Patents by Inventor Ezio Bombardelli

Ezio Bombardelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200113961
    Abstract: Disclosed are compositions including one or more essential oils selected from oils deriving from citrus fruits, Lavandula officinalis or Cinnamomum cassia. The compositions may preferably be administered topically. The compositions are useful in the prevention and/or treatment of insomnia and anxiety, and in reducing appetite and stimulating the metabolism.
    Type: Application
    Filed: April 9, 2018
    Publication date: April 16, 2020
    Inventor: Ezio BOMBARDELLI
  • Patent number: 10583162
    Abstract: The present invention relates to compositions comprising: a) a Vitis vinifera extract in free form or in the form of a complex with phospholipids, or a Punica granatum extract; and b) a lipophilic extract of Zingiber officinale; and c) a lipophilic extract obtained from plants containing polyunsaturated fatty acid isobutylamides selected from the group consisting of Echinacea spp. extract or Zanthoxylum spp. extract or Acmella oleracea (or Spilanthes oleracea) extract; and d) an unsaponifiable fraction of olive oil and/or corn oil; or e) N-acetyl glucosamine; or f) diacerein; and their use in the prevention and/or treatment of osteoarticular inflammation and pain, and cartilage damage.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: March 10, 2020
    Assignee: Indena S.P.A.
    Inventor: Ezio Bombardelli
  • Publication number: 20190151396
    Abstract: The present invention relates to compositions comprising: a) a Vitis vinifera extract in free form or in the form of a complex with phospholipids, or a Punica granatum extract; and b) a lipophilic extract of Zingiber officinale; and c) a lipophilic extract obtained from plants containing polyunsaturated fatty acid isobutylamides selected from the group consisting of Echinacea spp. extract or Zanthoxylum spp. extract or Acmella oleracea (or Spilanthes oleracea) extract; and d) an unsaponifiable fraction of olive oil and/or corn oil; or e) N-acetyl glucosamine; or f) diacerein; and their use in the prevention and/or treatment of osteoarticular inflammation and pain, and cartilage damage.
    Type: Application
    Filed: June 28, 2017
    Publication date: May 23, 2019
    Applicant: Indena S.P.A.
    Inventor: Ezio Bombardelli
  • Patent number: 10286028
    Abstract: The present invention relates to compositions containing, as their only active ingredients, an extract of Curcuma spp, optionally as curcumin in the form of a complex with phospholipids, and an extract selected from Echinacea spp extract or lipophilic extract of Zanthoxylum spp, which are useful in the topical and systemic treatment of peripheral pain and of superficial and deep inflammatory and painful conditions. The compositions according to the invention are particularly effective in the treatment of osteoarthritis and rheumatoid arthritis in patients unable to tolerate long-term treatment with NSAIDs or steroids.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: May 14, 2019
    Assignee: INDENA S.P.A.
    Inventor: Ezio Bombardelli
  • Publication number: 20190083392
    Abstract: The present invention relates to compositions comprising at least one film-forming agent able to adhere in a stable way to the mucosa of the mouth, esophagus and upper airways, establishing a mechanical form of protection against attack on said mucosae. Said compositions are useful in the prevention and/or treatment of disorders of the oral cavity, esophagus and upper airways caused by bacterial and/or viral agents and/or by chemical agents.
    Type: Application
    Filed: March 15, 2017
    Publication date: March 21, 2019
    Applicant: Indena S.P.A.
    Inventor: Ezio Bombardelli
  • Patent number: 10220065
    Abstract: The present invention relates to compositions consisting of a combination of a lipophilic extract of Zingiber officinale and an extract of Cynara scolymus, which are useful for the prevention and treatment of oesophageal reflux and irritable bowel syndrome, to reduce postprandial drowsiness, and having prokinetic and anti-dyspeptic activities.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: March 5, 2019
    Assignee: INDENA S.P.A.
