Publication number: 20100004286
Abstract: Disclosed are isoindolinone derivatives, represented by Chemical Formula 1, having inhibitory activity against T-type calcium channels, pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition comprising the same as an active ingredient. wherein R1˜R6 are as defined in the specification.
Type:
Application
Filed:
October 23, 2008
Publication date:
January 7, 2010
Applicant:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventors:
Yong Seo CHO, Ae Nim PAE, Hyunah CHOO, Jae Kyun LEE, You Na OH, Hee Sup SHIN, Dong Jin KIM, Hoh Gyu HAHN, Kyung Il CHOI, Ghilsoo NAM, Kye Jung SHIN, Soon Bang KANG, Eun Joo ROH, Dong Yun SHIN, Seon Hee SEO, Hyewhon RHIM, Gyo Chang KEUM, Key-Sun KIM, Chan Seong CHEONG, Eunice Eun-Kyeong KIM, Cheolju LEE, Youngsoo KIM, Kee Hyun CHOI, Kee Dal NAM, Woong Seo PARK, Yong Koo KANG, Hye Jin CHUNG