Abstract: Methods of delivering bone cement to within a vertebral body. An access cannula is directed into the vertebral body with a stylet disposed within a tube and extending through a valve in an open position. The stylet is removed from the access cannula such that the valve moves from the open position to a closed position in which the valve prevents egress of fluid from the access cannula. The bone cement is delivered through the access cannula with the valve in the open position. A delivery cannula may be directed into the access cannula, and the bone cement may be delivered through the delivery cannula. The delivery cannula may be prefilled with the bone cement. A bone cement mixer may be coupled to the access cannula and operated to direct the bone cement through the access cannula. Pressure from the bone cement may move the valve to the open position.

Abstract: Embodiments of a crimping device for crimping a radially expandable and compressible prosthetic valve are disclosed. A crimping device can comprise a housing configured to receive a prosthetic valve in a radially expanded state. The housing member can include a funnel segment and an outlet in communication with the funnel segment. The crimping device can further comprise an actuator rotatably coupled to the housing, wherein rotation of the actuator relative to the housing causes the prosthetic valve to move axially through the funnel segment such that at least a portion of the prosthetic valve compresses radially by engagement with the funnel segment and exits the crimping device via the outlet.

Abstract: A method includes identifying, using a machine learning model, beats and locations of peaks of the beats within electrocardiogram data. The method further includes determining heart rate over time based, at least in part, on the beats and the locations of the peaks. The method further includes displaying the heart rate over time and the locations of the peaks in single annotations on a graph.

Abstract: An amphiphilic block copolymer having any one of the formulas D-S—H, S(D)-H, S—H(D), D-S—H—S, D-S—H—S-D, S(D)-H—S, S(D)-H—S(D) or S—H(D)-S is disclosed. S is a hydrophilic block; H is a hydrophobic block; D is a drug molecule; ( ) denotes that the group is bonded directly or indirectly as a side chain or as part of a side chain group to the adjacent group; and the hyphen, “-” (or sometimes “-”), denotes that each of the adjacent S, H or D are linked either directly to one another or indirectly to one another via a linker, additionally wherein the hydrophilic block comprises a first hydrophilic monomer and the hydrophobic block comprises a first hydrophobic monomer and a second hydrophobic monomer.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: A system for monitoring and optimizing fuel consumption by a genset at an oil rig is described. Gensets require large amounts of fuel to initiate and to maintain in a standby, idling position. The system accesses data in a drill plan to determine the present and future power requirements and initiates gensets if needed; otherwise gensets can be shut down. Excess power can be stored in a power storage unit such as a capacitor, battery, or a liquid air energy storage unit.

Abstract: There are described devices and methods for use, for example, with signaling in a well, e.g. using a well structure of the well. Such signaling may include the communication of power and/or data signals. The devices and methods used may assist with efficient and/or effective communication of such signals. In some examples, there is described deployable devices and methods, e.g. a deployable device for signaling contact in a well, and methods associated therewith.

Abstract: Disclosed herein is a data storage device. A data port transmits data between a host computer system and the data storage device. A non-volatile storage medium stores encrypted user content data and a cryptography engine uses a cryptographic key to decrypt the encrypted user content data stored on the storage medium in response to a request from the host computer system. An access controller receives a request from a manager device to initialize the data storage device. The controller generates the cryptographic key, generates a manager key configured to provide manager access for the manager device and provide access to the cryptographic key, and stores, on a data store, authorization data indicative of the manager key and accessible based on a private key stored on the manager device.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: A coordinate positioning machine includes a plurality of drive axes, each being a rotary or linear drive axis, for positioning a platform within a working volume of the machine, and a separate linear counterbalance axis for counterbalancing the platform. With this arrangement the counterbalance axis can be substantially invariant to changes in orientation of the drive axes and can be counterbalanced by a simple counterweight. Also, an arrangement wherein the counterbalance axes and force generator are arranged so horizontal movement of the platform causes substantially no net movement of and/or no work to be done on the generator. Also, an arrangement wherein a series of counterbalance axes has at least one rotary counterbalance axis, and the generator is arranged behind or at a predetermined distance from the counterbalance axis. Also, an arrangement having a series of counterbalance axes with at most one rotary counterbalance axis between the generator and ground.

