Patents by Inventor Eiichi Nakano

Eiichi Nakano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110065153
    Abstract: The ability and speed with which a coryneform bacterium can produce L-lysine are improved when the coryneform bacterium contains an aspartokinase in which feedback inhibition by L-lysine and L-threonine is substantially desensitized. This is accomplished by successively enhancing the DNA coding for dihydrodipicolinate reductase, the DNA coding for dihydrodipicolinate synthase, the DNA coding for diaminopimelate decarboxylase, and the DNA coding for diaminopimelate dehydrogenase.
    Type: Application
    Filed: October 29, 2010
    Publication date: March 17, 2011
    Inventors: SEIKO OTSUNA, MASAKAZU SUGIMOTO, MASAKO IZUI, ATSUSHI HAYAKAWA, EIICHI NAKANO, MASAKI KOBAYASHI, YASUHIKO YOSHIHARA, TSUYOSHI NAKAMATSU
  • Patent number: 7846698
    Abstract: The L-lysine-producing ability and the L-lysine-producing speed are improved in a coryneform bacterium harboring an aspartokinase in which feedback inhibition by L-lysine and L-threonine is substantially desensitized, by successively enhancing DNA coding for a dihydrodipicolinate reductase, DNA coding for a dihydrodipicolinate synthase, DNA coding for a diaminopimelate decarboxylase, and DNA coding for a diaminopimelate dehydrogenase.
    Type: Grant
    Filed: August 23, 2002
    Date of Patent: December 7, 2010
    Assignee: Ajinomoto Co., Inc.
    Inventors: Seiko Otsuna, Masakazu Sugimoto, Masako Izui, Atsushi Hayakawa, Eiichi Nakano, Masaki Kobayashi, Yasuhiko Yoshihara, Tsuyoshi Nakamatsu
  • Publication number: 20030054506
    Abstract: The L-lysine-producing ability and the L-lysine-producing speed are improved in a coryneform bacterium harboring an aspartokinase in which feedback inhibition by L-lysine and L-threonine is substantially desensitized, by successively enhancing DNA coding for a dihydrodipicolinate reductase, DNA coding for a dihydrodipicolinate synthase, DNA coding for a diaminopimelate decarboxylase, and DNA coding for a diaminopimelate dehydrogenase.
    Type: Application
    Filed: August 23, 2002
    Publication date: March 20, 2003
    Applicant: AJINOMOTO CO. INC.
    Inventors: Seiko Otsuna, Masakazu Sugimoto, Masako Izui, Atsushi Hayakawa, Eiichi Nakano, Masaki Kobayashi, Yasuhiko Yoshihara, Tsuyoshi Nakamatsu
  • Patent number: 6521304
    Abstract: The present invention relates to luminescent playthings such as candles, table lights, pen lights, illumination, illuminating playthings for camp, illuminating playthings for night fishing, fish-gathering lamps, safety candles, neon lights, luminescent inks, luminescent pens, luminescent coatings or luminescent writing implements, in which a soft light of an indescribable tone of color not obtainable from flames of conventional candles is emitted via seawater, lake and marsh water, river water, ground water, tap water or mineral drinking water by utilizing 3 components of luciferin, luciferase and ATP or 4 components of these components plus a metal salt, out of components necessary for bioluminescence in fireflies.
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: February 18, 2003
    Assignee: Kikkoman Corporation
    Inventors: Naoki Kajiyama, Ayumi Arai, Eiichi Nakano, Hiroki Tatsumi, Teruo Watarai, Naoki Eisaki, Tatsuya Sakakibara, Masaru Suzuki
  • Publication number: 20020086370
    Abstract: The L-lysine-producing ability and the L-lysine-producing speed are improved in a coryneform bacterium harboring an aspartokinase in which feedback inhibition by L-lysine and L-threonine is substantially desensitized, by successively enhancing DNA coding for a dihydrodipicolinate reductase, DNA coding for a dihydrodipicolinate synthase, DNA coding for a diaminopimelate decarboxylase, and DNA coding for a diaminopimelate dehydrogenase.
