Patents by Inventor David Gunther

David Gunther has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10968216
    Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: April 6, 2021
    Assignees: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGESELLSCHAFT, THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE GENERAL HOSPITAL CORPORATION
    Inventors: Stefan Nikolaus Gradl, Duy Nguyen, Knut Eis, Judith Günther, Timo Stellfeld, Andreas Janzer, Sven Christian, Thomas Mueller, Sherif El Sheikh, Han Jie Zhou, Changjia Zhao, David B. Sykes, Steven James Ferrara, Kery Liu, Simon Anthony Herbert, Claudia Merz, Michael Niehues, Carl Friedrich Nising, Martina Schäfer, Katja Zimmermann, Jörg Knäblein, Kai Thede, Thomas Faupel
  • Publication number: 20210017639
    Abstract: Apparatus and methods for controlling plasma profiles during PVD deposition processes are disclosed. Some embodiments utilize EM coils placed above the target to control the plasma profile during deposition.
    Type: Application
    Filed: July 16, 2020
    Publication date: January 21, 2021
    Applicant: Applied Materials, Inc.
    Inventors: Alexander Jansen, Keith A. Miller, Prashanth Kothnur, Martin Riker, David Gunther, Emily Schooley
  • Patent number: 10874422
    Abstract: Described here are devices, systems, and methods for improving blood flow in a vessel. Generally, the method may comprise advancing a catheter into a first vessel proximal to an occlusion in the first vessel and forming a fistula between the first vessel and a second vessel. This may deliver blood flow around an occlusion to ischemic tissues located in the peripheral vasculature.
    Type: Grant
    Filed: January 15, 2017
    Date of Patent: December 29, 2020
    Assignee: TVA Medical, Inc.
    Inventors: William E. Cohn, Thomas D. Pate, Philip M. Tetzlaff, David Gunther
  • Publication number: 20200377472
    Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: August 18, 2020
    Publication date: December 3, 2020
    Applicants: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGELLSCHAFT, THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE GENERAL HOSPITAL CORPORATION
    Inventors: Stefan Nikolaus GRADL, Duy NGUYEN, Knut EIS, Judith GÜNTHER, Timo STELLFELD, Andreas JANZER, Sven CHRISTIAN, Thomas MÜLLER, Sherif El SHEIKH, Han Jie ZHOU, Changjia ZHAO, David B. SYKES, Steven James FERRARA, Kery LIU, Michael KRÖBER, Claudia MERZ, Michael NIEHUES, Martina SCHÄFER, Katja ZIMMERMANN, Carl Friedrich NISING
  • Patent number: 10815215
    Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: October 25, 2017
    Date of Patent: October 27, 2020
    Assignees: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGELLSCHAFT, THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE GENERAL HOSPITAL CORPORATION
    Inventors: Stefan Nikolaus Gradl, Duy Nguyen, Knut Eis, Judith Günther, Timo Stellfeld, Andreas Janzer, Sven Christian, Thomas Müller, Sherif El Sheikh, Han Jie Zhou, Changjia Zhao, David B. Sykes, Steven James Ferrara, Kery Liu, Michael Kröber, Claudia Merz, Michael Niehues, Martina Schäfer, Katja Zimmermann, Carl Friedrich Nising
  • Patent number: 10779466
    Abstract: A cutter head for a brushcutter has a base member with top and bottom base member parts and rotates about an axis of rotation in operation. The top base member part is fixed to the brushcutter shaft end. The bottom base member part is screwed by a screw element to the shaft end. A bearing element is arranged in the base member radially spaced to the axis of rotation. A cutting tool is secured by the bearing element to the base member between top and bottom base member parts. The bearing element is secured either to bottom or top base member part and arranged relative to the other one such that the bearing element is constructively unhindered to move relative to the other base member part at least circumferentially and such that the bottom base member part for mounting or demounting is rotatable relative to the top base member part.
    Type: Grant
    Filed: February 7, 2018
    Date of Patent: September 22, 2020
    Assignee: Andreas Stihl AG & Co. KG
    Inventor: David Günther
  • Publication number: 20200289149
    Abstract: Described here are devices, systems, and methods for improving blood flow in a vessel. Generally, the method may comprise advancing a catheter into a first vessel proximal to an occlusion in the first vessel and forming a fistula between the first vessel and a second vessel. This may deliver blood flow around an occlusion to ischemic tissues located in the peripheral vasculature.
    Type: Application
    Filed: April 1, 2020
    Publication date: September 17, 2020
    Applicant: TVA Medical, Inc.
