Abstract: Disclosed herein are methods and systems for integrating an enterprise's structured and unstructured data to provide users and enterprise applications with efficient and intelligent access to that data. In accordance with exemplary embodiments, the generation of classification information about unstructured data can be hardware-accelerated by processing streaming unstructured data through a reconfigurable logic device, a graphics processor unit (GPU), or chip multi-processor (CMP) to generate the classification metadata about the unstructured data.

Abstract: Provided herein are compounds according to Formulas (I) or (II) and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various methods, including treating cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease, osteoarthritis, idiopathic pulmonary fibrosis and neurological conditions/disorders/diseases.

Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: Methods for loading a module on a plurality of device types without modification includes initializing an application native to the client device, the application including a web browser; determining a module to be loaded on the application, the module written in a web-based format and having a set of dependencies indicated within a code thereof; and loading the determined module on the web browser for recognition by the application native to the client device. The loading the determined module on the web browser includes loading the set of dependencies of the module.

Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: A rotating tapering cone or tube is used for separating liquid from trash. The cone or tube is constructed of either a wire mesh or parallel slats. The cone or tube is located in a complete trash disposal system. At the front of the system there is a trash intake funnel which delivers the trash to a device for shredding the trash which will deliver the shredded trash to the tapered cone including a high speed air stream. The tube is rotated at a high rate of speed whereby any fluid in the shredded trash will be expelled through the surface of the tube by way of a centrifugal and an intensive air speed.

Abstract: A fluid drain may include a fluid reservoir comprising a lower tube inlet that opens into the fluid reservoir, a lower tube at least partially positioned within the lower tube inlet, and an upper tube at least partially positioned within the lower tube. The fluid drain may further include an upper tube clamp having an opening therein, wherein the upper tube is positioned within the opening in the upper tube clamp and the upper tube clamp is configured to remain attached to the upper tube upon removal of the upper tube from the lower tube.

Abstract: Endotracheal tube coupling adapters for facilitating collection and removal of biofilm or any debris from endotracheal tubes for disposal or laboratory testing are disclosed. The endotracheal tube coupling adapters may be adapted for use in closed suction systems. The endotracheal tube coupling adapters may be configured to remain coupled to an endotracheal tube from the time of intubation until the time of removal and to receive visualization, cleaning, and/or biofilm collection devices or members without being removed from the endotracheal tube.

Abstract: Provided herein are compounds according to Formula I and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various methods, including treating cancers such as colon, ovarian, pancreatic, breast, liver, prostate and hematologic cancers:

Abstract: The invention relates to modified polymerase enzymes which exhibit improved incorporation of nucleotide analogs bearing substituents at the 3? position of the sugar moiety that are larger in size than the naturally occurring 3? hydroxyl group. Also described are methods of using the polymerases to incorporate nucleotides into polynucleotides, particularly in the context of DNA sequencing.

Abstract: The automated switching of broadcast sources of an audio content stream based on the geographic location of the physical unit that is receiving the audio content stream. For instance, while rendering a particular audio content stream from a first broadcasting source, a system may have an identity of one or more alternative possible broadcasting sources available for the same audio content stream for that relative geographic location. In response to some decision making, the system may decide to switch broadest sources for that audio content stream. Thus, the user continues to listen to the audio content stream without being subject to possible negative consequences of continuing to listen to the audio content stream as received from the original broadcast station. Data transmitted by the broadcast stations themselves need not be relied upon. Thus, the automated switching is accomplished even outside of regions in which broadcast stations transmit such data.

Abstract: Methods and computer readable medium for collaborating on geographical maps between two or more computers are disclosed. In particular, sharing a geographical location on a map between two or more computers and co-navigating a map between two or more computers are disclosed. With respect to sharing a geographical location, the geographical location is retrieved to the first computer. The geographical location is added to the map being rendered at the first computer and is sent to a second computer. A map including the geographical location is rendered at the second computer. With respect to co-navigating, a map is displayed from a map perspective at the first computer. The map perspective is sent to the second computer. A map from the same map perspective being displayed at the first computer is rendered at the second computer.

Abstract: A product retrieval mechanism for vending machines that permits collection of varying size products at a first level yet presents such products for collection at a raised height to make retrieval more convenient. The retrieval mechanism utilizes a movable floor within the hopper that movable between a lowered position and a higher position for presenting the product at a higher retrieval point relative to the floor upon opening of the hopper.

Abstract: Disclosed herein is a method and system for integrating an enterprise's structured and unstructured data to provide users and enterprise applications with efficient and intelligent access to that data. In accordance with exemplary embodiments, the generation of metadata indexes about unstructured data can be hardware-accelerated by processing streaming unstructured data through a reconfigurable logic device to generate the metadata about the unstructured data for the index.

Abstract: An electrical drive system includes an electric motor having an armature, which is mounted on a stator, and a rotor, wherein aligning stator flux with rotor flux enables current to flow in the armature without inducing torque on the rotor shaft. The disclosed operation may be used, for example, in testing the electrical drive system. The electric drive system can carry full rated current yet produce little or no torque, thereby increasing the current that can be tested during electrical drive test procedures without producing undesired forces or motion. The method may be used, for example, in heating the electric motor, for example for de-icing.

Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases due to mutations in Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: A method for bonding the tail of a convolutely wound log to the body is provided. The method comprises the use of a nonadhesive phase-change material to mechanically bond the tail to the wound log. The nonadhesive phase-change material is heated to an amorphous state prior to its application. Once applied to the wound log, the nonadhesive phase-change material mechanical bonds with the tail and wound log and as heat is lost, changes to a non-amorphous state. The mechanical bond can be selectively reversed through the application of a strength degradation accelerator.