Abstract: An in vivo device and a method for collecting and measuring oximetry data in a body lumen, such as using a swallowable capsule. The in vivo device may include instruments for collecting oximetry data, for example an illuminator and an oximetry data detector.

Abstract: A device, system and method for in-vivo analysis. An autonomous in-vivo device may include a magnet to detain at least a portion of a sample collected from a body lumen; a sensor to sense a property of the detained sample portion; and a transmitter to transmit data of the sensed property.

Abstract: The present invention relates mainly to a method and apparatus for monitoring bodily analytes, such as glucose, by use of an analyzer (100) configured for emitting radiation oriented to impinge on a selected area of the skin (S), for collecting returned imprinted radiation exiting the skin, for processing and analysis of the imprinted radiation, and for display of analysis results. At least one retroreflector (RR, RI 1, R1 & 2) is inserted subcutaneously to the selected area (SA) for receiving radiation and returning retroreflected radiation, as returned imprinted radiation. The retroreflector (RR, R1 1, R1 & 2) has at least one level of retroreflection (RR1L, RR2L).

Abstract: The present invention provides an optical system for illuminating and viewing a target in which an illumination element and a receiving means are disposed behind a single optical window, and which obtains data essentially free of backscatter and stray light. The optical window of the optical system is configured such that it defines a shape having at least one focal curve, i.e., an ellipsoid shaped dome. The illumination element and the receiving means are geometrically positioned on the focal curve plane or in proximity of the focal curve plane, such that, when illuminating, rays from the illumination elements, that are internally reflected from the optical window, will not be incident on the receiving means.

Abstract: Embodiments of the invention are directed to methods and systems associated with a disposable dispenser (100, 200) of therapeutic fluid. Preferred embodiments having a small size of less than about 75 mm in length, less than 50 mm in width and less than about 10 mm in thickness and may be releasably attached to the body (B). In one embodiments, the dispenser draws fluid from a flexible volume-conformable reservoir (4) and operates a dosing and metering pump (6, 61, 62, 63) incorporating a motor to deliver fluid through a fluid delivery tool (8, 81, 82). Disposed on the housing bottom (2B) is a peel-of-tape (22) that when removed, electrically connects a power supply (18) to power the operative components (3) of the dispenser into operation, exposes an adhesive (28) and a window (21) opened in the housing (2), and allows the fluid delivery tool (8) to extend for insertion into the skin (S).

Abstract: One or more therapeutic fluids, such as for example insulin can be delivered to a body. In addition or alternatively, the concentrations of one or more analytes can be measured in vivo. A feedback process can be used to regulate levels of the one or more analytes based on the measurements via delivery of the one or more therapeutic fluids. Related systems, apparatus, methods, and/or articles are also described.

Abstract: Embodiments of the present invention are directed to devices, systems and methods for delivering therapeutic fluid (e.g., insulin) into the body, including a skin adherable cradle, for retaining a therapeutic fluid dispenser for delivering a therapeutic fluid to a user.

Abstract: A device, system and method for in-vivo sampling. An in-vivo device and method for use thereof may include a sampling chamber and a gating mechanism. The sampling chamber may store a sample of a body lumen substance, and the gate may close and open an opening of the sampling chamber.

Abstract: Devices, systems and methods for in-vivo imaging include, for example, a separator configured to separate a light, reflected from a body lumen, into at least one separated-color light, and optionally an analyzer configured to analyze the at least one separated-color light.

Abstract: The present invention provides an optical system for illuminating and viewing a target in which an illumination element and a receiving means are disposed behind a single optical window, and which obtains data essentially free of backscatter and stray light. The optical window of the optical system is configured such that it defines a shape having at least one focal curve, i.e., an ellipsoid shaped dome. The illumination element and the receiving means are geometrically positioned on the focal curve plane or in proximity of the focal curve plane, such that, when illuminating, rays from the illumination elements, that are internally reflected from the optical window, will not be incident on the receiving means.

Abstract: There is provided an imager with, for example, a fiber plate cover capable of transferring to a sensor element an image of a sample that may be close to or in contact with such fiber plate cover, and imaging such sample. An imager may include a fiber plate cover capable of capturing images from a microarray analysis device. There is also provided a method of capturing images with an imager of a sample that is for example in contact with a fiber plate cover on such imager.

Abstract: An optical imaging system comprising: a taking lens system that collects light from a scene being imaged with the optical imaging system; a 3D camera comprising at least one photosurface that receives light from the taking lens system simultaneously from all points in the scene and provides data for generating a depth map of the scene responsive to the light; and an imaging camera comprising at least one photosurface that receives light from the taking lens system and provides a picture of the scene responsive to the light.

Abstract: A semiconductor surface is provided comprising a plurality of light sensitive pixels wherein each pixel of the plurality of pixels comprises an electronic circuit formed on or in the semiconductor surface, the circuit comprising: a photosensor that generates a signal responsive to light incident thereon at an output thereof; and circuitry that provides a signal responsive to a time lapse between a first time responsive to said signal and a reference time. There is also provided a 3D camera incorporating the semiconductor surface.

Abstract: A device, method and system for sensing the temperature or temperature change of an environment. A typically in-vivo device includes an image sensor. The device may sense the dark current noise of the image sensor, and calculate the temperature or a temperature change of the image sensor.

Abstract: A device, system and method may enable the obtaining of in vivo information other than or in addition to images from for example within body lumens or cavities, such as temperature, pressure, or pH from the gastrointestinal (GI) tract, where the data is typically transmitted or otherwise sent via an optical means to a receiving system.

Abstract: An energy saving method for acquiring in vivo images of the gastro-intestinal tract is provided. A device, such as an autonomous capsule, includes at least one imaging unit; a control unit connected to the imaging unit and a power supply connected to the control unit. The control unit includes a switching unit and an axial motion detector connected to the switching unit. The axial motion detector detects the axial movement of the device and if the axial acceleration is below a pre-determined threshold, disconnects the power supply thereby preventing the acquisition of redundant images. A method for operation and use of the device is provided.

Abstract: The present invention provides a system and method for obtaining in vivo images. The system contains an imaging system and an ultra low power radio frequency transmitter for transmitting signals from the CMOS imaging camera to a receiving system located outside a patient. The imaging system includes at least one CMOS imaging camera, at least one illumination source for illuminating an in vivo site and an optical system for imaging the in vivo site onto the CMOS imaging camera.

Abstract: A sensing device includes a propulsion system that is typically substantially or completely within the sensing device. The propulsion system may include, for example, a rotatable propeller. The sensing device may be an in-vivo autonomous capsule with an imager, but may be another type of sensing device.

Abstract: Capsule (60) moves through the gastrointestinal tract (62) in a first pass to generate a map of the gastrointestinal tract, and to identify a location of interest. In its second pass, capsule (60) moves through the gastrointestinal tract, and is controlled to perform a job at the identified location. Repeated localizations generate generate a map of the route taken by the capsule in the gastrointestinal tract (62). images displayed on the image monitor (61) are compared with the generated map displayed on the position monitor (63) to identify the location of a pathology (72).