    Inventors: William E. Cohn, Thomas D. Pate, Philip M. Tetzlaff, David Gunther
  • Patent number: 10694663
    Abstract: A rotatingly drivable filament cutting head for a trimmer, having a basic body on which a cutting filament is held. The cutting filament extends from outside the basic body through an opening into an interior region of the filament cutting head open to the surrounding area. A stop is arranged on the filament cutting head, so that, in a first position of the cutting filament, the stop delimits a filament portion of the cutting filament, which is insertable into the interior region, to an insertion length. A deflection element is arranged in the interior region so that the cutting filament can be switched from its first position, without the cutting filament being longitudinally displaced, into a second position. The cutting filament abuts against the deflection element in its second position and the stop does not delimit the length of the filament portion which is insertable into the interior region.
    Type: Grant
    Filed: May 9, 2018
    Date of Patent: June 30, 2020
    Assignee: ANDREAS STIHL AG & CO. KG
    Inventors: Sven Lang, David Günther
  • Publication number: 20200194243
    Abstract: Embodiments of a process kit are provided herein. In some embodiments, a process kit includes a deposition ring configured to be disposed on a substrate support, the deposition ring including an annular band configured to rest on a lower ledge of the substrate support, the annular band having an upper surface and a lower surface, the lower surface including a step between a radially inner portion and a radially outer portion; an inner lip extending upwards from the upper surface of the annular band and adjacent an inner surface of the annular band, wherein a depth between an upper surface of the annular band and a horizontal portion of the upper surface of the inner lip is between about 6.0 mm and about 12.0 mm; a channel disposed radially outward of and beneath the annular band; and an outer lip extending upwardly and disposed radially outward of the channel.
    Type: Application
    Filed: December 17, 2018
    Publication date: June 18, 2020
    Inventors: DAVID GUNTHER, CHENG-HSIUNG TSAI, KIRANKUMAR NEELASANDRA SAVANDAIAH
  • Patent number: 10662800
    Abstract: A gas turbine with a compressor, in which air can be compressed; with at least one burner having a combustion chamber, which can be supplied with the compressed air and in which a fuel can be combusted in the presence of the compressed air subject to heating the air; a turbine, in which the heated air can be expanded; a diffuser arranged, seen in flow direction of the expanded air, downstream of the turbine; a plurality of temperature sensors, dependent on the measurement values of which a thermodynamic mean temperature or mixed-out turbine outlet temperature of the expanded air can be determined. The temperature sensors are arranged in the region of a diffuser cover, which at an outlet end of the diffuser closes off a hollow space of the diffuser positioned radially inside of a flow duct of the diffuser.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: May 26, 2020
    Assignee: MAN Energy Solutions SE
    Inventors: Christian Günther, David Kluβ, Jaman El Masalme
  • Publication number: 20200123129
    Abstract: The present invention provides triazolone compounds of general formula (I): in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: October 25, 2017
    Publication date: April 23, 2020
    Applicants: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGELLSCHAFT, THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE GENERAL HOSPITAL CORPORATION
    Inventors: Stefan Nikolaus GRADL, Duy NGUYEN, Knut EIS, Judith GÜNTHER, Timo STELLFELD, Andreas JANZER, Sven CHRISTIAN, Thomas MÜLLER, Sherif El SHEIKH, Han Jie ZHOU, Changjia ZHAO, David B. SYKES, Steven James FERRARA, Kery LIU, Michael KRÖBER, Claudia MERZ, Michael NIEHUES, Martina SCHÄFER, Katja ZIMMERMANN, Carl Friedrich NISING
  • Publication number: 20190375747
    Abstract: The present invention provides triazolone compounds compounds of general formula (I): in which R1, R2, R3, R4 and R5 are as defined herein, methods of preparing said compounds, intermediate compounds useful for preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of hyperproliferative disorders, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: October 25, 2017
    Publication date: December 12, 2019
    Applicants: BAYER AKTIENGESELLSCHAFT, BAYER PHARMA AKTIENGELLSCHAFT, THE BROAD INSTITUTE, INC., PRESIDENT AND FELLOWS OF HARVARD COLLEGE, THE GENERAL HOSPITAL CORPORATION
    Inventors: Stefan Nikolaus GRADL, Duy NGUYEN, Knut EIS, Judith GÜNTHER, Timo STELLFELD, Andreas JANZER, Sven CHRISTIAN, Thomas MUELLER, Sherif El SHEIKH, Han Jie ZHOU, Changjia ZHAO, David B. SYKES, Steven James FERRARA, Kery LIU, Simon Anthony HERBERT, Claudia MERZ, Michael NIEHUES, Carl Friedrich NISING, Martina SCHÄFER, Katja ZIMMERMANN, Jörg KNÄBLEIN, Kai THEDE, Thomas FAUPEL
  • Patent number: 10194584
    Abstract: The cutting knife has a base member with first and second faces. One face has a topographic disturbance element arranged between knife edge and longitudinal center axis and shaping the elevation profile of the face. On the opposite face relative to the center plane an opposite elevation profile with contour line is formed. The contour line points of the contour line of the first elevation profile are positioned opposite the contour line points of the opposite contour line on perpendiculars to the center plane. The contour line of the first elevation profile and the opposite contour line are noncongruent. The contour line of the first elevation profile extends transversely to the longitudinal center axis of the base member across the disturbance element and has an ascending line section and a descending line section. A turning point positioned between these line sections is a component of the disturbance element.
