Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: A coordinate positioning machine includes a plurality of drive axes, each being a rotary or linear drive axis, for positioning a platform within a working volume of the machine, and a separate linear counterbalance axis for counterbalancing the platform. With this arrangement the counterbalance axis can be substantially invariant to changes in orientation of the drive axes and can be counterbalanced by a simple counterweight. Also, an arrangement wherein the counterbalance axes and force generator are arranged so horizontal movement of the platform causes substantially no net movement of and/or no work to be done on the generator. Also, an arrangement wherein a series of counterbalance axes has at least one rotary counterbalance axis, and the generator is arranged behind or at a predetermined distance from the counterbalance axis. Also, an arrangement having a series of counterbalance axes with at most one rotary counterbalance axis between the generator and ground.

Abstract: Systems and methods that deliver a continuous partial nerve conduction block are described. A waveform generator can configure one or more direct current (DC) waveforms to provide a continuous partial nerve conduction block. One or more electrodes can deliver the one or more DC waveforms to provide the partial block to the neural structure. Feedback can be provided to the waveform generator related to the partial block. The feedback includes monitoring a property associated with the partial block and altering a parameter associated with the one or more direct current waveforms in response to the property associated with the partial block.

Abstract: Systems and methods described herein enforce access controls for network slices via proxy in a secure enclave of a user equipment (UE) device. A UE device executes, in a rich execution environment (REE), a function or application designated for using one or more secure network slices of a telecommunications network. The UE device executes, in a trusted execution environment (TEE), a slice admission control proxy (SACP) to perform admission control for the one or more secure network slices, and forces network traffic for the function or application through the SACP.

Abstract: Systems, methods, and computer-readable media provide techniques for on-demand access to object data hosted in distributed object storage. A query is received for the distributed object storage database, wherein the distributed object storage database includes first object data stored in a first data center at a first geographical location, and second object data stored in a second data center at a second geographical location. It is determined that the query is for at least a portion of the first object data stored by the first data center. The query is transmitted to a first computing device in the first data center. Results are received from the first computing device for the query, and the results are provided in response to the received query.

Abstract: A glass substrate with improved microLED transfer characteristics is disclosed, the glass substrate comprising a first major surface, a second major surface opposite the first major surface, and a thickness therebetween. An electrically functional layer may be disposed on the first major surface. The glass wafer exhibits a waviness with a magnitude less than or equal to about 1 ?m in a spatial wavelength range from about 0.25 mm to about 50 mm.

Abstract: Provided is a cord stopper for moving along a length of cord and releasably engaging the cord. The cord stopper comprises a body delimiting a channel for passing the cord through the body. A first path and a second path for the cord are defined in the channel. The first path or the second path is selectable by rotating the body relative to the cord. A cord engagement portion is provided along the first path, and a cord passing portion in the channel defines the second path. The cord engagement portion is configured to engage the cord such that movement of the cord stopper along the cord is restricted when the first path is selected. The cord passing portion is configured to permit the cord stopper to move along the length of the cord when the second path is selected. Further provided is a cord stopper assembly comprising the cord stopper and the cord.

Abstract: The present invention relates to a new class of compounds having an antiviral effect and the uses thereof.

Abstract: Apparatuses, systems, and methods for row hammer based cache lockdown. A controller of a memory may include an aggressor detector circuit which determines if addresses are aggressor addresses or not. The controller may include a tracker circuit which may count a number of times an address is identified as an aggressor, and may determine if the aggressor address is a frequent aggressor address based on the count. If the address is a frequent aggressor address, a cache entry associated with the frequent aggressor address may be locked (e.g., for a set amount of time). In some embodiments, the controller may include a second tracker which may determine if the frequent aggressor address is a highly attacked address. An address mapping associated with the highly attacked address may be changed.

Abstract: A method includes receiving a package of data comprising electrocardiogram (ECG) data and metadata. The metadata includes determined RR intervals associated with the ECG data. The method further includes displaying, on a user interface, at least a subset of the determined RR intervals and overriding the determined RR intervals associated with a time period that is greater than a time period associated with a selected RR interval.

Abstract: A method for generating a metallic particle slurry in a regenerator, the method comprising the steps of: (a) generating metallic particles on a surface of a cathode by applying a forward current for a forward current period; (b) displacing the metallic particles from the surface of the cathode by applying a displacement force for a displacement period; (c) dissolving residual metallic particles by applying a reverse current for a reverse current period; (d) providing a plurality of regenerator cells; and (e) establishing an airlock by isolating aqueous electrolyte between cavities of regenerator cells.

