Abstract: A gaseous fuel mixer assembly for an engine includes a mixer housing forming gas delivery openings, and positioned to extend across a flow path formed by an intake conduit for the engine. A spool valve is within a central bore in the mixer housing and includes gas distribution openings selectively connectable to the gas delivery openings by moving the spool valve within the mixer housing using a piezoelectric actuator coupled with the spool valve by way of a pivot arm. Sealing lands of the spool valve are in an alternating arrangement with the gas distribution openings, such that at the closed position the sealing lands block the gas distribution openings from the gas delivery openings, and at the open position the respective openings are fluidly connected.

Abstract: A cap for a container includes an annular tamper evident band with a generally rigid cylindrical frame having an upper ring and a plurality of ribs extending axially from the ring and spaced circumferentially apart about the ring. A plurality of retainer elements are supported by the frame, each retainer element connected at circumferentially opposed ends by resiliently flexible webs to adjacent ones of the ribs. The retainer elements are biased to a radially contracted position, in which the retainer elements protrude inwardly to engage an underside surface of a neck flange of the container. The retainer elements are movable to a radially expanded position in which the retainer elements can be advanced axially past the neck flange when installing the cap onto the container for the first time.

Abstract: A gaseous fuel mixer assembly for an engine includes a mixer housing forming gas delivery openings, and positioned to extend across a flow path formed by an intake conduit for the engine. A spool valve is within a central bore in the mixer housing and includes gas distribution openings selectively connectable to the gas delivery openings by moving the spool valve within the mixer housing using a piezoelectric actuator coupled with the spool valve by way of a pivot arm. Sealing lands of the spool valve are in an alternating arrangement with the gas distribution openings, such that at the closed position the sealing lands block the gas distribution openings from the gas delivery openings, and at the open position the respective openings are fluidly connected.

Abstract: Provided herein are primers and primer systems having improved specificity and kinetics over existing primers, and methods of use thereof.

Abstract: A method, system, and computer program product for detecting a network application security question is provided. The method includes receiving permission to access social media sources of a user. The social media sources and Internet based sources of the user are monitored in response to receiving the permission and associated data is generated and stored. A request for access to a secure account of the user is received and a list of security questions is presented to the user. The list of security questions is analyzed with respect to the data and each security question is ranked. An answer to a question of the list is received and analyzed and security attributes of the answer with respect to a potential malicious attempt to provide a predicted answer to for access to secure account are determined. A resulting security process with respect to enabling access to the secure account is executed.

Abstract: The present disclosure describes the thermodynamic design and concentrations necessary to design probe compositions with desired optimal specificity that enable enrichment, detection, quantitation, purification, imaging, and amplification of rare-allele-bearing species of nucleic acids (prevalence <1%) in a large stoichiometric excess of a dominant-allele-bearing species (wildtype). Being an enzyme-free and homogeneous nucleic acid enrichment composition, this technology is broadly compatible with nearly all nucleic acid-based biotechnology, including plate reader and fluorimeter readout of nucleic acids, microarrays, PCR and other enzymatic amplification reactions, fluorescence barcoding, nanoparticle-based purification and quantitation, and in situ hybridization imaging technologies.

Abstract: A method, computer system, and computer program product for protecting user data while performing third-party account registration. The method may include receiving, from a third party, a request for personal data of a user. The method may request the user to authenticate the request for personal data. In response to receiving from the user the authentication, the method may include providing the third party the personal data of the user. A portion of the personal data of the user that is provided to the third party may be altered and may be mapped to the user. The method may store identifying information about the third party. The method may also include receiving, from the user, a parameter respecting use of the portion of the personal data that is altered. The parameter may limit the third party from obtaining information from the portion of the personal data that is altered.

Abstract: A method, system, and computer program product for detecting a network application security question is provided. The method includes receiving permission to access social media sources of a user. The social media sources and Internet based sources of the user are monitored in response to receiving the permission and associated data is generated and stored. A request for access to a secure account of the user is received and a list of security questions is presented to the user. The list of security questions is analyzed with respect to the data and each security question is ranked. An answer to a question of the list is received and analyzed and security attributes of the answer with respect to a potential malicious attempt to provide a predicted answer to for access to secure account are determined. A resulting security process with respect to enabling access to the secure account is executed.

Abstract: Transaction information management is provided. A request for a transaction identifier is received from a first entity to perform a transaction with a user. Transaction information for the transaction determined with the transaction information including authorized entities and sets of personal information of the user available to each of the authorized entities. The transaction information is stored. The transaction identifier linked to the transaction is generated. The transaction identifier is provided to the first entity.

Abstract: The present disclosure describes the thermodynamic design and concentrations necessary to design probe compositions with desired optimal specificity that enable enrichment, detection, quantitation, purification, imaging, and amplification of rare-allele-bearing species of nucleic acids (prevalence <1%) in a large stoichiometric excess of a dominant-allele-bearing species (wildtype). Being an enzyme-free and homogeneous nucleic acid enrichment composition, this technology is broadly compatible with nearly all nucleic acid-based biotechnology, including plate reader and fluorimeter readout of nucleic acids, microarrays, PCR and other enzymatic amplification reactions, fluorescence barcoding, nanoparticle-based purification and quantitation, and in situ hybridization imaging technologies.

