Patents by Inventor Frits Goedegebuur

Frits Goedegebuur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190078070
    Abstract: The present invention provides protease compositions particularly suited for dishwashing applications.
    Type: Application
    Filed: May 15, 2018
    Publication date: March 14, 2019
    Inventors: Pieter Augustinus, Ayrookaran J. Poulose, Frits Goedegebuur, Johannes C. Van Der Laan
  • Publication number: 20180355340
    Abstract: The present invention is in the field of automatic dishwashing detergent compositions, as well as methods of making and using same. In particular, it relates to an automatic dishwashing detergent composition comprising a new protease. The automatic dishwashing detergent composition provides improved cleaning and finishing. In particular the composition of the invention provides better proteinaceous removal at the same level of other proteases available in the market. This also alternatively allows for the use of a lower level of the protease of the invention and therefore a more cost effective composition.
    Type: Application
    Filed: August 23, 2018
    Publication date: December 13, 2018
    Inventors: Philip Frank SOUTER, Glenn Steven WARD, Frits GOEDEGEBUUR, Ayrookaran Joseph POULOSE, David A. ESTELL, Richard Ray BOTT, Luis Gustavo CASCAO-PEREIRA
  • Patent number: 10093887
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Grant
    Filed: July 21, 2014
    Date of Patent: October 9, 2018
    Assignee: DANISCO US INC.
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, Jr., Ayrookaran J. Poulose, Brian F. Schmidt
  • Publication number: 20180237761
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more Bacillus gibsonii-clade subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: June 17, 2016
    Publication date: August 23, 2018
    Inventors: Lilia Maria Babe, Richard R. Bott, David A. Estell, Harm Mulder, Frits Goedegebuur, Jian Yao, Sina Pricelius, Miles Scotcher
  • Publication number: 20180216090
    Abstract: The present disclosure provides LG12-clade enzyme variants, compositions comprising these enzyme variants, and method of using these enzymes and compositions, as well as the polynucleotides encoding these enzymes, the vectors comprising these polynucleotides, and the host cells transformed with such vectors.
    Type: Application
    Filed: March 14, 2016
    Publication date: August 2, 2018
    Inventors: Harm Mulder, Jeffrey Veach Miller, Frits Goedegebuur, David A. Estell, Katherine Augustyn, Lilia Maria Babe, Richard R. Bott, Miles Christopher Scotcher, Jian Yao
  • Publication number: 20180155701
    Abstract: The present invention provides methods and compositions for the production of mature proteases in bacterial host cells. The compositions include polynucleotides encoding serine protease sequences with modified or heterologous propeptide regions; polypeptides comprising serine proteases with modified or heterologous propeptide regions; expression cassettes, DNA constructs, vectors, and chromosomes comprising such polynucleotides; and bacterial host cells comprising such polynucleotides. The methods include methods for enhancing the production of mature proteases in bacterial host cells (e.g. Bacillus sp. host cells). The produced proteases find use in the industrial production of enzymes, suitable for use in various industries, including but not limited to the cleaning, animal feed and textile processing industry.
    Type: Application
    Filed: June 17, 2016
    Publication date: June 7, 2018
    Applicant: DANISCO US INC.
    Inventors: Lilia Maria BABE, Carol Marie FIORESI, Frits GOEDEGEBUUR, Harm MULDER
  • Publication number: 20180112204
    Abstract: The present disclosure provides AprL-clade protease enzymes, including variant AprL-clade protease enzymes, nucleic acids encoding same, and compositions and methods related to the production and use thereof, including an AprL-clade variant subtilisin enzyme that has improved stability and/or soil removal compared to a parent AprL-clade subtilisin enzyme.
    Type: Application
    Filed: May 13, 2016
    Publication date: April 26, 2018
    Inventors: David A. Estell, Frits Goedegebuur, Marc Kolkman, Rie Mejldal, Katherine Augustyn, Lilia Maria Babe, Richard R. Bott, Jian Yao, Roopa Ghirnikar
  • Publication number: 20180087038
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases, polynucleotides encoding the novel metalloproteases, and compositions and methods for use thereof.
    Type: Application
    Filed: December 8, 2017
    Publication date: March 29, 2018
    Inventors: Lilia M. Babe, Frits Goedegebuur, Roopa Ghirnikar, Xiaogang Gu, Marc Kolkman, Jian Yao
  • Publication number: 20180080017
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.
    Type: Application
    Filed: November 30, 2017
    Publication date: March 22, 2018
    Inventors: XIAOGANG GU, FRITS GOEDEGEBUUR, MARC ANTON BERNHAR KOLKMAN, SHUKUN YU, LILIA MARIA BABE, ROOPA SANTOSH GHIRNIKAR, JIAN YAO
  • Publication number: 20180073006
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.