Abstract: Systems and methods are provided for delivering images to a patient before and/or during a medical procedure in which a patient is translated on a table relative to a gantry. In various example embodiments, images are projected to the patient while preserving the projected field size during table motion, thereby potentially reducing patient anxiety by providing a more immersive patient viewing experience. In some embodiments, the projected field size is maintained by a display system that is secured to the table such that both a projector and a projection screen are fixed relative to the table, and relative to the patient, during translation of the table. In some example embodiments, a reduction in patient anxiety may be achieved by projecting images as virtual images that are perceived by the patient as residing at a depth that lies beyond the confined spatial region in which the patient resides.

Abstract: Systems, methods, and non-transitory computer-readable media can provide access to a first-level computing resource via a service catalog. In some instances, the first-level computing resource can be created by a first entity. Moreover, a second-level computing resource can be received. In some cases, the second-level computing resource can be created by a second entity based, at least in part, on the first-level computing resource. Access to the second-level computing resource can be provided via the service catalog. Relational information associated with the first-level computing resource and the second-level computing resource can be tracked.

Abstract: A method and apparatus physically partitions clean and dirty cache lines into separate memory partitions, such as one or more banks, so that during low power operation, a cache memory controller reduces power consumption of the cache memory containing the clean only data. The cache memory controller controls refresh operation so that data refresh does not occur for clean data only banks or the refresh rate is reduced for clean data only banks. Partitions that store dirty data can also store clean data, however other partitions are designated for storing only clean data so that the partitions can have their refresh rate reduced or refresh stopped for periods of time. When multiple DRAM dies or packages are employed, the partition can occur on a die or package level as opposed to a bank level within a die.

Abstract: Systems and methods for determining an alcohol by volume (ABV) measurement of liquids that are stored in containers in a storage facility are provided. The ABV is determined by measuring capacitance using one or more electrodes coupled to an outside wall of the storage container. Other environmental parameters can be taken into account, such as a temperature and humidity.

Abstract: Computing systems and methods of visually creating and visually analyzing proposed insurance or reinsurance constructs by providing an overall insurance or reinsurance structure creation and analysis system that includes an insurance/reinsurance visual design structure interface displayed to a user on a design construction user interface display presented to a user via a display of a user computing device having a user input device and the display having a plurality of coverage layer types visually illustrated on the design construction user interface display outside of a graphical diagram. The graphic diagram depicts at least one rectangular-shaped coverage structure layer that creates a proposed insurance or reinsurance construct and corresponds to one of the plurality of coverage layer types visually illustrated on the design construction user interface display outside of the graphical diagram.

Abstract: Methods, computer-readable media, software, and apparatuses may determine, for a geographic region and based on geolocation data, a plurality of sub-regions, where each sub-region of the plurality of sub-regions may include real properties with a shared profile. The system may associate, with each sub-region, a collection of coordinate pairs, where each coordinate pair comprises a latitude and a longitude, and the collection describes a boundary of a geometric shape corresponding to the sub-region. The system may associate, with the geographic region, geometric shapes corresponding to the plurality of sub-regions. The system may associate, with each geometric shape, a rating factor for the real properties located within the sub-region corresponding to the geometric shape. The system may store the geometric shapes and rating factors, and may generate, based on the rating factor and for the real properties located within the sub-region, an output, and provide the generated output.

Abstract: Methods and apparatus for planning and/or carrying out a total knee replacement surgical procedure on a knee of a leg of a patient are described. Anatomical data for the leg of the patient is obtained, which allows the femoral mechanical axis, the tibial mechanical axis, and the joint line of the knee to be determined. A planned proximal tibial cut angle and a planned distal femoral cut angle are determined. A total knee replacement procedure is carried out on the knee of the patient such that a distal femoral cut is made using the planned distal femoral cut angle and a proximal tibial cut is made using the planned proximal tibial cut angle.

Abstract: A quality assurance method for a radiotherapy device is disclosed. The method comprises disposing a phantom on a patient couch of the radiotherapy device, moving the patient couch to simulate motion of a subject, determining a measured value associated with the phantom, and comparing the measured value to an expected value. A radiotherapy device is also disclosed, the radiotherapy device comprising a radiation source configured to apply a radiation beam, a patient couch, a phantom disposable on the patient couch, and a controller communicatively coupled to the patient couch. A computer-readable medium storing instructions is also disclosed. A phantom for a radiotherapy device is also disclosed.