Patents by Inventor Ezio Bombardelli

Ezio Bombardelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8287926
    Abstract: Combinations of vasoactive substances which are useful in the treatment of sexual dysfunctions associated with poor local blood supply and/or insufficient lubrication are provided. The vasoactive compounds are esculoside, visnadine, forskolin or extracts thereof, purified lipophilic extracts from plants of the genus Ipomea, esters of ximenynic acid, icarin or icarin derivatives, amentoflavone, and Gingko biloba dimeric flavones. The combination of these vasoactive substances is incorporated in gels and lotions designed to be applied to the genital organs. These formulations are useful in inducing erection of the male and female sex organs and enhancing orgasm and sexual performance. The formulations are particularly useful in the treatment of female sexual dysfunctions.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: October 16, 2012
    Assignee: Indena S.p.A.
    Inventor: Ezio Bombardelli
  • Patent number: 8226994
    Abstract: The invention provides formulations containing sanguinarine, chelerythrine or chelidonine or their salts or extracts containing them, mixed with suitable vehicles and/or excipients, for the treatment of common skin warts and verrucas, anal and vulvar warts and psoriatic plaques.
    Type: Grant
    Filed: March 9, 2009
    Date of Patent: July 24, 2012
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombardelli, Gabriele Fontana, Paolo Morazzoni, Antonella Riva, Massimo Ronchi
  • Patent number: 8217053
    Abstract: Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: July 10, 2012
    Assignee: Indena S.p.A.
    Inventors: Gabriele Fontana, Ezio Bombardelli, Carla Manzotti, Arturo Battaglia, Maria Grazia Allegri, legal representative, Cristian Samoriā€²
  • Patent number: 8211479
    Abstract: Compositions comprising: vasokinetic natural coumarins or extracts containing them; anti-phosphodiesterase agents selected from 3,7-O-di-(2-hydroxyethyl)icaritin or 7-O-hydroxyethyl-icariside II and/or forskolin or extracts containing them; phytoestrogens selected from ferutinine or ferutinine-containing extracts of Ferula sp. or p-pivaloylferutinine.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: July 3, 2012
    Assignee: Indena S.p.A.
    Inventor: Ezio Bombardelli
  • Patent number: 8206759
    Abstract: Combinations of vasoprotective agents useful for the treatment of reducing blood cholesterol and triglyceride levels induced by an excess of plasma lipids. The agents include polycosanols, tocotriends and/or lycopene, procyanidole oligomers and vegetable oil rich in insaturated fatty acids.
    Type: Grant
    Filed: February 24, 2011
    Date of Patent: June 26, 2012
    Assignee: Indena S.p. A.
    Inventor: Ezio Bombardelli
  • Patent number: 8193210
    Abstract: Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
    Type: Grant
    Filed: July 16, 2007
    Date of Patent: June 5, 2012
    Assignee: Indena S.p.A.
    Inventors: Gabriele Fontana, Ezio Bombardelli, Carla Manzotti, Arturo Battaglia, Maria Grazia Allegri, legal representative, Cristian Samori
  • Publication number: 20120095094
    Abstract: The invention relates to a process for cosmetic treatment, including the reduction of superficial and deep wrinkles, using ferutinine from Ferula spp extracts.
    Type: Application
    Filed: December 13, 2011
    Publication date: April 19, 2012
    Applicant: INDENA S.P.A.
    Inventors: Ezio BOMBARDELLI, Gabriele Fontana, Aldo Cristoni, Enrico Mercalli
  • Publication number: 20120040031
    Abstract: The present invention relates to compositions consisting of a combination of lipophilic extracts of Zingiber officinale and Echinacea angustifolia, obtained by extraction with carbon dioxide under supercritical conditions, which are useful for the prevention and treatment of oesophageal reflux and chemotherapy-induced emesis.
    Type: Application
    Filed: January 15, 2010
    Publication date: February 16, 2012
    Applicant: INDENA S.P.A.
    Inventor: Ezio Bombardelli
  • Publication number: 20120015060
    Abstract: The present invention relates to compositions consisting of a combination of a lipophilic extract of Zingiber officinale and an extract of Cynara scolymus, which are useful for the prevention and treatment of oesophageal reflux and irritable bowel syndrome, to reduce postprandial drowsiness, and having prokinetic and anti-dyspeptic activities.
    Type: Application
    Filed: January 15, 2010
    Publication date: January 19, 2012
    Applicant: INDENA S.P.A.
    Inventor: Ezio Bombardelli
  • Publication number: 20120009283
    Abstract: Combinations of vasoactive substances which are useful in the treatment of sexual dysfunctions associated with poor local blood supply and/or insufficient lubrication are provided. The vasoactive compounds are esculoside, visnadine, forskolin or extracts thereof, purified lipophilic extracts from plants of the genus Ipomea, esters of ximenynic acid, icarin or icarin derivatives, amentoflavone, and Gingko biloba dimeric flavones. The combination of these vasoactive substances is incorporated in gels and lotions designed to be applied to the genital organs. These formulations are useful in inducing erection of the male and female sex organs and enhancing orgasm and sexual performance. The formulations are particularly useful in the treatment of female sexual dysfunctions.
    Type: Application
    Filed: September 22, 2011
    Publication date: January 12, 2012
    Applicant: INDENA S.P.A.
