Abstract: Methods for analysis of silicon chips and other electrical components are presently slow, often requiring much human intervention. An electronic component authentication system is provided comprising apparatus to obtain images, of an electronic component to be authenticated, in the visible spectrum, and the infrared spectrum, the system further comprising apparatus to obtain X-ray images of the electronic component and to process at least some of those X-ray images to provide a 3D tomosynthesis image of the electronic component, the system further comprising a processor configured to analyse the obtained images to ascertain criteria relating to the electronic component and authenticate the ascertained criteria against a set of known criteria.

Abstract: Examples are disclosed herein that relate to vehicles, composite parts, and methods for forming a composite part for a vehicle. In one example, a vehicle comprises a composite part comprising a skin comprising one or more material layers. The composite part further comprises a stiffener comprising one or more material layers, wherein the stiffener comprises a flange and a web. The composite part also includes an additively manufactured sub-structure positioned between at least a portion of the skin and at least a portion of the stiffener. The additively manufactured sub-structure comprises at least one flange portion, at least one radius, and at least one radius filler. A polymer matrix is co-infused within the skin, the stiffener, and the additively manufactured sub-structure.

Abstract: Some embodiments relate to an electro-mechanical actuator that includes a screw, structurally segregated (split) housings, first and second nuts coupled to the screw, a sensor assembly, a plurality of motors, and a controller. The first nut is coupled to a first mounting point, and the second nut is coupled to a second mounting point. The sensor assembly may generate signals indicative of (e.g., relative) positions of left and right units of the actuator or positions of the first nut and the second nut on the screw. The controller controls the motors based on the signals generated by the sensor assembly. The motors may rotate each nut about a screw axis of the screw. This rotation results in one or both nuts moving along the screw. Movement between the first nut and the second nut along the screw adjusts a distance between the first mounting point and the second mounting point.

Abstract: A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.

Abstract: Compositions and methods for development of potent siRNA therapeutics for prevention and treatment of Corona Virus (2019-nCoV; COVID-19) infections are provided. The compositions include a pharmaceutical composition comprising siRNA cocktails that target critical viral genes and pharmaceutically acceptable polymeric nanoparticle carriers and liposomal nanoparticle carriers. Administration methods for prevention and treatment are provided, including airway instillation, subcutaneous injections and nebulizer aerosolization.

Abstract: At least one example embodiment relates to a container. The container includes a base, a canister configured to engage a portion of the base, and a lid configured to be removably coupled to the canister such that the lid is moveable between a locked position and an unlocked position. The base includes a bottom wall having a central portion, a peripheral portion, and an angle portion between the central portion and the peripheral portion. The base includes a first sidewall extending from a periphery of the peripheral portion and about a periphery of the bottom wall and a second sidewall extending from an end of the peripheral portion opposite the first sidewall. The first sidewall and the second sidewall extend perpendicular to the peripheral portion such that the peripheral portion, first sidewall, and second sidewall define a first gap.

Abstract: An improved system and method of determining a low water and/or water-out condition in a humidifier chamber of a respiratory or surgical humidifier system can use a specific frequency band to detect changes in a temperature of a heater plate. The temperature changes can correlate to the specific heat capacity value of the humidifier chamber. The low water and/or water-out detection process can be performed without having to determine the gases flow rate and/or can be run continuously. A heater plate assembly of the system can include a compliant insulation sheet to improve thermal coupling between the heating element and the top heating plate of the heater plate assembly, thereby improving the low water and/or water-out detection process.

Abstract: Examples are disclosed herein that relate to vehicles, composite parts, and methods for forming a composite part for a vehicle. In one example, a vehicle comprises a composite part comprising a skin comprising one or more material layers. The composite part further comprises a stiffener comprising one or more material layers, wherein the stiffener comprises a flange and a web. The composite part also includes an additively manufactured sub-structure positioned between at least a portion of the skin and at least a portion of the stiffener. The additively manufactured sub-structure comprises at least one flange portion, at least one radius, and at least one radius filler. A polymer matrix is co-infused within the skin, the stiffener, and the additively manufactured sub-structure.

Abstract: A system and method for machine learning architecture for prospective resource allocations are described. The method may include: receiving data records representing historical resource allocations from a user account associated with a first identifier to a resource account associated with a second identifier; deriving input features based on the data records; computing, using a trained neural network architecture, a predicted resource allocation amount and a predicted resource allocation date for the predicted resource allocation amount based on the derived input features; determining, using the trained neural network architecture, a first selection score associated with the predicted resource allocation amount and a second selection score associated with the predicted resource allocation date; and when the first or second selection score is above a minimum threshold, causing to display, at a display device, the associated resource allocation amount or date corresponding to the second identifier.

Abstract: siRNA molecules targeting AGT mRNA that reduce or inhibit AGT production are provided. Pharmaceutical compositions containing such siRNA molecules also are provided, together with methods of their use for treating hypertension. Pharmaceutical compositions containing at least one oligonucleotide covalently linked to, and delivered to a target cell by, a peptide docking vehicle (PDoV) are capable of reducing or inhibiting the production of AGT and treating hypertension. The PDoV may contain a targeting ligand such as a GalNAc moiety conjugated to the PDoV which targets the complex to hepatocytes.