    Inventor: Ezio Bombardelli
  • Patent number: 10149877
    Abstract: The present invention relates to combinations of an agent that stimulates cell proliferation and an anti-inflammatory/analgesic, which are useful in the treatment of peripheral ulcers of various origins, such as radiation dermatitis, diabetic ulcers, ulcers caused by venous stasis of the limbs, bedsores, and the associated skin infections, proctitis, vulvovaginitis and haemorrhoids with vascular lesions. These combinations can be presented as formulations for topical use.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: December 11, 2018
    Assignee: INDENA S.P.A.
    Inventor: Ezio Bombardelli
  • Patent number: 10016478
    Abstract: Disclosed are compositions containing an extract of Serenoa repens, a lipophilic extract of Zingiber officinalis and a lipophilic extract of Echinacea angustifolia or Zanthoxylum bungeanum.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: July 10, 2018
    Assignee: Indena S.P.A.
    Inventors: Ezio Bombardelli, Paolo Morazzoni
  • Publication number: 20180125918
    Abstract: Disclosed are compositions containing: a) Phaseolus vulgaris extract; b) Cynara scolymus extract; c) Echinacea angustifolia extract; d) Vitis vinifera extract and optionally e) Panax ginseng extract, mixed with suitable excipients.
    Type: Application
    Filed: January 9, 2018
    Publication date: May 10, 2018
    Applicant: Indena S.P.A.
    Inventors: Ezio Bombardelli, Fabrizio Corti
  • Patent number: 9901610
    Abstract: Disclosed are compositions containing: a) Phaseolus vulgaris extract; b) Cynara scolymus extract; c) Echinacea angustifolia extract; d) Vitis vinifera extract and optionally e) Panax ginseng extract, mixed with suitable excipients.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: February 27, 2018
    Assignee: INDENA S.P.A.
    Inventors: Ezio Bombardelli, Fabrizio Corti
  • Patent number: 9839663
    Abstract: Disclosed is a combination of lipophilic extracts of Zingiber officinale and Echinacea angustifolia for the treatment of itching, peripheral pain, superficial and deep inflammatory and painful states, pain associated with muscle spasms, herpes pain, and radiodermatitis caused by oncological radiotherapy, with or without fungal or bacterial infections.
    Type: Grant
    Filed: February 4, 2016
    Date of Patent: December 12, 2017
    Assignee: INDENA S.P.A.
    Inventors: Ezio Bombardelli, Paolo Morazzoni
  • Publication number: 20170333508
    Abstract: Extract obtainable by extraction from Phaseolus sp. with mixtures of ethanol and water, characterised by an ?-amylase inhibitor content in between 1,000 and 1,600 USP/mg (HPLC titre between 6 and 14% w/w) and a phytohaemagglutinin content in between 8,000 and 30,000 HAU/g, and a process for its preparation.
    Type: Application
    Filed: July 7, 2017
    Publication date: November 23, 2017
    Inventors: DAVIDE BERLANDA, MARCO BERTANI, EZIO BOMBARDELLI, ANDREA GARDI, CESARE PONZONE, FABIO DONZELLI
  • Publication number: 20170304341
    Abstract: Methods for treating and preventing mucositis, in particular mucositis following the administration of chemotherapy drugs or a combination of said drugs with radiotherapy, are disclosed herein. More specifically, disclosed herein is the administration of a therapeutically effective amount of at least one of an anthocyanoside, a proanthocyanidin, or an extract containing at least one of an anthocyanoside or a proanthocyanidin for the treatment or prevention of mucositis. The therapeutically effective amount of the anthocyanoside, proanthocyanidin or extract can be administered alone or in combination with a therapeutically effective amount of at least one of an anti-inflammatory agent, immunomodulating agent, analgesic, antimicrobial agent or antifungal agent. Also disclosed herein are pharmaceutical compositions for treating and preventing mucositis.
    Type: Application
    Filed: July 12, 2017
    Publication date: October 26, 2017
    Applicant: Indena S.p.A.
    Inventors: Ezio Bombardelli, Paolo Morazzoni
  • Publication number: 20170281708
    Abstract: Disclosed are compositions containing an extract of Serenoa repens, a lipophilic extract of Zingiber officinalis and a lipophilic extract of Echinacea angustifolia or Zanthoxylum bungeanum.
