Patents by Inventor Frits Goedegebuur

Frits Goedegebuur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10913919
    Abstract: An automatic dishwashing cleaning composition having a new protease.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: February 9, 2021
    Assignee: The Procter & Gamble Company
    Inventors: Frits Goedegebuur, David Aaron Estell, Lilia Maria Babe, Thijs Kaper, Viktor Alekseyev, Sina Pricelius, Hatice Billur Engin, Harm Jan Mulder, Sander Van Stigt-Thans, Eva Maria Perez-Prat Vinuesa
  • Publication number: 20200392477
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: December 19, 2017
    Publication date: December 17, 2020
    Inventors: Lilia Maria Babe, Lydia Dankmeyer, David A. Estell, Frits Goedegebuur, Thijs Kaper, Harm Mulder, Sina Pricelius
  • Publication number: 20200354708
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability compared to one or more reference subtilisin.
    Type: Application
    Filed: November 28, 2018
    Publication date: November 12, 2020
    Inventors: Lilia Maria Babe, Viktor Yuryevich Alekseyev, Joshua Roy Basler, H. Billur Engin, David A. Estell, Roopa Santosh Ghirnikar, Frits Goedegebuur, Thijs Kaper, Mulder Harm, Sina Pricelius, Thans Sander Van Stigt
  • Publication number: 20200291374
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases, polynucleotides encoding the novel metalloproteases, and compositions and methods for use thereof.
    Type: Application
    Filed: May 22, 2020
    Publication date: September 17, 2020
    Inventors: LILIA M. BABE, FRITS GOEDEGEBUUR, ROOPA GHIRNIKAR, XIAOGANG GU, MARC KOLKMAN, JIAN YAO
  • Publication number: 20200248160
    Abstract: The present disclosure relates to serine proteases cloned from Bacillus gibsonii, and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: December 4, 2019
    Publication date: August 6, 2020
    Inventors: MARC KOLKMAN, FRITS GOEDEGEBUUR, LILIA MARIA BABE, RIE MEJLDAL, HARM MULDER, ANJA HEMMINGSEN KELLETT-SMITH, RICHARD R BOTT, MILES CHRISTOPHER SCOTCHER
  • Patent number: 10731144
    Abstract: The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include polynucleotides encoding serine protease sequences with modified or heterologous propeptide regions; polypeptides comprising serine proteases with modified or heterologous propeptide regions; expression cassettes, DNA constructs, vectors, and chromosomes comprising such polynucleotides; and bacterial host cells comprising such polynucleotides. The methods include methods for enhancing the production of mature proteases in bacterial host cells (e.g. Bacillus sp. host cells). The produced proteases find use in the industrial production of enzymes, suitable for use in various industries, including but not limited to the cleaning, animal feed and textile processing industry.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: August 4, 2020
    Assignee: DANISCO US INC
    Inventors: Lilia Maria Babe, Carol Marie Fioresi, Frits Goedegebuur, Harm Mulder
  • Patent number: 10696958
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases, polynucleotides encoding the novel metalloproteases, and compositions and methods for use thereof.
    Type: Grant
    Filed: December 8, 2017
    Date of Patent: June 30, 2020
    Assignee: DANISCO US INC
    Inventors: Lilia M. Babe, Frits Goedegebuur, Roopa Ghirnikar, Xiaogang Gu, Marc Kolkman, Jian Yao
  • Publication number: 20200172837
    Abstract: The present disclosure relates to serine proteases and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: August 6, 2019
    Publication date: June 4, 2020
    Inventors: Marc Kolkman, Frits Goedegebuur, Harm Mulder, Lilia Maria Babe
  • Publication number: 20200123522
    Abstract: The present disclosure provides AprL-clade protease enzymes, including variant AprL-clade protease enzymes, nucleic acids encoding same, and compositions and methods related to the production and use thereof, including an AprL-clade variant subtilisin enzyme that has improved stability and/or soil removal compared to a parent AprL-clade subtilisin enzyme.
    Type: Application
    Filed: December 19, 2019
    Publication date: April 23, 2020
    Inventors: David A Estell, Frits Goedegebuur, Marc Anton Bernhard Kolkman, Rie Mejldal, Katherine Augustyn, Lilia Maria Babe, Richard R Bott, Jian Yao, Roopa Santosh Ghirnikar
  • Publication number: 20200115693
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.
    Type: Application
    Filed: December 17, 2019
    Publication date: April 16, 2020
    Inventors: Lilia Maria Babe, RICHARD R BOTT, ROOPA SANTOSH GHIRNIKAR, FRITS GOEDEGEBUUR, XIAOGANG GU, MARC ANTON BERNHAR KOLKMAN, JIAN YAO, SHUKUN YU
  • Publication number: 20200024552
    Abstract: An automatic dishwashing cleaning composition having a new protease.
