Abstract: A power supply processing device includes three electric control valve groups, a positive output terminal and a conversion control switch group. The conversion control switch group includes a selection switch group configured to selectively connect the current valve control components in each electric control valve group to the positive output terminal or the phase output terminal, and a connection switch group configured to connect or disconnect a current path between two electric control valve groups connected one another. In such a way, both AC experiments and DC experiments of high voltage and large capacity may be performed to the connectors without changing experimental site and experimental equipment, thereby effectively reducing the experimental cost.

Abstract: The present disclosure relates to compositions and methods for modulating gene expression and in particular to DNA binding proteins and their use for increasing expression of Klotho. In some examples, the present disclosure provides an isolated or recombinant DNA binding protein comprising or attached to a transcriptional activation domain wherein the DNA binding protein binds to a target sequence within or near a Klotho gene.

Abstract: Embedded die packaging for high voltage, high temperature operation of power semiconductor switching devices is disclosed, wherein a power semiconductor die is embedded in laminated body comprising a layer stack of a plurality of dielectric layers and electrically conductive layers, and wherein a first thermal pad on one side of the package and a second thermal pad on an opposite side of the package provides for dual-side cooling. Example embodiments of the dual-side cooled package may be based on a bottom-side cooled layup with a primary bottom-side thermal pad and a secondary top-side thermal pad, or a top-side cooled layup with primary top-side thermal pad and a secondary bottom side thermal pad, using layups with or without a leadframe. For example, the power semiconductor switching device comprises a GaN power transistor, such as a GaN HEMT rated for operation at ?100V or ?600V, for switching tens or hundreds of Amps.

Abstract: A protected direct-drive depletion-mode (D-mode) GaN semiconductor half-bridge power module is disclosed. Applications include high power inverter applications, such as 100kW to 200kW electric vehicle traction inverters, and other motor drives. The high-side switch is a normally-on D-mode GaN semiconductor power switch Q1 in series with a normally-off LV Si MOSFET power switch M1 and the low-side switch is a normally on D-mode GaN semiconductor power switch Q2. The gates of both Q1 and Q2 are directly driven. M1 in series with Q1 provides a high-side switch which is a normally-off device for start-up and fail-safe protection. M1 may also be used for current sensing and overcurrent protection. For example, a control circuit determines an operational mode of M1 responsive to a UVLO signal and a voltage sense signal indicative of an overcurrent event. Examples of single phase and three-phase half-bridge modules and driver circuits are described.

Abstract: Bitrate-adaptive segmentation is performed for transcoding a video stream uploaded to an online video platform for hosting and later playback to platform users. The video stream is segmented into chunks based on prediction-based bit costs determined for frames of the video stream rather than based on scene changes detected within the video stream. The bitrate-adaptive segmentation includes determining inter-prediction bit costs and intra-prediction bit costs for frames of the video stream based on information indicated within a pass log based on a first pass encoding of the video stream, determining chunk boundaries for segmenting the video stream into a chunk based on the inter-prediction bit costs and the intra-prediction bit costs for the frames, and transcoding the chunk to produce a transcoded video stream.

Abstract: The present disclosure relates to compositions and methods for modulating gene expression and in particular to compositions and methods for increasing expression of Klotho. For example, the present disclosure provides methods for increasing expression of a Klotho gene in a human cell comprising introducing into the cell a CRISPR enzyme and a guide RNA comprising a guide sequence that is substantially complementary to a target sequence within or near the Klotho gene, wherein the guide RNA or the CRISPR enzyme associates with a transcriptional activation domain.

Abstract: Bitrate-adaptive segmentation is performed for transcoding a video stream uploaded to an online video platform for hosting and later playback to platform users. The video stream is segmented into chunks based on prediction-based bit costs determined for frames of the video stream rather than based on scene changes detected within the video stream. The bitrate-adaptive segmentation includes determining inter-prediction bit costs and intra-prediction bit costs for frames of the video stream based on information indicated within a pass log based on a first pass encoding of the video stream, determining chunk boundaries for segmenting the video stream into a chunk based on the inter-prediction bit costs and the intra-prediction bit costs for the frames, and transcoding the chunk to produce a transcoded video stream.

Abstract: A controller and a method for controlling motion of a vehicle is provided. The method comprises acquiring motion information including a current state of the vehicle and a desired state of the vehicle, determining a combination of a steering angle of the wheels and motor forces for moving the vehicle from the current state into the desired state by using a first model of the motion of the vehicle and a second model of the motion of the chassis of the vehicle, determining a cost function of the motion of the vehicle, optimizing the cost function of the motion of the vehicle to compute a command signal for controlling the steering wheel and the plurality of electric motors, and controlling the steering angle of the wheels and the motor forces based on the command signal.

