Abstract: Provided are: a copolymer for rheological or cosmetic compositions and, a composition thereof, and methods of making and using the same. Said copolymer comprises a) a first acrylic ester as monomer A, said monomer A being a branched acrylic ester; b) at least one further acrylic ester as monomer B, said monomer B being a linear acrylic ester; c) a cyclic N-vinyl amide as monomer C; d) at least one compound comprising a radically polymerizable ?.?-ethylenically un-saturated double bond and at least one cationic and/or cationogenic moiety said compound being monomer D; e) at least one monoethylenically unsaturated carboxylic acid as monomer E; with the monomer B in its polymerized form having a glass transition temperature of 24° C. or lower and making at most one third of the weight amount of monomer A.

Abstract: Methods of using azide-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to inhibit infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. Also, provided are methods of tracking a virus in vivo, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The azide-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome.

Abstract: A process and apparatus for separating a feed containing hydrogen, carbon monoxide, methane, and optionally nitrogen to form a product gas having a desired H2:CO molar ratio and optionally a hydrogen product gas and a carbon monoxide product gas. The feed is partially condensed to form a hydrogen-enriched vapor fraction and a carbon monoxide-enriched liquid fraction. The hydrogen-enriched vapor fraction and carbon monoxide-enriched liquid fraction are combined in a regulated manner to form an admixture, which is cryogenically separated to form the product mixture having the desired H2:CO molar ratio.

Abstract: A device and method for correcting a rotational deformity, for use in lengthening a bone or aiding in stabilising a fractured bone. When used to correct a rotational deformity, the device comprises a first member and a second member moveably connected to each other such that when the two members are moved apart along a first axis, the first and/or second members rotate relative to each other about the first axis.

Abstract: Methods of using viruses labeled with alkyne-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to increase the infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an alkyne-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The viruses labeled with alkyne-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome.

Abstract: The present invention relates to a method for making a copolymer comprising polymerizing the monomers in a solution comprising the monomers and a solvent, wherein the solvent comprises water and an alcohol. Furthermore, the present invention relates to the copolymer obtainable by this method (“the copolymer according to the present invention”) and to the use of the copolymer according to the present invention for styling or for fixing human hair. Furthermore, the present invention relates to the use of a more generally defined copolymer for styling or for fixing human hair, and for providing high gloss to the hair that is styled or fixed.

Abstract: A fluidic delivery device includes a fluid supply containing a fluid, the fluid supply has a fluid reservoir and a pair of fluid permeable compressible bodies located in the fluid reservoir. One of the fluid permeable compressible bodies has an effective greater density than the other fluid permeable compressible body.

Abstract: Disclosed herein are novel processes for the production of oligonucleotides that are suitable for use in the production of chemically modified oligonucleotides, such as those for use in therapy.

Abstract: An orthopaedic device for correcting deformities in a bone is disclosed, the device including first and second end portions to fix to first and second bone regions either side of a growth plate, and a connection portion extending between the first and second end portions. At least the first end portion can protrude relative to the connection portion such that it is at least partly receivable in a first recess formed in the first bone region. The first end portion can be in the form of an end cup and can be fixed to the first bone region by a fixation device such as a screw. A head of the screw can sit within the end cup. The second end portion can be similar to the first end portion or alternatively may comprise a hook, blade or staple.

Abstract: A fluidic delivery device includes a fluid supply containing a fluid, the fluid supply has a fluid reservoir and a pair of fluid permeable compressible bodies located in the fluid reservoir. One of the fluid permeable compressible bodies has an effective greater density than the other fluid permeable compressible body.

Abstract: Methods of using azide-modified biomolecules, such as fatty acids, carbohydrates and lipids, to treat a plant, an insect or an animal infected with a virus or to inhibit infectivity of a virus, such as the human immunodeficiency virus, are provided. Also provided are methods of labeling a virus, such as human immunodeficiency virus, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. Also, provided are methods of tracking a virus in vivo, with an azide-modified biomolecule, such as a fatty acid, a carbohydrate, or an isoprenoid lipid. The azide-modified biomolecules may be combined with a pharmaceutically acceptable excipient to produce a pharmaceutical composition, optionally containing another anti-viral agent and/or a delivery agent, such as a liposome.