    Type: Application
    Filed: December 8, 1997
    Publication date: July 4, 2002
    Inventors: SEIKO OTSUNA, MASAKAZU SUGIMOTO, MASAKO IZUI, ATSUSHI HAYAKAWA, EIICHI NAKANO, MASAKI KOBAYASHI, YASUHIKO YOSHIHARA, TSUYOSHI NAKAMATSU
  • Publication number: 20010049735
    Abstract: A calculation service providing system, comprising calculation servers, a Web server and terminals which are connected to one another on a network, wherein each of the calculation servers stores one or more applications for providing calculation service, wherein the Web server stores and publishes on the network one or more procedure data files, in each of which procedure data defining a calculation service using the one or more applications stored in one or more of the calculation servers is described, and wherein each of the terminals executes a procedure processing program for having one or more of the calculation servers execute one or more applications on the basis of the procedure data described in the procedure data file downloaded from the Web server.
    Type: Application
    Filed: May 25, 2001
    Publication date: December 6, 2001
    Inventors: Eiichi Nakano, Hitoshi Nonomura
  • Patent number: 6127157
    Abstract: The present invention provides a coating suitable for coating woods, and the coating is obtained by dissolving proanthocyanidine into water or a water-containing alcohol.
    Type: Grant
    Filed: May 3, 1999
    Date of Patent: October 3, 2000
    Assignees: Kikkoman Corporation, Noda Institute for Scientific Research
    Inventors: Osamu Hatamoto, Eiichi Nakano
  • Patent number: 6090597
    Abstract: A coryneform bacterium in which a DNA coding for a diaminopimelate decarboxylase and a DNA coding for a diaminopimelate dehydrogenase are enhanced is cultivated in a medium to allow L-lysine to be produced and accumulated in a culture, and L-lysine is collected from the culture.
    Type: Grant
    Filed: May 7, 1997
    Date of Patent: July 18, 2000
    Assignee: Ajinomoto Co., Inc.
    Inventors: Seiko Hirano, Masakazu Sugimoto, Eiichi Nakano, Masako Izui, Atsushi Hayakawa, Yasuhiko Yoshihara, Tsuyoshi Nakamatsu
  • Patent number: 5942427
    Abstract: N-acetylmannosamine dehydrogenase gene derived from a microorganism belonging to the genus Flavobacterium, e.g., Flavobacterium sp. No. 141-8 strain and defined by a specific restriction enzyme map which encodes 271 amino acid sequence. Using the recombinant DNA, N-acetylmannosamine dehydrogenase can be produced in a simpler manner in an industrial scale. The enzyme is useful for quantitative determination of sialic acid.
    Type: Grant
    Filed: December 27, 1990
    Date of Patent: August 24, 1999
    Assignees: Noda Institute for Scientific Research, Kikkoman Corporation
    Inventors: Hideko Otake, Yasuji Koyama, Tatsuo Horiuchi, Eiichi Nakano
  • Patent number: 5665584
    Abstract: The present invention relates to a DNA fragment of 3,563 base pairs containing a gene coding for tannase and derived from a microorganism belonging to the genus Aspergillus, with the following restriction enzyme map: ##STR1## B: Bam HI, H: Hind III, K: Kpn I, S: Sal I, X: Xba I; a DNA fragment containing a tannase gene coding for the amino acid sequence of (SEQ ID NO:4); a recombinant plasmid comprising the DNA fragment containing the tannase gene inserted into a plasmid vector; a process for producing tannase, comprising culturing a microorganism belonging to the genus Aspergillus capable of producing tannase in medium with the recombinant plasmid, and recovering tannase from the culture; and a promoter represented by the nucleotide sequence of (SEQ ID NO:1). Tannase can be efficiently produced according to the present invention.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: September 9, 1997
    Assignees: Noda Institutute For Scientific Research, Kikkoman Corporation
    Inventors: Osamu Hatamoto, Teruo Watarai, Kiyoshi Mizusawa, Eiichi Nakano
  • Patent number: 5435156
    Abstract: A method and an apparatus for the continuous pretreatment of a long cloth produced commercially in completely gaseous system, in which, by utilizing the combination of a desizing and scouring process in a low temperature plasma atmosphere and a bleaching process in an atmosphere of ozone and ultraviolet ray radiation, and thus entirely no application of liquid system.
