Abstract: In various embodiments, there is provided a luminaire optical system that includes a first optical module and a second optical module. The first optical module includes a first reflective surface configured to output light vectors in a first direction. The second optical module includes a second reflective surface configured to reflect light vectors from the second optical module in a second direction. The first reflective surface and the second reflective surfaces are surfaces of one reflector.

Abstract: An absorbent article selected from a sanitary napkin, an incontinence pad and a pantyliner, comprising a topsheet layer a backsheet layer a fastening adhesive applied on the backsheet garment facing surface, wherein at least a portion of said fastening adhesive (PFA) is applied in a pattern and wherein said backsheet layer is a plastic film having a basis weight of less than 20 gsm.

Abstract: A user interface system for providing insurance including: a media capture unit including a camera; a controller in communication with the media capture unit; and a memory in communication with the controller; wherein the memory includes first asset information previously captured by an asset verification process in which a user captures first visual media information including at least one visual media information including an asset shown from a perspective, wherein the memory additionally including an asset verification software application that, when executed by the controller, causes the controller to: in response to receiving a notification of a loss regarding the asset, prompt the user to capture second asset information using a media prompt including directions for capturing at least one image including a view of the asset from the perspective; and transmit the second asset information to an underwriting server.

Abstract: A spark plug arrangement is disclosed for use in an engine system. The spark plug arrangement may include a body, and a cap fixedly connected to the body to form an integral pre-chamber. The cap may have at least one orifice. The spark plug arrangement may also include an electrode extending through the body and at least partially into the pre-chamber. The electrode may be configured to create a spark in the pre-chamber. The spark plug arrangement may further include a capillary tube disposed within the body and configured to inject gaseous fuel into the pre-chamber to form an air and fuel mixture to be ignited by the spark in the pre-chamber.

Abstract: Methods and computer readable medium for collaborating on geographical maps between two or more computers are disclosed. In particular, sharing a geographical location on a map between two or more computers and co-navigating a map between two or more computers are disclosed. With respect to sharing a geographical location, the geographical location is retrieved to the first computer. The geographical location is added to the map being rendered at the first computer and is sent to a second computer. A map including the geographical location is rendered at the second computer. With respect to co-navigating, a map is displayed from a map perspective at the first computer. The map perspective is sent to the second computer. A map from the same map perspective being displayed at the first computer is rendered at the second computer.

Abstract: This invention presents a method for overcoming limitation in brightness and heating effects for LED based Precision Approach Path Indicators and allowing both colors to be imaged in the far field with the proper abrupt transition between the red and white sectors. This method relies on the use of linear arrays of LED's and cylindrical optics.

Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases due to mutations in Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: A shroud panel (60) is attached to a wing skin overhang (28) by a series of pivoting butt straps (86) to permit relative strains to occur.

Abstract: Provided herein are compounds according to Formula I and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various methods, including treating cancers such as colon, ovarian, pancreatic, breast, liver, prostate and hematologic cancers:

Abstract: Systems, methods and apparatus for capturing at least one audio signal using a plurality of microphones that generate a plurality of representations of the at least one audio signal. In some embodiments, the plurality of microphones are disposed in a multiple-microphone setting so that the at least one audio signal is captured by at least two of the plurality of microphones. In some embodiments, at least one of the plurality of microphones is a microphone of a mobile device. The plurality of representations of the at least one audio signal may be processed to obtain a processed representation of the at least one audio signal.

Abstract: The present application discloses a compound which is which activates Wnt/?-catenin signaling and thus treats or prevents diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.

Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: A hot melt adhesive dispensing unit includes an adhesive supply for receiving solid or semi-solid hot melt adhesive material, an adhesive supply heater associated with the adhesive supply for melting the solid or semi-solid hot melt adhesive material into a liquid hot melt adhesive material, a manifold connected to the adhesive supply and including a flow rate sensor for measuring a flow rate of the liquid hot melt adhesive material, the flow rate sensor generating flow rate information, a pump connected to the manifold for pumping liquid hot melt adhesive material from the adhesive supply into the manifold, the pump including a pump motor, and a variable frequency drive for controlling the pump motor. The variable frequency drive is in communication with the flow rate sensor for receiving the flow rate information and the pump motor for controlling the speed of the pump motor.

Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: An article having a longitudinal axis and a lateral axis, the article comprising a topsheet and a backsheet, wherein the topsheet comprises an apertured film and the backsheet comprises a film, wherein the topsheet film and the backsheet film are bonded via a plurality of adhesive stripes.

Abstract: Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: Azaindazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.