Abstract: A protected direct-drive depletion-mode (D-mode) GaN semiconductor half-bridge power module is disclosed. Applications include high power inverter applications, such as 100kW to 200kW electric vehicle traction inverters, and other motor drives. The high-side switch is a normally-on D-mode GaN semiconductor power switch Q1 in series with a normally-off LV Si MOSFET power switch M1 and the low-side switch is a normally on D-mode GaN semiconductor power switch Q2. The gates of both Q1 and Q2 are directly driven. M1 in series with Q1 provides a high-side switch which is a normally-off device for start-up and fail-safe protection. M1 may also be used for current sensing and overcurrent protection. For example, a control circuit determines an operational mode of M1 responsive to a UVLO signal and a voltage sense signal indicative of an overcurrent event. Examples of single phase and three-phase half-bridge modules and driver circuits are described.

Abstract: Bitrate-adaptive segmentation is performed for transcoding a video stream uploaded to an online video platform for hosting and later playback to platform users. The video stream is segmented into chunks based on prediction-based bit costs determined for frames of the video stream rather than based on scene changes detected within the video stream. The bitrate-adaptive segmentation includes determining inter-prediction bit costs and intra-prediction bit costs for frames of the video stream based on information indicated within a pass log based on a first pass encoding of the video stream, determining chunk boundaries for segmenting the video stream into a chunk based on the inter-prediction bit costs and the intra-prediction bit costs for the frames, and transcoding the chunk to produce a transcoded video stream.

Abstract: The present disclosure relates to compositions and methods for modulating gene expression and in particular to compositions and methods for increasing expression of Klotho. For example, the present disclosure provides methods for increasing expression of a Klotho gene in a human cell comprising introducing into the cell a CRISPR enzyme and a guide RNA comprising a guide sequence that is substantially complementary to a target sequence within or near the Klotho gene, wherein the guide RNA or the CRISPR enzyme associates with a transcriptional activation domain.

Abstract: Bitrate-adaptive segmentation is performed for transcoding a video stream uploaded to an online video platform for hosting and later playback to platform users. The video stream is segmented into chunks based on prediction-based bit costs determined for frames of the video stream rather than based on scene changes detected within the video stream. The bitrate-adaptive segmentation includes determining inter-prediction bit costs and intra-prediction bit costs for frames of the video stream based on information indicated within a pass log based on a first pass encoding of the video stream, determining chunk boundaries for segmenting the video stream into a chunk based on the inter-prediction bit costs and the intra-prediction bit costs for the frames, and transcoding the chunk to produce a transcoded video stream.

Abstract: A controller and a method for controlling motion of a vehicle is provided. The method comprises acquiring motion information including a current state of the vehicle and a desired state of the vehicle, determining a combination of a steering angle of the wheels and motor forces for moving the vehicle from the current state into the desired state by using a first model of the motion of the vehicle and a second model of the motion of the chassis of the vehicle, determining a cost function of the motion of the vehicle, optimizing the cost function of the motion of the vehicle to compute a command signal for controlling the steering wheel and the plurality of electric motors, and controlling the steering angle of the wheels and the motor forces based on the command signal.

Abstract: Low inductance power modules for ultra-fast wide-bandgap semiconductor power switching devices are disclosed. Conductive tracks define power buses for a switching topology, e.g. comprising GaN E-HEMTs, with power terminals extending from the power buses through the housing to provide a heatsink-to-busbar distance which meets creepage and clearance requirements. Low-profile, low-inductance terminals for gate and source-sense connections extend from contact areas located adjacent each power switching device to provide for a low inductance gate drive loop, for high di/dt switching. The gate driver board is mounted on the low-profile terminals, inside or outside of the housing, with decoupling capacitors provided on the driver board. For paralleled switches, additional terminals, which are referred to as dynamic performance pins, are provided to the power buses.

Abstract: An apparatus for controlling a cylinder by a microfluidic stream includes a microtube, a first laser-driven photoacoustic microfluid pump (LDMP), and a fiber optic element. The microtube includes a fluid and a cylinder. The fiber optic element includes a first end and a second end. The first end is disposed on the first LDMP and the second end is disposed in a first end portion of the microtube. The first LDMP is configured to generate a directional fluidic jet from the fluid and to push the cylinder in a direction away from the second end of the fiber optic element.