Abstract: A system, optical assembly, and optical communication system are disclosed. The optical assembly is disclosed as including an optoelectronic component having a predetermined shape and an optical module that permits light emitted by the optoelectronic component or travelling to the optoelectronic component to pass therethough. The optical module is further disclosed as including a first surface and an opposing second surface, the first surface of the optical module including a first mating feature to receive the optoelectronic component, and the second surface of the optical module including a receptacle to receive and align an optical fiber with the optoelectronic component.

Abstract: A planar bait presenting device is described comprising a bait contact zone for receiving bait wherein the bait contact zone comprises a dose measurement guide and an ink display zone. A kit is also described comprising a plurality of the bait presenting devices and a backing sheet to which the devices are removably adhered. A method of displaying bait, is described which comprises adhering the device to a surface; and applying a discrete amount of bait to the bait contact zone. The method involves applying bait to the bait contact zone until the area defined by the dose measurement guide is substantially covered with bait. Also described are methods of displaying bait which comprise adhering the device to a surface and exposing a discrete amount of bait in the bait contact zone; and methods of enclosing bait in a hole which comprise inserting a discrete amount of bait into a hole and adhering the device to the surface surrounding the hole, thereby enclosing the bait in a hole.

Abstract: Compounds of formula (I) inhibit HDAC activity: wherein A, B and D independently represent ?C— or ?N—; W is a divalent radical —CH?CH— or CH2CH2—; R1 is an ester group; R2 is the side chain of a natural or non-natural alpha-amino acid; z is 0 or 1; and Y, L1, and X1 are as defined in the claims.

Abstract: A method of changing the angle of the seat of a saddle used for riding horses. This invention requires a removable or detachable seat cover under which is a flexible seat, front of which may be raised or lowered for maximum rider comfort. This is achieved by using spacers under the front of the seat structure, which is called a ground seat, in saddle making nomenclature. This invention allows saddle seat configuration to be optimized for different riding conditions or disciplines, which traditionally use saddles that have differing seat angles, to optimize rider position and comfort for that discipline.

Abstract: Systems, methods, and devices relating to tracking a vehicle on its journey. At predetermined reporting time intervals, the vehicle's location is determined using GNSS and a current vector is calculated based on a current location and an immediately preceding location. The difference between the current vector and the immediately preceding vector is then determined and this difference is stored in the data packet. The data packet is transmitted to the base station using a two-way radio data link at select predetermined transmission time intervals. The data in the data packet is encoded to minimize the number of bits needed to store each data point.

Abstract: A system, optical assembly, and optical communication system are disclosed. The optical assembly is disclosed as including an optoelectronic component having a predetermined shape and an optical module that permits light emitted by the optoelectronic component or travelling to the optoelectronic component to pass therethough. The optical module is further disclosed as including a first surface and an opposing second surface, the first surface of the optical module including a first mating feature to receive the optoelectronic component, and the second surface of the optical module including a receptacle to receive and align an optical fiber with the optoelectronic component.

Abstract: Covalent conjugates of an ?,?-disubstituted glycine ester and a modulator of the activity of a target intracellular enzyme or receptor, wherein the ester group of the conjugate is hydrolysable by one or more intracellular carboxylesterase enzymes to the corresponding acid and the ?,?-disubstituted glycine ester is conjugated to the modulator at a position remote from the binding interface between the inhibitor and the target enzyme or receptor pass into cells and the active acid hydrolysis product accumulates within the cells, as in the following compound:

Abstract: A medical device may include a shaft, and a first tool extending from a distal end of the shaft. The medical device also may include a control assembly coupled to the shaft. The control assembly may include a console, a first grip extending proximally from the console, and a second grip extending proximally from the console. The control assembly also may include a first deflection actuator configured to deflect the first tool about a longitudinal axis of the first tool, a first rotation actuator configured to rotate the first tool about the longitudinal axis of the first tool, and a first longitudinal actuator configured to move the first tool along the longitudinal axis of the first tool.