Patents by Inventor Frits Goedegebuur

Frits Goedegebuur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL VARIANT HYPROCREA JECORINA CBH1 CELLULASES
    Publication number: 20160312202
    Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
    Type: Application
    Filed: January 21, 2016
    Publication date: October 27, 2016
    Inventors: Anthony DAY, Frits GOEDEGEBUUR, Peter GUALFETTI, Colin MITCHINSON, Paulien NEEFE, Mats SANDGREN, Andrew SHAW, Jerry STAHLBERG
  • Beta-glucosidase I variants with improved properties
    Patent number: 9447400
    Abstract: The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants.
    Type: Grant
    Filed: November 19, 2010
    Date of Patent: September 20, 2016
    Assignee: DANISCO US INC.
    Inventors: Richard R. Bott, Thijs Kaper, Bradley Kelemen, Frits Goedegebuur, Ronaldus Wilhelmus Hommes, Slavko Kralj, Paulien Kruithof, Igor Nikolaev, Wilhelmus Antonious Hendricus Van Der Kley, Johannes Franciscus Thomas Van Lieshout, Sander Van Stigt Thans, Gudrun Vogtentanz, Mats Sandgren
  • Compositions and methods comprising a subtilisin variant
    Patent number: 9434915
    Abstract: The present invention provides a Bacillus sp. subtilisin variant. In addition, the present invention provides automatic dishwashing compositions comprising this serine protease variant.
    Type: Grant
    Filed: February 5, 2015
    Date of Patent: September 6, 2016
    Assignee: Danisco US Inc.
    Inventors: David A. Estell, Frits Goedegebuur, Ayrookaran J. Poulose
  • Compositions and Methods Comprising LG12-CLADE Protease Variants
    Publication number: 20160222368
    Abstract: The present invention provides serine protease enzymes produced from LG12-clade enzymes. In addition, the present invention provides compositions comprising these protease enzymes. In some embodiments, the present invention provides cleaning compositions comprising at least one of these protease enzymes.
    Type: Application
    Filed: September 11, 2014
    Publication date: August 4, 2016
    Applicant: Danisco US Inc.
    Inventors: Lilia M. Babe, David A. Estell, Frits Goedegebuur, Richard R. Bott, Marc Kolkman, Harm Mulder, Brian F. Schmidt, Katherine Augustyn, Munroop Atwal, Abby Marquez
  • AUTOMATIC DISHWASHING DETERGENT COMPOSITION
    Publication number: 20160208198
    Abstract: The present invention is in the field of automatic dishwashing detergent compositions, as well as methods of making and using same. In particular, it relates to an automatic dishwashing detergent composition comprising a new protease. The automatic dishwashing detergent composition provides improved cleaning and finishing. In particular the composition of the invention provides better proteinaceous removal at the same level of other proteases available in the market. This also alternatively allows for the use of a lower level of the protease of the invention and therefore a more cost effective composition.
    Type: Application
    Filed: April 1, 2016
    Publication date: July 21, 2016
    Inventors: Philip Frank SOUTER, Glenn Steven WARD, Frits GOEDEGEBUUR, Ayrookaran Joseph POULOSE, David A. ESTELL, Richard Ray BOTT, Luis Gustavo CASCAO-PEREIRA
  • NOVEL METALLOPROTEASES
    Publication number: 20160160202
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.
    Type: Application
    Filed: May 29, 2014
    Publication date: June 9, 2016
    Inventors: Lilia M. Babe, Roopa Ghirnikar, Frits Goedegebuur, Xiaogang Gu, Marc Kolkman, Jian Yao, Shukun Yu
  • NOVEL METALLOPROTEASES
    Publication number: 20160122738
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases, polynucleotides encoding the novel metalloproteases, and compositions and methods for use thereof.
    Type: Application
    Filed: May 29, 2014
    Publication date: May 5, 2016
    Inventors: Lilia M. Babe, Roopa Ghirnikar, Frits Goedegebuur, Xiaogang Gu, Marc Kolkman, Jian Yao
  • NOVEL METALLOPROTEASES
    Publication number: 20160108388
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.
    Type: Application
    Filed: May 29, 2014
    Publication date: April 21, 2016
    Inventors: Lilia M. Babe, Roopa Ghirnikar, Frits Goedegebuur, Xiaogang Gu, Marc Kolkman, Jian Yao, Shukun Yu
  • NOVEL METALLOPROTEASES
    Publication number: 20160108387
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.
    Type: Application
    Filed: May 29, 2014
    Publication date: April 21, 2016
    Inventors: Lilia M. Babe, Richard R. Bott, Roopa Ghirnikar, Frits Goedegebuur, Xiaogang Gu, Marc Kolkman, Jian Yao, Shukun Yu
  • COMPOSITIONS AND METHODS COMPRISING THERMOLYSIN PROTEASE VARIANTS
    Publication number: 20160060611
    Abstract: The present invention provides serine protease—thermoslysine—variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: November 5, 2013
    Publication date: March 3, 2016
    Applicant: DANISCO US INC.
