Abstract: The disclosure relates to processes for reducing the amount of a compound of formula (I) or a salt or a solvate thereof present in a composition comprising compounds of formulae (I) and (II) or a salt or a solvate thereof.

Abstract: An on-vehicle system for assessing an operator's efficiency of a vehicle, include sensors, an audiovisual display device, a processor and a data storage. The sensors measure or detect conditions of components of the vehicle, and convert the detected conditions into analog or digital information. The data storage stores program instructions, the analog or digital information from the sensors, and other data. The program instructions, when executed by the processor, control the on-vehicle system to determine a state of the vehicle within a vehicle's environment based on the analog or digital information from the sensors, determine whether one or more of a predetermined set of behaviors has occurred based on the determined state of a vehicle, assess performance of the determined one or more of the predetermined set of behaviors, and present the operator, via the audiovisual display device, a feedback based on the assessment.

Abstract: Processes for preparing oxymorphone are provided. Said processes encompass a step which is a hydrogenation of an 14-hydroxymorphinone salt in the presence of trifluoroacetic acid and/or a glycol.

Abstract: A valvetrain includes a rocker arm assembly having an electromagnetic latch housed in a chamber formed by a rocker arm. The chamber may be a retrofit hydraulic chamber. A flux shifting bi-stable latch provides a sufficiently compact design. Isolation of the magnetic elements within the rocker arm chamber may provide protection from metal particles carried by oil in an operating environment for the rocker arm assembly. Wiring connections to the rocker arms may be made through spring posts on the rocker arms. Connection to the rocker arms may be made with springs that can endure the rapid motion induced by the rocker arms. A wiring harness for the rocker arms may attach to hydraulic lash adjusters of the rocker arm assemblies. The rocker arm assemblies and their wiring may be formed into a unitary module that facilitates installation.

Abstract: A strut fitting for a strut includes a fitting body having opposite ends and a length extending between the opposite ends. First and second opposite faces extend along the length of the body. Opposite sides are disposed between the first and second faces and extend along the length of the body. The first face and at least portions of the opposite sides adjacent the first face define a first cross-sectional shape of the fitting body that is generally dovetail-shaped. A catch is secured to and extends outward from the first face of the fitting body. The catch is resiliently deflectable relative to the fitting body.

Abstract: A system and method for cylinder deactivation in a multi-cylinder diesel engine comprises pumping air in to an intake manifold of the diesel engine using a turbocharger. Air is pumped in to the intake manifold using an intake air assisting device. And, fuel injection is selectively deactivated to at least one of the cylinders in the diesel engine. An intake valve and an exhaust valve is selectively deactivated for the at least one of the cylinders of the diesel engine.

Abstract: The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine.

Abstract: The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine.

Abstract: Systems and methods for transaction/file-based management of a plurality of processes associated with various jobs are provided. Through the management of discrete applications, a file distribution manager/scheduler orchestrates automated execution of different types of jobs. The processes executed for the various processes can vary based on job type, or other parameters.

Abstract: A switching rocker arm assembly constructed in accordance to one example of the present disclosure can include an outer arm, an inner arm, a pivot axle, a bearing axle, a first torsional bearing axle spring and a second torsional bearing axle spring. The outer arm can have a first outer side arm and a second outer side arm. The outer arm can further include first and second torsional spring mounts. The inner arm can be disposed between the first and second outer side arms. The pivot axle can support the inner and outer arm for relative pivotal movement therearound. The bearing axle can support a bearing. The first torsional bearing axle spring can be mounted around the first torsional spring mount and have a first end engaged to the bearing axle and a second end engaged to the outer arm. The first end extends inboard relative to the second end.

Abstract: The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine.

Abstract: Processes for preparing oxymorphone are provided. Said processes encompass a step which is a hydrogenation of an 14-hydroxymorphinone salt in the presence of trifluoroacetic acid and/or a glycol.

Abstract: Processes for preparing oxycodone are provided. Said processes encompass a step which is a hydrogenation of an 14-hydroxycodeinone salt in the presence of trifluoroacetic acid and/or a glycol.

Abstract: The present invention involves cases and overlays for a handheld electronic devices used for data entry. The case comprises a cover portion and an overlay portion having one or more actuatable keys for interacting with an enclosed electronic device without direct physical contact of the device by a user. Optionally the overlay portion includes one or more openings which allows a user to directly contact the enclosed device. Interchangeable overlays are also disclosed allowing for different combinations and configurations of keys and/or openings depending on the electronic device being used and the desired task being performed.

Abstract: The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine.

Abstract: An apparatus for measuring at least one of temperature and pressure within a cylinder of an internal combustion engine can include an engine valve and a sensor. The internal combustion engine can include a valvetrain having rocker arm assembly, a camshaft, a valve, and a hydraulic lash adjuster. The engine valve can have a valve head and a valve stem extending from the valve head in an axial direction. The valve head can have a valve face configured to be in pressure communication with an engine cylinder. The valve stem can have an outer surface with a cylindrical portion and a variably-shaped portion. The variably-shaped portion can define a target detectable by the sensor and the sensor can be installed adjacent to the target. Alternatively, the sensor can be positioned to detect a level of force at some point along the valvetrain.

Abstract: A method of measuring optical properties of a multi-mode optical fiber during processing of the fiber is described. The method includes: transmitting a light signal through one of the draw end of the multi-mode fiber and a test fiber section toward the other of the draw end and the test fiber section; and receiving a portion of the light signal at one of the draw end and the test fiber section. The method also includes obtaining optical data related to the received portion of the light signal; and analyzing the optical data to determine a property of the multi-mode fiber.

Abstract: The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine.

Abstract: The present disclosure provides processes for the N-dealkylation of tertiary amines and the use of transition metal catalysts to prepare tertiary N-allyl amine derivatives and secondary amine derivatives thereof. The tertiary amines can be alkaloids and, more particularly, the tertiary amines can be opioids. In specific embodiments, the present disclosure provides methods for use in processes for the synthesis of naloxone and naltrexone from oripavine.