Abstract: Systems and techniques for determining a sideslip vector for a vehicle that may have a direction that is different from that of a heading vector for the vehicle. The sideslip vector in a current vehicle state and sideslip vectors in predicted vehicles states may be used to determine paths for a vehicle through an environment and trajectories for controlling the vehicle through the environment. The sideslip vector may be based on a vehicle position that is the center point of the wheelbase of the vehicle and may include lateral velocity, facilitating the control of four-wheel steered vehicle while maintaining the ability to control two-wheel steered vehicles.

Abstract: A cleaner assembly for an apparatus for making pouch products includes a cleaner roller and a poker roller. The cleaner roller may counter rotate with a rotatable drum of the apparatus, in contact with an upper surface of a first elastic layer on the rotatable drum, and at a greater tangential speed than at least one surface of an outer circumferential surface of the rotatable drum or an upper surface of the first elastic layer. The poker roller includes projections that are each configured to extend into one or more divots of the rotatable drum. The poker roller may counter rotate with the rotatable drum and at a same tangential speed as the at least one surface such that the projections extend into and out of separate, respective divots of the rotatable drum based on the counter rotation of the poker roller and the rotatable drum.

Abstract: A humidification system can include a heater base, a humidification chamber, and a breathing circuit. A cartridge can be removably coupled to the heater base. The cartridge can include various sensors, probes, sensor wire connectors, heater wire connectors, and/or other features. The cartridge can include features configured to mate with corresponding features on the humidification chamber and the heater base. The cartridge includes a memory, such as an EEPROM, or other suitable storage device. When the cartridge is installed on the heater base, the memory is electrically connected to a processor and/or memory of the heater base. Various models of cartridges can be produced for use with different humidification chambers, breathing circuits, and/or therapies. A connector can be configured to couple an inspiratory conduit to an outlet port of the humidification chamber. The connector can provide a pneumatic connection to the outlet port and an electrical connection to the cartridge.

Abstract: A circuit connector for a humidification system, the system comprising a base unit configured to be engaged by a humidification chamber. The circuit connector comprises an inlet to fluidly connect to an outlet of the humidification chamber to receive humidified gases therefrom, an outlet to sealably connect to or integral with a conduit for directing the humidified gases to a user, and an electrical terminal for electrically coupling the circuit connector to an electrical terminal associated with the base unit. The circuit connector may be releasably and lockably connectable to the outlet of the humidification chamber and/or orientation features may control orientation of component parts of the system as they are assembled.

Abstract: An autonomous surface cleaning apparatus includes a body including a chassis and an outer shell mounted to the chassis, a drive system carried by the body, a cleaning assembly projecting forward beyond a front surface of the outer shell, the cleaning assembly having a generally planar front surface, and a forward bumper mounted to the front surface of the cleaning assembly. The apparatus further includes a plurality of forwardmost contact sensors disposed behind the forward bumper and arranged to detect displacement of the forward bumper relative to the cleaning assembly, a first plurality of shell contact sensors each being arranged to detect longitudinal displacement of the outer shell relative, and a second plurality of shell contact sensors each being arranged to detect lateral displacement of the outer shell relative to both the chassis and the cleaning assembly.

Abstract: Four-wheel steering of a vehicle, e.g., in which leading wheels and trailing wheels are steered independently of each other, can provide improved maneuverability and stability. Steering angle constraints may be used to limit or prevent saturation of steering by only one set of wheels as well as to reduce sideslip. The steering angle constraints are vehicle independent and applicable across a fleet of different vehicles based on vehicle speed. For instance, the steering angle constraints establish angle limits that dynamically adjust based on vehicle speed to ensure vehicle velocity and acceleration remain within predefined limits as established by autonomous vehicle system design.

Abstract: There is provided a mobile robot including a chassis, a drive system, and a collision detection system. The collision detection system includes first and second parts of the mobile robot, the first and second body parts being disconnected and moveable relative to the chassis in response to a collision with an object, and first and second sensors configured to sense relative movement between the chassis and the first and second body parts respectively and, in a collision event, to send a control signal causing the drive system to take corrective action. The mass of the second body part is substantially lower than the mass of the first body part.

Abstract: A method of data storage includes determining a latency distance from a primary node to each of two or more replica nodes, choosing a preferred replica node of the two or more replica nodes based on the determined latency distances, and write-caching data into the preferred replica node.

Abstract: A cleaner assembly for an apparatus for making pouch products includes a cleaner roller and a poker roller. The cleaner roller may counter rotate with a rotatable drum of the apparatus, in contact with an upper surface of a first elastic layer on the rotatable drum, and at a greater tangential speed than at least one surface of an outer circumferential surface of the rotatable drum or an upper surface of the first elastic layer. The poker roller includes projections that are each configured to extend into one or more divots of the rotatable drum. The poker roller may counter rotate with the rotatable drum and at a same tangential speed as the at least one surface such that the projections extend into and out of separate, respective divots of the rotatable drum based on the counter rotation of the poker roller and the rotatable drum.