Abstract: This disclosure relates to selective data generation, transmission and processing in customized healthcare services. In some aspects, a method includes determining one or more conditions for collecting a user's health data to assess the user's health status; determining that the one or more conditions are satisfies based on a first set of data from a first set of devices; in response to determining that the one or more conditions are satisfied, activating a second set of devices configured to monitor and collect the user's health data; receiving a second set of data from the second set of devices; assessing the user's health status using a machine learning model based on the first set of data and the second set of data; and generating and outputting for display a report including assessment results of the user's health status.

Abstract: An urban design pipeline automatically generates design options for an urban design project. The urban design pipeline includes a geometry engine and an evaluation engine. The geometry engine analyzes design criteria and design objectives associated with the urban design project and then generates numerous candidate designs that meet the design criteria and optimize the design objectives to varying degrees. The evaluation engine evaluates each candidate design to generate a set of metrics. The geometry engine modifies the candidate designs based on corresponding metrics to generate candidate designs that better meet the design criteria and more effectively achieve the design objectives.

Abstract: The disclosure of a compound of Formula I or a pharmaceutically acceptable salt thereof The variables W, R1, R2, R3, and R4 are defined in the disclosure. The disclosure provides a compound or salt of Formula I together with a pharmaceutically acceptable carrier. The disclosure also provides methods of treating a patient for Parkinson's disease and related syndromes, dyskinesia, especially dyskinesias secondary to treating Parkinson's disease with L-DOPA, neurodegenerative disorders such as Alzheimer's disease and dementia, Huntington's disease, restless legs syndrome, bipolar disorder and depression, schizophrenia, cognitive dysfunction, or substance use disorders, the methods comprising administering a compound of Formula I or salt thereof to the patient. The disclosure provides combination methods of treatment in which the compound of Formula I is administered to the patient together with one or more additional active agents.

Abstract: An SMA actuator assembly (2) comprising: a support structure (10); a movable part (20) that is movable relative to the support structure; and an SMA wire (30) connected at its ends to the movable part and/or the support structure and arranged to move the movable part relative to the support structure, wherein the SMA wire is arranged to be in contact between its ends with one or more contact portions of the movable part and/or support structure, and wherein each contact portion comprises a plurality of contact sections (10a, 20a) that are in direct contact with the SMA wire, wherein the plurality of contact sections are separated by one or more gaps between the contact sections.

Abstract: An urban design pipeline is configured to automatically generate design options that meet competing design objectives. A geometry engine within the urban design pipeline generates candidate designs for an urban design project. An evaluation engine within the urban design pipeline evaluates the degree to which each candidate design addresses the competing design objectives to produce a set of design metrics. A tradeoff engine within the urban design pipeline generates a design tradeoff space based on the candidate designs and corresponding design metrics. The tradeoff engine traverses the design tradeoff space based on performance modifications to adjust the degree to which the competing design objectives are addressed. The performance modifications can be obtained from any number of stakeholders in the urban design project.

Abstract: A design engine is configured to automatically generate designs for multi-family housing projects that simultaneously meet local construction regulations while also meeting specific financial targets. The design engine includes a design analyzer that generates design trends based on a database of historical designs. A feature extractor within the design analyzer performs a geometrical analysis of the historical designs to generate a library of features. A feature parameterizer within the design analyzer performs a parameterization process to generate one or more parametric values for each feature. A parameter correlator within the design analyzer compares different subsets of parametric values to identify relationships between those values. A trend aggregator identifies relationships that occur across multiple historical designs to determine a set of design trends. The design engine generates design options using the design trends.

Abstract: A fish pump loading system includes a pump suction inlet to receive a first input water stream including a combination of fish and water. At least one water flow generator receives a second input water stream that is independent of the first input water stream. A water flow generator nozzle modifies the second input water stream at an outlet of the water flow generator to produce a modified output water stream and is positioned in proximity to the pump suction inlet such that the first input water stream interacts with and alters the modified output water stream to produce a conversion zone having a first fast-moving conversion current drawing into the pump suction inlet to rapidly convert the fish into the first input water stream after the fish swim into the conversion zone. A pump suction outlet transmits the combination of fish and water to a fish pump entrance.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for asynchronous deep reinforcement learning. One of the systems includes a plurality of workers, wherein each worker is configured to operate independently of each other worker, and wherein each worker is associated with a respective actor that interacts with a respective replica of the environment during the training of the deep neural network.

Abstract: Systems, methods and computer-readable storage media can be used to debug content items. One example method includes presenting, by a mobile application executing on a mobile device, a first application interface. The example method further includes detecting, by the mobile device, a predetermined user action. The example method further includes, in response to detecting the predetermined user action, generating debugging information from content event logs, wherein the content event logs are associated with content item slots in which content items are presented in the mobile application and presenting, by a debugging interface, the debugging information.

Abstract: Antenna-plexers for interference cancellation are provided herein. In certain embodiments, a wireless device includes an antenna, an antenna-plexer coupled to the antenna and configured to generate a feedback signal, a transmitter configured to transmit a transmit signal to the antenna by way of the antenna-plexer, a receiver configured to process a receive signal, and a feedback receiver configured to process the feedback signal from the antenna-plexer to provide compensation to the receive signal.