    Type: Grant
    Filed: January 18, 2017
    Date of Patent: February 5, 2019
    Assignee: Andreas Stihl AG & Co. KG
    Inventors: David Günther, Fabian Pöhler
  • Publication number: 20180325023
    Abstract: A rotatingly drivable filament cutting head for a trimmer, having a basic body on which a cutting filament is held. The cutting filament extends from outside the basic body through an opening into an interior region of the filament cutting head open to the surrounding area. A stop is arranged on the filament cutting head, so that, in a first position of the cutting filament, the stop delimits a filament portion of the cutting filament, which is insertable into the interior region, to an insertion length. A deflection element is arranged in the interior region so that the cutting filament can be switched from its first position, without the cutting filament being longitudinally displaced, into a second position. The cutting filament abuts against the deflection element in its second position and the stop does not delimit the length of the filament portion which is insertable into the interior region.
    Type: Application
    Filed: May 9, 2018
    Publication date: November 15, 2018
    Inventors: Sven LANG, David GÜNTHER
  • Publication number: 20180220583
    Abstract: A cutter head for a brushcutter has a base member with top and bottom base member parts and rotates about an axis of rotation in operation. The top base member part is fixed to the brushcutter shaft end. The bottom base member part is screwed by a screw element to the shaft end. A bearing element is arranged in the base member radially spaced to the axis of rotation. A cutting tool is secured by the bearing element to the base member between top and bottom base member parts. The bearing element is secured either to bottom or top base member part and arranged relative to the other one such that the bearing element is constructively unhindered to move relative to the other base member part at least circumferentially and such that the bottom base member part for mounting or demounting is rotatable relative to the top base member part.
    Type: Application
    Filed: February 7, 2018
    Publication date: August 9, 2018
    Inventor: David Günther
  • Publication number: 20170208740
    Abstract: The cutting knife has a base member with first and second faces. One face has a topographic disturbance element arranged between knife edge and longitudinal center axis and shaping the elevation profile of the face. On the opposite face relative to the center plane an opposite elevation profile with contour line is formed. The contour line points of the contour line of the first elevation profile are positioned opposite the contour line points of the opposite contour line on perpendiculars to the center plane. The contour line of the first elevation profile and the opposite contour line are noncongruent. The contour line of the first elevation profile extends transversely to the longitudinal center axis of the base member across the disturbance element and has an ascending line section and a descending line section. A turning point positioned between these line sections is a component of the disturbance element.
    Type: Application
    Filed: January 18, 2017
    Publication date: July 27, 2017
    Inventors: David Günther, Fabian Pöhler
  • Publication number: 20170202603
    Abstract: Described here are devices, systems, and methods for improving blood flow in a vessel. Generally, the method may comprise advancing a catheter into a first vessel proximal to an occlusion in the first vessel and forming a fistula between the first vessel and a second vessel. This may deliver blood flow around an occlusion to ischemic tissues located in the peripheral vasculature.
    Type: Application
    Filed: January 15, 2017
    Publication date: July 20, 2017
    Inventors: William E. COHN, Thomas D. PATE, Philip M. TETZLAFF, David GUNTHER
  • Patent number: 8939465
    Abstract: A restraint system (120, 120a) for protecting at least one aircraft occupant, the aircraft including a cabin having at least one seat (54, 56, 58) facing a longitudinal center line of the aircraft, the restraint system including a first airbag (162) inflatable from a stored position to an inflated position, the airbag when inflated being adjacent the seated occupant and located on a side of the occupant facing the front of the aircraft, the airbag reducing occupant movement toward the front of the aircraft and cushioning the occupant from any impact, the system also includes a mechanism (222, 240) to lessen movement of the lower legs of the occupant.
    Type: Grant
    Filed: July 18, 2012
    Date of Patent: January 27, 2015
    Assignee: Key Safety Systems, Inc.
    Inventors: Kurt Kastelic, John P. Wallner, David Gunther, Sr.
  • Patent number: D888903
    Type: Grant
    Filed: December 17, 2018
    Date of Patent: June 30, 2020
    Assignee: APPLIED MATERIALS, INC.
    Inventors: David Gunther, Cheng-Hsiung Tsai, Kirankumar Neelasandra Savandaiah
  • Patent number: D908645
    Type: Grant
    Filed: August 26, 2019
    Date of Patent: January 26, 2021
    Assignee: APPLIED MATERIALS, INC.
    Inventors: Kirankumar Neelasandra Savandaiah, David Gunther, Siew Kit Hoi