    Type: Grant
    Filed: April 18, 1994
    Date of Patent: July 25, 1995
    Assignee: Sando Iron Works Co., Ltd.
    Inventors: Yoshiteru Sando, Eiichi Nakano, Hiroshi Ishidoshiro, Koji Sando
  • Patent number: 5432071
    Abstract: The present invention relates to variant E.sub.1 protein of pyruvate dehydrogenase complex of high activity in which arginine at the 146-position is replaced by proline in the amino acid sequence of wild-type E.sub.1 protein of pyruvate dehydrogenase complex, a gene coding for said variant E.sub.1 protein, a novel recombinant DNA comprising said variant E.sub.1 protein-encoding gene inserted in a vector DNA, and a process for producing variant E.sub.1 protein by said recombinant DNA. The present invention provides the variant E.sub.1 protein of pyruvate dehydrogenase complex of high activity.
    Type: Grant
    Filed: March 22, 1994
    Date of Patent: July 11, 1995
    Assignee: Kikkoman Corporation
    Inventors: Toshio Ichikawa, Yasuji Koyama, Hideko Otake, Eiichi Nakano
  • Patent number: 5407446
    Abstract: A method and an apparatus for the continuous pretreatment of a long cloth produced commercially in completely gaseous system, in which, by utilizing the combination of a desizing and scouring process in a low temperature plasma atmosphere and a bleaching process in an atmosphere of ozone and ultraviolet ray radiation, and thus entirely no application of liquid system.
    Type: Grant
    Filed: October 6, 1993
    Date of Patent: April 18, 1995
    Assignee: Sando Iron Works Co., Ltd.
    Inventors: Yoshiteru Sando, Eiichi Nakano, Hiroshi Ishidoshiro, Koji Sando
  • Patent number: 5370707
    Abstract: A method for bleaching a cloth comprising subjecting a cloth soaked with an aqueous bleaching solution comprising sodium chlorite to wet heat treatment at a temperature nearly to 100.degree. C., particularly subjecting a long cloth soaked with the bleaching solution to wet heat treatment continuously in an ordinary pressure wet heat treating chamber of which atmosphere being acidified to a pH of 3-4 by the use of an activation agent for making the atmosphere containing sodium chlorite acidic comprising an inorganic acid such as sulfuric acid and hydrochloric acid, an organic acid such as formic acid and acetic acid, and a carbonyl compound such as formaldehyde and acetaldehyde so as to form chlorine dioxide active for the bleaching of a cloth by the decomposition of sodium chlorite, and apparatuses for carrying out the method.
    Type: Grant
    Filed: March 20, 1991
    Date of Patent: December 6, 1994
    Assignee: Sando Iron Works Co., Ltd.
    Inventors: Yoshiteru Sando, Eiichi Nakano, Hiroshi Ishidoshiro, Koji Sando
  • Patent number: 5352598
    Abstract: A purified luciferase from Luciola lateralis is disclosed. The enzyme is characterized by having properties including: an optimum pH range of 7.5 to 9.5, an optimum temperature range of 0.degree. C. to 50.degree. C., and that the enzyme does not act on ADP, CTP, UTP, and GTP. The enzyme is purified by using a process which includes: gel filtration chromatography, hydroxyapatite column chromatography, and a tris(hydroxy)aminomethane-hydro-chloric acid buffer.
    Type: Grant
    Filed: August 29, 1991
    Date of Patent: October 4, 1994
    Assignee: Kikkoman Corporation
    Inventors: Naoki Kajiyama, Tsutomu Masuda, Hiroki Tatsumi, Eiichi Nakano
  • Patent number: 5334511
    Abstract: The present invention provides an improved mink growth hormone gene, a recombinant DNA containing the improved mink growth hormone gene, microorganisms which belong to the genus Escherichia and contain the recombinant DNA and which are capable of producing a mink growth hormone, and a method for producing a mink growth hormone using the E.coli transformant containing the recombinant DNA. According to the present invention, a mink growth hormone is efficiently produced.
    Type: Grant
    Filed: October 16, 1992
    Date of Patent: August 2, 1994
    Assignee: Kikkoman Corporation
    Inventors: Yasuhiro Harada, Eiichi Nakano, Hiroki Tatsumi, Motoaki Umezu
  • Patent number: 5334224
    Abstract: A method for the pretreatment of a long cloth continuously in which a cloth to be subjected to desizing, scouring and bleaching for the pretreatment thereof is preliminarily subjected to souring treatment in the sodium chlorite solution prepared by absorbing the chlorine dioxide gas, which is exhausted from the subsequent bleaching process with the use of chlorite, in a solution of H.sub.2 O.sub.2 and NaOH, and accordingly it is possible to transport the long cloth continuously in the pretreating process speedily with no need of staying the cloth in folded state for increasing the productivity and improving the quality of the product, and further to render the pretreating apparatus compact so as suitable for the production of small lot products.
    Type: Grant
    Filed: March 3, 1993
    Date of Patent: August 2, 1994
    Assignee: Sando Iron Works Co., Ltd.
    Inventors: Yoshiteru Sando, Eiichi Nakano, Hiroshi Ishidoshiro, Koji Sando
  • Patent number: 5330906
    Abstract: The present invention provides industrially useful luciferase. Mutant luciferase of the invention is produced by culturing a microorganism belonging to the genus Escherichia which harbors a recombinant DNA containing the mutant luciferase gene of a firefly. Mutant luciferase can produce red, orange or green color of light which can not be produced by wild type luciferase. Mutant luciferase can be used to measure ATP accurately in a colored solution such as red (e.g., blood), orange, or green in which wild-type luciferase has not provided reliable results.
    Type: Grant
    Filed: June 15, 1993
    Date of Patent: July 19, 1994
    Assignee: Kikkoman Corporation
    Inventors: Naoki Kajiyama, Eiichi Nakano
  • Patent number: 5254470
    Abstract: Alkaline protease which has leucine or isoleucine in the place of valine at the amino acid number 40 of wild type alkaline protease, a gene encoding the amino acid sequence of alkaline protease which has the substitution as described above, a recombinant DNA comprising said gene, a method of producing the above described alkaline protease, and a DNA fragment used for the expression of a gene.
    Type: Grant
    Filed: March 20, 1991
    Date of Patent: October 19, 1993
    Assignee: Japanese Research and Development Association for Improvement of Enzyme Function in Food Industry
    Inventors: Seiji Murakami, Hiroki Tatsumi, Yoshihiro Ogawa, Eiichi Nakano, Hiroshi Motai, Shigetoshi Sugio, Atsushi Masaki, Yutaka Ishida, Kohji Murakami, Haruhide Kawabe, Hirofumi Arimura
  • Patent number: 5234463
    Abstract: A method for desizing and scouring of a long length of cloth comprising desizing a cloth washed with hot water, and then subjecting the cloth thus washed successively to soaking with a hot alkaline sodium chlorite solution, immersing in a hot acid solution with a pH of 2-4, then to soaking with a caustic soda solution, and finally to the wet heat treatment under the ordinary pressure.
    Type: Grant
    Filed: September 9, 1991
    Date of Patent: August 10, 1993
    Assignee: Sando Iron Works Co., Ltd.
    Inventors: Yoshiteru Sando, Eiichi Nakano, Hiroshi Ishidoshiro, Koji Sando