Abstract: Provided herein are compositions and methods for formation of amplicons having a chimeric sequence, partially derived from a target nucleic acid and partially derived from a rationally designed oligonucleotide. The provided compositions provide for high-yield, induced template switching between the target nucleic acid and the rationally designed oligonucleotide as the template during polymerase extension, achieving inheritance of information from both within only one cycle.

Abstract: Hierarchical virtualization creates a child guest partition that shares a hypervisor with a parent guest partition. A hypervisor receives a request, from a first guest partition that operates at the hypervisor, to create a second guest partition as a child of the first guest partition. The hypervisor identifies a configuration specification for the second guest partition, which includes (1) an identification of a memory portion, which is allocated to the first guest partition, that is to be mapped into the second guest partition; and (2) a configuration of a virtual processor that is to be utilized by the second guest partition. The hypervisor creates the second guest partition based on the configuration specification.

Abstract: An electrical connector comprises an outer housing, an insulating housing installed on the outer housing, a pair of terminal assemblies, and a shielding member. The terminal assemblies are installed in the insulating housing and are spaced apart from each other in a first direction to define an insertion space therebetween adapted to receive a connection terminal of a mating connector. Each terminal assembly includes a plurality of conductive terminals arranged in rows in a second direction perpendicular to the first direction. The plurality of conductive terminals of each terminal assembly include a signal terminal and a ground terminal. The shielding member is positioned at least partially between the two terminal assemblies in the first direction and includes a contact arm in electrical contact with the ground terminal.

Abstract: Systems and devices for cooling and dispensing a beverage fluid are disclosed herein. One beverage dispensing system includes a beverage tower comprising a tower body, a shank, and a faucet. In some implementations, a coolant line is routed proximal to a beverage supply line through the tower body, through the shank, and into the faucet. In these and other implementations, the faucet includes a removable nozzle having a supplemental portion of the coolant line. In these and still other implementations, the faucet include a removable nozzle having a second coolant line. The coolant line and the second coolant line are configured to transport a coolant medium proximal to a beverage fluid in the beverage supply line to maintain or adjust the temperature of the beverage fluid. Many other features are described herein.

Abstract: Systems and methods for incident response using artificial intelligence for information technology operations are disclosed. In one embodiment, a method may include an incident response computer program executed by an electronic device: (1) receiving an incident ticket for an incident involving a computer product or a computer system within an organization from a service management platform for the computer product or the computer system; (2) providing incident information from the incident ticket to a trained incident response machine learning engine, wherein the trained incident response machine learning engine is trained to predict a solution for the incident based on historical incident data; (3) receiving, from the trained incident response machine learning engine, a predicted solution for the incident; and (4) providing the predicted solution to the service management platform. The service management platform provides the predicted solution to the computer product or the computer system.

Abstract: A processor-implemented method includes generating, by a scheduling model, a group of schedules from a computation graph associated with a task, each node on the computation graph being associated with an operation of an artificial neural network, each schedule of the group of schedules associating each node of the computation graph with a processor of a group of processors of a hardware device. The processor-implemented method also includes testing one or more schedules of the group of schedules on the hardware device or a model of the hardware device. The processor-implemented method further includes selecting a schedule of the one or more schedules based on testing the one or more schedules, the selected schedule satisfying a selection condition.

Abstract: This disclosure describes, in part, systems for enabling facilities to implement techniques to determine when users are in possession of items when located within and/or exiting the facilities. For instance, a system may use one or more sensors to determine locations of a user that navigated through a facility. Additionally, the system may use one or more sensors to determine locations of an item while the item was located within the facility. The system may then determine a probability that the user was in possession of the item when in the facility and/or when exiting the facility based at least in part on the locations of the user and the locations of the item. If the system determines that the user was in possession of the item when exiting the facility, the system may charge a payment instrument of the user for a price of the item.

Abstract: The present disclosure relates to implantable constructs and related compositions comprising a plurality of cells producing antigens and/or immune effector molecules.

Abstract: Isolating resources of a virtual machine (VM) guest from a host operating system. A computer system receives an acceptance request from a guest partition corresponding to an isolated VM. The acceptance request identifies a guest memory page that is mapped into a guest physical address space of the guest partition, and a memory page visibility class. The computer system determines whether a physical memory page that is mapped to the guest memory page meets the memory page visibility class. The computer system sets a page acceptance indication for the guest memory page from an unaccepted state to an accepted state based on the physical memory page meeting the memory page visibility class.

Abstract: Provided is a light converter and its method of manufacture. A light conversion layer containing light conversion particles in a binding material is provided for generating emission light from excitation light incident on the light conversion layer. A planarization layer is disposed on a surface of the light conversion layer. At least one optical coating is part of or on a surface of the planarization layer that is relatively smooth in comparison with the surface of the light conversion layer.