    Inventors: Viktor Yuryevich ALEKSEYEV, Lilia Maria BABE, David A. ESTELL, Frits GOEDEGEBUUR, Harm MULDER, Daniel Esteban TORRES PAZMINO, Jian YAO, Richard R. BOTT
  • PROTEASES COMPRISING ONE OR MORE COMBINABLE MUTATIONS
    Publication number: 20160010072
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Application
    Filed: June 29, 2015
    Publication date: January 14, 2016
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, Ayrookaran J. Poulose, Brian F. Schmidt
  • EGVII Endoglucanase and Nucleic Acids Encoding the Same
    Publication number: 20150299683
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
    Type: Application
    Filed: March 27, 2015
    Publication date: October 22, 2015
    Applicant: DANISCO US INC.
    Inventors: Nigel DUNN-COLEMAN, Frits GOEDEGEBUUR, Michael WARD, Jian YAO
  • COMPOSITIONS AND METHODS COMPRISING A SUBTILISIN VARIANT
    Publication number: 20150240192
    Abstract: The present invention provides a Bacillus sp. subtilisin variant. In addition, the present invention provides automatic dishwashing compositions comprising this serine protease variant.
    Type: Application
    Filed: February 5, 2015
    Publication date: August 27, 2015
    Applicant: DANISCO US INC.
    Inventors: David A. Estell, Frits Goedegebuur, Ayrookaran J. Poulose
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20150132825
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: November 10, 2014
    Publication date: May 14, 2015
    Applicant: DANISCO US INC.
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR., Ayrookaran J. Poulose, Brian F. Schmidt
  • EGVII endoglucanase and nucleic acids encoding the same
    Patent number: 9005948
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
    Type: Grant
    Filed: January 20, 2014
    Date of Patent: April 14, 2015
    Assignee: Danisco US Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • AUTOMATIC DISHWASHING DETERGENT COMPOSITION
    Publication number: 20150087572
    Abstract: The present invention is in the field of automatic dishwashing detergent compositions, as well as methods of making and using same. In particular, it relates to an automatic dishwashing detergent composition comprising a new protease. The automatic dishwashing detergent composition provides improved cleaning and finishing. In particular the composition of the invention provides better proteinaceous removal at the same level of other proteases available in the market. This also alternatively allows for the use of a lower level of the protease of the invention and therefore a more cost effective composition.
    Type: Application
    Filed: November 24, 2014
    Publication date: March 26, 2015
    Inventors: Philip Frank SOUTER, Glenn Steven WARD, Frits GOEDEGEBUUR, Ayrookaran Joseph POULOSE, David A. ESTELL, Richard Ray BOTT, Luis Gustavo CASCAO-PEREIRA
  • VARIANT HUMICOLA GRISEA CBH1.1
    Publication number: 20150079638
    Abstract: Disclosed are variants of Humicola grisea CeI7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
    Type: Application
    Filed: August 20, 2014
    Publication date: March 19, 2015
    Applicant: Danisco US Inc.
    Inventors: Frits GOEDEGEBUUR, Peter Gualfetti, Colin Mitchinson, Edmund Larenas
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20150031589
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: July 21, 2014
    Publication date: January 29, 2015
    Applicant: DANISCO US INC.
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR., Ayrookaran J. Poulose, Brian F. Schmidt
  • CELLULASE VARIANTS WITH IMPROVED EXPRESSION, ACTIVITY AND STABILITY, AND USE THEREOF
    Publication number: 20140302585
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
    Type: Application
    Filed: February 25, 2014
    Publication date: October 9, 2014
    Applicant: DANISCO US INC.
    Inventors: Wolfgang AEHLE, Richard R. BOTT, Benjamin S. BOWER, Jonathan CASPI, David A. ESTELL, Frits GOEDEGEBUUR, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Johannes Franciscus Thomas VAN LIESHOUT, Igor NIKOLAEV, Sander VAN STIGT THANS, Louise WALLACE, Gudrun VOGTENTANZ, Mats SANDGREN
  • NOVEL VARIANT HYPOCREA JECORINA CBH1 CELLULASE
    Publication number: 20140302584
    Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
    Type: Application
    Filed: February 25, 2014
    Publication date: October 9, 2014
    Applicant: DANISCO US INC.
    Inventors: Anthony DAY, Frits GOEDEGEBUUR, Peter GUALFETTI, Colin MITCHINSON, Paulien NEEFE, Mats SANDGREN, Andrew SHAW, Jerry STAHLBERG