Abstract: A drill guide assembly for drilling a tunnel having a fixed, non-zero radius of curvature, where the drill guide assembly includes a housing and a sleeve, or cutting tube, configured to reciprocate within the distal portion where the sleeve, or cutting tube, is configured to receive a bone cutting instrument.

Abstract: A stent delivery system is disclosed that has an outer assembly and an inner assembly that accommodates a stent. The inner assembly further has an external assembly contact area projecting from its surface that frictionally contacts an inner surface of the outer assembly. The contact area is positioned at one end of the inner assembly, proximal to the stent accommodating area. Also disclosed is a method of using the stent delivery system.

Abstract: A machine tool that includes a workpiece support and a punching die. The punching die includes a support surface, for supporting a workpiece to be processed, and a discharging slope. The discharging slope is configured such that a workpiece part, severed from a workpiece supported on the support surface of the punching die, is displaced, in at least one of a rotational, tilting, or linear movement, from a processing position at least partially overlying the discharging slope toward a removal position on the discharging slope. The discharging slope is also configured such that a workpiece part, severed from a workpiece supported on the support surface of the punching die, is directed, in a sliding movement, toward a discharging position located beneath the support surface and adjacent the punching die.

Abstract: A client computing device receives a search request including an identifier and an identifier prefix. The computing device determines the identifier prefix and generates a uniform resource locator (URL) corresponding to the identifier prefix by inserting the identifier into a template such that the URL is configured to facilitate a specific request depending on the determined identifier prefix. Alternatively, a client computing device receives a search request and retrieves a search result comprising a uniform resource identifier (URI) having a domain name. The client computing device generates a hyperlink corresponding to the search result, the hyperlink effecting access of additional information related to a resource indicated by the URI having the domain name. The computing device generates enhanced search results by combining the search result and the hyperlink.

Abstract: A catheter having a distal tip comprising two sections of different hardness, and a method of making the same, is herein disclosed. The first section of the two sections is distal to the second section of the two sections and the second section is comprised of a material that is harder than the material of the first section. Additionally, the distal tip is bonded to a catheter shaft and the material of the catheter shaft is harder than the material of the first and second sections. The material of the catheter shaft, first section, and second section can comprise polyether block amide, with each section and the catheter shaft having different properties.

Abstract: A water/slurry containment device for core drilling can contain and allow water/slurry to be extracted while the coring is occurring rather than allowing a puddle to form with more extensive cleanup required afterward. The device contains the water/slurry mix so that none escapes the confines of the device, so that water can be used in the core drilling. Water is essential to the life of the diamond coated bit and it keeps dust and noise to a minimum. The device includes a base plate with a collector ring that can rest on a surface to be core drilled. A notch can be cut in the collector ring and/or base plate to allow water and slurry to be removed from the device while core drilling.

Abstract: A self-optimizing energy harvester comprises a thermoelectric generator coupling to a thermal source, producing a source voltage greater than a minimum start-up voltage, where the thermoelectric generator drives a boost circuit and a feedforward circuit, delivering power to a load. A conventional boost circuit has a maximum output power only at the input voltage for which a fixed set point resistor is chosen. The feedforward circuit dynamically optimizes the boost circuit according to a dynamic set point resistance, thus increasing output power for a wide range of input voltages, relative to using a fixed reference resistor. The dynamic set point resistance is the sum of a variable resistance and a reference resistance. A sample element forms a differential voltage between the source and input voltage elements, and the variable resistance corresponds to the differential voltage. A reference resistor is chosen to establish the minimum start-up voltage.

Abstract: A DNS server receives a DNS query based on a predetermined syntax, with the DNS query having a domain name having a highest level domain (HLD). The DNS server uses a root zone file having a resource record to resolve the DNS query in response to determining that the HLD is a top level domain alias (TLDA) that is not an HLD registered in the DNS server. The resource record of the root zone file includes an IP address corresponding to a network resource that is configured to determine a namespace provider that can process the domain name having the TLDA.

Abstract: A Domain Name System (DNS) server of a conventional DNS includes a DNS query having a highest level domain (HLD), a root zone having at least one root resource record adapted to resolve said DNS query when it is determined that said HLD is a top level domain alias (TLDA).