    Type: Application
    Filed: June 19, 2017
    Publication date: October 5, 2017
    Applicant: Indena S.P.A.
    Inventors: Ezio Bombardelli, Paolo Morazzoni
  • Patent number: 9770475
    Abstract: The present invention relates to compositions containing a combination of a cell proliferation-stimulating agent with vasokinetic properties and an antimicrobial, antifungal and antiviral agent with an anti-inflammatory/analgesic, which is useful in the treatment of peripheral ulcers of various origins, such as diabetic ulcers, ulcers caused by venous stasis of the limbs, bedsores and the associated skin infections. Said combination could be presented as formulations for topical or systemic use.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: September 26, 2017
    Assignee: INDENA S.P.A.
    Inventors: Ezio Bombardelli, Paolo Morazzoni, Massimo Ronchi
  • Patent number: 9730974
    Abstract: Disclosed are compositions containing an extract of Serenoa repens, a lipophilic extract of Zingiber officinalis and a lipophilic extract of Echinacea angustifolia or Zanthoxylum bungeanum.
    Type: Grant
    Filed: May 7, 2014
    Date of Patent: August 15, 2017
    Assignee: INDENA S.P.A.
    Inventors: Ezio Bombardelli, Paolo Morazzoni
  • Patent number: 9730952
    Abstract: Methods for treating and preventing mucositis, in particular mucositis following the administration of chemotherapy drugs or a combination of said drugs with radiotherapy, are disclosed herein. More specifically, disclosed herein is the administration of a therapeutically effective amount of at least one of an anthocyanoside, a proanthocyanidin, or an extract containing at least one of an anthocyanoside or a proanthocyanidin for the treatment or prevention of mucositis. The therapeutically effective amount of the anthocyanoside, proanthocyanidin or extract can be administered alone or in combination with a therapeutically effective amount of at least one of an anti-inflammatory agent, immunomodulating agent, analgesic, antimicrobial agent or antifungal agent. Also disclosed herein are pharmaceutical compositions for treating and preventing mucositis.
    Type: Grant
    Filed: August 16, 2010
    Date of Patent: August 15, 2017
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombardelli, Paolo Morazzoni
  • Patent number: 9687468
    Abstract: The present invention relates to the preparation of Cynara scolymus leaf extracts, which are useful for the prevention and treatment of dyslipidaemia, in particular to increase HDL cholesterol in patients at cardiovascular risk. Said extracts are useful to normalize the lipid and carbohydrate balances and significantly increase the value of HDL cholesterol by favorably changing the LDL/HDL ratio, especially in post-infarction patients with drug-induced dyslipidaemia.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: June 27, 2017
    Assignee: INDENA S.P.A.
    Inventor: Ezio Bombardelli
  • Publication number: 20170049840
    Abstract: The present invention relates to compositions containing, as their only active ingredients, an extract of Curcuma spp, optionally as curcumin in the form of a complex with phospholipids, and an extract selected from Echinacea spp extract or lipophilic extract of Zanthoxylum spp, which are useful in the topical and systemic treatment of peripheral pain and of superficial and deep inflammatory and painful conditions. The compositions according to the invention are particularly effective in the treatment of osteoarthritis and rheumatoid arthritis in patients unable to tolerate long-term treatment with NSAIDs or steroids.
    Type: Application
    Filed: February 18, 2015
    Publication date: February 23, 2017
    Inventor: Ezio Bombardelli
  • Patent number: 9566309
    Abstract: Disclosed are compositions containing extracts of (a) Panax ginseng C. A. Mayer, (b) Zingiber officinale, (c) Echinacea angustifolia and (d) Silybum marianum or the phospholipid complex of silybin with phospholipids as active ingredients, mixed with suitable excipients.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: February 14, 2017
    Assignee: INDENA S.P.A.
    Inventors: Ezio Bombardelli, Fabrizio Corti