Abstract: Systems and methods that deliver a continuous partial nerve conduction block are described. A waveform generator can configure one or more direct current (DC) waveforms to provide a continuous partial nerve conduction block. One or more electrodes can deliver the one or more DC waveforms to provide the partial block to the neural structure. Feedback can be provided to the waveform generator related to the partial block. The feedback includes monitoring a property associated with the partial block and altering a parameter associated with the one or more direct current waveforms in response to the property associated with the partial block.

Abstract: Systems and methods described herein enforce access controls for network slices via proxy in a secure enclave of a user equipment (UE) device. A UE device executes, in a rich execution environment (REE), a function or application designated for using one or more secure network slices of a telecommunications network. The UE device executes, in a trusted execution environment (TEE), a slice admission control proxy (SACP) to perform admission control for the one or more secure network slices, and forces network traffic for the function or application through the SACP.

Abstract: Systems, methods, and computer-readable media provide techniques for on-demand access to object data hosted in distributed object storage. A query is received for the distributed object storage database, wherein the distributed object storage database includes first object data stored in a first data center at a first geographical location, and second object data stored in a second data center at a second geographical location. It is determined that the query is for at least a portion of the first object data stored by the first data center. The query is transmitted to a first computing device in the first data center. Results are received from the first computing device for the query, and the results are provided in response to the received query.

Abstract: A glass substrate with improved microLED transfer characteristics is disclosed, the glass substrate comprising a first major surface, a second major surface opposite the first major surface, and a thickness therebetween. An electrically functional layer may be disposed on the first major surface. The glass wafer exhibits a waviness with a magnitude less than or equal to about 1 ?m in a spatial wavelength range from about 0.25 mm to about 50 mm.

Abstract: Provided is a cord stopper for moving along a length of cord and releasably engaging the cord. The cord stopper comprises a body delimiting a channel for passing the cord through the body. A first path and a second path for the cord are defined in the channel. The first path or the second path is selectable by rotating the body relative to the cord. A cord engagement portion is provided along the first path, and a cord passing portion in the channel defines the second path. The cord engagement portion is configured to engage the cord such that movement of the cord stopper along the cord is restricted when the first path is selected. The cord passing portion is configured to permit the cord stopper to move along the length of the cord when the second path is selected. Further provided is a cord stopper assembly comprising the cord stopper and the cord.

Abstract: The present invention relates to a new class of compounds having an antiviral effect and the uses thereof.

Abstract: Apparatuses, systems, and methods for row hammer based cache lockdown. A controller of a memory may include an aggressor detector circuit which determines if addresses are aggressor addresses or not. The controller may include a tracker circuit which may count a number of times an address is identified as an aggressor, and may determine if the aggressor address is a frequent aggressor address based on the count. If the address is a frequent aggressor address, a cache entry associated with the frequent aggressor address may be locked (e.g., for a set amount of time). In some embodiments, the controller may include a second tracker which may determine if the frequent aggressor address is a highly attacked address. An address mapping associated with the highly attacked address may be changed.

Abstract: A method includes receiving a package of data comprising electrocardiogram (ECG) data and metadata. The metadata includes determined RR intervals associated with the ECG data. The method further includes displaying, on a user interface, at least a subset of the determined RR intervals and overriding the determined RR intervals associated with a time period that is greater than a time period associated with a selected RR interval.

Abstract: A method for generating a metallic particle slurry in a regenerator, the method comprising the steps of: (a) generating metallic particles on a surface of a cathode by applying a forward current for a forward current period; (b) displacing the metallic particles from the surface of the cathode by applying a displacement force for a displacement period; (c) dissolving residual metallic particles by applying a reverse current for a reverse current period; (d) providing a plurality of regenerator cells; and (e) establishing an airlock by isolating aqueous electrolyte between cavities of regenerator cells.

Abstract: Systems and methods are provided for delivering images to a patient before and/or during a medical procedure in which a patient is translated on a table relative to a gantry. In various example embodiments, images are projected to the patient while preserving the projected field size during table motion, thereby potentially reducing patient anxiety by providing a more immersive patient viewing experience. In some embodiments, the projected field size is maintained by a display system that is secured to the table such that both a projector and a projection screen are fixed relative to the table, and relative to the patient, during translation of the table. In some example embodiments, a reduction in patient anxiety may be achieved by projecting images as virtual images that are perceived by the patient as residing at a depth that lies beyond the confined spatial region in which the patient resides.