Abstract: Disclosed are systems and methods of accessing content items stored at a content management system by a mobile device, when the mobile device is not communicatively coupled to the content management system. The content management system can receive an indication to mark a content item (e.g., folder and the content items associated with the folder) as available to a mobile device when the mobile device is offline. The content management system can mark the content item, and any content items associated with the content item, for offline access by the mobile device and determine a synchronization schedule for the content item(s). The content management system can then initially send to the mobile device, the marked content item(s) in accordance with the synchronization schedule. While offline, the mobile device can make changes to the marked content items. The changes can be synchronized between the mobile device and content management system when the mobile device is online.

Abstract: Provided herein are non-extensible oligonucleotides for suppressing enzymatic extension through rationally designed secondary structures at the 3? end. Embodiments of the invention include procedures for integration with real-time polymerase chain reaction, blocker displacement amplification in quantitative PCR, next generation sequencing (NGS), and long-read sequencing.

Abstract: A solar tracking system includes a beam including a pair of legs disposed in spaced relation to one another and extending between respective first and second end portions, a web extending between the first end portion of each of the pair of legs, the web including a V-shaped notch defined therein, and a pair of return flanges defining a respective first end portion disposed on respective second end portions of the pair of legs, the pair of return flanges extending from each respective leg of the pair of legs and terminating at a second end portion defining a gap between the second end portions of the pair of return flanges, and a bearing housing assembly selectively couplable to a portion of the beam.

Abstract: A light converter and method of manufacture is provided. A light conversion layer (301), comprising light conversion particles (301a) in a binding material (301b) is provided for generating emission light from excitation light incident on the light conversion layer (301). A planarization layer (304) is on a surface of the light conversion layer (301) and at least one optical coating (305) is part of or on a surface of the planarization layer (304) that is relatively smooth in comparison with the surface of the light conversion layer (301).

Abstract: The present disclosure relates to implantable constructs (encapsulated cells) designed to deliver antigenic therapeutic reagents, such as IL-2.

Abstract: A desulfurization gas process includes water vapor, CO2 and SOx (x=2 and/or 3). In a treatment unit, the gas contacts a cooled alkaline aqueous solution having a temperature lower than an initial gas temperature, water and a carbonate of an alkali metal, to cool the gas, condense some water vapor and absorb SOx in the carbonate-containing solution, produce an SOx-depleted gas and an acidic aqueous solution including sulfate and/or sulfite ions. The SOx-depleted gas and a portion of the acidic aqueous solution can then be withdrawn from the treatment unit. Carbonate of the alkali metal can be added to remaining acidic aqueous solution to obtain a made-up alkaline aqueous solution. This solution can be cooled and reused as the cooled alkaline aqueous solution. An SOx absorbent solution includes a bleed stream from a CO2-capture process, sodium or potassium carbonate, and an acidic aqueous solution obtained from desulfurization.

Abstract: A connector assembly comprises a circuit board having a front side and a back side, and two first connectors mounted side by side on the front side of the circuit board. A cable includes a plurality of wires divided into two groups, with each of the groups of wires being electrically connected on one end to a respective one of the first connectors via the circuit board.

Abstract: A connector assembly comprises a circuit board having a front side and a back side, with a connector installed on the front side of the circuit board. A plurality of first welding pads are formed on the front side of the circuit board, and a plurality of second welding pads are formed on the back side of the circuit board. A plurality of wires are connected to the circuit board, with a first portion thereof connected to the first welding pads and a second portion thereof connected to the second welding pads. Each of the plurality of wires extend away from the circuit board from above the front side of the circuit board.

Abstract: Provided herein are reagents and methods for comprehensively enriching potential variants within targeted regions, named Amplicon Comprehensive Enrichment (ACE). The sequence variants enriched can include single nucleotide polymorphisms (SNPs), single nucleotide variants, or small insertions and deletions. Embodiments include procedures for integration with real-time polymerase chain reaction, next generation sequencing (NGS), and long-read sequencing.

Abstract: The present invention relates to novel therapeutic agents against hepatitis B virus (HBV) infection, particularly inhibitors of viral covalently closed circular DNA (cccDNA) which is the key barrier for HBV cure. Accordingly, the invention provides the pyrrolo[2,3-b]pyrazine compounds of formula (I), as described and defined herein, for use in the treatment of HBV infection. The compounds provided herein are highly potent against HBV infection and enable an improved therapy, particularly of chronic HBV infection and HBV rebound. The present invention further relates to a novel screening assay for the identification of therapeutic agents against HBV infection, particularly cccDNA inhibitors, which is performed in hepatocyte-like cells that recapitulate the complete HBV life cycle following infection with patient-derived HBV.