Abstract: A safety signaling system comprises a panel including an HMI for setting first operator safety condition to one of VOTE and NO VOTE, a first optical transceiver for connection to a first optical fiber and a second optical transceiver for connection to a second optical fiber. Panel control circuitry connected between HMI and first transceiver activates first transceiver to transmit continuous wave (CW) light signal into first optical fiber only while HMI sets first operator safety condition to VOTE. A remote interface includes a third optical transceiver for connection to first optical fiber, a fourth optical transceiver for connection to second optical fiber, and remote interface control circuitry connected to third transceiver.

Abstract: A method and apparatus for performing quantum error correction using an automorphism code related to the honeycomb code. The automorphism code is based on Kramers-Wannier (KW) duality. For embodiments on a hexagonal lattice using three repeated time steps, ? of the pixels are active in a given time steps. In a given time step r, a KW circuit is applied to plaquettes labeled r mod 3, transferring quantum information from the active qubits at the beginning to a new set of active qubits at the end of the time step. Each of the three plaquette types is associated with one stabilizer either given by a product of six Z operators or three X operators. The KW circuit maps the product of X operators to the product of Z operators and vice-versa. The stabilizer group of the superlattice toric code changes every round.

Abstract: RF communication systems with interference cancellation for coexistence are provided herein. In certain embodiments, a method of interference cancellation includes filtering a radio frequency (RF) transmit signal to generate a first RF feedback signal using a first filter of a front end system, filtering the RF transmit signal to generate a second RF feedback signal using a second filter of the front end system, processing the first RF feedback signal to generate a first digital interference cancellation signal using a first feedback receiver, processing the second RF feedback signal to generate a second digital interference cancellation signal using a second feedback receiver, and compensating an RF receive signal for interference based on the first digital interference cancellation signal and the second digital interference cancellation signal using a receiver.

Abstract: An urban design pipeline automatically generates design options for an urban design project. The urban design pipeline includes a geometry engine and an evaluation engine. The geometry engine analyzes design criteria, design objectives, and design heuristics associated with the urban design project and then generates numerous candidate designs. The design criteria specify a property boundary associated with a region of land to be developed. The design objectives indicate a specific type of topology that is derived from an existing urban layout. The design heuristics include different sets of construction rules for generating designs with specific types of topologies. The geometry engine generates candidate designs that conform to the property boundary and have topological characteristics in common with the existing urban layout.

Abstract: Aspects of the present disclosure involve utilizing network threat information to manage one or more security devices or policies of a communication network. The security system may receive threat intelligence data or information associated with potential threats to a communications network and process the threat intelligence data to determine one or more configurations to apply to security devices of a network. The system may then generate a rule or action to respond to the identified attack, such as a firewall rule for a firewall device to block traffic from the source of the attack. The threat intelligence information may include a confidence score indicating a calculated confidence in the identification of the malicious communications, which may be utilized by the system to determine the type of action taken on the security devices of the network in response to the information or data.

Abstract: Compounds of Formula I, Formula II, and Formula III and the pharmaceutically acceptable salts thereof are disclosed. The variables R1-10 are disclosed herein. The compounds are useful for treating central nervous system disorders, especially those involving substance use disorder and/or withdrawal syndrome. Pharmaceutical compositions containing compounds of Formula I or Formula II or Formula III and methods of treatment comprising administering compounds of Formula I or Formula II or Formula III are also disclosed.

Abstract: An urban design pipeline automatically generates design options for an urban design project. The urban design pipeline includes a geometry engine and an evaluation engine. The geometry engine analyzes design criteria, design objectives, and design heuristics associated with the urban design project and then generates numerous candidate designs. The design criteria specify a property boundary associated with a region of land to be developed. The design objectives indicate a specific type of topology that is derived from an existing urban layout. The design heuristics include different sets of construction rules for generating designs with specific types of topologies. The geometry engine generates candidate designs that conform to the property boundary and have topological characteristics in common with the existing urban layout.

Abstract: The present invention provides alternate means in form of a medicinal composition comprising botanical extracts comprised of an organic liquid extract derived from Laminaria japonica and an organic liquid extract derived from Andrographis paniculate along with other components as disclosed herein for the prevention of viral binding, uptake, replication, infection, and disease caused by viral pathogens. Combined the aforementioned organic botanical extracts produce strong additivity and synergistic effect against the viral pathogens contributing towards significant reduction in viral binding, uptake, replication, infection, and disease. Also disclosed are the methods to formulate the aforementioned medicinal composition and dosage forms for use in a method for prophylactic treatment and prevention of viral binding, uptake, replication, infection, and disease caused by viral pathogens in an individual, which is also disclosed herein.

Abstract: The present disclosure provides compositions of effector proteins. The compositions may comprise engineered guide nucleic acids. Also disclosed are the methods and systems for detecting and modifying target nucleic acids using the same. The compositions may provide nucleic acid modification and/or detection at relatively high temperatures.

Abstract: Participants as requestors using a requesting network element request one or more tokenization processors to generate tokens that represent a sanitized version of data such that the resultant tokens are amenable to comparison across participants. As circumstances warrant, one or more such tokens can be submitted to the tokenization processor(s) to privately retrieve the original data. Role-based access control scope parameters and tokenization processor-specific tokenization processor secrets can be embedded into reversible tokens that remain invariant under updating of the tokenization processor secrets across tokenization processors.