Patents by Inventor Frits Goedegebuur

Frits Goedegebuur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protease Variants Active over a Broad Temperature Range
    Publication number: 20140302590
    Abstract: The present invention provides protease compositions particularly suited for dishwashing applications.
    Type: Application
    Filed: April 7, 2014
    Publication date: October 9, 2014
    Applicant: Danisco US Inc.
    Inventors: Pieter Augustinus, Frits Goedegebuur, Ayrookaran J. Poulose, Johannes C. Van Der Laan
  • COMPOSITIONS AND METHODS COMPRISING A SUBTILISIN VARIANT
    Publication number: 20140295527
    Abstract: The present invention provides a Bacillus sp. subtilisin variant. In addition, the present invention provides automatic dishwashing compositions comprising this serine protease variant.
    Type: Application
    Filed: April 22, 2014
    Publication date: October 2, 2014
    Applicant: DANISCO US INC.
    Inventors: David A. Estell, Frits Goedegebuur, Ayrookaran J. Poulose
  • Variant humicola grisea CBH1.1
    Patent number: 8828702
    Abstract: Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
    Type: Grant
    Filed: January 17, 2013
    Date of Patent: September 9, 2014
    Assignee: Danisco US Inc.
    Inventors: Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Edmund Larenas
  • EGVII Endoglucanase and Nucleic Acids Encoding the Same
    Publication number: 20140234933
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
    Type: Application
    Filed: January 20, 2014
    Publication date: August 21, 2014
    Applicant: DANISCO US INC.
    Inventors: Nigel DUNN-COLEMAN, Frits GOEDEGEBUUR, Michael WARD, Jian YAO
  • EGVI Endoglucanase and Nucleic Acids Encoding the Same
    Publication number: 20140227756
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant EGVI proteins and methods for producing the same.
    Type: Application
    Filed: January 29, 2014
    Publication date: August 14, 2014
    Applicant: DANISCO US INC.
    Inventors: Nigel DUNN-COLEMAN, Frits GOEDEGEBUUR, Michael WARD, Jian YAO
  • CBH1 homologs and varian CBH1 cellulase
    Patent number: 8765440
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Grant
    Filed: March 25, 2011
    Date of Patent: July 1, 2014
    Assignee: Danisco US Inc.
    Inventors: Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Paulien Neefe
  • Variant CBH2 cellulases
    Patent number: 8715997
    Abstract: Described herein are variants of H. jecorina CBH2, a Cel6A enzyme. The present invention provides novel cellobiohydrolases that have altered thermostability.
    Type: Grant
    Filed: July 7, 2011
    Date of Patent: May 6, 2014
    Assignee: Danisco US Inc.
    Inventors: Wolfgang Aehle, Frits Goedegebuur, Lydia Dankmeyer, Colin Mitchinson, Paulien Neefe, Bradley Kelemen, Robert Caldwell, Pauline Teunissen
  • OVER EXPRESSION OF FOLDASES AND CHAPERONES IMPROVES PROTEIN PRODUCTION
    Publication number: 20140087443
    Abstract: The present teachings provide methods for increasing protein secretion, e.g., chymosin in filamentous fungi by co-expressing certain chaperone(s) and/or foldase(s). The present teachings also provide filamentous fungi containing certain chaperone(s) and/or foldase(s) and a protein of interest for increased secretion.
    Type: Application
    Filed: August 27, 2013
    Publication date: March 27, 2014
    Applicant: Danisco US Inc.
    Inventors: Frits Goedegebuur, Paulien Neef-Kruithof, Jeffrey P. Pucci, Michael Ward
  • Variant CBH1 cellulase
    Patent number: 8679817
    Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
    Type: Grant
    Filed: June 14, 2012
    Date of Patent: March 25, 2014
    Assignee: Danisco US Inc.
    Inventors: Anthony Day, Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Paulien Neefe-Kruithof, Mats Sandgren, Andrew Shaw, Jerry Stahlberg
  • Cellulase variants with improved expression, activity and stability, and use thereof
    Patent number: 8679816
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
    Type: Grant
    Filed: June 3, 2010
    Date of Patent: March 25, 2014
    Assignee: Danisco US Inc.