    Inventor: Ezio BOMBARDELLI
  • Patent number: 8092844
    Abstract: This invention relates to combinations of vasoactive substances which are useful in the treatment of sexual dysfunctions associated with poor local blood supply and/or insufficient lubrication. The active compounds are selected from a: esculoside or visnadine; forskolin or extracts containing it, or alternatively, purified lipophilic extracts of plants of the genus Ipomea; esters of ximenynic acid; optionally, at least one compound selected from a icarin or derivatives or extracts thereof which contain it, amentoflavone, and Gingko biloba dimeric flavones. The combination of these vasoactive substances is incorporated in gels and lotions designed to be applied to the genital organs. These formulations are useful in inducing erection of the male and female sex organs and enhancing orgasm and sexual performance. The formulations are particularly useful in the treatment of female sexual dysfunctions.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: January 10, 2012
    Assignee: Indena S.p.A.
    Inventor: Ezio Bombardelli
  • Patent number: 8076351
    Abstract: Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them.
    Type: Grant
    Filed: July 12, 2007
    Date of Patent: December 13, 2011
    Assignee: Indena S.p.A.
    Inventors: Gabriele Fontana, Ezio Bombardelli, Carla Manzotti, Arturo Battaglia, Maria Grazia Allegri, legal representative, Cristian Samori
  • Patent number: 7993683
    Abstract: Compositions comprising: saligenin or derivatives thereof or Salix ssp extracts containing from 10 to 50% of saligenin; substantially pure andrographolide or andrographolide enriched Andrographis paniculata extract containing from 5 to 30% of andrographolide; optionally N-acetyl-glucosamine and/or glucuronic acid or glucuronolactone.
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: August 9, 2011
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombardelli, Paolo Morazzoni
  • Patent number: 7976881
    Abstract: Combinations of vasoactive substances which act at venous or arterial level with phosphodiesterase inhibitors including phosphodiesterase V, in particular: visnadin or esculoside; at least one compound selected from icarin or derivatives thereof or extracts containing it, Gingko biloba dimeric flavones either in the free form or complexed with phospholipids, amentoflavone; at least one compound selected from escin, escin beta-sitosterol complexed with phospholipids, sericoside, sericoside complexed with phospholipids or Centella asiatica extract in the free form or complexed with phospholipids. The formulations are useful in reducing parmiculopathy and problems associated with venous insufficiency of the lower limbs.
    Type: Grant
    Filed: July 6, 2004
    Date of Patent: July 12, 2011
    Assignee: Indena S.p.A.
    Inventor: Ezio Bombardelli
  • Publication number: 20110142967
    Abstract: Combinations of vasoprotective agents useful for the treatment of reducing blood cholesterol and triglyceride levels induced by an excess of plasma lipids. The agents include polycosanols, tocotriends and/or lycopene, procyanidole oligomers and vegetable oil rich in insaturated fatty acids.
    Type: Application
    Filed: February 24, 2011
    Publication date: June 16, 2011
    Applicant: INDENA S.P.A.
    Inventor: Ezio BOMBARDELLI
  • Publication number: 20110135769
    Abstract: The present invention relates to compositions based on benzophenanthridine alkaloids, extract of Hippophae rhamnoides and extract of Echinacea angustifolia which possess antibacterial, antiviral and anti-inflammatory activity, and are useful in the treatment of bacterial and viral infections of the upper respiratory tract, and in the treatment of influenza.
    Type: Application
    Filed: May 25, 2009
    Publication date: June 9, 2011
    Applicant: INDENA S.P.A.
    Inventor: Ezio Bombardelli
  • Publication number: 20110104313
    Abstract: The present invention relates to compositions comprising benzofuran compounds and benzophenanthridine alkaloids, which possess anti-inflammatory, antibacterial and antifungal activity useful in the treatment of vaginal infections and the resulting inflammatory states.
    Type: Application
    Filed: April 6, 2009
    Publication date: May 5, 2011
    Applicant: INDENA S.P.A
    Inventors: Ezio Bombardelli, Gabriele Fontana, Andrea Giori, Paolo Morazzoni, Antonella Riva, Massimo Ronchi
  • Publication number: 20110091392
    Abstract: The present invention relates to compositions comprising benzophenanthridine alkaloids, benzofuran compounds and catechin polyphenols, which are useful in the treatment and prevention of infections of the oral cavity.
    Type: Application
    Filed: April 6, 2009
    Publication date: April 21, 2011
    Applicant: INDENA S.P.A
    Inventors: Ezio Bombardelli, Gabriele Fontana, Andrea Giori, Paolo Morazzoni, Antonella Riva, Massimo Ronchi
  • Patent number: 7910139
    Abstract: Compositions for the treatment of the affections of the oral cavity and upper respiratory tract include anthocyanosides, procyanidins and phloroglucinols. The anthocyanosides are derived from Vaccinium myrtillus extract, the procyanidins are derived from a Vitus vinifera extract, a Camellia sinensis extract or from other edible plants containing procyanidins, and the phloroglucinols are derived from Hypericum spp., Myrtus spp. or Humulus lupulus extracts.
    Type: Grant
    Filed: November 4, 2004
    Date of Patent: March 22, 2011
    Assignee: Indena S.p.A.
    Inventor: Ezio Bombardelli
  • Patent number: RE43280
    Abstract: The use of the reduction products of hyperforin and adhyperforin, pharmaceutically acceptable salts or esters thereof, in the pharmaceutical and/or nutritional field, in particular in the treatment of depression and Alzheimer's disease.
    Type: Grant
    Filed: April 18, 2003
    Date of Patent: March 27, 2012
    Assignee: Indena S.p.A.
    Inventors: Ezio Bombardelli, Paolo Morazzoni, Antonella Riva, Nicola Fuzzati