Abstract: Systems and methods for air cooling a microfluidic device using confinement channels to isolate cooling air from exposed liquids are disclosed. The systems and methods may also thermally condition the cooling airflow for improved robustness of the microfluidic device. In one embodiment, the air cooling system includes a split-level cooling manifold including an inlet duct that directs cooling air to a microfluidic device and an outlet duct that directs air heated by the microfluidic device away from the microfluidic device. The temperature of cooling air may be measured. The cooling air may be preheated to a temperature that is higher than an expected ambient temperature. The temperature of the cooling air after being heated by a microfluidic device may be measured.

Abstract: A drainage stent delivery system including a stent, a guide catheter, a push catheter, and an outer sheath. The guide catheter extends through the lumen of the stent and the push catheter is disposed over a portion of the guide catheter proximal of the distal end of the stent. The outer sheath is slidably disposed over the push catheter and surrounding at least a portion of the stent. The outer sheath may be actuated from a first position in which a distal portion of the outer sheath surrounds the stent to a second position in which the distal portion of the outer sheath is proximal of the stent. The stent delivery system may also include a retention mechanism for selectively coupling the stent to the outer sheath which may selectively decouple the stent from the outer sheath through rotational and/or translational motion of the outer sheath relative to the stent.

Abstract: The present invention relates generally to systems and methods for the rapid serial processing of multiple nucleic acid assays. More particularly, the present invention provides for the real time processing of nucleic acid during polymerase chain reaction (PCR) and thermal melt applications. According to an aspect of the invention, a system for the rapid serial processing of multiple nucleic acid assays is provided. In one embodiment, the system includes, but is not limited to: a microfluidic cartridge having microfluidic (flow-through) channels, a fluorescence imaging system, a temperature measurement and control system; a pressure measurement and control system for applying variable pneumatic pressures to the microfluidic cartridge; a storage device for holding multiple reagents (e.g.

Abstract: A drainage stent delivery system including an elongate shaft of a medial device, a drainage catheter or stent, and a retention mechanism for selectively retaining the drainage stent on the elongate shaft. The tubular stent is positioned on and surrounding the elongate shaft. The elongate shaft includes a distal tip portion which is deflectable from a first position to a second position, the distal tip portion of the elongate shaft being biased toward the first position. Deflecting the distal tip portion of the elongate shaft from the first position to the second position moves the distal tip portion toward the central longitudinal axis of the tubular stent to allow the stent to be decoupled from the elongate shaft.

Abstract: A client computing device receives a search request including an identifier and an identifier prefix. The computing device determines the identifier prefix and generates a uniform resource locator (URL) corresponding to the identifier prefix by inserting the identifier into a template such that the URL is configured to facilitate a specific request depending on the determined identifier prefix. Alternatively, a client computing device receives a search request and retrieves a search result comprising a uniform resource identifier (URI) having a domain name. The client computing device generates a hyperlink corresponding to the search result, the hyperlink effecting access of additional information related to a resource indicated by the URI having the domain name. The computing device generates enhanced search results by combining the search result and the hyperlink.

Abstract: A WHOIS record of a domain name is retrieved at a first time, the WHOIS record including an expiry date of a second time, a time difference value can be calculated between the first time and the second time, and the time difference value provided to a user. Time difference value can be determined to satisfy at least one condition including a threshold value. An indication can be provided to the user that the at least one condition has been satisfied such as notifying the user of domain name expiration status, storing the domain name in a user expiration watch list, monitoring the domain name for expiration upon or after the second time, and attempting to register the domain name with a selected domain name registration provider after the second time or upon determining that either the domain name may soon be available for registration or available for registration.

Abstract: An accessible URI may be generated in response to determining that an existing valid URI is inaccessible. When a valid URI is determined to be not accessible, then a valid URI may be generated to access content by extracting keywords from the non-query component URI (e.g., directory, domain, port, or fragment, etc.) of the inaccessible URI and using such keywords as a search request or as the query portion of the generated accessible URI.

Abstract: When a user retrieves a web page from a network and it is determined that the web page can be accessed from the network with a resource location request including a Uniform Resource Identifier (URI) having one or more URI components, one or more domain names can be generated from at least one of a one or more URI components and at least a portion of the web page, and the user can be provided a copy of the web page from the network along with the ability to determine whether at least one domain name of said one or more domain names is available for registration.