Patents by Inventor Frits Goedegebuur

Frits Goedegebuur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods Comprising A Subtilisin Variant
    Publication number: 20110281328
    Abstract: The present invention provides a Bacillus sp. subtilisin variant. In addition, the present invention provides compositions comprising this serine protease variant. In some embodiments, the present invention provides laundry and other non-automatic (i.e., hand) dishwashing cleaning compositions comprising this serine protease variant.
    Type: Application
    Filed: November 10, 2009
    Publication date: November 17, 2011
    Applicant: Danisco US Inc.
    Inventors: David A. Estell, Frits Goedegebuur, Ayrookaran Joseph Poulose
  • Compositions And Methods Comprising Variant Microbial Proteases
    Publication number: 20110251073
    Abstract: The present invention provides methods for protein engineering. Specifically, the invention provides methods utilizing site evaluation libraries to design libraries that optimize two or more properties of a protein. The present invention also provides variant subtilisins suitable for various uses.
    Type: Application
    Filed: June 3, 2009
    Publication date: October 13, 2011
    Inventors: Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR.
  • Novel Variant Hyprocrea Jecorina CBH1 Cellulases
    Publication number: 20110229956
    Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
    Type: Application
    Filed: May 13, 2011
    Publication date: September 22, 2011
    Applicants: Danisco US Inc., Genencor International, Inc.
    Inventors: Anthony Day, Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Paulien Neefe, Mats Sandgren, Andrew Shaw, Jerry Stahlberg
  • BGL3 Beta-Glucosidase and Nucleic Acids Encoding the Same
    Publication number: 20110212505
    Abstract: The present invention provides a novel ?-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.
    Type: Application
    Filed: May 6, 2011
    Publication date: September 1, 2011
    Applicant: Danisco US Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • Variant CBH2 cellulases
    Patent number: 8008056
    Abstract: Described herein are variants of H. jecorina CBH2, a Cel6A enzyme. The present invention provides novel cellobiohydrolases that have altered thermostability.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: August 30, 2011
    Assignee: Danisco US Inc.
    Inventors: Wolfgang Aehle, Frits Goedegebuur, Lydia Dankmeyer, Colin Mitchinson, Paulien Neefe, Brad Kelemen, Robert Caldwell, Pauline Teunissen
  • Variant CBH1.1
    Patent number: 7998711
    Abstract: Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: August 16, 2011
    Assignee: Danisco US Inc.
    Inventors: Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Edmund Larenas
  • Novel CBH1 Homologs And Varian CBH1 Cellulase
    Publication number: 20110177561
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Application
    Filed: March 25, 2011
    Publication date: July 21, 2011
    Applicant: Danisco US Inc.
    Inventors: Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Paulien Neefe
  • Variant CBH1 cellulases
    Patent number: 7972832
    Abstract: Described herein are variants of H. jecorina CBH I, a Cel7 enzyme. The present invention provides novel cellobiohydrolases that have improved thermostability and reversibility.
    Type: Grant
    Filed: August 15, 2003
    Date of Patent: July 5, 2011
    Assignee: Danisco US Inc.
    Inventors: Anthony Day, Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Paulien Neefe, Mats Sandgren, Andrew Shaw, Jerry Stahlberg
  • BGL3 beta-glucosidase and nucleic acids encoding the same
    Patent number: 7960146
    Abstract: The present invention provides a novel ?-glucosidase nucleic acid sequence, designated bgl3, and the corresponding BGL3 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL3, recombinant BGL3 proteins and methods for producing the same.
    Type: Grant
    Filed: August 17, 2007
    Date of Patent: June 14, 2011
    Assignee: Danisco US Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • CBH1 homologs and variant CBH1 cellulases
    Patent number: 7951570
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Grant
    Filed: October 13, 2008
    Date of Patent: May 31, 2011
    Assignee: Danisco US Inc.