    Inventors: Wolfgang Aehle, Richard R. Bott, Benjamin Bower, Jonathan Caspi, David A. Estell, Frits Goedegebuur, Ronaldus W. J. Hommes, Thijs Kaper, Bradley Kelemen, Slavko Kralj, Johan Van Lieshout, Igor Nikolaev, Sander Van Stigt Thans, Louise Wallace, Gudrun Vogtentanz, Mats Sandgren
  • Cell culture compositions
    Patent number: 8674062
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6 (SEQ ID NO:1 encodes the full length endoglucanase; SEQ ID NO:4 encodes the mature form), and the corresponding endoglucanase VI amino acid sequence (“EGVI”; SEQ ID NO:3 is the signal sequence; SEQ ID NO:2 is the mature sequence). The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant EGVI proteins and methods for producing the same.
    Type: Grant
    Filed: November 13, 2007
    Date of Patent: March 18, 2014
    Assignee: Danisco US Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yiao
  • Variant CBH1.1
    Patent number: 8673611
    Abstract: Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
    Type: Grant
    Filed: July 5, 2012
    Date of Patent: March 18, 2014
    Assignee: Danisco US Inc.
    Inventors: Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Edmund Larenas
  • EGVII endoglucanase and nucleic acids encoding the same
    Patent number: 8658406
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
    Type: Grant
    Filed: June 17, 2013
    Date of Patent: February 25, 2014
    Assignee: Danisco US Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • Variant CBH1 cellulases
    Patent number: 8637294
    Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: January 28, 2014
    Assignee: Danisco US Inc.
    Inventors: Anthony Day, Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Paulien Neefe, Mats Sandgren, Andrew Shaw, Jerry Stahlberg
  • EGVII ENDOGLUCANASE AND NUCLEIC ACIDS ENCODING THE SAME
    Publication number: 20140004587
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
    Type: Application
    Filed: June 17, 2013
    Publication date: January 2, 2014
    Inventors: Nigel DUNN-COLEMAN, Frits GOEDEGEBUUR, Michael WARD, Jian YAO
  • Protease Variants Active over a Broad Temperature Range
    Publication number: 20130323816
    Abstract: The present invention provides protease compositions particularly suited for dishwashing applications.
    Type: Application
    Filed: April 25, 2013
    Publication date: December 5, 2013
    Applicant: DANISCO US INC.
    Inventors: Pieter Augustinus, Frits Goedegebuur, Ayrookaran J. Poulose, Johannes C. Van Der Laan
  • Over expression of foldases and chaperones improves protein production
    Patent number: 8546126
    Abstract: The present teachings provide methods for increasing protein secretion, e.g., chymosin in filamentous fungi by co-expressing certain chaperone(s) and/or foldase(s). The present teachings also provide filamentous fungi containing certain chaperone(s) and/or foldase(s) and a protein of interest for increased secretion.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: October 1, 2013
    Assignee: Danisco US Inc.
    Inventors: Frits Goedegebuur, Paulien Neefe-Kruithof, Jeffrey P. Pucci, Michael Ward
  • VARIANT HUMICOLA GRISEA CBH1.1
    Publication number: 20130244289
    Abstract: Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
    Type: Application
    Filed: January 17, 2013
    Publication date: September 19, 2013
    Applicant: DANISCO US INC.
    Inventors: Frits GOEDEGEBUUR, Peter GUALFETTI, Colin MITCHINSON, Edmund LARENAS
  • Compositions and methods comprising a subtilisin variant
    Patent number: 8530219
    Abstract: The present invention provides a Bacillus sp. subtilisin variant. In addition, the present invention provides compositions comprising this serine protease variant. In some embodiments, the present invention provides laundry and other non-automatic (i.e., hand) dishwashing cleaning compositions comprising this serine protease variant.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: September 10, 2013
    Assignee: Danisco US Inc.
    Inventors: David A. Estell, Frits Goedegebuur, Ayrookaran Poulose
  • EGVII endoglucanase and nucleic acids encoding the same
    Patent number: 8486667
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
    Type: Grant
    Filed: November 1, 2011
    Date of Patent: July 16, 2013
    Assignee: Danisco US Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao