Abstract: A powered fastener driver includes a first cylinder, a first piston positioned within the first cylinder, a second cylinder in fluid communication with the first cylinder, and a second piston positioned within the second cylinder. The first piston is moveable between a top-dead-center position and at or near a bottom-dead-center position and the second piston is moveable between a top-dead-center position and a bottom-dead-center position to initiate a fastener driving cycle. A drive blade is coupled to the second piston for movement therewith and a drive mechanism is configured to drive the first piston between the top-dead-center position and at or near the bottom-dead-center position. The drive mechanism includes a crank arm that rotates less than 360 degrees for moving the first piston from at or near the bottom-dead-center position and the top-dead-center position and then back to at or near the bottom-dead-center position to complete the fastener driving cycle.

Abstract: Host systems for resuming operation of a virtual compute instance may be identified that support features enabled for the virtual compute instance. Virtual compute instance features may be enabled at runtime prior to a virtual compute instance being stopped. When a virtual compute instance is started again, these features may be used to identify a host system that supports at least these features so that when the virtual compute instance resumes operation on the identified host, the features can be enabled.

Abstract: A method, computer system, and a computer program for data selection is provided. The present invention may include generating a first model associated with a dataset. The present invention may further include determining a first model performance level associated with the first model based on a plurality of dataset metric values of the dataset. The present invention may further include a plurality of data subsets of a dataset based on the first model performance level failing to exceed a performance threshold and calculating a plurality of subset metric values associated with the plurality of data subsets. The present invention may further include generating a second model associated with at least one data subset based on the plurality of subset metric values and determining an optimization associated with the first model based on a second model performance level associated with the second model exceeding the performance threshold.

Abstract: In one embodiment, a method performed by a computing device executing an analytics application used in conjunction with a patient management application, the method comprising: receiving workflows and events from the patient management application, the workflows and events corresponding to patient data; selectively processing the workflows and events in extract, transform, and load (ETL) pipelines responsive to trigger points in the workflows; and loading, by the ETL pipelines, data resulting from the selective processing into a data analytics data structure used to enable visualization of patient data and derived metrics or key performance indicators.

Abstract: Various methods are provided for facilitating access to linked information to GPS or short-range wireless equipped devices. One example method may comprise receiving, via a network, an indication of an interaction between a primary device and a third-party device, the indication comprising at least a first element and a second element, the first element indicative of user identification information and the second element indicative of at least one of a location or a bounded region, determining, as a function of at least the first element and the second element, a data object that upon validation is configured for use a subsequent interaction, and transmitting, to a mobile device, an electronic communication comprising an indication, configured for rendering on the mobile device, of the data object.

Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.

Abstract: Some embodiments provide novel methods for providing a set of services for a logical network associated with an edge forwarding element acting between a logical network and an external network. In some embodiments, the services are provided using a logical service forwarding plane that connects the edge forwarding element to a set of service nodes that each provide a service in the set of services. The service classification operation of some embodiments identifies a chain of multiple service operations that has to be performed on the data message. In some embodiments, identifying the chain of service operations includes selecting a service path to provide the multiple services. After selecting the service path, the data message is sent along the selected service path to have the services provided.

Abstract: The present invention relates to method of identifying a selective BRISC inhibitor. The present invention also relates to a stable BRISC dimer. The present invention further relates to use of the stable BRISC dimer to generate cryo-Electron Microscopy (cryo-EM), crystallography, nuclear magnetic resonance and/or X-ray crystallography structures for structure guided drug design.

Abstract: The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in stably transformed whole plant, or a cell suspension culture system.

Abstract: The present disclosure is directed towards a formulation for piezoelectric materials. The formulation may be printed including 2D or 3D printing. The formulation contains ceramic particles, a sol-gel, a high boiling point solvent and a binder.

Abstract: A system or method for drilling includes autonomously controlling a rotary or percussive drilling process as it transitions through multiple materials with very different dynamics. The method determines a drilling medium based on real-time measurements and comparison to prior drilling data, and identifies the material type, drilling region, and approximately optimal setpoint based on data from at least one operating condition. The controller uses these setpoints initially to execute an optimal search to maximize performance by minimizing mechanical specific energy. Near-bit depth-of-cut estimations are performed using a machine learning prediction deployed in an embedded processor to provide high-speed ROP estimates. The sensing capability is coupled with a near-bit clutching mechanism to support drilling dysfunction mitigation.

Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.

Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.

Abstract: A power tool battery pack receptacle includes a cavity in which a portion of a battery pack is receivable, an insertion end, a closed end opposite the insertion end along an insertion axis of the battery pack, and a rail extending between the insertion end and the closed end. The rail includes a first portion having a variable height and a second portion having a substantially constant height. The first portion is positioned adjacent the insertion end and the second portion is spaced from the insertion end. The rail is configured to be received within a groove of the battery pack.

Abstract: Techniques that facilitate feedback loop learning between artificial intelligence systems are provided. In one example, a system includes a monitoring component and a machine learning component. The monitoring component identifies a data pattern associated with data for an artificial intelligence system. The machine learning component compares the data pattern to historical data patterns for the artificial intelligence system to facilitate modification of at least a component of the artificial intelligence system and/or one or more dependent systems of the artificial intelligence system.

Abstract: Provided herein are ionic self-assembling peptides, pharmaceutical compositions comprising the peptides, and methods of using and making the same.

Abstract: A method of monitoring both liner wear and charge impact in an industrial mill uses a sensor mounted on an elongated element deployed through a shell into a liner of the mill. The elongated element wears at a same rate as the liner under conditions within the shell. Liner wear is related to a reduction in length of the elongated element as measured by travel time of an ultrasound wave, while location and strength of charge impact is related to change in amplitude of vibrations caused by the charge impact. Liner wear measurement can be improved by using shear ultrasound waves instead of conventional longitudinal ultrasound waves. A mill monitoring apparatus has a means for acquiring ultrasonic waves and audible sound waves using the same digitizer; a means for determining the angular position of the monitoring apparatus; and a means for supplying electric power to the apparatus.

Abstract: A method includes: accessing a part model comprising a three-dimensional representation of a part; accessing a material profile relating exposure energy and three-dimensional polymerization geometry of a material selected for the part; segmenting the part model into a set of model layers; detecting a first upward-facing surface in the part model; defining a first model volume in a first model layer, adjacent the first upward-facing surface, and fully contained within the part model; based on the material profile, calculating a first exposure energy predicted to yield a first three-dimensional polymerization geometry approximating a first contour of the first upward-facing surface when projected onto the material during a build; populating a first print image with the first exposure energy in a first image area corresponding to the first model volume in the first model layer; and storing the first print image in a print file for the part.

Abstract: Provided herein are ionic self-assembling peptides, pharmaceutical compositions comprising the peptides, and methods of using and making the same.

Abstract: Disclosed herein are systems and methods for neural interfaces. Neural interfaces may form minimally invasive and high-scalable bidirectional brain-computer interfaces, which may be used in the treatment of a variety of disorders of the brain and nervous system. Disclosed are methods for a minimally invasive technique for implanting neural interfaces, a neural interface configured to be placed between the brain and the dura and configured to record from and/or stimulate the cortical surface. Also disclosed are methods for attaching a plurality of microelectrode arrays to form a neural interface device, and fabricating neural interfaces including microelectrode arrays and pockets to facilitate their insertion. The disclosed systems and methods also include neural decoding techniques.