    Inventors: Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Paulien Neefe
  • Variant CBH1.1
    Patent number: 7951571
    Abstract: Disclosed are variants of Humicola grisea Cel7A (CBH1.1), H. jecorina CBH1 variant or S. thermophilium CBH1, nucleic acids encoding the same and methods for producing the same. The variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted.
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: May 31, 2011
    Assignee: Danisco US Inc.
    Inventors: Frits Goedegebuur, Peter Gualfetti, Colin Mitchinson, Edmund Larenas
  • BGL4 Beta-Glucosidase and Nucleic Acids Encoding the Same
    Publication number: 20110086410
    Abstract: The present invention provides a novel ?-glucosidase nucleic acid sequence, designated bgl4, and the corresponding BGL4 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL4, recombinant BGL4 proteins and methods for producing the same.
    Type: Application
    Filed: November 13, 2007
    Publication date: April 14, 2011
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • CIP1 polypeptides and their uses
    Patent number: 7923235
    Abstract: Described herein are novel gene sequences isolated from Trichoderma reesei. Two genes encoding proteins comprising a cellulose binding domain, one encoding an arabionfuranosidase and one encoding an acetylxylanesterase are described. The sequences, CIP1 and CIP2, contain a cellulose binding domain. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.
    Type: Grant
    Filed: January 6, 2010
    Date of Patent: April 12, 2011
    Assignee: Danisco US Inc.
    Inventors: Pamela Foreman, Pieter Van Solingen, Frits Goedegebuur, Michael Ward
  • Protease Variants Active Over A Broad Temperature Range
    Publication number: 20110059517
    Abstract: The present invention provides protease compositions particularly suited for dishwashing applications.
    Type: Application
    Filed: November 17, 2010
    Publication date: March 10, 2011
    Inventors: Pieter Augustinus, Frits Goedegebuur, Ayrookaran J. Poulose, Johannes C. Van Der Laan
  • EGVI endoglucanase and nucleic acids encoding the same
    Patent number: 7811799
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant EGVI proteins and methods for producing the same.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: October 12, 2010
    Assignee: Danisco US Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • EGVI endoglucanase and nucleic acids encoding the same
    Patent number: 7807434
    Abstract: The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant EGVI proteins and methods for producing the same.
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: October 5, 2010
    Assignee: Danisco US Inc.
    Inventors: Nigel Dunn-Coleman, Frits Goedegebuur, Michael Ward, Jian Yao
  • CIP1 Polypeptides and their uses
    Publication number: 20100203593
    Abstract: Described herein are novel gene sequences isolated from Trichoderma reesei. Two genes encoding proteins comprising a cellulose binding domain, one encoding an arabionfuranosidase and one encoding an acetylxylanesterase are described. The sequences, CIP1 and CIP2, contain a cellulose binding domain. These proteins are especially useful in the textile and detergent industry and in pulp and paper industry.
    Type: Application
    Filed: January 6, 2010
    Publication date: August 12, 2010
    Inventors: Pamela Foreman, Pieter Van Solingen, Frits Goedegebuur, Michael Ward
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20100192985
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: November 10, 2009
    Publication date: August 5, 2010
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR., Ayrookaran J. Poulose, Brian F. Schmidt
  • COMPOSITIONS AND METHODS COMPRISING A SUBTILISIN VARIANT
    Publication number: 20100152087
    Abstract: The present invention provides a subtilisin variant that is particularly well suited to cleaning applications. In particular, the present invention provides a Bacillus sp. subtilisin variant and cleaning compositions comprising this variant.
    Type: Application
    Filed: November 10, 2009
    Publication date: June 17, 2010
    Inventors: Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR., Ayrookaran J. Poulise
  • COMPOSITIONS AND METHODS COMPRISING A SUBTILISIN VARIANT
    Publication number: 20100152088
    Abstract: The present invention provides a Bacillus sp. subtilisin variant. In addition, the present invention provides automatic dishwashing compositions comprising this serine protease variant.
    Type: Application
    Filed: November 10, 2009
    Publication date: June 17, 2010
    Inventors: David A. Estell, Frits Goedegebuur, Ayrookaran J. Poulose