Abstract: An AC/DC Switching Mode Power Supply (SMPS) comprises a PFC stage, an isolated LLC DC/DC converter stage, and a control circuit that provides feedback/control signals to PFC and LLC controllers, to enable a plurality of operating modes, dependent on a sensed peak AC input voltage and required output voltage Vo. The PFC provides a first DC bus voltage Vdc (e.g. 200V) for low line AC input and a second DC bus voltage (e.g. 400V) for high line or universal AC input. A multi-mode LLC converter is operable in a half-bridge mode or a full-bridge mode. For low line AC input, output voltage Vo, and PFC output Vdc, the LLC operates in full-bridge mode; for high line input, output voltage Vo and PFC output 2×Vdc, the LLC operates in half-bridge mode; for universal AC input, output voltage 2×Vo, and PFC output 2×Vdc, the LLC operates in full-bridge mode.

Abstract: A light emission module includes a laser source, a beam steering element and a scanning-angle expanding lens set. The laser source is used for emitting a laser beam. The beam steering element is used for receiving the laser beam and splitting the laser beam into at least two laser beams. The scanning-angle expanding lens set, adjacent to the beam steering element, is configured to receive and integrate the at least two laser beams, and to control a spanning angle and a scanning angle between the at least two laser beams on a scanned object. The spanning angle is a visual angle of a vertical scan direction of the scanned object, and the scanning angle is another visual angle of a horizontal scan direction of the scanned object. In addition, a light emission module and a light scanning method are also provided.

Abstract: The present invention relates to a device (10) for supplying a mist of liquid (F). The device (10) is used in combination with a container (20) with an opening (200) for containing the liquid (F).

Abstract: A controller and a method for controlling motion of a vehicle is provided. The method comprises acquiring motion information including a current state of the vehicle and a desired state of the vehicle, determining a combination of a steering angle of the wheels and motor forces for moving the vehicle from the current state into the desired state by using a first model of the motion of the vehicle and a second model of the motion of the chassis of the vehicle, determining a cost function of the motion of the vehicle, optimizing the cost function of the motion of the vehicle to compute a command signal for controlling the steering wheel and the plurality of electric motors, and controlling the steering angle of the wheels and the motor forces based on the command signal.

Abstract: An AC/DC Switching Mode Power Supply (SMPS) comprises a PFC stage, an isolated LLC DC/DC converter stage, and a control circuit that provides feedback/control signals to PFC and LLC controllers, to enable a plurality of operating modes, dependent on a sensed peak AC input voltage and required output voltage Vo. The PFC provides a first DC bus voltage Vdc (e.g. 200V) for low line AC input and a second DC bus voltage (e.g. 400V) for high line or universal AC input. A multi-mode LLC converter is operable in a half-bridge mode or a full-bridge mode. For low line AC input, output voltage Vo, and PFC output Vdc, the LLC operates in full-bridge mode; for high line input, output voltage Vo and PFC output 2×Vdc, the LLC operates in half-bridge mode; for universal AC input, output voltage 2×Vo, and PFC output 2×Vdc, the LLC operates in full-bridge mode.

Abstract: Provided herein are methods for the treatment and prevention of vascular lesions arising from RASA1 and/or EPHB4 mutations and associated with capillary malformation-arteriovenous malformation (CM-AVM).

Abstract: The present disclosure relates to compositions and methods for modulating gene expression and in particular to compositions and methods for increasing expression of Klotho. In certain examples, the present disclosure provides a method of increasing expression of a Klotho gene in a cell the method comprising administering to the cell a binding molecule that binds to an RNA transcript transcribed from a chromosomal region within or near the Klotho gene, wherein the RNA transcript does not encode a Klotho protein.

Abstract: A task-based learning using task-directed prediction network can be provided. Training data can be received. Contextual information associated with a task-based criterion can be received. A machine learning model can be trained using the training data. A loss function computed during training of the machine learning model integrates the task-based criterion, and minimizing the loss function during training iterations includes minimizing the task-based criterion.

Abstract: This application provides a live streaming processing method performed by an electronic device. The method includes: displaying a live streaming room, the live stream room having a host account, a host sub-account and multiple viewer accounts, the host sub-account being used for assisting the host account of the live streaming room in operation; receiving real-time live streaming data of the live streaming room, and displaying a live streaming content on a live streaming room page according to the real-time live streaming data, the real-time live streaming data collected from the host account and the viewer accounts; and displaying, in response to a live streaming room operation of the host sub-account, an operation result of the live streaming room operation of the host sub-account in the live streaming room, wherein the operation result of the live streaming room operation updates the live streaming content on the live streaming room page.