    Type: Application
    Filed: October 5, 2017
    Publication date: March 15, 2018
    Inventors: Lilia M. Babe, Richard R. Bott, Roopa Ghirnikar, Frits Goedegebuur, Xiaogang Gu, Marc Kolkman, Jian Yao, Shukun Yu
  • Patent number: 9896674
    Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
    Type: Grant
    Filed: January 21, 2016
    Date of Patent: February 20, 2018
    Assignee: DANISCO US INC
    Inventors: Anthony Day, Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Paulien Neefe, Mats Sandgren, Andrew Shaw, Jerry Stahlberg
  • Publication number: 20180030426
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant EGVI proteins and methods for producing the same.
    Type: Application
    Filed: May 15, 2017
    Publication date: February 1, 2018
    Inventors: FRITS GOEDEGEBUUR, JIAN YAO, MICHAEL WARD, NIGEL DUNN-COLEMAN
  • Publication number: 20180023068
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.
    Type: Application
    Filed: October 6, 2017
    Publication date: January 25, 2018
    Inventors: Lilia M. Babe, Roopa Ghirnikar, Frits Goedegebuur, Xiaogang Gu, Marc Kolkman, Jian Yao, Shukun Yu
  • Publication number: 20180002642
    Abstract: The present disclosure relates to serine proteases and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: October 27, 2015
    Publication date: January 4, 2018
    Inventors: Marc KOLKMAN, Frits GOEDEGEBUUR, Harm MULDER, Lilia Maria BABE
  • Publication number: 20170233710
    Abstract: The present disclosure relates to serine proteases cloned from Bacillus spp., and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: October 16, 2015
    Publication date: August 17, 2017
    Inventors: Marc Kolkman, Frits Goedegebuur, Harm Mulder, Richard R. Bott, Anja Hemmingsen Kellet-Smith, Lilia Maria Babe
  • Publication number: 20170145396
    Abstract: The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants.
    Type: Application
    Filed: August 29, 2016
    Publication date: May 25, 2017
    Applicant: DANISCO US INC.
    Inventors: Richard R. BOTT, Thijs KAPER, Bradley R. KELEMEN, Frits GOEDEGEBUUR, Ronaldus Wilhelmus Joannes HOMMES, Slavko KRALJ, Paulien KRUITHOF, Igor NIKOLAEV, Wilhelmus Antonious Hendricus VAN DER KLEY, Johannes Franciscus Thomas VAN LIESHOUT, Sander VAN STIGT THANS, Gudrun VOGTENTANZ, Mats SANDGREN
  • Patent number: 9644192
    Abstract: Disclosed are variants of Humicola grisea CeI7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: May 9, 2017
    Assignee: Danisco US Inc., Genencor Division
    Inventors: Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Edmund Larenas
  • Publication number: 20170029797
    Abstract: The present invention is in the field of automatic dishwashing detergent compositions, as well as methods of making and using same. In particular, it relates to an automatic dishwashing detergent composition comprising a new protease. The automatic dishwashing detergent composition provides improved cleaning and finishing. In particular the composition of the invention provides better proteinaceous removal at the same level of other proteases available in the market. This also alternatively allows for the use of a lower level of the protease of the invention and therefore a more cost effective composition.
    Type: Application
    Filed: October 17, 2016
    Publication date: February 2, 2017
    Inventors: Philip Frank SOUTER, Glenn Steven WARD, Frits GOEDEGEBUUR, Ayrookaran Joseph POULOSE, David A. ESTELL, Richard Ray BOTT, Luis Gustavo CASCAO-PEREIRA
  • Patent number: 9523087
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
    Type: Grant
    Filed: February 25, 2014
    Date of Patent: December 20, 2016
    Assignee: DANISCO US INC
    Inventors: Wolfgang Aehle, Richard R. Bott, Benjamin S. Bower, Jonathan Caspi, David A. Estell, Frits Goedegebuur, Ronaldus Wilhelmus Joannes Hommes, Thijs Kaper, Bradley R. Kelemen, Slavko Kralj, Johannes Franciscus Thomas Van Lieshout, Igor Nikolaev, Sander Van Stigt Thans, Louise Wallace, Gudrun Vogtentanz, Mats Sandgren
  • Publication number: 20160319266
    Abstract: The present disclosure relates to serine proteases cloned from Bacillus gibsonii, and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: December 12, 2014
    Publication date: November 3, 2016
    Applicant: Danisco US Inc.
    Inventors: Marc Kolkman, Rie Mejldal, Frits Goedegebuur, Lilia Maria Babe, Anja Hemmingsen Kellett-Smith, Harm Mulder, Richard R. Bott, Miles Christopher Scotcher