    Type: Application
    Filed: June 13, 2019
    Publication date: January 23, 2020
    Inventors: Frits GOEDEGEBUUR, David Aaron ESTELL, Lilia Maria BABE, Thijs KAPER, Viktor ALEKSEYEV, Sina PRICELIUS, Hatice Billur ENGIN, Harm Jan MULDER, Sander VAN STIGT-THANS, Eva Maria PEREZ-PRAT VINUESA
  • Patent number: 10533165
    Abstract: The present disclosure relates to serine proteases cloned from Bacillus gibsonii, and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: January 14, 2020
    Assignee: DANISCO US INC
    Inventors: Marc Kolkman, Rie Mejldal, Frits Goedegebuur, Lilia Maria Babe, Anja Hemmingsen Kellett-Smith, Harm Mulder, Richard R. Bott, Miles Christopher Scotcher
  • Publication number: 20200010782
    Abstract: An automatic dishwashing cleaning composition having a new protease.
    Type: Application
    Filed: June 13, 2019
    Publication date: January 9, 2020
    Inventors: Frits GOEDEGEBUUR, David Aaron ESTELL, Lilia Maria BABE, Thijs KAPER, Viktor ALEKSEYEV, Sina PRICELIUS, Hatice Billur ENGIN, Harm Jan MULDER, Sander VAN STIGT-THANS, Eva Maria PEREZ-PRAT VINUESA
  • Publication number: 20190338267
    Abstract: The present invention provides protease compositions particularly suited for dishwashing applications.
    Type: Application
    Filed: July 23, 2019
    Publication date: November 7, 2019
    Inventors: Pieter Augustinus, Ayrookaran J. Poulose, Frits Goedegebuur, Johannes C. Van Der Laan
  • Publication number: 20190330610
    Abstract: Disclosed herein is one or more subtilisin variant. nucleic acid encoding same. and compositions and methods related to the production and use thereof. including one or more Bacillus gibsonii-clade subtilisin variant that has improved soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: December 19, 2017
    Publication date: October 31, 2019
    Inventors: Lilia Maria Babe, Lydia Dankmeyer, Frits Goedegebuur, Thijs Kaper, Harm Mulder, Sina Pricelius
  • Publication number: 20190309278
    Abstract: Disclosed herein is one or more subtilisin variants, nucleic acids encoding same, and compositions and methods related to the production and uses thereof, including one or more subtilisin variants that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: June 18, 2017
    Publication date: October 10, 2019
    Inventors: Richard R. Bott, David A. Estell, Frits Goedegebuur, Harm Mulder, Sina Pricelius
  • Publication number: 20190264187
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.
    Type: Application
    Filed: May 7, 2019
    Publication date: August 29, 2019
    Inventors: Lilia M Babe, Roopa Santosh Ghirnikar, Frits Goedegebuur, Xiaogang Gu, Marc Anton Bernhard Kolkman, Jian Yao, Shukun Yu
  • Publication number: 20190194577
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: September 7, 2018
    Publication date: June 27, 2019
    Inventors: LUIS G. CASCAO-PEREIRA, DAVID A. ESTELL, FRITS GOEDEGEBUUR, JAMES T. KELLIS, JR., AYROOKARAN J. POULOSE, BRIAN F. SCHMIDT, WOLFGANG AEHLE
  • Publication number: 20190185789
    Abstract: A phosphate-free automatic dishwashing cleaning composition including: a) a protease wherein the protease is a variant having at least 60% identity with the amino acid sequence of SEQ ID NO:1 or SEQ ID NO:2 including two negatively charged amino acid residues, aspartic acid (D) and/or glutamic acid (E), in positions 124-131 using the SEQ ID NO: 1 numbering and the SEQ ID NO:2, respectively; and b) from 10 to 50% by weight of the composition of a complexing agent system comprising from 0 to less than 30% by weight of the composition of citric acid.
    Type: Application
    Filed: December 12, 2018
    Publication date: June 20, 2019
    Inventors: Philip Frank Souter, Eva Maria Perez-Prat de Vinuesa, Lilia Maria Babe, David Aaron Estell, Frits Goedegebuur, Harm Jan Mulder, Sina Pricelius, Lydia Dankmeyer, Thijs Kaper, Hatice Billur Engin
  • Publication number: 20190185788
    Abstract: A phosphate-free automatic dishwashing cleaning composition comprising i) a protease wherein the protease is a variant having at least 60% identity with the amino acid sequence of SEQ ID NO:1 and comprising at least one amino acid substitution (using the SEQ ID NO: 1 numbering) selected from the group consisting of X54T; X126A, D, G, V, E, K, I; X127E, S, T, A, P, G, C; and X128E, C, T, D, P, G, L, Y, N; and ii) from 10 to 50% by weight of the composition of a complexing agent system comprising from 0 to less than 30% by weight of the composition of citric acid.
    Type: Application
    Filed: December 12, 2018
    Publication date: June 20, 2019
    Inventors: Michelle JACKSON, Eva Maria PEREZ-PRAT de VINUESA, David John TARBIT, Philip Frank SOUTER, Lilia Maria BABE, David Aaron ESTELL, Frits GOEDEGEBUUR, Harm Jan MULDER, Sina PRICELIUS, Lydia DANKMEYER, Thijs KAPER, Hatice Billur ENGIN