Abstract: The technology relates in part to compositions comprising modified caspase-9 polypeptides, compositions comprising nucleic acids coding for modified caspase-9 polypeptides, chimeric modified caspase-9 polypeptides, and methods of use thereof, including methods for cell therapy. Methods for cell therapy include modifying transfused cells to express an inducible modified caspase-9 protein, with reduced basal activity in the absence of the inducer.

Abstract: In some embodiments, a mobile device includes an interface configured to scan information from a communication tag associated with an asset, a memory operable to store the information, and a processor communicatively coupled to the memory. The information comprises a header describing the information, business application data, and asset identification data uniquely identifying the asset. The processor is configured to extract the business application data from the information scanned from the communication tag and extract the asset identification data from the information scanned from the communication tag.

Abstract: The present invention is directed to a composition and method which to treat diseases and to enhance a regulated immune response. More particularly, the present invention is drawn to compositions that are based on dendritic cells modified to express an inducible form of a co-stimulatory polypeptide.

Abstract: A method and system for transferring between combustion modes in a gas turbine engine is provided. A processor generates data representative of an initial set of splits for providing at least one of fuel and air to at least one combustor in the gas turbine engine. A gas turbine engine model module generates data representative of at least one engine operating condition. A first split calculation module generates data representative of at least one set of active control splits to control the engine in a first combustion mode, using as an input the initial split data. A second split calculation module generates data representative of at least one set of passive control splits to control the engine in at least a second combustion mode. Transfer between combustion modes may be accomplished via use of at least one of the active control splits and the passive control splits.

Abstract: The present invention relates to metrological rotary devices, such as anemometers and the like. Specifically, the present invention relates to a mechanical coupling for the same, whereby an anemometer cup-rotor or like device, can be replaced without the use of a tool. The present invention seeks to provide a coupling device which makes a mechanical coupling between a first and a second member such that the locking together and release action is positive, without likelihood of failure, and can be conducted simply and quickly without the use of a tool. Further objects of the invention are to provide couplings in which a positive axial and rotational location of shaft as first member and mating bore in a second member are obtained which do not cause damage to either of the sliding surfaces when excessive force is applied, and which are capable of transmitting a torque, such couplings being suitable for attaching a rotor to an anemometer.

Abstract: A method of augmenting power output by a gas turbine engine includes channeling fuel into the gas turbine engine at a predetermined fuel flow rate to generate a first power output. Steam is then injected into the gas turbine engine at a first steam flow rate, and a firing temperature bias is determined based at least on the first steam flow rate. The predetermined fuel flow rate is then adjusted based on the determined firing temperature bias such that the gas turbine engine generates a second power output greater than the first power output.

Abstract: A system is provided that includes a memory storing a turbomachinery degradation model configured to model degradation of a turbomachinery over time. The system also includes a controller communicatively coupled to the memory and configured to control the turbomachinery based on a feedback signal and the turbomachinery degradation model. Moreover, the turbomachinery degradation model is configured to use a target power to derive a control parameter by estimating a modeled power of the turbomachinery, and the controller is configured to use the control parameter to control the turbomachinery.

Abstract: The present invention is directed to a composition and method which to treat diseases and to enhance a regulated immune response. More particularly, the present invention is drawn to compositions that are based on dendritic cells modified to express an inducible form of a co-stimulatory polypeptide.

Abstract: A wireless apparatus utilizes a wireless transceiver, in communication with a processor, to transmit and receive messages via a wireless network. The wireless transceiver may receive a schedule definition for devices affiliated with a node of the wireless network. The processor may determine, from the received schedule definition, one or more time periods allocated to the wireless apparatus. The wireless transceiver may communicate with the wireless network in accordance with at least one of the one or more time periods.

Abstract: Embodiments of the disclosure relate to systems and methods for controlling a gas turbine. In one embodiment, a method can be provided. Measurement data associated with the operation of a gas turbine may be received to determine if the current operating state of the gas turbine is associated with a predefined risk. Thereafter, the measurement data and one or more model operating parameters for operation of the inlet bleed heat system that minimizes the risk may be identified in order to generate one or more control signals operable to adjust the operation of the inlet bleed heat system for the gas turbine to adjust the one or more model operating parameters.

Abstract: A system for conserving energy in a multi-node network (110) includes nodes (205) configured to organize themselves into tiers (305, 310,315). The nodes (205) are further configured to produce a transmit/receive schedule at a first tier (310) in the network (110) and control the powering-on and powering-off of transmitters and receivers in nodes (205) in a tier adjacent (315) to the first tier (310) according to the transmit/receive schedule.

Abstract: Methods, devices and compositions for diagnosing, predicting and monitoring a urinary tract infection in a subject are described. The detection, prediction and monitoring of a urinary tract infection in a subject by detection of HD5 in the urine of a subject is described.

Abstract: The technology relates generally to the field of immunology and relates in part to compositions and methods for controlling the proliferation of T cells, for example, therapeutic T cells. The methods further relate to compositions and methods for inducing an immune response in a subject.

Abstract: Provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing pattern recognition receptor activity, and CD40 activity. Also provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing CD40 activity without prostaglandin E2. Also provided are methods for activating an antigen-presenting cell and eliciting an immune response by inducing an inducible chimeric molecule comprising a region of a pattern recognition receptor or an adaptor thereof.

Abstract: The technology relates in part to compositions comprising modified Caspase-9 polypeptides, compositions comprising nucleic acids coding for modified Caspase-9 polypeptides, chimeric modified Caspase-9 polypeptides, and methods of use thereof, including methods for cell therapy. Methods for cell therapy include modifying transfused cells to express an inducible modified Caspase-9 protein, with reduced basal activity in the absence of the inducer.

Abstract: A system is provided that includes a memory storing a turbomachinery degradation model configured to model degradation of a turbomachinery over time. The system also includes a controller communicatively coupled to the memory and configured to control the turbomachinery based on a feedback signal and the turbomachinery degradation model. Moreover, the turbomachinery degradation model is configured to use a target power to derive a control parameter by estimating a modeled power of the turbomachinery, and the controller is configured to use the control parameter to control the turbomachinery.

Abstract: Solid-oxide fuel cells include an electrolyte and an anode electrically coupled to a first surface of the electrolyte. A cathode is provided, which is electrically coupled to a second surface of the electrolyte. The cathode includes a porous backbone having a porosity in a range from about 20% to about 70%. The porous backbone contains a mixed ionic-electronic conductor (MIEC) of a first material infiltrated with an oxygen-reducing catalyst of a second material different from the first material.

Abstract: The present invention is directed to a composition and method which to treat diseases and to enhance a regulated immune response. More particularly, the present invention is drawn to compositions that are based on dendritic cells modified to express an inducible form of a co-stimulatory polypeptide.

Abstract: A system includes a controller configured to control one or more parameters of a gas turbine engine based on a feedback and a predicted lifespan of one or more components of the gas turbine engine to substantially maintain at least one of power output or heat rate above a threshold level in response to degradation or fouling of the gas turbine engine.

Abstract: An extension ladder stabilizer includes a ladder rung engagement rod having threads along at least a portion of its length and configured to be disposed in and project from each end of a hollow tubular rung of an extension ladder, a pair of internal supports having a substantially gear shaped hole in each, a pair of external supports having a substantially gear shaped boss with a through hole on a first face and an anchor channel on a second face opposite the first face on each, and a pair of ground engagement members. In a ladder stabilizing configuration, the extension ladder stabilizer is installed on a ladder and the ground engagement members are passed through the anchor channels and into the ground to secure the ladder from side slipping, kicking back, and kicking over when in use.