbocharged gasoline engine utilize a controller configured to receive a set of parameters including a measured pressure delta across an exhaust gas recirculation (EGR) valve disposed in a low pressure EGR (LPEGR) system of the engine and a measured pressure at an outlet of a differential pressure (dP) valve disposed in and distinct from a throttle valve of an induction system of the engine. The controller is further configured to determine a set of modeled pressures based on the set of parameters, a target EGR valve mass flow, a target EGR valve delta pressure, a current dP valve mass flow, and a pressure at an outlet of the air filter, determine target positions for the EGR valve and the dP valve based on the set of modeled pressures, and control the EGR valve and the dP valve based on their respective target positions.

Abstract: An integral multi-dispenser liquid container includes a plurality of hand pump dispensers positioned linearly, triangularly or squarely above a lower container compartment having a centrally-located liquid fill port. A central portion of the lower compartment is removed to cause residual liquid to pool at the suction tubes of the hand-pumps. One or more reinforced grip handles span between the hand-pump dispensers above the lower compartment. The hand-pumps can dispense different liquid volumes as needed in the field and do not need to be removed to refill the container. An internal baffle can be installed within the inside the lower compartment so that different liquids can be carried and dispensed.

Abstract: A tool holder apparatus for a motorized vehicle for residential use includes an attachment member, a rotary table attached to the attachment member, the table having fixed and relatively movable table members, and a tool holder attached to the movable table member. The attachment member removably fastens the tool holder apparatus to a member of the motorized vehicle.

Abstract: Described herein are quinazoline-based compounds and formulations thereof. In some embodiments, the compounds and/or formulations thereof can be effective to inhibit and/or kill A. baumannii. Also described herein are methods of treating a subject in need thereof by administering to the subject in need thereof a quinazoline-based compound and/or formulation thereof to the subject in need thereof.

Abstract: Techniques for setting a boost target for a turbocharged engine comprise (i) operating the engine in a scavenging mode such that opening of intake and exhaust valves of cylinders of the engine overlap and (ii) while transitioning the engine in/out of the scavenging mode: determining an engine torque request, creating a torque reserve by setting independent targets for throttle inlet pressure (TIP) and intake manifold absolute pressure (MAP), determining a target TIP based on a target total air charge, engine speed, and a previously-determined target engine volumetric efficiency (VE), controlling a wastegate valve based on the target TIP, determining a target MAP based on the engine torque request, and controlling a throttle valve based on the target MAP. During steady-state scavenging operation, the controller calculates a conventional target TIP based on the engine torque request and controls the wastegate valve based on the conventionally calculated target TIP.

Abstract: Systems and methods for a turbocharged gasoline engine utilize a controller configured to receive a set of parameters including a measured pressure delta across an exhaust gas recirculation (EGR) valve disposed in a low pressure EGR (LPEGR) system of the engine and a measured pressure at an outlet of a differential pressure (dP) valve disposed in and distinct from a throttle valve of an induction system of the engine. The controller is further configured to determine a set of modeled pressures based on the set of parameters, a target EGR valve mass flow, a target EGR valve delta pressure, a current dP valve mass flow, and a pressure at an outlet of the air filter, determine target positions for the EGR valve and the dP valve based on the set of modeled pressures, and control the EGR valve and the dP valve based on their respective target positions.

Abstract: Disclosed is a securities trading program for trading individual lots of a security which can be run at a security trader's computer station. The program generates a trading screen comprising a listing of multiple bids for the security, each bid having a price, as well as a listing of multiple priced offers for the security. The bid and offer listings are active, enabling the trader to hit any one of the displayed bids or take any one of the displayed offers, for example by selecting and clicking on a displayed bid or offer. In one embodiment, the bids and offers are arranged in side-by-side columns on the trader's screen, helping the trader to rapidly overview the market for a particular security, and compare different, possibly competitive, securities by paging through level-of-interest windows for each security.

Abstract: A wellhead assembly includes an outer wellhead member having a bore and an inner wellhead member located in the bore, defining an annular pocket between the outer and inner wellhead members. A sealing assembly is located within the annular pocket, the sealing assembly having an annular seal and an energizing ring. The energizing ring engages inner and outer legs of the annular seal to push the inner and outer legs into sealing engagement with the inner and outer wellhead members. A retainer nut is threadingly attached to the free end of the outer leg of the sealing assembly. Mating grooves are located on one of an inner diameter of the retainer nut and an outer diameter of the energizing ring and mating protrusions located on the other. The mating protrusions mate with the mating grooves to prevent relative axial movement between the energizing ring and the annular seal.

Abstract: Embodiments disclosed herein relate to an interactive surgical drape and system including at least one sensor and at least one controller that operates indicating sensing feedback from the at least one sensor to cause display of information on a dynamic display integrated with the interactive surgical drape. The dynamic display assists the surgical team while performing surgery and can operate to improve the efficiency and/or effectiveness of the surgical team.