Abstract: Low inductance power modules for ultra-fast wide-bandgap semiconductor power switching devices are disclosed. Conductive tracks define power buses for a switching topology, e.g. comprising GaN E-HEMTs, with power terminals extending from the power buses through the housing to provide a heatsink-to-busbar distance which meets creepage and clearance requirements. Low-profile, low-inductance terminals for gate and source-sense connections extend from contact areas located adjacent each power switching device to provide for a low inductance gate drive loop, for high di/dt switching. The gate driver board is mounted on the low-profile terminals, inside or outside of the housing, with decoupling capacitors provided on the driver board. For paralleled switches, additional terminals, which are referred to as dynamic performance pins, are provided to the power buses.

Abstract: An apparatus for controlling a cylinder by a microfluidic stream includes a microtube, a first laser-driven photoacoustic microfluid pump (LDMP), and a fiber optic element. The microtube includes a fluid and a cylinder. The fiber optic element includes a first end and a second end. The first end is disposed on the first LDMP and the second end is disposed in a first end portion of the microtube. The first LDMP is configured to generate a directional fluidic jet from the fluid and to push the cylinder in a direction away from the second end of the fiber optic element.

Abstract: An AC/DC Switching Mode Power Supply (SMPS) comprises a PFC stage, an isolated LLC DC/DC converter stage, and a control circuit that provides feedback/control signals to PFC and LLC controllers, to enable a plurality of operating modes, dependent on a sensed peak AC input voltage and required output voltage Vo. The PFC provides a first DC bus voltage Vdc (e.g. 200V) for low line AC input and a second DC bus voltage (e.g. 400V) for high line or universal AC input. A multi-mode LLC converter is operable in a half-bridge mode or a full-bridge mode. For low line AC input, output voltage Vo, and PFC output Vdc, the LLC operates in full-bridge mode; for high line input, output voltage Vo and PFC output 2×Vdc, the LLC operates in half-bridge mode; for universal AC input, output voltage 2×Vo, and PFC output 2×Vdc, the LLC operates in full-bridge mode.

Abstract: A light emission module includes a laser source, a beam steering element and a scanning-angle expanding lens set. The laser source is used for emitting a laser beam. The beam steering element is used for receiving the laser beam and splitting the laser beam into at least two laser beams. The scanning-angle expanding lens set, adjacent to the beam steering element, is configured to receive and integrate the at least two laser beams, and to control a spanning angle and a scanning angle between the at least two laser beams on a scanned object. The spanning angle is a visual angle of a vertical scan direction of the scanned object, and the scanning angle is another visual angle of a horizontal scan direction of the scanned object. In addition, a light emission module and a light scanning method are also provided.

Abstract: The present invention relates to a device (10) for supplying a mist of liquid (F). The device (10) is used in combination with a container (20) with an opening (200) for containing the liquid (F).

Abstract: A controller and a method for controlling motion of a vehicle is provided. The method comprises acquiring motion information including a current state of the vehicle and a desired state of the vehicle, determining a combination of a steering angle of the wheels and motor forces for moving the vehicle from the current state into the desired state by using a first model of the motion of the vehicle and a second model of the motion of the chassis of the vehicle, determining a cost function of the motion of the vehicle, optimizing the cost function of the motion of the vehicle to compute a command signal for controlling the steering wheel and the plurality of electric motors, and controlling the steering angle of the wheels and the motor forces based on the command signal.

Abstract: An AC/DC Switching Mode Power Supply (SMPS) comprises a PFC stage, an isolated LLC DC/DC converter stage, and a control circuit that provides feedback/control signals to PFC and LLC controllers, to enable a plurality of operating modes, dependent on a sensed peak AC input voltage and required output voltage Vo. The PFC provides a first DC bus voltage Vdc (e.g. 200V) for low line AC input and a second DC bus voltage (e.g. 400V) for high line or universal AC input. A multi-mode LLC converter is operable in a half-bridge mode or a full-bridge mode. For low line AC input, output voltage Vo, and PFC output Vdc, the LLC operates in full-bridge mode; for high line input, output voltage Vo and PFC output 2×Vdc, the LLC operates in half-bridge mode; for universal AC input, output voltage 2×Vo, and PFC output 2×Vdc, the LLC operates in full-bridge mode.

Abstract: Provided herein are methods for the treatment and prevention of vascular lesions arising from RASA1 and/or EPHB4 mutations and associated with capillary malformation-arteriovenous malformation (CM-AVM).