Abstract: Operating an internal combustion engine system includes advancing a prechamber piston in a fuel delivery igniter to push a main charge of fuel from a prechamber into a cylinder, and advancing the prechamber piston to compression-ignite a pilot charge within the prechamber. Combustion gases of the pilot charge are conveyed into the cylinder to ignite the main charge. Operation of the engine system provides sparkless gaseous fuel ignition.

Abstract: An ignition system for a gaseous fuel engine includes an igniter and an actuator structured to apply an actuating force to a piston within the igniter, to autoignite an ignition charge of fuel and air within the igniter. A housing of the igniter includes a gas orifice having a flow area that is increased between a combustion pre-chamber in the igniter and a main combustion chamber in the engine, to limit velocity of outgoing combustion gases to below a threshold velocity for engine mis-fire.

Abstract: Compositions and methods for highly specific nucleic acid probes and primers are provided. The probe system comprises a complement strand and a protector stand that form a partially double-stranded probe. The reaction standard free energy of hybridization between the probe and target nucleic acid as determined by Expression 1 (?G°rxn=?G°t-TC??G°nh-PC+(?G°v-TC??G°h-PC)) is from about ?4 kcal/mol to about +4 kcal/mol. Alternatively, the reaction standard free energy of hybridization between the probe and target nucleic acid is determined by Expression 1 to be within 5 kcal/mol of the standard free energy as determined by Expression 2 (?R?ln(([P]0?[C]0)/[C]0)]), where the [P]0 term of Expression 2 equals the concentration of the protector strand and the [C]0 term of Expression 2 equals the concentration of the complement strand. In addition, a method for on-the-fly fine tuning of a reaction using the present probe is provided.

Abstract: Described are techniques for an access management protocol including a method comprising associating a granted permission set and a constrained permission set to a user profile in an access management system. Respective granted permissions in the granted permission set authorize the user profile to perform the respective granted permissions, and respective constrained permissions in the constrained permission set preclude the user profile from performing the respective constrained permissions. The method further comprises receiving a permission-based request at the access management system and from the user profile and determining that the permission-based request is associated with a permission that is included in both the granted permission set and the constrained permission set. The method further comprises rejecting the permission-based request.

Abstract: This invention describes a method of controlling the hybridization yield of nucleic acid probes by adjusting the relative concentrations of auxiliary oligonucleotides to the probes and the targets. The auxiliary oligonucleotide is partially or fully complementary to either the probe or the target, and is released upon hybridization of the probe to the target.

Abstract: Provided herein are methods for encoding information in DNA molecules in a way that allows rapid and permanent erasure of information. As such, methods of erasing such information are also provided. Also provided are compositions that so encode information.

Abstract: Provided herein are reagents and methods for simultaneously enriching many potential rare genetic variants at different genetic loci. The rare variants enriched can include single nucleotide polymorphisms (SNPs), single nucleotide variants, or small insertions and deletions. Embodiments of the invention include procedures for integration with downstream next generation sequencing (NGS) analysis. Embodiments of the invention include analysis of nonpathogenic SNPs for the determination of cell identity and detection of cell contamination using qPCR or NGS.

Abstract: Compositions and methods for highly specific nucleic acid probes and primers are provided. The probe system comprises a complement strand and a protector stand that form a partially double-stranded probe. The reaction standard free energy of hybridization between the probe and target nucleic acid as determined by Expression 1 (?G°rxn=?G°t-TC??G°nh-PC+(?G°v-TC??G°h-PC)) is from about ?4 kcal/mol to about +4 kcal/mol. Alternatively, the reaction standard free energy of hybridization between the probe and target nucleic acid is determined by Expression 1 to be within 5 kcal/mol of the standard free energy as determined by Expression 2 (?R? ln(([P]0?[C]0)/[C]0)]), where the [P]0 term of Expression 2 equals the concentration of the protector strand and the [C]0 term of Expression 2 equals the concentration of the complement strand. In addition, a method for on-the-fly fine tuning of a reaction using the present probe is provided.

Abstract: Access is controlled to managed resources in a stateless web server architecture including a stateless web server computing platform; a resource locator map portion of the stateless web server computing platform providing a unique resource locator code representing each managed resource in a stateless web server architecture, wherein the managed resource is assigned to a plurality of application program components; a set of servlet filters disposed in a portion of the stateless web server computing platform, each servlet filter associated with one of the application program components; a resource locator matcher portion of the stateless web server computing platform, responsive to a user request to a unique resource locator, matching a pattern in the user request to one or more of the application program components using a corresponding servlet filter; and a request dispatcher portion of the stateless web server computing platform sending the user request to the matched application program component, wherein

Abstract: A method, computer system, and computer program product for protecting user data while performing third-party account registration. The method may include receiving, from a third party, a request for personal data of a user. The method may request the user to authenticate the request for personal data. In response to receiving from the user the authentication, the method may include providing the third party the personal data of the user. A portion of the personal data of the user that is provided to the third party may be altered and may be mapped to the user. The method may store identifying information about the third party. The method may also include receiving, from the user, a parameter respecting use of the portion of the personal data that is altered. The parameter may limit the third party from obtaining information from the portion of the personal data that is altered.